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Items: 1 to 50 of 54

1.

Molecular basis of USP7 inhibition by selective small-molecule inhibitors.

Turnbull AP, Ioannidis S, Krajewski WW, Pinto-Fernandez A, Heride C, Martin ACL, Tonkin LM, Townsend EC, Buker SM, Lancia DR, Caravella JA, Toms AV, Charlton TM, Lahdenranta J, Wilker E, Follows BC, Evans NJ, Stead L, Alli C, Zarayskiy VV, Talbot AC, Buckmelter AJ, Wang M, McKinnon CL, Saab F, McGouran JF, Century H, Gersch M, Pittman MS, Marshall CG, Raynham TM, Simcox M, Stewart LMD, McLoughlin SB, Escobedo JA, Bair KW, Dinsmore CJ, Hammonds TR, Kim S, Urbé S, Clague MJ, Kessler BM, Komander D.

Nature. 2017 Oct 26;550(7677):481-486. doi: 10.1038/nature24451. Epub 2017 Oct 18.

2.

Intracellular acidosis and pH regulation in central respiratory chemoreceptors.

Ravindran CR, Bayne JN, Bravo SC, Busby T, Crain CN, Escobedo JA, Gresham K, O'Grady BJ, Rios L, Roy S, Gdovin MJ.

J Health Care Poor Underserved. 2011;22(4 Suppl):174-86. doi: 10.1353/hpu.2011.0168.

3.

Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors.

Rendahl KG, Quiroz D, Ladner M, Coyne M, Seltzer J, Manning WC, Escobedo JA.

Hum Gene Ther. 2002 Jan 20;13(2):335-42.

PMID:
11812288
4.

Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2.

Lau D, McGee LH, Zhou S, Rendahl KG, Manning WC, Escobedo JA, Flannery JG.

Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3622-33.

PMID:
11006261
5.

Dose response to a single intramuscular injection of recombinant adeno-associated virus-erythropoietin in monkeys.

Rudich SM, Zhou S, Srivastava R, Escobedo JA, Perez RV, Manning WC.

J Surg Res. 2000 May 15;90(2):102-8.

PMID:
10792948
6.
7.

Lipitoids--novel cationic lipids for cellular delivery of plasmid DNA in vitro.

Huang CY, Uno T, Murphy JE, Lee S, Hamer JD, Escobedo JA, Cohen FE, Radhakrishnan R, Dwarki V, Zuckermann RN.

Chem Biol. 1998 Jun;5(6):345-54.

8.

Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors.

Manning WC, Zhou S, Bland MP, Escobedo JA, Dwarki V.

Hum Gene Ther. 1998 Mar 1;9(4):477-85.

PMID:
9525309
9.
10.

Genetic immunization with adeno-associated virus vectors expressing herpes simplex virus type 2 glycoproteins B and D.

Manning WC, Paliard X, Zhou S, Pat Bland M, Lee AY, Hong K, Walker CM, Escobedo JA, Dwarki V.

J Virol. 1997 Oct;71(10):7960-2.

11.
12.

Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma.

Liao X, Escobedo JA, Williams LT.

J Investig Med. 1996 Apr;44(4):139-43.

PMID:
8689409
13.

Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways.

Kinashi T, Escobedo JA, Williams LT, Takatsu K, Springer TA.

Blood. 1995 Sep 15;86(6):2086-90.

PMID:
7545020
14.
16.

Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor.

Kamohara S, Hayashi H, Todaka M, Kanai F, Ishii K, Imanaka T, Escobedo JA, Williams LT, Ebina Y.

Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1077-81.

17.

Activation of Na+/H+ exchange by platelet-derived growth factor involves phosphatidylinositol 3'-kinase and phospholipase C gamma.

Ma YH, Reusch HP, Wilson E, Escobedo JA, Fantl WJ, Williams LT, Ives HE.

J Biol Chem. 1994 Dec 2;269(48):30734-9.

18.

[Cutaneous infection caused by Mycobacterium chelonae after self-injection of insulin using a jet injector].

Escobedo JA, Gil D, Pascual A, Aguirre JM.

Enferm Infecc Microbiol Clin. 1994 May;12(5):274-5. Spanish. No abstract available.

PMID:
8049299
19.

Evidence for both tyrosine kinase and G-protein-coupled pathways leading to starfish egg activation.

Shilling FM, Carroll DJ, Muslin AJ, Escobedo JA, Williams LT, Jaffe LA.

Dev Biol. 1994 Apr;162(2):590-9.

PMID:
8150217
20.

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity.

