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Items: 1 to 50 of 111

1.

Alcohol-preferring rats show decreased corticotropin-releasing hormone-2 receptor expression and differences in HPA activation compared to alcohol-nonpreferring rats.

Yong W, Spence JP, Eskay R, Fitz SD, Damadzic R, Lai D, Foroud T, Carr LG, Shekhar A, Chester JA, Heilig M, Liang T.

Alcohol Clin Exp Res. 2014 May;38(5):1275-83. doi: 10.1111/acer.12379. Epub 2014 Mar 10.

2.

A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats.

Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, Zheng W, Heilig M.

J Neurosci. 2013 Jun 12;33(24):10132-42. doi: 10.1523/JNEUROSCI.4742-12.2013.

3.

Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats.

Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M.

Biol Psychiatry. 2013 Apr 15;73(8):774-81. doi: 10.1016/j.biopsych.2012.12.027. Epub 2013 Feb 16.

4.

Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective.

Cippitelli A, Damadzic R, Hamelink C, Brunnquell M, Thorsell A, Heilig M, Eskay RL.

Addict Biol. 2014 Jan;19(1):27-36. doi: 10.1111/j.1369-1600.2012.00451.x. Epub 2012 Apr 13.

5.

Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats.

Cippitelli A, Damadzic R, Singley E, Thorsell A, Ciccocioppo R, Eskay RL, Heilig M.

Pharmacol Biochem Behav. 2012 Jan;100(3):522-9. doi: 10.1016/j.pbb.2011.10.016. Epub 2011 Oct 20.

6.

Identification of Small Molecule Antagonists of the Neuropeptide-S Receptor.

Patnaik S, Marugan J, Liu K, Zheng W, Thorsell A, Eskay R, Southall N, Heilig M, Inglese J, Austin C.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Mar 19 [updated 2010 Dec 16].

7.

Identification of Functionally Selective Small Molecule Antagonists of the Neuropeptide-S Receptor: Naphthopyranopyrimidines.

Marugan J, Liu K, Zheng W, Eskay R, Southall N, Heilig M, Inglese J, Austin C.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2009 Feb 13 [updated 2010 Sep 2].

8.

Reversibility of object recognition but not spatial memory impairment following binge-like alcohol exposure in rats.

Cippitelli A, Zook M, Bell L, Damadzic R, Eskay RL, Schwandt M, Heilig M.

Neurobiol Learn Mem. 2010 Nov;94(4):538-46. doi: 10.1016/j.nlm.2010.09.006. Epub 2010 Sep 16.

9.

Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.

Sommer WH, Lidström J, Sun H, Passer D, Eskay R, Parker SC, Witt SH, Zimmermann US, Nieratschker V, Rietschel M, Margulies EH, Palkovits M, Laucht M, Heilig M.

Hum Mutat. 2010 Aug;31(8):E1594-608. doi: 10.1002/humu.21299.

10.

A genetic determinant of the striatal dopamine response to alcohol in men.

Ramchandani VA, Umhau J, Pavon FJ, Ruiz-Velasco V, Margas W, Sun H, Damadzic R, Eskay R, Schoor M, Thorsell A, Schwandt ML, Sommer WH, George DT, Parsons LH, Herscovitch P, Hommer D, Heilig M.

Mol Psychiatry. 2011 Aug;16(8):809-17. doi: 10.1038/mp.2010.56. Epub 2010 May 18.

11.

Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats.

Hansson AC, Nixon K, Rimondini R, Damadzic R, Sommer WH, Eskay R, Crews FT, Heilig M.

Int J Neuropsychopharmacol. 2010 Jun;13(5):583-93. doi: 10.1017/S1461145710000246. Epub 2010 Mar 25.

12.

A multiplex calcium assay for identification of GPCR agonists and antagonists.

Liu K, Southall N, Titus SA, Inglese J, Eskay RL, Shinn P, Austin CP, Heilig MA, Zheng W.

Assay Drug Dev Technol. 2010 Jun;8(3):367-79. doi: 10.1089/adt.2009.0245.

13.

