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Items: 28


Genes responsive to rapamycin and serum deprivation are clustered on chromosomes and undergo re-organization within local chromatin environments.

Belak ZR, Pickering JA, Gillespie ZE, Audette GF, Eramian M, Mitchell JA, Bridger JM, Kusalik A, Eskiw CH.

Biochem Cell Biol. 2019 Sep 3. doi: 10.1139/bcb-2019-0096. [Epub ahead of print]


A rapid, high-throughput method for determining chronological lifespan in budding yeast.

Belak ZR, Harkness T, Eskiw CH.

J Biol Methods. 2018 Dec 18;5(4):e106. doi: 10.14440/jbm.2018.272. eCollection 2018.


Metformin induces the AP-1 transcription factor network in normal dermal fibroblasts.

Gillespie ZE, Wang C, Vadan F, Yu TY, Ausió J, Kusalik A, Eskiw CH.

Sci Rep. 2019 Mar 29;9(1):5369. doi: 10.1038/s41598-019-41839-1.


Metformin alters H2A.Z dynamics and regulates androgen dependent prostate cancer progression.

Tyagi M, Cheema MS, Dryhurst D, Eskiw CH, Ausió J.

Oncotarget. 2018 Dec 11;9(97):37054-37068. doi: 10.18632/oncotarget.26457. eCollection 2018 Dec 11.


GrapHi-C: graph-based visualization of Hi-C datasets.

MacKay K, Kusalik A, Eskiw CH.

BMC Res Notes. 2018 Jun 29;11(1):418. doi: 10.1186/s13104-018-3507-2.


Conserved RNA binding activity of a Yin-Yang 1 homologue in the ova of the purple sea urchin Strongylocentrotus purpuratus.

Belak ZR, Ovsenek N, Eskiw CH.

Sci Rep. 2018 May 23;8(1):8061. doi: 10.1038/s41598-018-26264-0.


Rapid Nuclear Exclusion of Hcm1 in Aging Saccharomyces cerevisiae Leads to Vacuolar Alkalization and Replicative Senescence.

Ghavidel A, Baxi K, Prusinkiewicz M, Swan C, Belak ZR, Eskiw CH, Carvalho CE, Harkness TA.

G3 (Bethesda). 2018 May 4;8(5):1579-1592. doi: 10.1534/g3.118.200161.


Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan.

Gillespie ZE, Pickering J, Eskiw CH.

Front Genet. 2016 Aug 18;7:142. doi: 10.3389/fgene.2016.00142. eCollection 2016. Review.


Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/B-mediated cytokine production.

Gillespie ZE, MacKay K, Sander M, Trost B, Dawicki W, Wickramarathna A, Gordon J, Eramian M, Kill IR, Bridger JM, Kusalik A, Mitchell JA, Eskiw CH.

Nucleus. 2015;6(6):490-506. doi: 10.1080/19491034.2015.1128610.


Concordance between RNA-sequencing data and DNA microarray data in transcriptome analysis of proliferative and quiescent fibroblasts.

Trost B, Moir CA, Gillespie ZE, Kusalik A, Mitchell JA, Eskiw CH.

R Soc Open Sci. 2015 Sep 30;2(9):150402. doi: 10.1098/rsos.150402. eCollection 2015 Sep.


Nuclear RNA sequencing of the mouse erythroid cell transcriptome.

Mitchell JA, Clay I, Umlauf D, Chen CY, Moir CA, Eskiw CH, Schoenfelder S, Chakalova L, Nagano T, Fraser P.

PLoS One. 2012;7(11):e49274. doi: 10.1371/journal.pone.0049274. Epub 2012 Nov 29.


Progeria Research Day at Brunel University.

Bridger JM, Eskiw CH, Makarov EM, Tree D, Kill IR.

Nucleus. 2011 Nov-Dec;2(6):517-22. doi: 10.4161/nucl.2.6.17605. Epub 2011 Nov 1. Review.


