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Items: 1 to 50 of 178

1.

Baseline toxicity and volatility cut-off in reporter gene assays used for high-throughput screening.

Escher BI, Glauch L, König M, Mayer P, Schlichting R.

Chem Res Toxicol. 2019 Jul 17. doi: 10.1021/acs.chemrestox.9b00182. [Epub ahead of print]

PMID:
31313575
2.

Effects of Leachates from UV-Weathered Microplastic in Cell-Based Bioassays.

Rummel CD, Escher BI, Sandblom O, Plassmann MM, Arp HPH, MacLeod M, Jahnke A.

Environ Sci Technol. 2019 Jul 11. doi: 10.1021/acs.est.9b02400. [Epub ahead of print]

PMID:
31257880
3.

Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays.

Henneberger L, Mühlenbrink M, König M, Schlichting R, Fischer FC, Escher BI.

Arch Toxicol. 2019 Jun 22. doi: 10.1007/s00204-019-02498-3. [Epub ahead of print]

PMID:
31230094
4.

Combined Ion-Trapping and Mass Balance Models To Describe the pH-Dependent Uptake and Toxicity of Acidic and Basic Pharmaceuticals in Zebrafish Embryos ( Danio rerio).

Bittner L, Klüver N, Henneberger L, Mühlenbrink M, Zarfl C, Escher BI.

Environ Sci Technol. 2019 Jul 2;53(13):7877-7886. doi: 10.1021/acs.est.9b02563. Epub 2019 Jun 24.

PMID:
31177773
5.

pH-Dependent Uptake and Sublethal Effects of Antihistamines in Zebrafish (Danio rerio) Embryos.

Bittner L, Teixidó E, Keddi I, Escher BI, Klüver N.

Environ Toxicol Chem. 2019 May;38(5):1012-1022. doi: 10.1002/etc.4395. Epub 2019 Apr 9.

PMID:
30779379
6.

Mitochondrial Toxicity of Selected Micropollutants, Their Mixtures, and Surface Water Samples Measured by the Oxygen Consumption Rate in Cells.

Müller ME, Vikstrom S, König M, Schlichting R, Zarfl C, Zwiener C, Escher BI.

Environ Toxicol Chem. 2019 May;38(5):1000-1011. doi: 10.1002/etc.4396. Epub 2019 Apr 5.

PMID:
30779373
7.

Transformation of endocrine disrupting chemicals, pharmaceutical and personal care products during drinking water disinfection.

Leusch FDL, Neale PA, Busetti F, Card M, Humpage A, Orbell JD, Ridgway HF, Stewart MB, van de Merwe JP, Escher BI.

Sci Total Environ. 2019 Mar 20;657:1480-1490. doi: 10.1016/j.scitotenv.2018.12.106. Epub 2018 Dec 11.

PMID:
30677914
8.

An ecotoxicological view on neurotoxicity assessment.

Legradi JB, Di Paolo C, Kraak MHS, van der Geest HG, Schymanski EL, Williams AJ, Dingemans MML, Massei R, Brack W, Cousin X, Begout ML, van der Oost R, Carion A, Suarez-Ulloa V, Silvestre F, Escher BI, Engwall M, Nilén G, Keiter SH, Pollet D, Waldmann P, Kienle C, Werner I, Haigis AC, Knapen D, Vergauwen L, Spehr M, Schulz W, Busch W, Leuthold D, Scholz S, Vom Berg CM, Basu N, Murphy CA, Lampert A, Kuckelkorn J, Grummt T, Hollert H.

Environ Sci Eur. 2018;30(1):46. doi: 10.1186/s12302-018-0173-x. Epub 2018 Dec 14. Review.

9.

C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.

Henneberger L, Mühlenbrink M, Fischer FC, Escher BI.

Chem Res Toxicol. 2019 Jan 22;32(1):168-178. doi: 10.1021/acs.chemrestox.8b00249. Epub 2019 Jan 10.

PMID:
30585484
10.

High-throughput screening and environmental risk assessment: State of the science and emerging applications.

Villeneuve DL, Coady K, Escher BI, Mihaich E, Murphy CA, Schlekat T, Garcia-Reyero N.

Environ Toxicol Chem. 2019 Jan;38(1):12-26. doi: 10.1002/etc.4315. Epub 2018 Dec 20. Review.

PMID:
30570782
11.

QSAR for baseline toxicity and classification of specific modes of action of ionizable organic chemicals in the zebrafish embryo toxicity test.

