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A Qualitative Study Exploring the Determinants, Coping, and Effects of Stress in United Kingdom Trainee Doctors.

Zhou AY, Money A, Bower P, Van Tongeren M, Esmail A, Agius R.

Acad Psychiatry. 2019 Jul 9. doi: 10.1007/s40596-019-01086-y. [Epub ahead of print]


Same day tools, including Xpert Ultra and unstimulated IFN-γ, for the rapid diagnosis of pleural tuberculosis - a prospective observational study.

Meldau R, Randall P, Pooran A, Limberis J, Makambwa E, Dhansay M, Esmail A, Dheda K.

J Clin Microbiol. 2019 Jul 3. pii: JCM.00614-19. doi: 10.1128/JCM.00614-19. [Epub ahead of print]


Challenges for dedicated smoking cessation services in developing countries.

Tadzimirwa GY, Day C, Esmail A, Cooper C, Kamkuemah M, Dheda K, Van Zyl-Smit RN.

S Afr Med J. 2019 May 31;109(6):431-436. doi: 10.7196/SAMJ.2019.v109i6.13631.


3D-printed electrospinning setup for the preparation of loratadine nanofibers with enhanced physicochemical properties.

Ambrus R, Alshweiat A, Csóka I, Ovari G, Esmail A, Radacsi N.

Int J Pharm. 2019 Jun 21;567:118455. doi: 10.1016/j.ijpharm.2019.118455. [Epub ahead of print]


18F-PSMA 1007 Brain PET/CT Imaging in Glioma Recurrence.

Marafi F, Sasikumar A, Fathallah W, Esmail A.

Clin Nucl Med. 2019 Jun 1. doi: 10.1097/RLU.0000000000002668. [Epub ahead of print]


Dance your stress away: comparing the effect of dance/movement training to aerobic exercise training on the cortisol awakening response in healthy older adults.

Vrinceanu T, Esmail A, Berryman N, Predovan D, Vu TTM, Villalpando JM, Pruessner JC, Bherer L.

Stress. 2019 May 24:1-9. doi: 10.1080/10253890.2019.1617690. [Epub ahead of print]


Linezolid interruption in patients with fluoroquinolone-resistant tuberculosis receiving a bedaquiline-based treatment regimen.

Olayanju O, Esmail A, Limberis J, Gina P, Dheda K.

Int J Infect Dis. 2019 May 14;85:74-79. doi: 10.1016/j.ijid.2019.04.028. [Epub ahead of print]


Alone But Supported: A Qualitative Study of an HIV Self-testing App in an Observational Cohort Study in South Africa.

Janssen R, Engel N, Esmail A, Oelofse S, Krumeich A, Dheda K, Pai NP.

AIDS Behav. 2019 May 2. doi: 10.1007/s10461-019-02516-6. [Epub ahead of print]


Association of anti-tuberculosis drug concentrations in hair and treatment outcomes in MDR- and XDR-TB.

Metcalfe J, Bacchetti P, Gerona R, Esmail A, Dheda K, Gandhi M.

ERJ Open Res. 2019 Apr 26;5(2). pii: 00046-2019. doi: 10.1183/23120541.00046-2019. eCollection 2019 Apr.


68Ga-Prostate-Specific Membrane Antigen PET/CT in Cholangiocarcinoma: A Potential Biomarker for Targeted Radioligand Therapy?

Marafi F, Usmani S, Esmail A.

Clin Nucl Med. 2019 Jul;44(7):e439-e441. doi: 10.1097/RLU.0000000000002563.


Unrecognized bipolar disorder in patients with depression managed in primary care: A systematic review and meta-analysis.

Daveney J, Panagioti M, Waheed W, Esmail A.

Gen Hosp Psychiatry. 2019 May - Jun;58:71-76. doi: 10.1016/j.genhosppsych.2019.03.006. Epub 2019 Mar 27. Review.


Clarifications Needed on Study of Association Between Physician Burnout and Patient Safety-Reply.

Panagioti M, Hodkinson A, Esmail A.

JAMA Intern Med. 2019 Mar 4. doi: 10.1001/jamainternmed.2019.0152. [Epub ahead of print] No abstract available.


Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection.

Wasserman S, Denti P, Brust JCM, Abdelwahab M, Hlungulu S, Wiesner L, Norman J, Sirgel FA, Warren RM, Esmail A, Dheda K, Gandhi NR, Meintjes G, Maartens G.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02164-18. doi: 10.1128/AAC.02164-18. Print 2019 Mar.


