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Multiyear Rehospitalization Rates and Hospital Outcomes in an Integrated Health Care System.

Escobar GJ, Plimier C, Greene JD, Liu V, Kipnis P.

JAMA Netw Open. 2019 Dec 2;2(12):e1916769. doi: 10.1001/jamanetworkopen.2019.16769.


Neonatal Sepsis Evaluation: Facing the Certainty of Uncertainty.

Puopolo KM, Escobar GJ.

JAMA Pediatr. 2019 Sep 3. doi: 10.1001/jamapediatrics.2019.2832. [Epub ahead of print] No abstract available.


Effect of donor, component, and recipient characteristics on hemoglobin increments following red blood cell transfusion.

Roubinian NH, Plimier C, Woo JP, Lee C, Bruhn R, Liu VX, Escobar GJ, Kleinman SH, Triulzi DJ, Murphy EL, Busch MP.

Blood. 2019 Sep 26;134(13):1003-1013. doi: 10.1182/blood.2019000773. Epub 2019 Jul 26.


Assessing clinical heterogeneity in sepsis through treatment patterns and machine learning.

Fohner AE, Greene JD, Lawson BL, Chen JH, Kipnis P, Escobar GJ, Liu VX.

J Am Med Inform Assoc. 2019 Dec 1;26(12):1466-1477. doi: 10.1093/jamia/ocz106.


Red blood cell transfusions for emergency department patients with gastrointestinal bleeding within an integrated health system.

Mark DG, Huang J, Plimier C, Reed ME, Escobar GJ, Vinson DR, Roubinian NH.

Am J Emerg Med. 2019 Jun 10. pii: S0735-6757(19)30396-1. doi: 10.1016/j.ajem.2019.06.019. [Epub ahead of print]


Statistical Modeling and Aggregate-Weighted Scoring Systems in Prediction of Mortality and ICU Transfer: A Systematic Review.

Linnen DT, Escobar GJ, Hu X, Scruth E, Liu V, Stephens C.

J Hosp Med. 2019 Mar;14(3):161-169. doi: 10.12788/jhm.3151. Review.


Automated early detection of obstetric complications: theoretic and methodologic considerations.

Escobar GJ, Gupta NR, Walsh EM, Soltesz L, Terry SM, Kipnis P.

Am J Obstet Gynecol. 2019 Apr;220(4):297-307. doi: 10.1016/j.ajog.2019.01.208. Epub 2019 Jan 22.


Prevalence of infant bronchiolitis-coded healthcare encounters attributable to RSV.

Turi KN, Wu P, Escobar GJ, Gebretsadik T, Ding T, Walsh EM, Li SX, Carroll KN, Hartert TV.

Health Sci Rep. 2018 Oct 12;1(12):e91. doi: 10.1002/hsr2.91. eCollection 2018 Dec.


Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study.

Roubinian NH, Murphy EL, Mark DG, Triulzi DJ, Carson JL, Lee C, Kipnis P, Kleinman S, Liu VX, Escobar GJ.

Ann Intern Med. 2019 Jan 15;170(2):81-89. doi: 10.7326/M17-3253. Epub 2018 Dec 18.


Associations of Intensive Care Unit Capacity Strain with Disposition and Outcomes of Patients with Sepsis Presenting to the Emergency Department.

Anesi GL, Liu VX, Gabler NB, Delgado MK, Kohn R, Weissman GE, Bayes B, Escobar GJ, Halpern SD.

Ann Am Thorac Soc. 2018 Nov;15(11):1328-1335. doi: 10.1513/AnnalsATS.201804-241OC.


Risk Adjustment for Hospital Characteristics Reduces Unexplained Hospital Variation in Pressure Injury Risk.

Linnen DT, Kipnis P, Rondinelli J, Greene JD, Liu V, Escobar GJ.

Nurs Res. 2018 Jul/Aug;67(4):314-323. doi: 10.1097/NNR.0000000000000287.


Impact of emergency physician-provided patient education about alternative care venues.

Patel PB, Vinson DR, Gardner MN, Wulf DA, Kipnis P, Liu V, Escobar GJ.

Am J Manag Care. 2018 May;24(5):225-231.


The Impact of Acute Organ Dysfunction on Long-Term Survival in Sepsis.

