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Items: 1 to 50 of 146

1.

Pharmacological properties of the central antihypertensive agent, moxonidine.

Edwards LP, Brown-Bryan TA, McLean L, Ernsberger P.

Cardiovasc Ther. 2012 Aug;30(4):199-208. doi: 10.1111/j.1755-5922.2011.00268.x. Epub 2011 Apr 5. Review.

PMID:
21884003
2.

Sitagliptin lowers glucagon and improves glucose tolerance in prediabetic obese SHROB rats.

Chen B, Moore A, Escobedo LV, Koletsky MS, Hou D, Koletsky RJ, Ernsberger P.

Exp Biol Med (Maywood). 2011 Mar;236(3):309-14. doi: 10.1258/ebm.2010.010161. Epub 2011 Feb 23.

PMID:
21345931
3.

Reproducible MRI measurement of adipose tissue volumes in genetic and dietary rodent obesity models.

Johnson DH, Flask CA, Ernsberger PR, Wong WC, Wilson DL.

J Magn Reson Imaging. 2008 Oct;28(4):915-27. doi: 10.1002/jmri.21481.

4.

High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets.

Sharma N, Okere IC, Barrows BR, Lei B, Duda MK, Yuan CL, Previs SF, Sharov VG, Azimzadeh AM, Ernsberger P, Hoit BD, Sabbah H, Stanley WC.

J Hypertens. 2008 Jul;26(7):1402-10. doi: 10.1097/HJH.0b013e3283007dda.

5.

Novel oxotremorine-related heterocyclic derivatives: Synthesis and in vitro pharmacology at the muscarinic receptor subtypes.

Dallanoce C, De Amici M, Barocelli E, Bertoni S, Roth BL, Ernsberger P, De Micheli C.

Bioorg Med Chem. 2007 Dec 15;15(24):7626-37. Epub 2007 Sep 11.

PMID:
17889543
6.

Allergic lung inflammation affects central noradrenergic control of cholinergic outflow to the airways in ferrets.

Wilson CG, Akhter S, Mayer CA, Kc P, Balan KV, Ernsberger P, Haxhiu MA.

J Appl Physiol (1985). 2007 Dec;103(6):2095-104. Epub 2007 Sep 13.

7.

Metabolic dysregulation in the SHROB rat reflects abnormal expression of transcription factors and enzymes that regulate carbohydrate metabolism.

Xu C, Arinze IJ, Johnson J, Tuy TT, Bone F, Ernsberger P, Massillon D.

J Nutr Biochem. 2008 May;19(5):305-12. Epub 2007 Aug 1.

PMID:
17683927
8.

Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome.

Ernsberger P, Johnson JL, Rosenthal T, Mirelman D, Koletsky RJ.

Am J Hypertens. 2007 Aug;20(8):866-74.

9.

High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet.

Sharma N, Okere IC, Duda MK, Johnson J, Yuan CL, Chandler MP, Ernsberger P, Hoit BD, Stanley WC.

Am J Hypertens. 2007 Apr;20(4):403-9.

PMID:
17386347
10.

Metabolic actions of angiotensin receptor antagonists: PPAR-gamma agonist actions or a class effect?

Ernsberger P, Koletsky RJ.

Curr Opin Pharmacol. 2007 Apr;7(2):140-5. Epub 2007 Feb 15. Review.

11.

Relating protein pharmacology by ligand chemistry.

Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK.

Nat Biotechnol. 2007 Feb;25(2):197-206.

PMID:
17287757
12.

Robust experiment design for estimating myocardial beta adrenergic receptor concentration using PET.

Salinas C, Muzic RF Jr, Ernsberger P, Saidel GM.

Med Phys. 2007 Jan;34(1):151-65.

PMID:
17278500
13.

Identification of IRAS/Nischarin as an I1-imidazoline receptor in PC12 rat pheochromocytoma cells.

Sun Z, Chang CH, Ernsberger P.

J Neurochem. 2007 Apr;101(1):99-108. Epub 2007 Jan 24.

14.

Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet.

Okere IC, Chandler MP, McElfresh TA, Rennison JH, Kung TA, Hoit BD, Ernsberger P, Young ME, Stanley WC.

