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Fatigue scores correlate with other self-assessment data, but not with clinical and biomarker parameters, in CIS and RRMS.

Håkansson I, Johansson L, Dahle C, Vrethem M, Ernerudh J.

Mult Scler Relat Disord. 2019 Nov;36:101424. doi: 10.1016/j.msard.2019.101424. Epub 2019 Oct 1.


Low-molecular-weight-heparin increases Th1- and Th17-associated chemokine levels during pregnancy in women with unexplained recurrent pregnancy loss: a randomised controlled trial.

Rasmark Roepke E, Bruno V, Nedstrand E, Boij R, Strid CP, Piccione E, Berg G, Svensson-Arvelund J, Jenmalm MC, Rubér M, Ernerudh J.

Sci Rep. 2019 Aug 23;9(1):12314. doi: 10.1038/s41598-019-48799-6.


A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases.

Gawel DR, Serra-Musach J, Lilja S, Aagesen J, Arenas A, Asking B, Bengnér M, Björkander J, Biggs S, Ernerudh J, Hjortswang H, Karlsson JE, Köpsen M, Lee EJ, Lentini A, Li X, Magnusson M, Martínez-Enguita D, Matussek A, Nestor CE, Schäfer S, Seifert O, Sonmez C, Stjernman H, Tjärnberg A, Wu S, Åkesson K, Shalek AK, Stenmarker M, Zhang H, Gustafsson M, Benson M.

Genome Med. 2019 Jul 30;11(1):47. doi: 10.1186/s13073-019-0657-3.


Maternal, placental and cord blood cytokines and the risk of adverse birth outcomes among pregnant women infected with Schistosoma japonicum in the Philippines.

Abioye AI, McDonald EA, Park S, Joshi A, Kurtis JD, Wu H, Pond-Tor S, Sharma S, Ernerudh J, Baltazar P, Acosta LP, Olveda RM, Tallo V, Friedman JF.

PLoS Negl Trop Dis. 2019 Jun 12;13(6):e0007371. doi: 10.1371/journal.pntd.0007371. eCollection 2019 Jun.


Elevated levels of CRP and IL-8 are related to reduce survival time: 1-year follow-up measurements of different analytes in frail elderly nursing home residents.

Edvardsson M, Sund-Levander M, Milberg A, Ernerudh J, Grodzinsky E.

Scand J Clin Lab Invest. 2019 Sep;79(5):288-292. doi: 10.1080/00365513.2019.1609695. Epub 2019 May 10.


Different composition of leucocytes in cortical and cancellous bone healing in a mouse model.

Tätting L, Sandberg O, Bernhardsson M, Ernerudh J, Aspenberg P.

Bone Joint Res. 2019 Jan 4;7(12):620-628. doi: 10.1302/2046-3758.712.BJR-2017-0366.R2. eCollection 2018 Dec.


Marginal-Zone B-Cells Are Main Producers of IgM in Humans, and Are Reduced in Patients With Autoimmune Vasculitis.

Appelgren D, Eriksson P, Ernerudh J, Segelmark M.

Front Immunol. 2018 Oct 2;9:2242. doi: 10.3389/fimmu.2018.02242. eCollection 2018.


Maintained thymic output of conventional and regulatory T cells during human pregnancy.

Hellberg S, Mehta RB, Forsberg A, Berg G, Brynhildsen J, Winqvist O, Jenmalm MC, Ernerudh J.

J Allergy Clin Immunol. 2019 Feb;143(2):771-775.e7. doi: 10.1016/j.jaci.2018.09.023. Epub 2018 Oct 9. No abstract available.


Genome amplification and cellular senescence are hallmarks of human placenta development.

Velicky P, Meinhardt G, Plessl K, Vondra S, Weiss T, Haslinger P, Lendl T, Aumayr K, Mairhofer M, Zhu X, Schütz B, Hannibal RL, Lindau R, Weil B, Ernerudh J, Neesen J, Egger G, Mikula M, Röhrl C, Urban AE, Baker J, Knöfler M, Pollheimer J.

PLoS Genet. 2018 Oct 12;14(10):e1007698. doi: 10.1371/journal.pgen.1007698. eCollection 2018 Oct.


Immunological and Quality-of-Life Profiles in Women with Breast Cancer: Complementary versus Conventional Care.

Hamrin E, Ernerudh J, Rosén A.

Complement Med Res. 2018;25(6):391-397. doi: 10.1159/000490049. Epub 2018 Aug 27.


Oxylipins in cerebrospinal fluid in clinically isolated syndrome and relapsing remitting multiple sclerosis.

Håkansson I, Gouveia-Figueira S, Ernerudh J, Vrethem M, Ghafouri N, Ghafouri B, Nording M.

Prostaglandins Other Lipid Mediat. 2018 Sep;138:41-47. doi: 10.1016/j.prostaglandins.2018.08.003. Epub 2018 Aug 15.


Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis.