Relationship between chest radiographic characteristics, sputum bacterial load, and treatment outcomes in patients with extensively drug-resistant tuberculosis.

Te Riele JB, Buser V, Calligaro G, Esmail A, Theron G, Lesosky M, Dheda K.

Int J Infect Dis. 2019 Feb;79:65-71. doi: 10.1016/j.ijid.2018.10.026. Epub 2018 Nov 3.


Identification of Fungal Pathogens in Otomycosis and Their Drug Sensitivity: Our Experience.

Ali K, Hamed MA, Hassan H, Esmail A, Sheneef A.

Int Arch Otorhinolaryngol. 2018 Oct;22(4):400-403. doi: 10.1055/s-0038-1626702. Epub 2018 Apr 12.


The clinical significance of incidental soft tissue uptake on whole body 18F-sodium fluoride bone PET-CT.

Usmani S, Gnanasegaran G, Marafi F, Esmail A, Ahmed N, Van den Wyngaert T.

Clin Radiol. 2019 Feb;74(2):95-110. doi: 10.1016/j.crad.2018.09.007. Epub 2018 Oct 17. Review.


National hospital mortality surveillance system: a descriptive analysis.

Cecil E, Wilkinson S, Bottle A, Esmail A, Vincent C, Aylin PP.

BMJ Qual Saf. 2018 Dec;27(12):974-981. doi: 10.1136/bmjqs-2018-008364. Epub 2018 Oct 8.


An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells.

Tomasicchio M, Semple L, Esmail A, Meldau R, Randall P, Pooran A, Davids M, Cairncross L, Anderson D, Downs J, Malherbe F, Novitzky N, Panieri E, Oelofse S, Londt R, Naiker T, Dheda K.

Cancer Immunol Immunother. 2019 Jan;68(1):71-83. doi: 10.1007/s00262-018-2238-5. Epub 2018 Oct 3.


Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017, Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fréchet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Laborín R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D.

Lancet. 2018 Sep 8;392(10150):821-834. doi: 10.1016/S0140-6736(18)31644-1. Review.


Implications of Pyran Cyclization and Pterin Conformation on Oxidized Forms of the Molybdenum Cofactor.

Gisewhite DR, Yang J, Williams BR, Esmail A, Stein B, Kirk ML, Burgmayer SJN.

J Am Chem Soc. 2018 Oct 10;140(40):12808-12818. doi: 10.1021/jacs.8b05777. Epub 2018 Oct 2.


Safety work and risk management as burdens of treatment in primary care: insights from a focused ethnographic study of patients with multimorbidity.

Daker-White G, Hays R, Blakeman T, Croke S, Brown B, Esmail A, Bower P.

BMC Fam Pract. 2018 Sep 8;19(1):155. doi: 10.1186/s12875-018-0844-0.


Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis.

Panagioti M, Geraghty K, Johnson J, Zhou A, Panagopoulou E, Chew-Graham C, Peters D, Hodkinson A, Riley R, Esmail A.

JAMA Intern Med. 2018 Oct 1;178(10):1317-1330. doi: 10.1001/jamainternmed.2018.3713. Erratum in: JAMA Intern Med. 2019 Mar 4;:.


Outcomes of patients with drug-resistant-tuberculosis treated with bedaquiline-containing regimens and undergoing adjunctive surgery.

Borisov SE, D'Ambrosio L, Centis R, Tiberi S, Dheda K, Alffenaar JW, Amale R, Belilowski E, Bruchfeld J, Canneto B, Denholm J, Duarte R, Esmail A, Filippov A, Davies Forsman L, Gaga M, Ganatra S, Igorevna GA, Lazaro Mastrapa B, Manfrin V, Manga S, Maryandyshev A, Massard G, González Montaner P, Mullerpattan J, Palmero DJ, Pontarelli A, Papavasileiou A, Pontali E, Romero Leyet R, Spanevello A, Udwadia ZF, Viggiani P, Visca D, Sotgiu G, Migliori GB.

J Infect. 2019 Jan;78(1):35-39. doi: 10.1016/j.jinf.2018.08.003. Epub 2018 Aug 7.


Polypharmacy in older patients with chronic diseases: a cross-sectional analysis of factors associated with excessive polypharmacy.

Rieckert A, Trampisch US, Klaaßen-Mielke R, Drewelow E, Esmail A, Johansson T, Keller S, Kunnamo I, Löffler C, Mäkinen J, Piccoliori G, Vögele A, Sönnichsen A.

