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Items: 45

1.

Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization.

Su M, Erwin AL, Campbell AM, Pyburn TM, Salay LE, Hanks JL, Lacy DB, Akey DL, Cover TL, Ohi MD.

J Mol Biol. 2019 May 3;431(10):1956-1965. doi: 10.1016/j.jmb.2019.03.029. Epub 2019 Apr 5.

PMID:
30954575
2.

Identification and characterization of 40 novel hydroxymethylbilane synthase mutations that cause acute intermittent porphyria.

Chen B, Solis-Villa C, Erwin AL, Balwani M, Nazarenko I, Phillips JD, Desnick RJ, Yasuda M.

J Inherit Metab Dis. 2019 Jan;42(1):186-194. doi: 10.1002/jimd.12040.

PMID:
30740734
3.

Congenital erythropoietic porphyria: Recent advances.

Erwin AL, Desnick RJ.

Mol Genet Metab. 2018 Dec 27. pii: S1096-7192(18)30647-4. doi: 10.1016/j.ymgme.2018.12.008. [Epub ahead of print] Review.

PMID:
30685241
4.

De novo missense variants in MEIS2 recapitulate the microdeletion phenotype of cardiac and palate abnormalities, developmental delay, intellectual disability and dysmorphic features.

Douglas G, Cho MT, Telegrafi A, Winter S, Carmichael J, Zackai EH, Deardorff MA, Harr M, Williams L, Psychogios A, Erwin AL, Grebe T, Retterer K, Juusola J.

Am J Med Genet A. 2018 Sep;176(9):1845-1851. doi: 10.1002/ajmg.a.40368. Epub 2018 Jul 28.

PMID:
30055086
5.

Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters.

Norris SR, Jung S, Singh P, Strothman CE, Erwin AL, Ohi MD, Zanic M, Ohi R.

Nat Commun. 2018 Jul 9;9(1):2659. doi: 10.1038/s41467-018-04991-2.

6.

Evaluating LC-MS/MS To Measure Accumulation of Compounds within Bacteria.

Iyer R, Ye Z, Ferrari A, Duncan L, Tanudra MA, Tsao H, Wang T, Gao H, Brummel CL, Erwin AL.

ACS Infect Dis. 2018 Sep 14;4(9):1336-1345. doi: 10.1021/acsinfecdis.8b00083. Epub 2018 Jul 13.

PMID:
29961312
7.

The role of sebelipase alfa in the treatment of lysosomal acid lipase deficiency.

Erwin AL.

Therap Adv Gastroenterol. 2017 Jul;10(7):553-562. doi: 10.1177/1756283X17705775. Epub 2017 Apr 26. Review.

8.

While the revolution will not be crystallized, biochemistry reigns supreme.

Takizawa Y, Binshtein E, Erwin AL, Pyburn TM, Mittendorf KF, Ohi MD.

Protein Sci. 2017 Jan;26(1):69-81. doi: 10.1002/pro.3054. Epub 2016 Oct 6. Review.

9.

Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.

Erwin AL.

Cold Spring Harb Perspect Med. 2016 Jul 1;6(7). pii: a025304. doi: 10.1101/cshperspect.a025304. Review.

10.

Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network.

Gallego CJ, Burt A, Sundaresan AS, Ye Z, Shaw C, Crosslin DR, Crane PK, Fullerton SM, Hansen K, Carrell D, Kuivaniemi H, Derr K, de Andrade M, McCarty CA, Kitchner TE, Ragon BK, Stallings SC, Papa G, Bochenek J, Smith ME, Aufox SA, Pacheco JA, Patel V, Friesema EM, Erwin AL, Gottesman O, Gerhard GS, Ritchie M, Motulsky AG, Kullo IJ, Larson EB, Tromp G, Brilliant MH, Bottinger E, Denny JC, Roden DM, Williams MS, Jarvik GP.

Am J Hum Genet. 2015 Oct 1;97(4):512-20. doi: 10.1016/j.ajhg.2015.08.008. Epub 2015 Sep 10.

11.

Cordon bleu promotes the assembly of brush border microvilli.

Grega-Larson NE, Crawley SW, Erwin AL, Tyska MJ.

Mol Biol Cell. 2015 Nov 1;26(21):3803-15. doi: 10.1091/mbc.E15-06-0443. Epub 2015 Sep 9.