Håkansson I, Tisell A, Cassel P, Blennow K, Zetterberg H, Lundberg P, Dahle C, Vrethem M, Ernerudh J.

J Neuroinflammation. 2018 Jul 18;15(1):209. doi: 10.1186/s12974-018-1249-7.


Interleukin-34 is present at the fetal-maternal interface and induces immunoregulatory macrophages of a decidual phenotype in vitro.

Lindau R, Mehta RB, Lash GE, Papapavlou G, Boij R, Berg G, Jenmalm MC, Ernerudh J, Svensson-Arvelund J.

Hum Reprod. 2018 Apr 1;33(4):588-599. doi: 10.1093/humrep/dey037.


Anemia of Inflammation during Human Pregnancy Does Not Affect Newborn Iron Endowment.

Abioye AI, Park S, Ripp K, McDonald EA, Kurtis JD, Wu H, Pond-Tor S, Sharma S, Ernerudh J, Baltazar P, Acosta LP, Olveda RM, Tallo V, Friedman JF.

J Nutr. 2018 Mar 1;148(3):427-436. doi: 10.1093/jn/nxx052.


Effects of low molecular weight heparin on the polarization and cytokine profile of macrophages and T helper cells in vitro.

Bruno V, Svensson-Arvelund J, Rubér M, Berg G, Piccione E, Jenmalm MC, Ernerudh J.

Sci Rep. 2018 Mar 8;8(1):4166. doi: 10.1038/s41598-018-22418-2.


Immune profile in relation to sex steroid cyclicity in healthy women and women with multiple sclerosis.

Kempe P, Eklund D, Hallin A, Hammar M, Olsson T, Brynhildsen J, Ernerudh J.

J Reprod Immunol. 2018 Apr;126:53-59. doi: 10.1016/j.jri.2018.02.006. Epub 2018 Mar 2.


Cox-2 inhibition and the composition of inflammatory cell populations during early and mid-time tendon healing.

Blomgran P, Blomgran R, Ernerudh J, Aspenberg P.

Muscles Ligaments Tendons J. 2017 Sep 18;7(2):223-229. doi: 10.11138/mltj/2017.7.2.223. eCollection 2017 Apr-Jun.


Improved Precision of Automatic Brain Volume Measurements in Patients with Clinically Isolated Syndrome and Multiple Sclerosis Using Edema Correction.

Warntjes JBM, Tisell A, Håkansson I, Lundberg P, Ernerudh J.

AJNR Am J Neuroradiol. 2018 Feb;39(2):296-302. doi: 10.3174/ajnr.A5476. Epub 2017 Dec 14.


Pregnancy modulates the allergen-induced cytokine production differently in allergic and non-allergic women.

Abelius MS, Jedenfalk M, Ernerudh J, Janefjord C, Berg G, Matthiesen L, Jenmalm MC.

Pediatr Allergy Immunol. 2017 Dec;28(8):818-824. doi: 10.1111/pai.12802. Epub 2017 Oct 3.


Obituary: Leif Matthiesen, MD, PhD (1954-2017).

Sharma S, Berg G, Ernerudh J.

Am J Reprod Immunol. 2017 Oct;78(4). doi: 10.1111/aji.12740. Epub 2017 Aug 8. No abstract available.


CD4/CD8 ratio<1 is associated with lymphocyte subsets, CMV and gender in 71-year old individuals: 5-Year follow-up of the Swedish HEXA Immune Longitudinal Study.

Strindhall J, Löfgren S, Främsth C, Matussek A, Bengner M, Ernerudh J, Wikby A.

Exp Gerontol. 2017 Sep;95:82-87. doi: 10.1016/j.exger.2017.03.020. Epub 2017 May 2. No abstract available.


Annexin A1 in blood mononuclear cells from patients with coronary artery disease: Its association with inflammatory status and glucocorticoid sensitivity.

Bergström I, Lundberg AK, Jönsson S, Särndahl E, Ernerudh J, Jonasson L.

PLoS One. 2017 Mar 22;12(3):e0174177. doi: 10.1371/journal.pone.0174177. eCollection 2017.


Neurofilament light chain in cerebrospinal fluid and prediction of disease activity in clinically isolated syndrome and relapsing-remitting multiple sclerosis.

Håkansson I, Tisell A, Cassel P, Blennow K, Zetterberg H, Lundberg P, Dahle C, Vrethem M, Ernerudh J.

Eur J Neurol. 2017 May;24(5):703-712. doi: 10.1111/ene.13274. Epub 2017 Mar 6.


Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study.

Gyllemark P, Forsberg P, Ernerudh J, Henningsson AJ.

J Neuroinflammation. 2017 Feb 1;14(1):27. doi: 10.1186/s12974-017-0789-6.


Isolated metaphyseal injury influences unrelated bones.

Tätting L, Sandberg O, Bernhardsson M, Ernerudh J, Aspenberg P.