BMC Fam Pract. 2018 Jul 18;19(1):113. doi: 10.1186/s12875-018-0795-5.


Technical feasibility, radiation dosimetry and clinical use of 18F-sodium fluoride (NaF) in evaluation of metastatic bone disease in pediatric population.

Usmani S, Van den Wyngaert T, Ahmed N, Marafi F, Esmail A, Al Kandari F, Al Nuaimi M, Gnanasegaran G.

Ann Nucl Med. 2018 Nov;32(9):594-601. doi: 10.1007/s12149-018-1279-3. Epub 2018 Jul 17.


Dorsal Radiocarpal Joint Fracture-Dislocation: A Case Report.

Yang PR, Patel AD, Esmail AN.

JBJS Case Connect. 2018 Jul-Sep;8(3):e50. doi: 10.2106/JBJS.CC.17.00275.


General practice: new technology isn't necessarily better.

Esmail A.

BMJ. 2018 Jul 2;362:k2829. doi: 10.1136/bmj.k2829. No abstract available.


Frequency and nature of potentially harmful preventable problems in primary care from the patient's perspective with clinician review: a population-level survey in Great Britain.

Stocks SJ, Donnelly A, Esmail A, Beresford J, Luty S, Deacon R, Danczak A, Mann N, Townsend D, Ashley J, Gamble C, Bowie P, Campbell SM.

BMJ Open. 2018 Jun 13;8(6):e020952. doi: 10.1136/bmjopen-2017-020952.


Investigating the association of alerts from a national mortality surveillance system with subsequent hospital mortality in England: an interrupted time series analysis.

Cecil E, Bottle A, Esmail A, Wilkinson S, Vincent C, Aylin PP.

BMJ Qual Saf. 2018 Dec;27(12):965-973. doi: 10.1136/bmjqs-2017-007495. Epub 2018 May 4.


Long-term bedaquiline-related treatment outcomes in patients with extensively drug-resistant tuberculosis from South Africa.

Olayanju O, Limberis J, Esmail A, Oelofse S, Gina P, Pietersen E, Fadul M, Warren R, Dheda K.

Eur Respir J. 2018 May 30;51(5). pii: 1800544. doi: 10.1183/13993003.00544-2018. Print 2018 May.


The role of clothing in participation of persons with a physical disability: a scoping review protocol.

Esmail A, Poncet F, Rochette A, Auger C, Billebaud C, de Guise É, Ducharme I, Kehayia E, Labbé D, Dahan-Oliel N, Lessard I, Vermeersch O, Swaine B.

BMJ Open. 2018 Mar 8;8(3):e020299. doi: 10.1136/bmjopen-2017-020299. Review.


Evaluation of a national surveillance system for mortality alerts: a mixed-methods study.

Aylin P, Bottle A, Burnett S, Cecil E, Charles KL, Dawson P, D’Lima D, Esmail A, Vincent C, Wilkinson S, Benn J.

Southampton (UK): NIHR Journals Library; 2018 Feb. No abstract available.

Free Books & Documents

A Patient Safety Toolkit for Family Practices.

Campbell SM, Bell BG, Marsden K, Spencer R, Kadam U, Perryman K, Rodgers S, Litchfield I, Reeves D, Chuter A, Doos L, Ricci-Cabello I, Gill P, Esmail A, Greenfield S, Slight S, Middleton K, Barnett J, Moore M, Valderas JM, Sheikh A, Avery AJ.

J Patient Saf. 2018 Feb 15. doi: 10.1097/PTS.0000000000000471. [Epub ahead of print]


Development and piloting of a survey to estimate the frequency and nature of potentially harmful preventable problems in primary care from a UK patient's perspective.

Stocks SJ, Donnelly A, Esmail A, Beresford J, Gamble C, Luty S, Deacon R, Danczak A, Mann N, Townsend D, Ashley J, Bowie P, Campbell SM.

BMJ Open. 2018 Feb 3;8(2):e017786. doi: 10.1136/bmjopen-2017-017786.


A qualitative study of tobacco interventions for LGBTQ+ youth and young adults: overarching themes and key learnings.

Bruce Baskerville N, Wong K, Shuh A, Abramowicz A, Dash D, Esmail A, Kennedy R.

BMC Public Health. 2018 Jan 18;18(1):155. doi: 10.1186/s12889-018-5050-4.