Schuler A, Wulf DA, Lu Y, Iwashyna TJ, Escobar GJ, Shah NH, Liu VX.

Crit Care Med. 2018 Jun;46(6):843-849. doi: 10.1097/CCM.0000000000003023.


Accuracy of international classification of diseases, ninth revision, codes for postpartum hemorrhage among women undergoing cesarean delivery.

Butwick AJ, Walsh EM, Kuzniewicz M, Li SX, Escobar GJ.

Transfusion. 2018 Apr;58(4):998-1005. doi: 10.1111/trf.14498. Epub 2018 Jan 26.


Effectiveness of Respiratory Syncytial Virus Immunoprophylaxis in Reducing Bronchiolitis Hospitalizations Among High-Risk Infants.

Wu P, Escobar GJ, Gebretsadik T, Carroll KN, Li SX, Walsh EM, Mitchel EF, Sloan C, Dupont WD, Yu C, Horner JR, Hartert TV.

Am J Epidemiol. 2018 Jul 1;187(7):1490-1500. doi: 10.1093/aje/kwy008.


Healthcare Utilization and Infection in the Week Prior to Sepsis Hospitalization.

Liu VX, Escobar GJ, Chaudhary R, Prescott HC.

Crit Care Med. 2018 Apr;46(4):513-516. doi: 10.1097/CCM.0000000000002960.


Hospital-Acquired Pressure Injury: Risk-Adjusted Comparisons in an Integrated Healthcare Delivery System.

Rondinelli J, Zuniga S, Kipnis P, Kawar LN, Liu V, Escobar GJ.

Nurs Res. 2018 Jan/Feb;67(1):16-25. doi: 10.1097/NNR.0000000000000258.


Comparing Hospital Processes and Outcomes in California Medicare Beneficiaries: Simulation Prompts Reconsideration.

Escobar GJ, Baker JM, Turk BJ, Draper D, Liu V, Kipnis P.

Perm J. 2017;21:16-084. doi: 10.7812/TPP/16-084.


Prediction of Recurrent Clostridium Difficile Infection Using Comprehensive Electronic Medical Records in an Integrated Healthcare Delivery System.

Escobar GJ, Baker JM, Kipnis P, Greene JD, Mast TC, Gupta SB, Cossrow N, Mehta V, Liu V, Dubberke ER.

Infect Control Hosp Epidemiol. 2017 Oct;38(10):1196-1203. doi: 10.1017/ice.2017.176. Epub 2017 Aug 24.


Early-Onset Sepsis Calculator-Reply.

Kuzniewicz MW, Escobar GJ, Puopolo KM.

JAMA Pediatr. 2017 Oct 1;171(10):1015-1016. doi: 10.1001/jamapediatrics.2017.2467. No abstract available.


Adaptation of the Acute Organ Failure Score for Use in a Medicare Population.

Courtright KR, Halpern SD, Bayes B, Harhay MO, Raneses E, Kipnis P, Escobar GJ, Kerlin MP.

Crit Care Med. 2017 Nov;45(11):1863-1870. doi: 10.1097/CCM.0000000000002651.


Individual and health system variation in rehospitalizations the year after pneumonia.

Viglianti EM, Prescott HC, Liu V, Escobar GJ, Iwashyna TJ.

Medicine (Baltimore). 2017 Aug;96(31):e7695. doi: 10.1097/MD.0000000000007695.


Identifying Distinct Subgroups of ICU Patients: A Machine Learning Approach.

Vranas KC, Jopling JK, Sweeney TE, Ramsey MC, Milstein AS, Slatore CG, Escobar GJ, Liu VX.

Crit Care Med. 2017 Oct;45(10):1607-1615. doi: 10.1097/CCM.0000000000002548.


Reply: The Timing of Early Antibiotics and Hospital Mortality in Sepsis: Playing Devil's Advocate.

X Liu V, Fielding-Singh V, Iwashyna TJ, Bhattacharya J, Escobar GJ.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):935-936. doi: 10.1164/rccm.201704-0774LE. No abstract available.


The Timing of Early Antibiotics and Hospital Mortality in Sepsis.

Liu VX, Fielding-Singh V, Greene JD, Baker JM, Iwashyna TJ, Bhattacharya J, Escobar GJ.