Klüver N, Bittermann K, Escher BI.

Aquat Toxicol. 2019 Feb;207:110-119. doi: 10.1016/j.aquatox.2018.12.003. Epub 2018 Dec 5.

PMID:
30557756
12.

Emerging investigator series: effect-based characterization of mixtures of environmental pollutants in diverse sediments.

Jahnke A, Sobek A, Bergmann M, Bräunig J, Landmann M, Schäfer S, Escher BI.

Environ Sci Process Impacts. 2018 Dec 12;20(12):1667-1679. doi: 10.1039/c8em00401c.

PMID:
30346461
13.

Application of Experimental Polystyrene Partition Constants and Diffusion Coefficients to Predict the Sorption of Neutral Organic Chemicals to Multiwell Plates in in Vivo and in Vitro Bioassays.

Fischer FC, Cirpka OA, Goss KU, Henneberger L, Escher BI.

Environ Sci Technol. 2018 Nov 20;52(22):13511-13522. doi: 10.1021/acs.est.8b04246. Epub 2018 Oct 31.

PMID:
30298728
14.

Towards a holistic and solution-oriented monitoring of chemical status of European water bodies: how to support the EU strategy for a non-toxic environment?

Brack W, Escher BI, Müller E, Schmitt-Jansen M, Schulze T, Slobodnik J, Hollert H.

Environ Sci Eur. 2018;30(1):33. doi: 10.1186/s12302-018-0161-1. Epub 2018 Sep 4.

15.

Mono(2-ethylhexyl) phthalate (MEHP) and mono(2-ethyl-5-oxohexyl) phthalate (MEOHP) but not di(2-ethylhexyl) phthalate (DEHP) bind productively to the peroxisome proliferator-activated receptor γ.

Kratochvil I, Hofmann T, Rother S, Schlichting R, Moretti R, Scharnweber D, Hintze V, Escher BI, Meiler J, Kalkhof S, von Bergen M.

Rapid Commun Mass Spectrom. 2018 Aug 7. doi: 10.1002/rcm.8258. [Epub ahead of print]

PMID:
30085373
16.

Harvesting the promise of AOPs: An assessment and recommendations.

Carusi A, Davies MR, De Grandis G, Escher BI, Hodges G, Leung KMY, Whelan M, Willett C, Ankley GT.

Sci Total Environ. 2018 Jul 1;628-629:1542-1556. doi: 10.1016/j.scitotenv.2018.02.015. Epub 2018 Feb 22. Review.

17.

What is driving the NF-κB response in environmental water extracts?

Neale PA, Leusch FDL, Escher BI.

Chemosphere. 2018 Nov;210:645-652. doi: 10.1016/j.chemosphere.2018.07.052. Epub 2018 Jul 11.

PMID:
30031348
18.

Combining in vitro reporter gene bioassays with chemical analysis to assess changes in the water quality along the Ammer River, Southwestern Germany.

Müller ME, Escher BI, Schwientek M, Werneburg M, Zarfl C, Zwiener C.

Environ Sci Eur. 2018;30(1):20. doi: 10.1186/s12302-018-0148-y. Epub 2018 Jun 18.

19.

Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy.

Fischer FC, Abele C, Droge STJ, Henneberger L, König M, Schlichting R, Scholz S, Escher BI.

Chem Res Toxicol. 2018 Aug 20;31(8):646-657. doi: 10.1021/acs.chemrestox.8b00019. Epub 2018 Jul 16.

PMID:
29939727
20.

Effect-directed analysis (EDA) of Danube River water sample receiving untreated municipal wastewater from Novi Sad, Serbia.

Hashmi MAK, Escher BI, Krauss M, Teodorovic I, Brack W.

Sci Total Environ. 2018 May 15;624:1072-1081. doi: 10.1016/j.scitotenv.2017.12.187. Epub 2017 Dec 27.

PMID:
29929224
21.

Influence of pH on the uptake and toxicity of β-blockers in embryos of zebrafish, Danio rerio.

Bittner L, Teixido E, Seiwert B, Escher BI, Klüver N.

Aquat Toxicol. 2018 Aug;201:129-137. doi: 10.1016/j.aquatox.2018.05.020. Epub 2018 May 28.

PMID:
29906695
22.

The advantages of linear concentration-response curves for in vitro bioassays with environmental samples.

Escher BI, Neale PA, Villeneuve DL.