Clin Exp Pharmacol Physiol. 2007 Jan-Feb;34(1-2):113-9.

PMID:
17201745
15.
16.

Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension.

Okere IC, Young ME, McElfresh TA, Chess DJ, Sharov VG, Sabbah HN, Hoit BD, Ernsberger P, Chandler MP, Stanley WC.

Hypertension. 2006 Dec;48(6):1116-23. Epub 2006 Oct 23.

PMID:
17060511
17.

Metabolic effects of antihypertensive agents: role of sympathoadrenal and renin-angiotensin systems.

Ernsberger P, Koletsky RJ.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Jul;373(4):245-58. Epub 2006 Jun 17. Review.

PMID:
16783586
18.

Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin.

Okere IC, Chandler MP, McElfresh TA, Rennison JH, Sharov V, Sabbah HN, Tserng KY, Hoit BD, Ernsberger P, Young ME, Stanley WC.

Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H38-44. Epub 2006 Jan 27.

19.

Lipid-lowering actions of imidazoline antihypertensive agents in metabolic syndrome X.

Velliquette RA, Kossover R, Previs SF, Ernsberger P.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Jan;372(4):300-12. Epub 2006 Jan 17.

PMID:
16416266
20.
21.

The epidemiology of overweight and obesity: public health crisis or moral panic?

Campos P, Saguy A, Ernsberger P, Oliver E, Gaesser G.

Int J Epidemiol. 2006 Feb;35(1):55-60. Epub 2005 Dec 8. No abstract available.

PMID:
16339599
22.

High-fat diet prevents cardiac hypertrophy and improves contractile function in the hypertensive dahl salt-sensitive rat.

Okere IC, Chess DJ, McElfresh TA, Johnson J, Rennison J, Ernsberger P, Hoit BD, Chandler MP, Stanley WC.

Clin Exp Pharmacol Physiol. 2005 Oct;32(10):825-31.

PMID:
16173943
23.

PET imaging of myocardial beta-adrenergic receptors with fluorocarazolol: lack of interference by endogenous catecholamines.

Salinas C, Muzic RF Jr, Berridge M, Ernsberger P.

J Cardiovasc Pharmacol. 2005 Aug;46(2):222-31.

PMID:
16044035
24.

The National Weight Control Registry: a critique.

Ikeda J, Amy NK, Ernsberger P, Gaesser GA, Berg FM, Clark CA, Parham ES, Peters P.

J Nutr Educ Behav. 2005 Jul-Aug;37(4):203-5.

PMID:
16029691
25.
26.

Strain-dependent beta-adrenergic receptor function influences myocardial responses to isoproterenol stimulation in mice.

Faulx MD, Ernsberger P, Vatner D, Hoffman RD, Lewis W, Strachan R, Hoit BD.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H30-6. Epub 2005 Mar 4.

27.

Imidazoleacetic acid-ribotide: an endogenous ligand that stimulates imidazol(in)e receptors.

Prell GD, Martinelli GP, Holstein GR, Matulić-Adamić J, Watanabe KA, Chan SL, Morgan NG, Haxhiu MA, Ernsberger P.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13677-82. Epub 2004 Sep 13.

28.

IRAS splice variants.

Piletz JE, Deleersnijder W, Roth BL, Ernsberger P, Zhu H, Ziegler D.

Ann N Y Acad Sci. 2003 Dec;1009:419-26.

PMID:
15028621
30.

Cardiac effects of moxonidine in spontaneously hypertensive obese rats.

Mukaddam-Daher S, Menaouar A, El-Ayoubi R, Gutkowska J, Jankowski M, Velliquette RA, Ernsberger P.

Ann N Y Acad Sci. 2003 Dec;1009:244-50.

PMID:
15028594
31.

Contrasting metabolic effects of antihypertensive agents.

Velliquette RA, Ernsberger P.

J Pharmacol Exp Ther. 2003 Dec;307(3):1104-11. Epub 2003 Oct 13.

PMID:
14557373
32.

Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands.

De Amici M, Conti P, Fasoli E, Barocelli E, Ballabeni V, Bertoni S, Impicciatore M, Roth BL, Ernsberger P, De Micheli C.

