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Items: 1 to 50 of 79

1.

Microsomal prostaglandin E synthase-1 promotes lung metastasis via SDF-1/CXCR4-mediated recruitment of CD11b+Gr1+MDSCs from bone marrow.

Takahashi R, Amano H, Ito Y, Eshima K, Satoh T, Iwamura M, Nakamura M, Kitasato H, Uematsu S, Raouf J, Jakobsson PJ, Akira S, Majima M.

Biomed Pharmacother. 2020 Jan;121:109581. doi: 10.1016/j.biopha.2019.109581. Epub 2019 Nov 10.

2.

A novel intraperitoneal therapy for gastric cancer with DFP-10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model.

Ando H, Fukushima M, Eshima K, Hasui T, Shimizu T, Ishima Y, Huang CL, Wada H, Ishida T.

Cancer Med. 2019 Dec;8(17):7313-7321. doi: 10.1002/cam4.2598. Epub 2019 Oct 14.

3.

The role of vascular endothelial growth factor receptor 1 tyrosine kinase signaling in bleomycin-induced pulmonary fibrosis.

Amano H, Mastui Y, Ito Y, Shibata Y, Betto T, Eshima K, Ogawa F, Satoh Y, Shibuya M, Majima M.

Biomed Pharmacother. 2019 Sep;117:109067. doi: 10.1016/j.biopha.2019.109067. Epub 2019 Jun 5.

4.
5.

Vascular endothelial growth factor receptor 1 tyrosine kinase signaling facilitates healing of DSS-induced colitis by accumulation of Tregs in ulcer area.

Betto T, Amano H, Ito Y, Eshima K, Yoshida T, Matsui Y, Yamane S, Inoue T, Otaka F, Kobayashi K, Koizumi W, Shibuya M, Majima M.

Biomed Pharmacother. 2019 Mar;111:131-141. doi: 10.1016/j.biopha.2018.12.021. Epub 2018 Dec 20.

6.

Risk Profile and 1-Year Outcome of Newly Diagnosed Atrial Fibrillation in Japan - Insights From GARFIELD-AF.

Koretsune Y, Etoh T, Katsuda Y, Suetsugu T, Kumeda K, Sakuma I, Eshima K, Shibuya M, Ando SI, Yokota N, Goto S, Pieper KS, Allu J, Kakkar AK; GARFIELD-AF Investigators.

Circ J. 2018 Dec 25;83(1):67-74. doi: 10.1253/circj.CJ-18-0655. Epub 2018 Dec 4.

7.

RAMP1 in Kupffer cells is a critical regulator in immune-mediated hepatitis.

Inoue T, Ito Y, Nishizawa N, Eshima K, Kojo K, Otaka F, Betto T, Yamane S, Tsujikawa K, Koizumi W, Majima M.

PLoS One. 2018 Nov 21;13(11):e0200432. doi: 10.1371/journal.pone.0200432. eCollection 2018.

8.

An Arrhythmogenic Large Coronary Artery Aneurysm.

Kakino T, Kawano Y, Eshima K.

Intern Med. 2018 Dec 1;57(23):3491-3492. doi: 10.2169/internalmedicine.1092-18. Epub 2018 Aug 10. No abstract available.

9.

Impact of the extent of low-voltage zone on outcomes after voltage-based catheter ablation for persistent atrial fibrillation.

Yamaguchi T, Tsuchiya T, Fukui A, Kawano Y, Otsubo T, Takahashi Y, Hirota K, Murotani K, Eshima K, Takahashi N.

J Cardiol. 2018 Nov;72(5):427-433. doi: 10.1016/j.jjcc.2018.04.010. Epub 2018 May 26.

10.

Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model.

Iizuka K, Jin C, Eshima K, Hong MH, Eshima K, Fukushima M.

Drug Des Devel Ther. 2018 Mar 29;12:673-683. doi: 10.2147/DDDT.S156635. eCollection 2018.

11.

Role of T-bet, the master regulator of Th1 cells, in the cytotoxicity of murine CD4+ T cells.