Environ Toxicol Chem. 2018 Sep;37(9):2273-2280. doi: 10.1002/etc.4178. Epub 2018 Jul 11.

PMID:
29846006
23.

Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries.

Leusch FDL, Neale PA, Arnal C, Aneck-Hahn NH, Balaguer P, Bruchet A, Escher BI, Esperanza M, Grimaldi M, Leroy G, Scheurer M, Schlichting R, Schriks M, Hebert A.

Water Res. 2018 Aug 1;139:10-18. doi: 10.1016/j.watres.2018.03.056. Epub 2018 Mar 27.

PMID:
29621713
24.

Effect-based monitoring of the Danube River using mobile passive sampling.

Novák J, Vrana B, Rusina T, Okonski K, Grabic R, Neale PA, Escher BI, Macová M, Ait-Aissa S, Creusot N, Allan I, Hilscherová K.

Sci Total Environ. 2018 Sep 15;636:1608-1619. doi: 10.1016/j.scitotenv.2018.02.201. Epub 2018 Mar 10.

PMID:
29530537
25.

Mixture effects in samples of multiple contaminants - An inter-laboratory study with manifold bioassays.

Altenburger R, Scholze M, Busch W, Escher BI, Jakobs G, Krauss M, Krüger J, Neale PA, Ait-Aissa S, Almeida AC, Seiler TB, Brion F, Hilscherová K, Hollert H, Novák J, Schlichting R, Serra H, Shao Y, Tindall A, Tollefsen KE, Umbuzeiro G, Williams TD, Kortenkamp A.

Environ Int. 2018 May;114:95-106. doi: 10.1016/j.envint.2018.02.013. Epub 2018 Feb 28.

26.

Solid-phase extraction as sample preparation of water samples for cell-based and other in vitro bioassays.

Neale PA, Brack W, Aït-Aïssa S, Busch W, Hollender J, Krauss M, Maillot-Maréchal E, Munz NA, Schlichting R, Schulze T, Vogler B, Escher BI.

Environ Sci Process Impacts. 2018 Mar 1;20(3):493-504. doi: 10.1039/c7em00555e. Epub 2018 Mar 1. Review.

PMID:
29493668
27.

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive.

Escher BI, Aїt-Aїssa S, Behnisch PA, Brack W, Brion F, Brouwer A, Buchinger S, Crawford SE, Du Pasquier D, Hamers T, Hettwer K, Hilscherová K, Hollert H, Kase R, Kienle C, Tindall AJ, Tuerk J, van der Oost R, Vermeirssen E, Neale PA.

Sci Total Environ. 2018 Jul 1;628-629:748-765. doi: 10.1016/j.scitotenv.2018.01.340. Epub 2018 Feb 20.

PMID:
29454215
28.

Bioanalytical assessment of adaptive stress responses in drinking water: A predictive tool to differentiate between micropollutants and disinfection by-products.

Hebert A, Feliers C, Lecarpentier C, Neale PA, Schlichting R, Thibert S, Escher BI.

Water Res. 2018 Apr 1;132:340-349. doi: 10.1016/j.watres.2017.12.078. Epub 2018 Jan 3.

PMID:
29353197
29.

Meta-analysis of fish early life stage tests-Association of toxic ratios and acute-to-chronic ratios with modes of action.

Scholz S, Schreiber R, Armitage J, Mayer P, Escher BI, Lidzba A, Léonard M, Altenburger R.

Environ Toxicol Chem. 2018 Apr;37(4):955-969. doi: 10.1002/etc.4090. Epub 2018 Mar 22. Review.

PMID:
29350428
30.

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water.

Neale PA, Altenburger R, Aït-Aïssa S, Brion F, Busch W, de Aragão Umbuzeiro G, Denison MS, Du Pasquier D, Hilscherová K, Hollert H, Morales DA, Novák J, Schlichting R, Seiler TB, Serra H, Shao Y, Tindall AJ, Tollefsen KE, Williams TD, Escher BI.

Water Res. 2017 Oct 15;123:734-750. doi: 10.1016/j.watres.2017.07.016. Epub 2017 Jul 9.

PMID:
28728110
31.

Baseline toxicity and ion-trapping models to describe the pH-dependence of bacterial toxicity of pharmaceuticals.

Baumer A, Bittermann K, Klüver N, Escher BI.

Environ Sci Process Impacts. 2017 Jul 19;19(7):901-916. doi: 10.1039/c7em00099e.

