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Items: 32


Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance.

Escudero JA, MacLean RC, San Millan A.

J Vis Exp. 2018 May 2;(135). doi: 10.3791/57386.


Recertification is comming. Afraid? Not al all.

García Romero M, Sistac Ballarín JM, Escudero JA.

Rev Esp Anestesiol Reanim. 2018 Jun - Jul;65(6):303-305. doi: 10.1016/j.redar.2018.03.001. Epub 2018 Apr 11. English, Spanish. No abstract available.


Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation.

Rodriguez-Beltran J, Hernandez-Beltran JCR, DelaFuente J, Escudero JA, Fuentes-Hernandez A, MacLean RC, Peña-Miller R, San Millan A.

Nat Ecol Evol. 2018 May;2(5):873-881. doi: 10.1038/s41559-018-0529-z. Epub 2018 Apr 9.


Genomic Plasticity of Vibrio cholerae.

Escudero JA, Mazel D.

Int Microbiol. 2017 Sep;20(3):138-148. doi: 10.2436/20.1501.01.295. Review.


Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation.

Escudero JA, Nivina A, Cambray G, López-Igual R, Loot C, Mazel D.

Biotechnol Bioeng. 2018 Jan;115(1):184-191. doi: 10.1002/bit.26450. Epub 2017 Oct 16.


Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria.

San Millan A, Escudero JA, Gifford DR, Mazel D, MacLean RC.

Nat Ecol Evol. 2016 Nov 7;1(1):10. doi: 10.1038/s41559-016-0010.


Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals.

Ovejero CM, Escudero JA, Thomas-Lopez D, Hoefer A, Moyano G, Montero N, Martin-Espada C, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02640-16. doi: 10.1128/AAC.02640-16. Print 2017 Jun.


Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance.

Loot C, Nivina A, Cury J, Escudero JA, Ducos-Galand M, Bikard D, Rocha EP, Mazel D.

MBio. 2017 Mar 28;8(2). pii: e02296-16. doi: 10.1128/mBio.02296-16.


Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites.

Nivina A, Escudero JA, Vit C, Mazel D, Loot C.

Nucleic Acids Res. 2016 Sep 19;44(16):7792-803. doi: 10.1093/nar/gkw646. Epub 2016 Aug 5.


Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation.

Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D.

Nat Commun. 2016 Mar 10;7:10937. doi: 10.1038/ncomms10937.


Sequencing of plasmids pAMBL1 and pAMBL2 from Pseudomonas aeruginosa reveals a blaVIM-1 amplification causing high-level carbapenem resistance.

San Millan A, Toll-Riera M, Escudero JA, Cantón R, Coque TM, MacLean RC.

J Antimicrob Chemother. 2015 Nov;70(11):3000-3. doi: 10.1093/jac/dkv222. Epub 2015 Jul 24.


The Integron: Adaptation On Demand.

Escudero JA, Loot C, Nivina A, Mazel D.

Microbiol Spectr. 2015 Apr;3(2):MDNA3-0019-2014. doi: 10.1128/microbiolspec.MDNA3-0019-2014. Review.


Culturable aerobic and facultative bacteria from the gut of the polyphagic dung beetle Thorectes lusitanicus.

Hernández N, Escudero JA, San Millán Á, González-Zorn B, Lobo JM, Verdú JR, Suárez M.

Insect Sci. 2015 Apr;22(2):178-90. doi: 10.1111/1744-7917.12094. Epub 2014 Apr 30.


The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites.

Loot C, Parissi V, Escudero JA, Amarir-Bouhram J, Bikard D, Mazel D.

J Bacteriol. 2014 Feb;196(4):762-71. doi: 10.1128/JB.01109-13. Epub 2013 Dec 2.


First identification of Salmonella Urbana and Salmonella Ouakam in humans in Africa.

Saba CK, Escudero JA, Herrera-Leon S, Porrero MC, Suarez M, Dominguez L, Demuyakor B, Gonzalez-Zorn B.

J Infect Dev Ctries. 2013 Oct 15;7(10):691-5. doi: 10.3855/jidc.3548.


Ecology of antimicrobial resistance: humans, animals, food and environment.

González-Zorn B, Escudero JA.

Int Microbiol. 2012 Sep;15(3):101-9. Review.


SatR is a repressor of fluoroquinolone efflux pump SatAB.

Escudero JA, San Millan A, Montero N, Gutierrez B, Ovejero CM, Carrilero L, González-Zorn B.

Antimicrob Agents Chemother. 2013 Jul;57(7):3430-3. doi: 10.1128/AAC.00515-13. Epub 2013 May 6.