Am J Respir Crit Care Med. 2017 Oct 1;196(7):856-863. doi: 10.1164/rccm.201609-1848OC.


A Quantitative, Risk-Based Approach to the Management of Neonatal Early-Onset Sepsis.

Kuzniewicz MW, Puopolo KM, Fischer A, Walsh EM, Li S, Newman TB, Kipnis P, Escobar GJ.

JAMA Pediatr. 2017 Apr 1;171(4):365-371. doi: 10.1001/jamapediatrics.2016.4678.


Early detection, prevention, and mitigation of critical illness outside intensive care settings.

Escobar GJ, Dellinger RP.

J Hosp Med. 2016 Nov;11 Suppl 1:S5-S10. doi: 10.1002/jhm.2653.


Early detection of critical illness outside the intensive care unit: Clarifying treatment plans and honoring goals of care using a supportive care team.

Granich R, Sutton Z, Kim YS, Anderson M, Wood H, Scharf JE, Ragins A, Escobar GJ.

J Hosp Med. 2016 Nov;11 Suppl 1:S40-S47. doi: 10.1002/jhm.2660.


Incorporating an Early Detection System Into Routine Clinical Practice in Two Community Hospitals.

Dummett BA, Adams C, Scruth E, Liu V, Guo M, Escobar GJ.

J Hosp Med. 2016 Nov;11 Suppl 1:S25-S31. doi: 10.1002/jhm.2661.


Data that drive: Closing the loop in the learning hospital system.

Liu VX, Morehouse JW, Baker JM, Greene JD, Kipnis P, Escobar GJ.

J Hosp Med. 2016 Nov;11 Suppl 1:S11-S17. doi: 10.1002/jhm.2651.


Implementation of a multicenter performance improvement program for early detection and treatment of severe sepsis in general medical-surgical wards.

Schorr C, Odden A, Evans L, Escobar GJ, Gandhi S, Townsend S, Levy M.

J Hosp Med. 2016 Nov;11 Suppl 1:S32-S39. doi: 10.1002/jhm.2656.


Piloting electronic medical record-based early detection of inpatient deterioration in community hospitals.

Escobar GJ, Turk BJ, Ragins A, Ha J, Hoberman B, LeVine SM, Ballesca MA, Liu V, Kipnis P.

J Hosp Med. 2016 Nov;11 Suppl 1:S18-S24. doi: 10.1002/jhm.2652.


Utilization of Health Services Among Adults With Recurrent Clostridium difficile Infection: A 12-Year Population-Based Study.

Kuntz JL, Baker JM, Kipnis P, Li SX, Liu V, Xie Y, Marcella S, Escobar GJ.

Infect Control Hosp Epidemiol. 2017 Jan;38(1):45-52. doi: 10.1017/ice.2016.232. Epub 2016 Oct 20.


Development and validation of an electronic medical record-based alert score for detection of inpatient deterioration outside the ICU.

Kipnis P, Turk BJ, Wulf DA, LaGuardia JC, Liu V, Churpek MM, Romero-Brufau S, Escobar GJ.

J Biomed Inform. 2016 Dec;64:10-19. doi: 10.1016/j.jbi.2016.09.013. Epub 2016 Sep 20.


Patterns and predictors of severe postpartum anemia after Cesarean section.

Butwick AJ, Walsh EM, Kuzniewicz M, Li SX, Escobar GJ.

Transfusion. 2017 Jan;57(1):36-44. doi: 10.1111/trf.13815. Epub 2016 Sep 13.


Association Among ICU Congestion, ICU Admission Decision, and Patient Outcomes.

Kim SH, Chan CW, Olivares M, Escobar GJ.

Crit Care Med. 2016 Oct;44(10):1814-21. doi: 10.1097/CCM.0000000000001850.


Respiratory syncytial virus immunoprophylaxis in high-risk infants and development of childhood asthma.

Carroll KN, Gebretsadik T, Escobar GJ, Wu P, Li SX, Walsh EM, Mitchel E, Sloan CD, Dupont WD, Hartert TV.

J Allergy Clin Immunol. 2017 Jan;139(1):66-71.e3. doi: 10.1016/j.jaci.2016.01.055. Epub 2016 Apr 21.


Consensus Statement on Electronic Health Predictive Analytics: A Guiding Framework to Address Challenges.