Alcohol-induced neurodegeneration, suppression of transforming growth factor-beta, and cognitive impairment in rats: prevention by group II metabotropic glutamate receptor activation.

Cippitelli A, Damadzic R, Frankola K, Goldstein A, Thorsell A, Singley E, Eskay RL, Heilig M.

Biol Psychiatry. 2010 May 1;67(9):823-30. doi: 10.1016/j.biopsych.2009.12.018. Epub 2010 Feb 4.

PMID:
20132926
14.

Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking.

Cippitelli A, Damadzic R, Hansson AC, Singley E, Sommer WH, Eskay R, Thorsell A, Heilig M.

Psychopharmacology (Berl). 2010 Feb;208(3):417-26. doi: 10.1007/s00213-009-1741-y. Epub 2009 Dec 10.

PMID:
20012021
15.

Endogenous PACAP acts as a stress response peptide to protect cerebellar neurons from ethanol or oxidative insult.

Vaudry D, Hamelink C, Damadzic R, Eskay RL, Gonzalez B, Eiden LE.

Peptides. 2005 Dec;26(12):2518-24. Epub 2005 Jul 11.

16.

Comparison of cannabidiol, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity.

Hamelink C, Hampson A, Wink DA, Eiden LE, Eskay RL.

J Pharmacol Exp Ther. 2005 Aug;314(2):780-8. Epub 2005 May 5.

17.

Leptin suppresses food intake and body weight in corticosterone-replaced adrenalectomized rats.

Gemmill ME, Eskay RL, Hall NL, Douglass LW, Castonguay TW.

J Nutr. 2003 Feb;133(2):504-9.

PMID:
12566491
18.

The effects of adrenalectomy and aldosterone replacement in transgenic mice expressing antisense RNA to the type 2 glucocorticoid receptor.

Castonguay TW, Beaulieu S, Eskay RL, Barden N, Kamara K, Khozin S, Lustberg L, Brown L.

Physiol Behav. 2002 Nov;77(2-3):417-23.

PMID:
12419418
19.

Interactions of Glucocorticoids, NPY and Hypothalamic Serotonin.

Habash T, Eskay RL, Kuenzel WJ, Castonguay TW.

Nutr Neurosci. 2000;3(3):183-92. doi: 10.1080/1028415X.2000.11747315.

PMID:
27414052
20.

High-fat diets and stress responsivity.

Kamara K, Eskay R, Castonguay T.

Physiol Behav. 1998 Apr;64(1):1-6.

PMID:
9661975
21.
22.

Alcohol, corticosteroids, energy utilization, and hippocampal endangerment.

Eskay RL, Chautard T, Torda T, Daoud RI, Hamelink C.

Ann N Y Acad Sci. 1995 Dec 29;771:105-14.

PMID:
8597391
23.
25.

Cytokine-induced activation of the neuroendocrine stress axis persists in endotoxin-tolerant mice.

Mefford IN, Masters CF, Heyes MP, Eskay RL.

Brain Res. 1991 Aug 23;557(1-2):327-30.

PMID:
1747764
26.

The origin of somatostatin-containing nerve fibers innervating the hypothalamic supraoptic nucleus.

Mezey E, Léránth C, Eskay R, Horváth S, Palkovits M.

Brain Res. 1991 Jul 19;554(1-2):293-8.

PMID:
1681988
27.
28.

Potential biochemical markers for the predisposition toward alcoholism.

Eskay R, Linnoila M.

Recent Dev Alcohol. 1991;9:41-51. Review.

PMID:
1758992
29.

Neuropeptide content and connectivity of the rat claustrum.

Eiden LE, Mezey E, Eskay RL, Beinfeld MC, Palkovits M.

Brain Res. 1990 Jul 23;523(2):245-50.

PMID:
1976024
30.

Hypothalamic-pituitary-adrenal axis functioning and cerebrospinal fluid corticotropin releasing hormone and corticotropin levels in alcoholics after recent and long-term abstinence.