Eshima K, Misawa K, Ohashi C, Iwabuchi K.

Microbiol Immunol. 2018 May;62(5):348-356. doi: 10.1111/1348-0421.12586.

12.

Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice.

Nishizawa N, Ito Y, Eshima K, Ohkubo H, Kojo K, Inoue T, Raouf J, Jakobsson PJ, Uematsu S, Akira S, Narumiya S, Watanabe M, Majima M.

J Hepatol. 2018 Jul;69(1):110-120. doi: 10.1016/j.jhep.2018.02.009. Epub 2018 Feb 16.

PMID:
29458169
13.

Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo.

Iizuka K, Zhang C, Eshima K, Jin C, Eshima K, Fukushima M.

Int J Oncol. 2018 Mar;52(3):851-860. doi: 10.3892/ijo.2018.4246. Epub 2018 Jan 16.

PMID:
29344636
14.

Feasibility of total intravenous anesthesia by cardiologists with the support of anesthesiologists during catheter ablation of atrial fibrillation.

Yamaguchi T, Shimakawa Y, Mitsumizo S, Fukui A, Kawano Y, Otsubo T, Takahashi Y, Hirota K, Tsuchiya T, Eshima K.

J Cardiol. 2018 Jul;72(1):19-25. doi: 10.1016/j.jjcc.2017.12.008. Epub 2018 Jan 17.

15.

Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents.

Fukushima M, Iizuka K, Jin C, Zhang C, Hong M, Eshima K.

Drug Des Devel Ther. 2017 Jun 7;11:1693-1705. doi: 10.2147/DDDT.S128420. eCollection 2017.

16.

Ezetimibe in Combination With Statins Ameliorates Endothelial Dysfunction in Coronary Arteries After Stenting: The CuVIC Trial (Effect of Cholesterol Absorption Inhibitor Usage on Target Vessel Dysfunction After Coronary Stenting), a Multicenter Randomized Controlled Trial.

Takase S, Matoba T, Nakashiro S, Mukai Y, Inoue S, Oi K, Higo T, Katsuki S, Takemoto M, Suematsu N, Eshima K, Miyata K, Yamamoto M, Usui M, Sadamatsu K, Satoh S, Kadokami T, Hironaga K, Ichi I, Todaka K, Kishimoto J, Egashira K, Sunagawa K.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):350-358. doi: 10.1161/ATVBAHA.116.308388. Epub 2016 Dec 8.

PMID:
27932353
17.

Thromboxane A synthase enhances blood flow recovery from hindlimb ischemia.

Amano H, Nakamura M, Ito Y, Kakutani H, Eshima K, Kitasato H, Narumiya S, Majima M.

J Surg Res. 2016 Jul;204(1):153-63. doi: 10.1016/j.jss.2016.04.011. Epub 2016 Apr 22.

PMID:
27451882
18.

BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils.

Kojo K, Ito Y, Eshima K, Nishizawa N, Ohkubo H, Yokomizo T, Shimizu T, Watanabe M, Majima M.

Sci Rep. 2016 Jul 11;6:29650. doi: 10.1038/srep29650.

19.

Efficacy of Left Atrial Voltage-Based Catheter Ablation of Persistent Atrial Fibrillation.

Yamaguchi T, Tsuchiya T, Nakahara S, Fukui A, Nagamoto Y, Murotani K, Eshima K, Takahashi N.

J Cardiovasc Electrophysiol. 2016 Sep;27(9):1055-63. doi: 10.1111/jce.13019. Epub 2016 Jun 30.

PMID:
27235000
20.

Leucine-rich repeat kinase 2 is a regulator of B cell function, affecting homeostasis, BCR signaling, IgA production, and TI antigen responses.

Kubo M, Nagashima R, Ohta E, Maekawa T, Isobe Y, Kurihara M, Eshima K, Iwabuchi K, Sasaoka T, Azuma S, Melrose HL, Farrer MJ, Obata F.