PMID:
28574566
32.

Modeling Exposure in the Tox21 in Vitro Bioassays.

Fischer FC, Henneberger L, König M, Bittermann K, Linden L, Goss KU, Escher BI.

Chem Res Toxicol. 2017 May 15;30(5):1197-1208. doi: 10.1021/acs.chemrestox.7b00023. Epub 2017 Apr 24.

PMID:
28316234
33.

General baseline toxicity QSAR for nonpolar, polar and ionisable chemicals and their mixtures in the bioluminescence inhibition assay with Aliivibrio fischeri.

Escher BI, Baumer A, Bittermann K, Henneberger L, König M, Kühnert C, Klüver N.

Environ Sci Process Impacts. 2017 Mar 22;19(3):414-428. doi: 10.1039/c6em00692b.

PMID:
28197603
34.

Toxic Mixtures in Time-The Sequence Makes the Poison.

Ashauer R, O'Connor I, Escher BI.

Environ Sci Technol. 2017 Mar 7;51(5):3084-3092. doi: 10.1021/acs.est.6b06163. Epub 2017 Feb 17.

35.

Applying mixture toxicity modelling to predict bacterial bioluminescence inhibition by non-specifically acting pharmaceuticals and specifically acting antibiotics.

Neale PA, Leusch FDL, Escher BI.

Chemosphere. 2017 Apr;173:387-394. doi: 10.1016/j.chemosphere.2017.01.018. Epub 2017 Jan 5.

PMID:
28129616
36.

Exploring the oxidative stress response mechanism triggered by environmental water samples.

Neale PA, Achard MES, Escher BI, Leusch FDL.

Environ Sci Process Impacts. 2017 Sep 20;19(9):1126-1133. doi: 10.1039/c6em00541a.

PMID:
28009908
37.

From the exposome to mechanistic understanding of chemical-induced adverse effects.

Escher BI, Hackermüller J, Polte T, Scholz S, Aigner A, Altenburger R, Böhme A, Bopp SK, Brack W, Busch W, Chadeau-Hyam M, Covaci A, Eisenträger A, Galligan JJ, Garcia-Reyero N, Hartung T, Hein M, Herberth G, Jahnke A, Kleinjans J, Klüver N, Krauss M, Lamoree M, Lehmann I, Luckenbach T, Miller GW, Müller A, Phillips DH, Reemtsma T, Rolle-Kampczyk U, Schüürmann G, Schwikowski B, Tan YM, Trump S, Walter-Rohde S, Wambaugh JF.

Environ Int. 2017 Feb;99:97-106. doi: 10.1016/j.envint.2016.11.029. Epub 2016 Dec 8. Review.

38.

Impact of untreated wastewater on a major European river evaluated with a combination of in vitro bioassays and chemical analysis.

König M, Escher BI, Neale PA, Krauss M, Hilscherová K, Novák J, Teodorović I, Schulze T, Seidensticker S, Kamal Hashmi MA, Ahlheim J, Brack W.

Environ Pollut. 2017 Jan;220(Pt B):1220-1230. doi: 10.1016/j.envpol.2016.11.011. Epub 2016 Nov 22.

PMID:
27884472
39.

Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams.

Neale PA, Munz NA, Aїt-Aїssa S, Altenburger R, Brion F, Busch W, Escher BI, Hilscherová K, Kienle C, Novák J, Seiler TB, Shao Y, Stamm C, Hollender J.

Sci Total Environ. 2017 Jan 15;576:785-795. doi: 10.1016/j.scitotenv.2016.10.141. Epub 2016 Oct 29.

PMID:
27810763
40.

Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources.

Brack W, Dulio V, Ågerstrand M, Allan I, Altenburger R, Brinkmann M, Bunke D, Burgess RM, Cousins I, Escher BI, Hernández FJ, Hewitt LM, Hilscherová K, Hollender J, Hollert H, Kase R, Klauer B, Lindim C, Herráez DL, Miège C, Munthe J, O'Toole S, Posthuma L, Rüdel H, Schäfer RB, Sengl M, Smedes F, van de Meent D, van den Brink PJ, van Gils J, van Wezel AP, Vethaak AD, Vermeirssen E, von der Ohe PC, Vrana B.

Sci Total Environ. 2017 Jan 15;576:720-737. doi: 10.1016/j.scitotenv.2016.10.104. Epub 2016 Oct 28.

