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Evidence of evolutionary history and selective sweeps in the genome of Meishan pig reveals its genetic and phenotypic characterization.

Zhao P, Yu Y, Feng W, Du H, Yu J, Kang H, Zheng X, Wang Z, Liu GE, Ernst CW, Ran X, Wang J, Liu JF.

Gigascience. 2018 May 1;7(5). doi: 10.1093/gigascience/giy058.


Characterization of efficacy and safety of pathogen inactivated and quarantine plasma in routine use for treatment of acquired immune thrombotic thrombocytopenic purpura.

Herbrecht R, Ojeda-Uribe M, Kientz D, Fohrer C, Bohbot A, Hinschberger O, Liu KL, Remy E, Ernst C, Lin JS, Corash L, Cazenave JP.

Vox Sang. 2018 May 21. doi: 10.1111/vox.12663. [Epub ahead of print]


Association of the Preoperative Body Mass Index With Postoperative Complications After Treatment of Oral Squamous Cell Carcinoma.

Wolfer S, Foos T, Kunzler A, Ernst C, Schultze-Mosgau S.

J Oral Maxillofac Surg. 2018 Mar 8. pii: S0278-2391(18)30193-9. doi: 10.1016/j.joms.2018.02.029. [Epub ahead of print]


Lowered dose full-spine radiography in pediatric patients with idiopathic scoliosis.

Ernst C, Buls N, Laumen A, Van Gompel G, Verhelle F, de Mey J.

Eur Spine J. 2018 May;27(5):1089-1095. doi: 10.1007/s00586-018-5561-9. Epub 2018 Mar 27.


Performance of in silico prediction tools for the classification of rare BRCA1/2 missense variants in clinical diagnostics.

Ernst C, Hahnen E, Engel C, Nothnagel M, Weber J, Schmutzler RK, Hauke J.

BMC Med Genomics. 2018 Mar 27;11(1):35. doi: 10.1186/s12920-018-0353-y.


Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):791. doi: 10.1038/mp.2018.5. No abstract available.


Pharmacotherapy for Perinatal Depression.

Lusskin SI, Khan SJ, Ernst C, Habib S, Fersh ME, Albertini ES.

Clin Obstet Gynecol. 2018 Mar 20. doi: 10.1097/GRF.0000000000000365. [Epub ahead of print]


Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer.

Hauke J, Horvath J, Groß E, Gehrig A, Honisch E, Hackmann K, Schmidt G, Arnold N, Faust U, Sutter C, Hentschel J, Wang-Gohrke S, Smogavec M, Weber BHF, Weber-Lassalle N, Weber-Lassalle K, Borde J, Ernst C, Altmüller J, Volk AE, Thiele H, Hübbel V, Nürnberg P, Keupp K, Versmold B, Pohl E, Kubisch C, Grill S, Paul V, Herold N, Lichey N, Rhiem K, Ditsch N, Ruckert C, Wappenschmidt B, Auber B, Rump A, Niederacher D, Haaf T, Ramser J, Dworniczak B, Engel C, Meindl A, Schmutzler RK, Hahnen E.

Cancer Med. 2018 Apr;7(4):1349-1358. doi: 10.1002/cam4.1376. Epub 2018 Mar 9.


Red blood cells treated with the amustaline (S-303) pathogen reduction system: a transfusion study in cardiac surgery.

Brixner V, Kiessling AH, Madlener K, Müller MM, Leibacher J, Dombos S, Weber I, Pfeiffer HU, Geisen C, Schmidt M, Henschler R, North A, Huang N, Mufti N, Erickson A, Ernst C, Rico S, Benjamin RJ, Corash LM, Seifried E.

Transfusion. 2018 Apr;58(4):905-916. doi: 10.1111/trf.14528. Epub 2018 Mar 1.


Visible Light Curing Devices - Irradiance and Use in 302 German Dental Offices.

Ernst CP, Price RB, Callaway A, Masek A, Schwarm H, Rullmann I, Willershausen B, Ehlers V.

J Adhes Dent. 2018;20(1):41-55. doi: 10.3290/j.jad.a39881.


Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species.

Lowe R, Barton C, Jenkins CA, Ernst C, Forman O, Fernandez-Twinn DS, Bock C, Rossiter SJ, Faulkes CG, Ozanne SE, Walter L, Odom DT, Mellersh C, Rakyan VK.