Temporary epicardial left ventricular and biventricular pacing improves cardiac output after cardiopulmonary bypass.

García-Bengochea JB, Fernández AL, Calvelo DS, Escudero JA, Gude F, Juanatey JR.

J Cardiothorac Surg. 2012 Oct 22;7:113. doi: 10.1186/1749-8090-7-113.


High frequency percussive ventilation and low FiO(2).

Starnes-Roubaud M, Bales EA, Williams-Resnick A, Lumb PD, Escudero JA, Chan LS, Garner WL.

Burns. 2012 Nov;38(7):984-91. doi: 10.1016/j.burns.2012.05.026. Epub 2012 Jul 4.


Replicative resolution of integron cassette insertion.

Loot C, Ducos-Galand M, Escudero JA, Bouvier M, Mazel D.

Nucleic Acids Res. 2012 Sep 1;40(17):8361-70. Epub 2012 Jun 26.


Fitness cost and interference of Arm/Rmt aminoglycoside resistance with the RsmF housekeeping methyltransferases.

Gutierrez B, Escudero JA, San Millan A, Hidalgo L, Carrilero L, Ovejero CM, Santos-Lopez A, Thomas-Lopez D, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2012 May;56(5):2335-41. doi: 10.1128/AAC.06066-11. Epub 2012 Feb 13.


Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA.

Escudero JA, San Millan A, Gutierrez B, Hidalgo L, La Ragione RM, AbuOun M, Galimand M, Ferrándiz MJ, Domínguez L, de la Campa AG, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2011 Dec;55(12):5850-60. doi: 10.1128/AAC.00498-11. Epub 2011 Sep 19.


ArmA methyltransferase in a monophasic Salmonella enterica isolate from food.

Granier SA, Hidalgo L, San Millan A, Escudero JA, Gutierrez B, Brisabois A, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2011 Nov;55(11):5262-6. doi: 10.1128/AAC.00308-11. Epub 2011 Aug 22.


Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a β-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy.

San Millan A, Giufré M, Escudero JA, Hidalgo L, Gutierrez B, Cerquetti M, Gonzalez-Zorn B.

J Antimicrob Chemother. 2011 Jan;66(1):96-9. doi: 10.1093/jac/dkq392. Epub 2010 Oct 26.


16S rRNA methyltransferase RmtC in Salmonella enterica serovar Virchow.

Hopkins KL, Escudero JA, Hidalgo L, Gonzalez-Zorn B.

Emerg Infect Dis. 2010 Apr;16(4):712-5. doi: 10.3201/eid1604.090736.


Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination.

San Millan A, Garcia-Cobos S, Escudero JA, Hidalgo L, Gutierrez B, Carrilero L, Campos J, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2010 Apr;54(4):1506-11. doi: 10.1128/AAC.01489-09. Epub 2010 Jan 19.


Novel genetic environment of qnrB2 associated with TEM-1 and SHV-12 on pB1004, an IncHI2 plasmid, in Salmonella Bredeney BB1047 from Spain.

Gutierrez B, Herrera-Leon S, Escudero JA, Hidalgo L, Gonzalez-Sanz R, Arroyo M, San Millan A, Echeita MA, Gonzalez-Zorn B.

J Antimicrob Chemother. 2009 Dec;64(6):1334-6. doi: 10.1093/jac/dkp340. Epub 2009 Sep 22. No abstract available.


Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids.

San Millan A, Escudero JA, Gutierrez B, Hidalgo L, Garcia N, Llagostera M, Dominguez L, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2009 Aug;53(8):3399-404. doi: 10.1128/AAC.01522-08. Epub 2009 Jun 15.


Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1.

San Millan A, Escudero JA, Catalan A, Nieto S, Farelo F, Gibert M, Moreno MA, Dominguez L, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2007 Jun;51(6):2260-4. Epub 2007 Apr 16.


First characterization of fluoroquinolone resistance in Streptococcus suis.

Escudero JA, San Millan A, Catalan A, de la Campa AG, Rivero E, Lopez G, Dominguez L, Moreno MA, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2007 Feb;51(2):777-82. Epub 2006 Nov 20.


Genetic basis for dissemination of armA.

González-Zorn B, Catalan A, Escudero JA, Domínguez L, Teshager T, Porrero C, Moreno MA.

J Antimicrob Chemother. 2005 Sep;56(3):583-5. Epub 2005 Jul 18.


Can we improve the venous catheterization systems by Seldinger's method?

Escudero JA, Pérez AR.

Acta Anaesthesiol Scand. 1996 May;40(5):645. No abstract available.


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