J Neuroimmunol. 2016 Mar 15;292:1-8. doi: 10.1016/j.jneuroim.2016.01.005. Epub 2016 Jan 8.

PMID:
26943952
21.

Inhibitory function of NKT cells during early induction phase of nickel allergy.

Okuno H, Satoh M, Takeuchi E, Eshima K, Terashima M, Komotori J, Habu S, Tamauchi H, Iwabuchi K.

Immunobiology. 2016 Jul;221(7):833-8. doi: 10.1016/j.imbio.2016.01.012. Epub 2016 Jan 29.

PMID:
26868431
22.

[On the roles of NF-κB-inducing kinase in thymic T cell differentiation].

Eshima K.

Seikagaku. 2015 Dec;87(6):770-5. Review. Japanese. No abstract available.

PMID:
26863760
23.

Cooperation of Sox4 with β-catenin/p300 complex in transcriptional regulation of the Slug gene during divergent sarcomatous differentiation in uterine carcinosarcoma.

Inoue H, Takahashi H, Hashimura M, Eshima K, Akiya M, Matsumoto T, Saegusa M.

BMC Cancer. 2016 Feb 3;16:53. doi: 10.1186/s12885-016-2090-y.

24.

The Role of Vascular Endothelial Growth Factor Receptor-1 Signaling in the Recovery from Ischemia.

Amano H, Kato S, Ito Y, Eshima K, Ogawa F, Takahashi R, Sekiguchi K, Tamaki H, Sakagami H, Shibuya M, Majima M.

PLoS One. 2015 Jul 2;10(7):e0131445. doi: 10.1371/journal.pone.0131445. eCollection 2015.

25.

Differential dependence on nuclear factor-κB-inducing kinase among natural killer T-cell subsets in their development.

Noma H, Eshima K, Satoh M, Iwabuchi K.

Immunology. 2015 Sep;146(1):89-99. doi: 10.1111/imm.12484. Epub 2015 Jun 25.

26.

Thromboxane A2 induces blood flow recovery via platelet adhesion to ischaemic regions.

Amano H, Ito Y, Eshima K, Kato S, Ogawa F, Hosono K, Oba K, Tamaki H, Sakagami H, Shibuya M, Narumiya S, Majima M.

Cardiovasc Res. 2015 Sep 1;107(4):509-21. doi: 10.1093/cvr/cvv139. Epub 2015 May 1.

PMID:
25935870
27.

The role of vascular endothelial growth factor receptor-1 signaling in compensatory contralateral lung growth following unilateral pneumonectomy.

Matsui Y, Amano H, Ito Y, Eshima K, Tamaki H, Ogawa F, Iyoda A, Shibuya M, Kumagai Y, Satoh Y, Majima M.

Lab Invest. 2015 May;95(5):456-68. doi: 10.1038/labinvest.2014.159. Epub 2015 Feb 2.

28.

Prostanoid induces premetastatic niche in regional lymph nodes.

Ogawa F, Amano H, Eshima K, Ito Y, Matsui Y, Hosono K, Kitasato H, Iyoda A, Iwabuchi K, Kumagai Y, Satoh Y, Narumiya S, Majima M.

J Clin Invest. 2014 Nov;124(11):4882-94. doi: 10.1172/JCI73530. Epub 2014 Oct 1.

29.

VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury.

Ohkubo H, Ito Y, Minamino T, Eshima K, Kojo K, Okizaki S, Hirata M, Shibuya M, Watanabe M, Majima M.

PLoS One. 2014 Aug 27;9(8):e105533. doi: 10.1371/journal.pone.0105533. eCollection 2014.

30.

Significant involvement of nuclear factor-κB-inducing kinase in proper differentiation of αβ and γδ T cells.

Eshima K, Okabe M, Kajiura S, Noma H, Shinohara N, Iwabuchi K.

Immunology. 2014 Feb;141(2):222-32. doi: 10.1111/imm.12186.

31.