Genome Biol. 2018 Feb 16;19(1):22. doi: 10.1186/s13059-018-1397-1.


[Surgical treatment of lumbar disc herniation].

Støttrup C, Andresen AK, Ernst C, Andersen MØ.

Ugeskr Laeger. 2018 Jan 22;180(2). pii: V05170398. Danish.


BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.

Weber-Lassalle N, Hauke J, Ramser J, Richters L, Groß E, Blümcke B, Gehrig A, Kahlert AK, Müller CR, Hackmann K, Honisch E, Weber-Lassalle K, Niederacher D, Borde J, Thiele H, Ernst C, Altmüller J, Neidhardt G, Nürnberg P, Klaschik K, Schroeder C, Platzer K, Volk AE, Wang-Gohrke S, Just W, Auber B, Kubisch C, Schmidt G, Horvath J, Wappenschmidt B, Engel C, Arnold N, Dworniczak B, Rhiem K, Meindl A, Schmutzler RK, Hahnen E.

Breast Cancer Res. 2018 Jan 24;20(1):7. doi: 10.1186/s13058-018-0935-9.


How to make a tumour: cell type specific dissection of Ustilago maydis-induced tumour development in maize leaves.

Matei A, Ernst C, Günl M, Thiele B, Altmüller J, Walbot V, Usadel B, Doehlemann G.

New Phytol. 2018 Mar;217(4):1681-1695. doi: 10.1111/nph.14960. Epub 2018 Jan 4.


Attitudes Toward e-Health: The Otolaryngologists' Point of View.

Holderried M, Hoeper A, Holderried F, Blumenstock G, Ernst C, Tropitzsch A.

Telemed J E Health. 2018 Jun;24(6):425-432. doi: 10.1089/tmj.2017.0158. Epub 2017 Dec 11.


Pharmacokinetics of Diclofenac and Hydroxypropyl-β-Cyclodextrin (HPβCD) Following Administration of Injectable HPβCD-Diclofenac in Subjects With Mild to Moderate Renal Insufficiency or Mild Hepatic Impairment.

Hamilton DA, Ernst CC, Kramer WG, Madden D, Lang E, Liao E, Lacouture PG, Ramaiya A, Carr DB.

Clin Pharmacol Drug Dev. 2018 Feb;7(2):110-122. doi: 10.1002/cpdd.417. Epub 2017 Dec 2.


The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity.

Ernst C, Odom DT, Kutter C.

Nat Commun. 2017 Nov 10;8(1):1411. doi: 10.1038/s41467-017-01049-7. Review.


Estimation of genetic parameters for lesion scores and growth traits in group-housed pigs.

Wurtz KE, Siegford JM, Bates RO, Ernst CW, Steibel JP.

J Anim Sci. 2017 Oct;95(10):4310-4317. doi: 10.2527/jas2017.1757.


Strategies to Advance Drug Discovery in Rare Monogenic Intellectual Disability Syndromes.

Hettige NC, Manzano-Vargas K, Jefri M, Ernst C.

Int J Neuropsychopharmacol. 2018 Mar 1;21(3):201-206. doi: 10.1093/ijnp/pyx090.


Imaging Mercury's Polar Deposits during MESSENGER's Low-altitude Campaign.

Chabot NL, Ernst CM, Paige DA, Nair H, Denevi BW, Blewett DT, Murchie SL, Deutsch AN, Head JW, Solomon SC.

Geophys Res Lett. 2016 Sep 28;43(18):9461-9468. doi: 10.1002/2016GL070403. Epub 2016 Sep 17.


The quantitative link of lung clearance index to bronchial segments affected by bronchiectasis.

Verbanck S, King GG, Zhou W, Miller A, Thamrin C, Schuermans D, Ilsen B, Ernst CW, de Mey J, Vincken W, Vanderhelst E.

Thorax. 2018 Jan;73(1):82-84. doi: 10.1136/thoraxjnl-2017-210496. Epub 2017 Sep 2.


Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence.

Lutz PE, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D, Chay MA, Yang J, Larivière V, M'Boutchou MN, van Kempen LC, Yerko V, Prud'homme J, Davoli MA, Vaillancourt K, Théroux JF, Bramoullé A, Zhang TY, Meaney MJ, Ernst C, Côté D, Mechawar N, Turecki G.