False-Positive Xpert MTB/RIF Results in Retested Patients with Previous Tuberculosis: Frequency, Profile, and Prospective Clinical Outcomes.

Theron G, Venter R, Smith L, Esmail A, Randall P, Sood V, Oelfese S, Calligaro G, Warren R, Dheda K.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01696-17. doi: 10.1128/JCM.01696-17. Print 2018 Mar.


Initial experience with 18F-sodium fluoride (NaF) PET-CT: a viable functional biomarker in symptomatic Os acromiale.

Usmani S, Marafi F, Esmail A, Ahmed N.

Br J Radiol. 2018 Apr;91(1084):20170741. doi: 10.1259/bjr.20170741. Epub 2018 Jan 12.


Diagnosing tuberculosis in hospitalized HIV-infected individuals who cannot produce sputum: is urine lipoarabinomannan testing the answer?

Sabur NF, Esmail A, Brar MS, Dheda K.

BMC Infect Dis. 2017 Dec 28;17(1):803. doi: 10.1186/s12879-017-2914-7.


Threats to patient safety in primary care reported by older people with multimorbidity: baseline findings from a longitudinal qualitative study and implications for intervention.

Hays R, Daker-White G, Esmail A, Barlow W, Minor B, Brown B, Blakeman T, Sanders C, Bower P.

BMC Health Serv Res. 2017 Nov 21;17(1):754. doi: 10.1186/s12913-017-2727-9.


Effectiveness and patient safety of platelet aggregation inhibitors in the prevention of cardiovascular disease and ischemic stroke in older adults - a systematic review.

Meinshausen M, Rieckert A, Renom-Guiteras A, Kröger M, Sommerauer C, Kunnamo I, Martinez YV, Esmail A, Sönnichsen A.

BMC Geriatr. 2017 Oct 16;17(Suppl 1):225. doi: 10.1186/s12877-017-0572-7. Review.


A set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol.

Martinez YV, Renom-Guiteras A, Reeves D, Erandie Ediriweera de Silva R, Esmail A, Kunnamo I, Rieckert A, Sommerauer C, Sönnichsen A.

BMC Geriatr. 2017 Oct 16;17(Suppl 1):231. doi: 10.1186/s12877-017-0570-9.


A proof-of-concept study analyzing the clinical utility of fluorine-18-sodium fluoride PET-CT in skeletal staging of oncology patients with end-stage renal disease on dialysis.

Usmani S, Marafi F, Esmail A, Ahmed N.

Nucl Med Commun. 2017 Dec;38(12):1067-1075. doi: 10.1097/MNM.0000000000000759.


Diagnostic Challenge of Staging Metastatic Bone Disease in the Morbidly Obese Patients: A Primary Study Evaluating the Usefulness of 18F-Sodium Fluoride (NaF) PET-CT.

Usmani S, Marafi F, Ahmed N, Esmail A, Al Kandari F, Van den Wyngaert T.

Clin Nucl Med. 2017 Nov;42(11):829-836. doi: 10.1097/RLU.0000000000001823.


Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?

Dheda K, Cox H, Esmail A, Wasserman S, Chang KC, Lange C.

Respirology. 2018 Jan;23(1):36-45. doi: 10.1111/resp.13143. Epub 2017 Aug 29. Review.


Managing diagnostic uncertainty in primary care: a systematic critical review.

Alam R, Cheraghi-Sohi S, Panagioti M, Esmail A, Campbell S, Panagopoulou E.

BMC Fam Pract. 2017 Aug 7;18(1):79. doi: 10.1186/s12875-017-0650-0. Review.


Novel weight-based dose threshold for 18F-NaF PET-CT imaging using advanced PET-CT systems: a potential tool for reducing radiation burden.

Marafi F, Esmail A, Rasheed R, Alkandari F, Usmani S.

Nucl Med Commun. 2017 Sep;38(9):764-770. doi: 10.1097/MNM.0000000000000706.


Patients' evaluations of patient safety in English general practices: a cross-sectional study.

Ricci-Cabello I, Marsden KS, Avery AJ, Bell BG, Kadam UT, Reeves D, Slight SP, Perryman K, Barnett J, Litchfield I, Thomas S, Campbell SM, Doos L, Esmail A, Valderas JM.

Br J Gen Pract. 2017 Jul;67(660):e474-e482. doi: 10.3399/bjgp17X691085. Epub 2017 Jun 5.

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