Vascular endothelial growth factor receptor 1 signaling facilitates gastric ulcer healing and angiogenesis through the upregulation of epidermal growth factor expression on VEGFR1+CXCR4 + cells recruited from bone marrow.

Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.

J Gastroenterol. 2014 Mar;49(3):455-69. doi: 10.1007/s00535-013-0869-z. Epub 2013 Aug 24.

PMID:
23982810
32.

NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4(+)VEGFR1(+) cells to the ulcer granulation tissues.

Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.

Biomed Pharmacother. 2013 Sep;67(7):607-13. doi: 10.1016/j.biopha.2013.01.009. Epub 2013 Jun 7.

PMID:
23809370
33.

Angiotensin II type 1A receptor signaling facilitates tumor metastasis formation through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.

Amano H, Ito Y, Ogawa F, Eshima K, Suzuki T, Oba K, Matsui Y, Kato S, Fukui T, Nakamura M, Kitasato H, Fukamizu A, Majima M.

Am J Pathol. 2013 Feb;182(2):553-64. doi: 10.1016/j.ajpath.2012.10.026. Epub 2012 Dec 3.

PMID:
23219751
34.

Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice.

Andoh Y, Ogura H, Satoh M, Shimano K, Okuno H, Fujii S, Ishimori N, Eshima K, Tamauchi H, Otani T, Nakai Y, Van Kaer L, Tsutsui H, Onoé K, Iwabuchi K.

Immunobiology. 2013 Apr;218(4):561-9. doi: 10.1016/j.imbio.2012.07.022. Epub 2012 Jul 27.

35.

Ectopic expression of a T-box transcription factor, eomesodermin, renders CD4(+) Th cells cytotoxic by activating both perforin- and FasL-pathways.

Eshima K, Chiba S, Suzuki H, Kokubo K, Kobayashi H, Iizuka M, Iwabuchi K, Shinohara N.

Immunol Lett. 2012 May 30;144(1-2):7-15. doi: 10.1016/j.imlet.2012.02.013. Epub 2012 Mar 10.

PMID:
22425747
36.

Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance.

Satoh M, Andoh Y, Clingan CS, Ogura H, Fujii S, Eshima K, Nakayama T, Taniguchi M, Hirata N, Ishimori N, Tsutsui H, Onoé K, Iwabuchi K.

PLoS One. 2012;7(2):e30568. doi: 10.1371/journal.pone.0030568. Epub 2012 Feb 22.

37.

Thromboxane A₂ receptor signaling facilitates tumor colonization through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.

Matsui Y, Amano H, Ito Y, Eshima K, Suzuki T, Ogawa F, Iyoda A, Satoh Y, Kato S, Nakamura M, Kitasato H, Narumiya S, Majima M.

Cancer Sci. 2012 Apr;103(4):700-7. doi: 10.1111/j.1349-7006.2012.02200.x. Epub 2012 Feb 2.

38.

Gene expression of mesenchyme forkhead 1 (FOXC2) significantly correlates with the degree of lymph node metastasis in colorectal cancer.

Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Kanazawa T, Tanaka T, Konishi T, Ikeuchi H, Eshima K, Muto T, Nagawa H.

Int Surg. 2011 Jul-Sep;96(3):207-16.

PMID:
22216698
39.

Nestin-positive hair follicle pluripotent stem cells can promote regeneration of impinged peripheral nerve injury.

Amoh Y, Aki R, Hamada Y, Niiyama S, Eshima K, Kawahara K, Sato Y, Tani Y, Hoffman RM, Katsuoka K.

J Dermatol. 2012 Jan;39(1):33-8. doi: 10.1111/j.1346-8138.2011.01413.x. Epub 2011 Nov 21.

PMID:
22098554
40.

Predicting ulcerative colitis-associated colorectal cancer using reverse-transcription polymerase chain reaction analysis.

Watanabe T, Kobunai T, Yamamoto Y, Ikeuchi H, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Kanazawa T, Tanaka T, Yokoyama T, Konishi T, Eshima K, Ajioka Y, Hibi T, Watanabe M, Muto T, Nagawa H.