Am J Psychiatry. 2017 Dec 1;174(12):1185-1194. doi: 10.1176/appi.ajp.2017.16111286. Epub 2017 Jul 28.


Profiling and characterization of a longissimus dorsi muscle microRNA dataset from an F2 Duroc × Pietrain pig resource population.

Daza KR, Steibel JP, Velez-Irizarry D, Raney NE, Bates RO, Ernst CW.

Genom Data. 2017 Jul 5;13:50-53. doi: 10.1016/j.gdata.2017.07.006. eCollection 2017 Sep.


Return to work after lumbar disc surgery is related to the length of preoperative sick leave.

Andersen MØ, Ernst C, Rasmussen J, Dahl S, Carreon LY.

Dan Med J. 2017 Jul;64(7). pii: A5392.


DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects.

Vaillancourt K, Ernst C, Mash D, Turecki G.

Genes (Basel). 2017 May 12;8(5). pii: E138. doi: 10.3390/genes8050138. Review.


Evidence for transcriptome-wide RNA editing among Sus scrofa PRE-1 SINE elements.

Funkhouser SA, Steibel JP, Bates RO, Raney NE, Schenk D, Ernst CW.

BMC Genomics. 2017 May 9;18(1):360. doi: 10.1186/s12864-017-3766-7.


The potential of eHealth in otorhinolaryngology-head and neck surgery: patients' perspectives.

Holderried M, Ernst C, Holderried F, Rieger M, Blumenstock G, Tropitzsch A.

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2933-2943. doi: 10.1007/s00405-017-4567-y. Epub 2017 Apr 25.


MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):1051-1065. doi: 10.1038/mp.2017.86. Epub 2017 Apr 25.


Genome-wide association study in an F2 Duroc x Pietrain resource population for economically important meat quality and carcass traits.

Casiró S, Velez-Irizarry D, Ernst CW, Raney NE, Bates RO, Charles MG, Steibel JP.

J Anim Sci. 2017 Feb;95(2):545-558. doi: 10.2527/jas.2016.1003.


Patient-reported Outcomes and Revision Rates at a Mean Follow-up of 10 Years After Lumbar Total Disc Replacement.

Laugesen LA, Paulsen RT, Carreon L, Ernst C, Andersen MØ.

Spine (Phila Pa 1976). 2017 Nov 1;42(21):1657-1663. doi: 10.1097/BRS.0000000000002174.


A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing.

Bell S, Peng H, Crapper L, Kolobova I, Maussion G, Vasuta C, Yerko V, Wong TP, Ernst C.

Stem Cells Transl Med. 2017 Mar;6(3):886-896. doi: 10.1002/sctm.16-0158. Epub 2016 Dec 1.


Potential molecular consequences of transgene integration: The R6/2 mouse example.

Jacobsen JC, Erdin S, Chiang C, Hanscom C, Handley RR, Barker DD, Stortchevoi A, Blumenthal I, Reid SJ, Snell RG, MacDonald ME, Morton AJ, Ernst C, Gusella JF, Talkowski ME.

Sci Rep. 2017 Jan 25;7:41120. doi: 10.1038/srep41120.


Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.

Chen GG, Gross JA, Lutz PE, Vaillancourt K, Maussion G, Bramoulle A, Théroux JF, Gardini ES, Ehlert U, Bourret G, Masurel A, Lepage P, Mechawar N, Turecki G, Ernst C.

BMC Genomics. 2017 Jan 18;18(1):96. doi: 10.1186/s12864-017-3489-9.


Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.

Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA, Wortman JR, Murphy CI, Hanage WP.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1135-1140. doi: 10.1073/pnas.1616248114. Epub 2017 Jan 17.


Commissioning Monte Carlo algorithm for robotic radiosurgery using cylindrical 3D-array with variable density inserts.

Dechambre D, Baart V, Cucchiaro S, Ernst C, Jansen N, Berkovic P, Mievis C, Coucke P, Gulyban A.

Phys Med. 2017 Jan;33:152-158. doi: 10.1016/j.ejmp.2017.01.005. Epub 2017 Jan 11.


Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer.

Neidhardt G, Hauke J, Ramser J, Groß E, Gehrig A, Müller CR, Kahlert AK, Hackmann K, Honisch E, Niederacher D, Heilmann-Heimbach S, Franke A, Lieb W, Thiele H, Altmüller J, Nürnberg P, Klaschik K, Ernst C, Ditsch N, Jessen F, Ramirez A, Wappenschmidt B, Engel C, Rhiem K, Meindl A, Schmutzler RK, Hahnen E.