Adinoff B, Martin PR, Bone GH, Eckardt MJ, Roehrich L, George DT, Moss HB, Eskay R, Linnoila M, Gold PW.

Arch Gen Psychiatry. 1990 Apr;47(4):325-30.

PMID:
2157379
31.

Interleukins, signal transduction, and the immune system-mediated stress response.

Eskay RL, Grino M, Chen HT.

Adv Exp Med Biol. 1990;274:331-43. Review.

PMID:
2239431
32.

Behavioral, hormonal and neurochemical characteristics of aggressive alpha-mice.

Hilakivi LA, Lister RG, Durcan MJ, Ota M, Eskay RL, Mefford I, Linnoila M.

Brain Res. 1989 Nov 13;502(1):158-66.

PMID:
2819452
33.

Single-dose ethanol administration activates the hypothalamic-pituitary-adrenal axis: exploration of the mechanism of action.

Thiagarajan AB, Mefford IN, Eskay RL.

Neuroendocrinology. 1989 Oct;50(4):427-32.

PMID:
2554177
34.
35.
36.

Effect of single and repeated electroconvulsive shock on the hypothalamic-pituitary-adrenal axis and plasma catecholamines in rats.

Thiagarajan AB, Gleiter CH, Mefford IN, Eskay RL, Nutt DJ.

Psychopharmacology (Berl). 1989;97(4):548-52.

PMID:
2543014
37.

Acute effect of intragastric ethanol administration on plasma levels of stress hormones.

Thiagarajan AB, Mefford IN, Eskay RL.

Adv Alcohol Subst Abuse. 1988;7(3-4):227-30.

PMID:
2851931
38.
39.

Atrial natriuretic peptide in the median eminence is of paraventricular nucleus origin.

Palkovits M, Eskay RL, Antoni FA.

Neuroendocrinology. 1987 Dec;46(6):542-4.

PMID:
2962008
40.

Barium distinguishes separate calcium targets for synthesis and secretion of peptides in neuroendocrine cells.

Waschek JA, Dave JR, Eskay RL, Eiden LE.

Biochem Biophys Res Commun. 1987 Jul 31;146(2):495-501.

PMID:
2956945
41.

Neurotensin in the rat median eminence: the possible sources of neurotensin-like fibers and varicosities in the external layer.

Kiss A, Palkovits M, Antoni FA, Eskay RL, Skirboll LR.

Brain Res. 1987 Jul 21;416(1):129-35.

PMID:
3304533
42.

Adrenergic regulation of beta-endorphin secretion from anterior pituitary in conscious rats: effects of thyroid state.

Ishac EJ, Eskay R, Hirata F, Axelrod J, Kunos G.

Endocrinology. 1987 Mar;120(3):1073-8.

PMID:
2948818
43.

Distribution and possible origin of beta-endorphin and ACTH in discrete brainstem nuclei of rats.

Palkovits M, Eskay RL.

Neuropeptides. 1987 Feb-Mar;9(2):123-37.

PMID:
3033542
46.

Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin.

Bannon MJ, Deutch AY, Tam SY, Zamir N, Eskay RL, Lee JM, Maggio JE, Roth RH.

Brain Res. 1986 Sep 3;381(2):393-6.

PMID:
2428438
47.
48.

Circulating atrial natriuretic peptides in conscious rats: regulation of release by multiple factors.

Eskay R, Zukowska-Grojec Z, Haass M, Dave JR, Zamir N.

Science. 1986 May 2;232(4750):636-9.

PMID:
2938258
49.

Opioid-mediated cardiovascular effects of clonidine in spontaneously hypertensive rats: elimination by neonatal treatment with monosodium glutamate.

Mosqueda-Garcia R, Eskay R, Zamir N, Palkovits M, Kunos G.

Endocrinology. 1986 May;118(5):1814-22.

PMID:
2938932
50.

The localization and characterization of substance P and substance K in striatonigral neurons.

Lee JM, McLean S, Maggio JE, Zamir N, Roth RH, Eskay RL, Bannon MJ.

Brain Res. 1986 Apr 16;371(1):152-4.

PMID:
2423184

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