Clin Colorectal Cancer. 2011 Jun;10(2):134-41. doi: 10.1016/j.clcc.2011.03.011. Epub 2011 Apr 22.

PMID:
21859567
41.

Heterogeneity of KRAS status may explain the subset of discordant KRAS status between primary and metastatic colorectal cancer.

Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Shibuya H, Eshima K.

Dis Colon Rectum. 2011 Sep;54(9):1170-8. doi: 10.1097/DCR.0b013e31821d37a3.

PMID:
21825899
42.

Gene expression signature and response to the use of leucovorin, fluorouracil and oxaliplatin in colorectal cancer patients.

Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Konishi T, Horie H, Ikeuchi H, Eshima K, Muto T.

Clin Transl Oncol. 2011 Jun;13(6):419-25. doi: 10.1007/s12094-011-0676-z.

PMID:
21680303
43.

Differential gene expression signatures between colorectal cancers with and without KRAS mutations: crosstalk between the KRAS pathway and other signalling pathways.

Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Ikeuchi H, Eshima K.

Eur J Cancer. 2011 Sep;47(13):1946-54. doi: 10.1016/j.ejca.2011.03.029. Epub 2011 Apr 29.

PMID:
21531130
44.

RUNX3 copy number predicts the development of UC-associated colorectal cancer.

Watanabe T, Kobunai T, Ikeuchi H, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K, Iinuma H, Kanazawa T, Tanaka T, Yokoyama T, Konishi T, Eshima K, Ajioka Y, Hibi T, Watanabe M, Muto T, Nagawa H.

Int J Oncol. 2011 Jan;38(1):201-7.

PMID:
21109941
45.

LRRK2 is expressed in B-2 but not in B-1 B cells, and downregulated by cellular activation.

Kubo M, Kamiya Y, Nagashima R, Maekawa T, Eshima K, Azuma S, Ohta E, Obata F.

J Neuroimmunol. 2010 Dec 15;229(1-2):123-8. doi: 10.1016/j.jneuroim.2010.07.021. Epub 2010 Aug 21.

PMID:
20728949
46.

Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes.

Watanabe T, Kobunai T, Yamamoto Y, Kanazawa T, Konishi T, Tanaka T, Matsuda K, Ishihara S, Nozawa K, Eshima K, Muto T, Nagawa H.

Eur J Cancer. 2010 Jul;46(11):2119-26. doi: 10.1016/j.ejca.2010.04.019. Epub 2010 Jun 1.

PMID:
20570135
47.

The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: a comparison between direct sequencing and real-time PCR.

Kobunai T, Watanabe T, Yamamoto Y, Eshima K.

Biochem Biophys Res Commun. 2010 Apr 23;395(1):158-62. doi: 10.1016/j.bbrc.2010.03.167. Epub 2010 Mar 31.

PMID:
20361930
48.

Effect of erythropoietin on angiogenesis with the increased adhesion of platelets to the microvessels in the hind-limb ischemia model in mice.

Kato S, Amano H, Ito Y, Eshima K, Aoyama N, Tamaki H, Sakagami H, Satoh Y, Izumi T, Majima M.

J Pharmacol Sci. 2010;112(2):167-75. Epub 2010 Feb 4.

49.

Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.

Patrick MS, Oda H, Hayakawa K, Sato Y, Eshima K, Kirikae T, Iemura S, Shirai M, Abe T, Natsume T, Sasazuki T, Suzuki H.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16345-50. doi: 10.1073/pnas.0908593106. Epub 2009 Sep 14.

50.

Coronary aneurysm associated with coronary perforation after sirolimus-eluting stents implantation: close follow-up exceeding 2 years by coronary 3-dimensional computed tomography.

Eshima K, Takemoto M, Inoue S, Higo T, Tada H, Sunagawa K.

J Cardiol. 2009 Aug;54(1):115-20. doi: 10.1016/j.jjcc.2008.09.013. Epub 2008 Nov 25.

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