JAMA Oncol. 2017 Sep 1;3(9):1245-1248. doi: 10.1001/jamaoncol.2016.5592.


Lesch-Nyhan Syndrome: Models, Theories, and Therapies.

Bell S, Kolobova I, Crapper L, Ernst C.

Mol Syndromol. 2016 Nov;7(6):302-311. Epub 2016 Sep 24. Review.


Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis.

Ernst C, Pike J, Aitken SJ, Long HK, Eling N, Stojic L, Ward MC, Connor F, Rayner TF, Lukk M, Klose RJ, Kutter C, Odom DT.

Elife. 2016 Nov 18;5. pii: e20235. doi: 10.7554/eLife.20235.


Implication of LRRC4C and DPP6 in neurodevelopmental disorders.

Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O'Dushlaine C, McCarroll S, Alda M, Jacquemont S, Ordulu Z, Marshall CR, Carter MT, Shaffer LG, Sklar P, Girirajan S, Morton CC, Gusella JF, Turecki G, Stavropoulos DJ, Sullivan PF, Scherer SW, Talkowski ME, Ernst C.

Am J Med Genet A. 2017 Feb;173(2):395-406. doi: 10.1002/ajmg.a.38021. Epub 2016 Oct 19.


[Lumbar spinal stenosis].

Andresen AK, Ernst C, Andersen MØ.

Ugeskr Laeger. 2016 Oct 10;178(41). pii: V04160245. Danish.


Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma.

Goeppert B, Ernst C, Baer C, Roessler S, Renner M, Mehrabi A, Hafezi M, Pathil A, Warth A, Stenzinger A, Weichert W, Bähr M, Will R, Schirmacher P, Plass C, Weichenhan D.

Epigenetics. 2016 Nov;11(11):780-790. Epub 2016 Sep 3.


Estimates of the actual relationship between half-sibs in a pig population.

García-Baccino CA, Munilla S, Legarra A, Vitezica ZG, Forneris NS, Bates RO, Ernst CW, Raney NE, Steibel JP, Cantet RJ.

J Anim Breed Genet. 2017 Apr;134(2):109-118. doi: 10.1111/jbg.12236. Epub 2016 Sep 26.


Core Concepts Involving Adverse Psychotropic Drug Effects: Assessment, Implications, and Management.

Goldberg JF, Ernst CL.

Psychiatr Clin North Am. 2016 Sep;39(3):375-89. doi: 10.1016/j.psc.2016.04.001. Epub 2016 Jun 24. Review.


Compliance of Clinical Pathways in Elective Laparoscopic Cholecystectomy: Evaluation of Different Implementation Methods.

Holderried M, Hummel R, Falch C, Kirschniak A, Koenigsrainer A, Ernst C, Muller S.

World J Surg. 2016 Dec;40(12):2888-2891. doi: 10.1007/s00268-016-3645-4.


Comparison of areas in shadow from imaging and altimetry in the north polar region of Mercury and implications for polar ice deposits.

Deutsch AN, Chabot NL, Mazarico E, Ernst CM, Head JW, Neumann GA, Solomon SC.

Icarus. 2016 Jun;280:158-171. doi: 10.1016/j.icarus.2016.06.015. Epub 2016 Jun 25.


Refining genomewide association for growth and fat deposition traits in an F pig population.

Duarte JL, Cantet RJ, Rubio YL, Bates RO, Ernst CW, Raney NE, Rogberg-Muñoz A, Steibel JP.

J Anim Sci. 2016 Apr;94(4):1387-97. doi: 10.2527/jas.2015-0182.


A comparison of methods to estimate genomic relationships using pedigree and markers in livestock populations.

Forneris NS, Steibel JP, Legarra A, Vitezica ZG, Bates RO, Ernst CW, Basso AL, Cantet RJ.

J Anim Breed Genet. 2016 Dec;133(6):452-462. doi: 10.1111/jbg.12217. Epub 2016 May 2.


The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.

Oecal S, Socher E, Uthoff M, Ernst C, Zaucke F, Sticht H, Baumann U, Gebauer JM.

J Biol Chem. 2016 Jun 10;291(24):12612-26. doi: 10.1074/jbc.M115.706069. Epub 2016 Apr 19.

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