Farmaco. 2003 Sep;58(9):739-48. Erratum in: Farmaco. 2004 Apr;59(4):343.

PMID:
13679167
33.
34.

Mechanisms of altered vagal control in heart failure: influence of muscarinic receptors and acetylcholinesterase activity.

Dunlap ME, Bibevski S, Rosenberry TL, Ernsberger P.

Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1632-40. Epub 2003 Jun 26.

35.
36.

L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists.

Shi Q, Savage JE, Hufeisen SJ, Rauser L, Grajkowska E, Ernsberger P, Wroblewski JT, Nadeau JH, Roth BL.

J Pharmacol Exp Ther. 2003 Apr;305(1):131-42.

PMID:
12649361
37.

H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.

Kroeze WK, Hufeisen SJ, Popadak BA, Renock SM, Steinberg S, Ernsberger P, Jayathilake K, Meltzer HY, Roth BL.

Neuropsychopharmacology. 2003 Mar;28(3):519-26.

38.

Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

Roth BL, Baner K, Westkaemper R, Siebert D, Rice KC, Steinberg S, Ernsberger P, Rothman RB.

Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11934-9. Epub 2002 Aug 21.

39.

In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs.

Butterweck V, Nahrstedt A, Evans J, Hufeisen S, Rauser L, Savage J, Popadak B, Ernsberger P, Roth BL.

Psychopharmacology (Berl). 2002 Jul;162(2):193-202. Epub 2002 May 9.

PMID:
12110997
40.
41.
42.

The in vitro pharmacology of the beta-adrenergic receptor pet ligand (s)-fluorocarazolol reveals high affinity for cloned beta-adrenergic receptors and moderate affinity for the human 5-HT1A receptor.

Roth BL, Ernsberger P, Steinberg SA, Rao S, Rauser L, Savage J, Hufeisen S, Berridge MS, Muzic RF Jr.

Psychopharmacology (Berl). 2001 Aug;157(1):111-4.

PMID:
11512051
43.

Pharmacology of moxonidine: an I1-imidazoline receptor agonist.

Ernsberger P.

J Cardiovasc Pharmacol. 2000;35(7 Suppl 4):S27-41. Review.

PMID:
11346217
44.

Differential cardiorespiratory control elicited by activation of ventral medullary sites in mice.

Tolentino-Silva FP, Haxhiu MA, Ernsberger P, Waldbaum S, Dreshaj IA.

J Appl Physiol (1985). 2000 Aug;89(2):437-44.

45.

Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization.

Piletz JE, Ivanov TR, Sharp JD, Ernsberger P, Chang CH, Pickard RT, Gold G, Roth B, Zhu H, Jones JC, Baldwin J, Reis DJ.

DNA Cell Biol. 2000 Jun;19(6):319-29.

PMID:
10882231
46.

The SHROB model of syndrome X: effects of excess dietary sucrose.

Ernsberger P, Koletsky RJ, Kline DD, Bedol DM, Friedman JE.

Ann N Y Acad Sci. 1999 Nov 18;892:315-8. No abstract available.

PMID:
10842673
47.

Molecular pathology in the obese spontaneous hypertensive Koletsky rat: a model of syndrome X.

Ernsberger P, Koletsky RJ, Friedman JE.

Ann N Y Acad Sci. 1999 Nov 18;892:272-88.

PMID:
10842668
48.

alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice.

Tolentino-Silva FP, Haxhiu MA, Waldbaum S, Dreshaj IA, Ernsberger P.

Brain Res. 2000 Apr 17;862(1-2):26-35.

PMID:
10799665
49.

Alterations in respiratory behavior, brain neurochemistry and receptor density induced by pharmacologic suppression of sleep in the neonatal period.

Thomas AJ, Erokwu BO, Yamamoto BK, Ernsberger P, Bishara O, Strohl KP.

Brain Res Dev Brain Res. 2000 Apr 14;120(2):181-9.

PMID:
10775770
50.

Decreased transport of leptin across the blood-brain barrier in rats lacking the short form of the leptin receptor.

Kastin AJ, Pan W, Maness LM, Koletsky RJ, Ernsberger P.

Peptides. 1999 Dec;20(12):1449-53.

PMID:
10698121

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