12.

Direct measurement of efflux in Pseudomonas aeruginosa using an environment-sensitive fluorescent dye.

Iyer R, Erwin AL.

Res Microbiol. 2015 Jul-Aug;166(6):516-24. doi: 10.1016/j.resmic.2015.06.006. Epub 2015 Jun 25.

PMID:
26117599
13.

Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver.

Yasuda M, Erwin AL, Liu LU, Balwani M, Chen B, Kadirvel S, Gan L, Fiel MI, Gordon RE, Yu C, Clavero S, Arvelakis A, Naik H, Martin LD, Phillips JD, Anderson KE, Sadagoparamanujam VM, Florman SS, Desnick RJ.

Mol Med. 2015 Jun 5;21:487-95. doi: 10.2119/molmed.2015.00099.

14.

A fluorescent microplate assay quantifies bacterial efflux and demonstrates two distinct compound binding sites in AcrB.

Iyer R, Ferrari A, Rijnbrand R, Erwin AL.

Antimicrob Agents Chemother. 2015 Apr;59(4):2388-97. doi: 10.1128/AAC.05112-14. Epub 2015 Feb 2.

15.

Physician Attitudes toward Adopting Genome-Guided Prescribing through Clinical Decision Support.

Overby CL, Erwin AL, Abul-Husn NS, Ellis SB, Scott SA, Obeng AO, Kannry JL, Hripcsak G, Bottinger EP, Gottesman O.

J Pers Med. 2014 Feb 27;4(1):35-49. doi: 10.3390/jpm4010035.

16.

Analysis of genetic relatedness of Haemophilus influenzae isolates by multilocus sequence typing.

Erwin AL, Sandstedt SA, Bonthuis PJ, Geelhood JL, Nelson KL, Unrath WC, Diggle MA, Theodore MJ, Pleatman CR, Mothershed EA, Sacchi CT, Mayer LW, Gilsdorf JR, Smith AL.

J Bacteriol. 2008 Feb;190(4):1473-83. Epub 2007 Dec 7.

17.

Haemophilus influenzae phasevarions have evolved from type III DNA restriction systems into epigenetic regulators of gene expression.

Fox KL, Dowideit SJ, Erwin AL, Srikhanta YN, Smith AL, Jennings MP.

Nucleic Acids Res. 2007;35(15):5242-52. Epub 2007 Aug 2.

18.

Nontypeable Haemophilus influenzae: understanding virulence and commensal behavior.

Erwin AL, Smith AL.

Trends Microbiol. 2007 Aug;15(8):355-62. Epub 2007 Jun 27. Review.

PMID:
17600718
19.

Chloramphenicol is a substrate for a novel nitroreductase pathway in Haemophilus influenzae.

Smith AL, Erwin AL, Kline T, Unrath WC, Nelson K, Weber A, Howald WN.

Antimicrob Agents Chemother. 2007 Aug;51(8):2820-9. Epub 2007 May 25.

20.

Role of lgtC in resistance of nontypeable Haemophilus influenzae strain R2866 to human serum.

Erwin AL, Allen S, Ho DK, Bonthuis PJ, Jarisch J, Nelson KL, Tsao DL, Unrath WC, Watson ME Jr, Gibson BW, Apicella MA, Smith AL.

Infect Immun. 2006 Nov;74(11):6226-35. Epub 2006 Sep 11. Erratum in: Infect Immun. 2006 Dec;74(12):7047. Bonthius, Paul J [corrected to Bonthuis, Paul J].

21.

Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa.

Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK.

Antimicrob Agents Chemother. 2006 Jun;50(6):2178-84.

22.

Heterogeneity in tandem octanucleotides within Haemophilus influenzae lipopolysaccharide biosynthetic gene losA affects serum resistance.

Erwin AL, Bonthuis PJ, Geelhood JL, Nelson KL, McCrea KW, Gilsdorf JR, Smith AL.

Infect Immun. 2006 Jun;74(6):3408-14.

23.

Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae.

Erwin AL, Nelson KL, Mhlanga-Mutangadura T, Bonthuis PJ, Geelhood JL, Morlin G, Unrath WC, Campos J, Crook DW, Farley MM, Henderson FW, Jacobs RF, Mühlemann K, Satola SW, van Alphen L, Golomb M, Smith AL.