Klippel A, Escobedo JA, Hirano M, Williams LT.

Mol Cell Biol. 1994 Apr;14(4):2675-85.

21.

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta.

Kundra V, Escobedo JA, Kazlauskas A, Kim HK, Rhee SG, Williams LT, Zetter BR.

Nature. 1994 Feb 3;367(6462):474-6.

PMID:
8107807
24.
25.

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.

Satoh T, Fantl WJ, Escobedo JA, Williams LT, Kaziro Y.

Mol Cell Biol. 1993 Jun;13(6):3706-13.

26.

[Cirrhosis and cryptococcal meningitis].

Rubio-Félix SA, Aznar R, Escobedo JA, Mairal P.

Rev Clin Esp. 1992 Nov;191(7):396. Spanish. No abstract available.

PMID:
1475472
27.
28.

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways.

Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT.

Cell. 1992 May 1;69(3):413-23.

PMID:
1374684
30.

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.

de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT.

Science. 1992 Feb 21;255(5047):989-91.

PMID:
1312256
31.

Interactions of PDGF and FGF receptors with cytoplasmic signaling molecules.

Peters KG, Escobedo JA, Fantl WJ, Williams LT.

Cold Spring Harb Symp Quant Biol. 1992;57:63-6. Review. No abstract available.

PMID:
1339700
32.

Inhibition of PDGF beta receptor signal transduction by coexpression of a truncated receptor.

Ueno H, Colbert H, Escobedo JA, Williams LT.

Science. 1991 May 10;252(5007):844-8.

PMID:
1851331
33.

[Symptomatic right aortic arch in adults].

Escobedo JA, Martín I, Val P, Fusté R, Marín JM.

Med Clin (Barc). 1991 Apr 20;96(15):578-80. Spanish.

PMID:
2051816
34.

cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.

Escobedo JA, Navankasattusas S, Kavanaugh WM, Milfay D, Fried VA, Williams LT.

Cell. 1991 Apr 5;65(1):75-82.

PMID:
1849460
35.
36.

Identification of phosphotyrosine residues during protein sequence analysis.

Turck CW, Herrmann J, Escobedo JA, Williams LT.

Pept Res. 1991 Jan-Feb;4(1):36-9.

PMID:
1724944
37.

Chromosomal localization of the gene for AA-type platelet-derived growth factor receptor (PDGFRA) in humans and mice.

Hsieh CL, Navankasattusas S, Escobedo JA, Williams LT, Francke U.

Cytogenet Cell Genet. 1991;56(3-4):160-3.

PMID:
1711435
38.

Interactions of growth factor receptors with cytoplasmic signaling molecules.

Williams LT, Escobedo JA, Fantl WJ, Turck CW, Klippel A.

Cold Spring Harb Symp Quant Biol. 1991;56:243-50. Review.

PMID:
1668083
39.

Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines.

Harsh GR, Keating MT, Escobedo JA, Williams LT.

J Neurooncol. 1990 Feb;8(1):1-12.

PMID:
2156959
41.

Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor.

Morrison DK, Kaplan DR, Escobedo JA, Rapp UR, Roberts TM, Williams LT.

Cell. 1989 Aug 25;58(4):649-57.

PMID:
2475255
42.

Role of phosphatidylinositol kinase in PDGF receptor signal transduction.

Coughlin SR, Escobedo JA, Williams LT.

Science. 1989 Mar 3;243(4895):1191-4.

PMID:
2466336
43.
44.

Phosphatidylinositol linkage of a truncated form of the platelet-derived growth factor receptor.

Orchansky PL, Escobedo JA, Williams LT.

J Biol Chem. 1988 Oct 15;263(29):15159-65.

45.
46.

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

Escobedo JA, Williams LT.

Nature. 1988 Sep 1;335(6185):85-7.

PMID:
2842689
47.

A common PDGF receptor is activated by homodimeric A and B forms of PDGF.

Escobedo JA, Navankasatussas S, Cousens LS, Coughlin SR, Bell GI, Williams LT.

Science. 1988 Jun 10;240(4858):1532-4.

PMID:
2836953
48.
49.

Signal transduction by the platelet-derived growth factor receptor.

Williams LT, Escobedo JA, Keating MT, Coughlin SR.

Cold Spring Harb Symp Quant Biol. 1988;53 Pt 1:455-65. No abstract available.

PMID:
2855486
50.

Molecular mechanisms of platelet-derived growth factor action.

Coughlin SR, Escobedo JA, Williams LT.

Prog Clin Biol Res. 1988;266:39-45. Review. No abstract available.

PMID:
2837788

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