Amarasingham R, Audet AM, Bates DW, Glenn Cohen I, Entwistle M, Escobar GJ, Liu V, Etheredge L, Lo B, Ohno-Machado L, Ram S, Saria S, Schilling LM, Shahi A, Stewart WF, Steyerberg EW, Xie B.

EGEMS (Wash DC). 2016 Mar 7;4(1):1163. doi: 10.13063/2327-9214.1163. eCollection 2016.


The Natural History of Changes in Preferences for Life-Sustaining Treatments and Implications for Inpatient Mortality in Younger and Older Hospitalized Adults.

Kim YS, Escobar GJ, Halpern SD, Greene JD, Kipnis P, Liu V.

J Am Geriatr Soc. 2016 May;64(5):981-9. doi: 10.1111/jgs.14048. Epub 2016 Apr 27.


Development and Implementation of an Early-Onset Sepsis Calculator to Guide Antibiotic Management in Late Preterm and Term Neonates.

Kuzniewicz MW, Walsh EM, Li S, Fischer A, Escobar GJ.

Jt Comm J Qual Patient Saf. 2016 May;42(5):232-9. No abstract available.


Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, Deutschman CS, Escobar GJ, Angus DC.

JAMA. 2016 Feb 23;315(8):762-74. doi: 10.1001/jama.2016.0288. Erratum in: JAMA. 2016 May 24-31;315(20):2237.


Multicenter Implementation of a Treatment Bundle for Patients with Sepsis and Intermediate Lactate Values.

Liu VX, Morehouse JW, Marelich GP, Soule J, Russell T, Skeath M, Adams C, Escobar GJ, Whippy A.

Am J Respir Crit Care Med. 2016 Jun 1;193(11):1264-70. doi: 10.1164/rccm.201507-1489OC.


Evaluation Following Staggered Implementation of the "Rethinking Critical Care" ICU Care Bundle in a Multicenter Community Setting.

Liu V, Herbert D, Foss-Durant A, Marelich GP, Patel A, Whippy A, Turk BJ, Ragins AI, Kipnis P, Escobar GJ.

Crit Care Med. 2016 Mar;44(3):460-7. doi: 10.1097/CCM.0000000000001462.


Nonelective Rehospitalizations and Postdischarge Mortality: Predictive Models Suitable for Use in Real Time.

Escobar GJ, Ragins A, Scheirer P, Liu V, Robles J, Kipnis P.

Med Care. 2015 Nov;53(11):916-23. doi: 10.1097/MLR.0000000000000435.


Why the C-statistic is not informative to evaluate early warning scores and what metrics to use.

Romero-Brufau S, Huddleston JM, Escobar GJ, Liebow M.

Crit Care. 2015 Aug 13;19:285. doi: 10.1186/s13054-015-0999-1.


Lack of improved outcomes with increased use of targeted temperature management following out-of-hospital cardiac arrest: a multicenter retrospective cohort study.

Mark DG, Vinson DR, Hung YY, Anderson ES, Escobar GJ, Carr BG, Abella BS, Ballard DW.

Resuscitation. 2014 Nov;85(11):1549-56. doi: 10.1016/j.resuscitation.2014.08.014. Epub 2014 Aug 30.


Trends in red blood cell transfusion and 30-day mortality among hospitalized patients.

Roubinian NH, Escobar GJ, Liu V, Swain BE, Gardner MN, Kipnis P, Triulzi DJ, Gottschall JL, Wu Y, Carson JL, Kleinman SH, Murphy EL; NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

Transfusion. 2014 Oct;54(10 Pt 2):2678-86. doi: 10.1111/trf.12825. Epub 2014 Aug 18.


Maternal acculturation and the prenatal care experience.

Fuentes-Afflick E, Odouli R, Escobar GJ, Stewart AL, Hessol NA.

J Womens Health (Larchmt). 2014 Aug;23(8):688-706. doi: 10.1089/jwh.2013.4585. Epub 2014 Jun 30.


Decreased red blood cell use and mortality in hospitalized patients.

Roubinian NH, Escobar GJ, Liu V, Gardner MN, Carson JL, Kleinman SH, Murphy EL; NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

JAMA Intern Med. 2014 Aug;174(8):1405-7. doi: 10.1001/jamainternmed.2014.2889. No abstract available.

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