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Items: 11

1.

A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.

Saunders LR, Bankovich AJ, Anderson WC, Aujay MA, Bheddah S, Black K, Desai R, Escarpe PA, Hampl J, Laysang A, Liu D, Lopez-Molina J, Milton M, Park A, Pysz MA, Shao H, Slingerland B, Torgov M, Williams SA, Foord O, Howard P, Jassem J, Badzio A, Czapiewski P, Harpole DH, Dowlati A, Massion PP, Travis WD, Pietanza MC, Poirier JT, Rudin CM, Stull RA, Dylla SJ.

Sci Transl Med. 2015 Aug 26;7(302):302ra136. doi: 10.1126/scitranslmed.aac9459.

2.
3.

Vaccine-induced antibodies to the native, oligomeric envelope glycoproteins of primary HIV-1 isolates.

Lee SA, Orque R, Escarpe PA, Peterson ML, Good JW, Zaharias EM, Berman PW, Sheppard HW, Shibata R.

Vaccine. 2001 Nov 12;20(3-4):563-76.

PMID:
11672923
4.

Carbocyclic influenza neuraminidase inhibitors possessing a C3-cyclic amine side chain: synthesis and inhibitory activity.

Lew W, Wu H, Chen X, Graves BJ, Escarpe PA, MacArthur HL, Mendel DB, Kim CU.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1257-60.

PMID:
10866394
5.

Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity.

Lew W, Escarpe PA, Mendel DB, Sweeny DJ, Kim CU.

Bioorg Med Chem Lett. 1999 Oct 4;9(19):2811-4.

PMID:
10522696
6.

Synthesis and evaluation of 1,4,5,6-tetrahydropyridazine derivatives as influenza neuraminidase inhibitors.

Zhang L, Williams MA, Mendel DB, Escarpe PA, Chen X, Wang KY, Graves BJ, Lawton G, Kim CU.

Bioorg Med Chem Lett. 1999 Jul 5;9(13):1751-6.

PMID:
10406636
7.

A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity.

Lew W, Wu H, Mendel DB, Escarpe PA, Chen X, Laver WG, Graves BJ, Kim CU.

Bioorg Med Chem Lett. 1998 Dec 1;8(23):3321-4.

PMID:
9873727
8.

Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS 4071.

Tai CY, Escarpe PA, Sidwell RW, Williams MA, Lew W, Wu H, Kim CU, Mendel DB.

Antimicrob Agents Chemother. 1998 Dec;42(12):3234-41.

9.

Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors.

Kim CU, Lew W, Williams MA, Wu H, Zhang L, Chen X, Escarpe PA, Mendel DB, Laver WG, Stevens RC.

J Med Chem. 1998 Jul 2;41(14):2451-60.

PMID:
9651151
10.

Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071.

Li W, Escarpe PA, Eisenberg EJ, Cundy KC, Sweet C, Jakeman KJ, Merson J, Lew W, Williams M, Zhang L, Kim CU, Bischofberger N, Chen MS, Mendel DB.

Antimicrob Agents Chemother. 1998 Mar;42(3):647-53.

11.

Oral administration of a prodrug of the influenza virus neuraminidase inhibitor GS 4071 protects mice and ferrets against influenza infection.

Mendel DB, Tai CY, Escarpe PA, Li W, Sidwell RW, Huffman JH, Sweet C, Jakeman KJ, Merson J, Lacy SA, Lew W, Williams MA, Zhang L, Chen MS, Bischofberger N, Kim CU.

Antimicrob Agents Chemother. 1998 Mar;42(3):640-6.

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