Infect Immun. 2005 Sep;73(9):5853-63.

24.

Peptides selected for binding to a virulent strain of Haemophilus influenzae by phage display are bactericidal.

Bishop-Hurley SL, Schmidt FJ, Erwin AL, Smith AL.

Antimicrob Agents Chemother. 2005 Jul;49(7):2972-8.

25.
26.

Potent, novel in vitro inhibitors of the Pseudomonas aeruginosa deacetylase LpxC.

Kline T, Andersen NH, Harwood EA, Bowman J, Malanda A, Endsley S, Erwin AL, Doyle M, Fong S, Harris AL, Mendelsohn B, Mdluli K, Raetz CR, Stover CK, Witte PR, Yabannavar A, Zhu S.

J Med Chem. 2002 Jul 4;45(14):3112-29.

PMID:
12086497
27.

Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection.

Wizemann TM, Heinrichs JH, Adamou JE, Erwin AL, Kunsch C, Choi GH, Barash SC, Rosen CA, Masure HR, Tuomanen E, Gayle A, Brewah YA, Walsh W, Barren P, Lathigra R, Hanson M, Langermann S, Johnson S, Koenig S.

Infect Immun. 2001 Mar;69(3):1593-8.

28.

Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis.

Adamou JE, Heinrichs JH, Erwin AL, Walsh W, Gayle T, Dormitzer M, Dagan R, Brewah YA, Barren P, Lathigra R, Langermann S, Koenig S, Johnson S.

Infect Immun. 2001 Feb;69(2):949-58.

29.

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.

Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV.

Nature. 2000 Aug 31;406(6799):959-64.

PMID:
10984043
30.

Role of lipopolysaccharide phase variation in susceptibility of Haemophilus influenzae to bactericidal immunoglobulin M antibodies in rabbit sera.

Erwin AL, Brewah YA, Couchenour DA, Barren PR, Burke SJ, Choi GH, Lathigra R, Hanson MS, Weiser JN.

Infect Immun. 2000 May;68(5):2804-7.

33.

Identification and characterization of auxotrophs of Neisseria meningitidis produced by Tn916 mutagenesis.

Erwin AL, Stephens DS.

FEMS Microbiol Lett. 1995 Apr 1;127(3):223-8.

PMID:
7758936
34.

Use of antibiotics to select auxotrophic mutants of Neisseria meningitidis.

Erwin AL, Gill MJ, Gotschlich EC.

Microb Pathog. 1995 Apr;18(4):289-96.

PMID:
7476094
36.

Eukaryotic lipopolysaccharide deacylating enzyme.

Munford RS, Erwin AL.

Methods Enzymol. 1992;209:485-92. No abstract available.

PMID:
1495428
38.
39.

Deacylation of structurally diverse lipopolysaccharides by human acyloxyacyl hydrolase.

Erwin AL, Munford RS.

J Biol Chem. 1990 Sep 25;265(27):16444-9.

40.

Major integral membrane protein immunogens of Treponema pallidum are proteolipids.

Chamberlain NR, Brandt ME, Erwin AL, Radolf JD, Norgard MV.

Infect Immun. 1989 Sep;57(9):2872-7.

42.

Potential virulence-associated factors in Brazilian purpuric fever. Brazilian Purpuric Fever Study Group.

Carlone GM, Gorelkin L, Gheesling LL, Erwin AL, Hoiseth SK, Mulks MH, O'Connor SP, Weyant RS, Myrick J, Rubin L, et al.

J Clin Microbiol. 1989 Apr;27(4):609-14. Review. No abstract available.

43.

Human antibody response to outer membrane proteins and fimbriae of Haemophilus influenzae type b.

Erwin AL, Kenny GE, Smith AL, Stull TL.

Can J Microbiol. 1988 Jun;34(6):723-9.

PMID:
2904834
44.

Haemophilus influenzae type b lipooligosaccharide induces meningeal inflammation.

Syrogiannopoulos GA, Hansen EJ, Erwin AL, Munford RS, Rutledge J, Reisch JS, McCracken GH Jr.

J Infect Dis. 1988 Feb;157(2):237-44.

PMID:
3257246
45.

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