Ultrastructural study of transcription factories in mouse erythroblasts.

Eskiw CH, Fraser P.

J Cell Sci. 2011 Nov 1;124(Pt 21):3676-83. doi: 10.1242/jcs.087981. Epub 2011 Nov 1.


Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.

Mehta IS, Eskiw CH, Arican HD, Kill IR, Bridger JM.

Genome Biol. 2011 Aug 12;12(8):R74. doi: 10.1186/gb-2011-12-8-r74.


Transcription factories and nuclear organization of the genome.

Eskiw CH, Cope NF, Clay I, Schoenfelder S, Nagano T, Fraser P.

Cold Spring Harb Symp Quant Biol. 2010;75:501-6. doi: 10.1101/sqb.2010.75.046. Epub 2011 Apr 5.


Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv.

Pink RC, Eskiw CH, Caley DP, Carter DR.

PLoS One. 2010 Sep 29;5(9). pii: e13045. doi: 10.1371/journal.pone.0013045.


The yin and yang of chromatin spatial organization.

Cope NF, Fraser P, Eskiw CH.

Genome Biol. 2010;11(3):204. doi: 10.1186/gb-2010-11-3-204. Epub 2010 Mar 29. Review.


Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells.

Schoenfelder S, Sexton T, Chakalova L, Cope NF, Horton A, Andrews S, Kurukuti S, Mitchell JA, Umlauf D, Dimitrova DS, Eskiw CH, Luo Y, Wei CL, Ruan Y, Bieker JJ, Fraser P.

Nat Genet. 2010 Jan;42(1):53-61. doi: 10.1038/ng.496. Epub 2009 Dec 13.


RNA polymerase II activity is located on the surface of protein-rich transcription factories.

Eskiw CH, Rapp A, Carter DR, Cook PR.

J Cell Sci. 2008 Jun 15;121(Pt 12):1999-2007. doi: 10.1242/jcs.027250. Epub 2008 May 21.


Where shall we meet? A role for genome organisation and nuclear sub-compartments in mediating interchromosomal interactions.

Osborne CS, Eskiw CH.

J Cell Biochem. 2008 Aug 1;104(5):1553-61. doi: 10.1002/jcb.21750. Review.


Transcriptional regulation is affected by subnuclear targeting of reporter plasmids to PML nuclear bodies.

Block GJ, Eskiw CH, Dellaire G, Bazett-Jones DP.

Mol Cell Biol. 2006 Dec;26(23):8814-25. Epub 2006 Sep 11.


Mitotic accumulations of PML protein contribute to the re-establishment of PML nuclear bodies in G1.

Dellaire G, Eskiw CH, Dehghani H, Ching RW, Bazett-Jones DP.

J Cell Sci. 2006 Mar 15;119(Pt 6):1034-42. Epub 2006 Feb 21.


PML bodies: a meeting place for genomic loci?

Ching RW, Dellaire G, Eskiw CH, Bazett-Jones DP.

J Cell Sci. 2005 Mar 1;118(Pt 5):847-54.


In situ imaging and isolation of proteins using dsDNA oligonucleotides.

Dellaire G, Nisman R, Eskiw CH, Bazett-Jones DP.

Nucleic Acids Res. 2004 Nov 23;32(20):e165.


Chromatin contributes to structural integrity of promyelocytic leukemia bodies through a SUMO-1-independent mechanism.

Eskiw CH, Dellaire G, Bazett-Jones DP.

J Biol Chem. 2004 Mar 5;279(10):9577-85. Epub 2003 Dec 12.


Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly.

Eskiw CH, Dellaire G, Mymryk JS, Bazett-Jones DP.

J Cell Sci. 2003 Nov 1;116(Pt 21):4455-66. Epub 2003 Sep 16.


The promyelocytic leukemia nuclear body: sites of activity?

Eskiw CH, Bazett-Jones DP.

Biochem Cell Biol. 2002;80(3):301-10. Review.


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