PMID:
27810758
41.

Including Bioconcentration Kinetics for the Prioritization and Interpretation of Regulatory Aquatic Toxicity Tests of Highly Hydrophobic Chemicals.

Kwon JH, Lee SY, Kang HJ, Mayer P, Escher BI.

Environ Sci Technol. 2016 Nov 1;50(21):12004-12011. Epub 2016 Oct 19.

PMID:
27715022
42.

The 2015 Annual Meeting of SETAC German Language Branch in Zurich (7-10 September, 2015): Ecotoxicology and environmental chemistry-from research to application.

Werner I, Aldrich A, Becker B, Becker D, Brinkmann M, Burkhardt M, Caspers N, Campiche S, Chèvre N, Düring RA, Escher BI, Fischer F, Giebner S, Heye K, Hollert H, Junghans M, Kienle C, Knauer K, Korkaric M, Märkl V, Muncke J, Oehlmann J, Reifferscheid G, Rensch D, Schäffer A, Schiwy S, Schwarz S, Segner H, Simon E, Triebskorn R, Vermeirssen EL, Wintgens T, Zennegg M.

Environ Sci Eur. 2016;28(1):20. Epub 2016 Jul 6. Review.

43.

Pathway-Based Approaches for Environmental Monitoring and Risk Assessment.

Ankley G, Escher BI, Hartung T, Shaw I.

Environ Sci Technol. 2016 Oct 4;50(19):10295-10296. No abstract available.

PMID:
27696862
44.

Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test.

Klüver N, Vogs C, Altenburger R, Escher BI, Scholz S.

Chemosphere. 2016 Dec;164:164-173. doi: 10.1016/j.chemosphere.2016.08.079. Epub 2016 Aug 31.

PMID:
27588575
45.

Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts - Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring.

Di Paolo C, Ottermanns R, Keiter S, Ait-Aissa S, Bluhm K, Brack W, Breitholtz M, Buchinger S, Carere M, Chalon C, Cousin X, Dulio V, Escher BI, Hamers T, Hilscherová K, Jarque S, Jonas A, Maillot-Marechal E, Marneffe Y, Nguyen MT, Pandard P, Schifferli A, Schulze T, Seidensticker S, Seiler TB, Tang J, van der Oost R, Vermeirssen E, Zounková R, Zwart N, Hollert H.

Water Res. 2016 Nov 1;104:473-484. doi: 10.1016/j.watres.2016.08.018. Epub 2016 Aug 12.

PMID:
27585427
46.

Combining Passive Sampling with Toxicological Characterization of Complex Mixtures of Pollutants from the Aquatic Environment.

Jahnke A, Witt G, Schäfer S, Haase N, Escher BI.

Adv Biochem Eng Biotechnol. 2017;157:225-261. doi: 10.1007/10_2015_5014. Review.

PMID:
27488201
47.

Bioanalytical effect-balance model to determine the bioavailability of organic contaminants in sediments affected by black and natural carbon.

Bräunig J, Tang JYM, Warne MSJ, Escher BI.

Chemosphere. 2016 Aug;156:181-190. doi: 10.1016/j.chemosphere.2016.04.056. Epub 2016 May 10.

PMID:
27176940
48.

Sample Enrichment for Bioanalytical Assessment of Disinfected Drinking Water: Concentrating the Polar, the Volatiles, and the Unknowns.

Stalter D, Peters LI, O'Malley E, Tang JY, Revalor M, Farré MJ, Watson K, von Gunten U, Escher BI.

Environ Sci Technol. 2016 Jun 21;50(12):6495-505. doi: 10.1021/acs.est.6b00712. Epub 2016 Jun 1.

PMID:
27153244
49.

Solubility enhancement of dioxins and PCBs by surfactant monomers and micelles quantified with polymer depletion techniques.

Schacht VJ, Grant SC, Escher BI, Hawker DW, Gaus C.

Chemosphere. 2016 Jun;152:99-106. doi: 10.1016/j.chemosphere.2016.02.122. Epub 2016 Mar 8.

PMID:
26966808
50.

Experimental Solubility Approach to Determine PDMS-Water Partition Constants and PDMS Activity Coefficients.

Grant S, Schacht VJ, Escher BI, Hawker DW, Gaus C.

Environ Sci Technol. 2016 Mar 15;50(6):3047-54. doi: 10.1021/acs.est.5b04655. Epub 2016 Mar 2.

PMID:
26881312

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