Acta Orthop. 2017 Apr;88(2):223-230. doi: 10.1080/17453674.2016.1274587. Epub 2017 Jan 27.


Cerebrospinal fluid levels of neurofilament and tau correlate with brain atrophy in natalizumab-treated multiple sclerosis.

Mellergård J, Tisell A, Blystad I, Grönqvist A, Blennow K, Olsson B, Dahle C, Vrethem M, Lundberg P, Ernerudh J.

Eur J Neurol. 2017 Jan;24(1):112-121. doi: 10.1111/ene.13162. Epub 2016 Oct 4.


Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis.

Hellberg S, Eklund D, Gawel DR, Köpsén M, Zhang H, Nestor CE, Kockum I, Olsson T, Skogh T, Kastbom A, Sjöwall C, Vrethem M, Håkansson I, Benson M, Jenmalm MC, Gustafsson M, Ernerudh J.

Cell Rep. 2016 Sep 13;16(11):2928-2939. doi: 10.1016/j.celrep.2016.08.036.


Factors associated with experience of fatigue, and functional limitations due to fatigue in patients with stable COPD.

Kentson M, Tödt K, Skargren E, Jakobsson P, Ernerudh J, Unosson M, Theander K.

Ther Adv Respir Dis. 2016 Oct;10(5):410-24. doi: 10.1177/1753465816661930. Epub 2016 Sep 1.


A possible link between loading, inflammation and healing: Immune cell populations during tendon healing in the rat.

Blomgran P, Blomgran R, Ernerudh J, Aspenberg P.

Sci Rep. 2016 Jul 13;6:29824. doi: 10.1038/srep29824.


Humoral response to influenza vaccination in relation to pre-vaccination antibody titres, vaccination history, cytomegalovirus serostatus and CD4/CD8 ratio.

Strindhall J, Ernerudh J, Mörner A, Waalen K, Löfgren S, Matussek A, Bengner M.

Infect Dis (Lond). 2016;48(6):436-42. doi: 10.3109/23744235.2015.1135252. Epub 2016 Jan 25.


Psychological Resources Are Independently Associated with Markers of Inflammation in a Middle-Aged Community Sample.

Marteinsdottir I, Ernerudh J, Jonasson L, Kristenson M, Garvin P.

Int J Behav Med. 2016 Oct;23(5):611-20. doi: 10.1007/s12529-016-9553-z.


A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases.

Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M.

Sci Transl Med. 2015 Nov 11;7(313):313ra178. doi: 10.1126/scitranslmed.aad2722.


Quantitative MRI for Analysis of Active Multiple Sclerosis Lesions without Gadolinium-Based Contrast Agent.

Blystad I, Håkansson I, Tisell A, Ernerudh J, Smedby Ö, Lundberg P, Larsson EM.

AJNR Am J Neuroradiol. 2016 Jan;37(1):94-100. doi: 10.3174/ajnr.A4501. Epub 2015 Oct 15.


Functional and homeostatic defects of regulatory T cells in patients with coronary artery disease.

Hasib L, Lundberg AK, Zachrisson H, Ernerudh J, Jonasson L.

J Intern Med. 2016 Jan;279(1):63-77. doi: 10.1111/joim.12398. Epub 2015 Aug 11.


The joint subclinical elevation of CRP and IL-6 is associated with lower health-related quality of life in comparison with no elevation or elevation of only one of the biomarkers.

Garvin P, Nilsson E, Ernerudh J, Kristenson M.

Qual Life Res. 2016 Jan;25(1):213-21. doi: 10.1007/s11136-015-1068-6. Epub 2015 Jul 21.


Regulatory T-cell Subpopulations in Severe or Early-onset Preeclampsia.

Boij R, Mjösberg J, Svensson-Arvelund J, Hjorth M, Berg G, Matthiesen L, Jenmalm MC, Ernerudh J.

Am J Reprod Immunol. 2015 Oct;74(4):368-78. doi: 10.1111/aji.12410. Epub 2015 Jun 27.


Decidual cytokines and pregnancy complications: focus on spontaneous miscarriage.

Lash GE, Ernerudh J.

J Reprod Immunol. 2015 Apr;108:83-9. doi: 10.1016/j.jri.2015.02.003. Epub 2015 Feb 28. Review.


The Role of Macrophages in Promoting and Maintaining Homeostasis at the Fetal-Maternal Interface.

Svensson-Arvelund J, Ernerudh J.

Am J Reprod Immunol. 2015 Aug;74(2):100-9. doi: 10.1111/aji.12357. Epub 2015 Jan 13. Review.


The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages.

Svensson-Arvelund J, Mehta RB, Lindau R, Mirrasekhian E, Rodriguez-Martinez H, Berg G, Lash GE, Jenmalm MC, Ernerudh J.

J Immunol. 2015 Feb 15;194(4):1534-44. doi: 10.4049/jimmunol.1401536. Epub 2015 Jan 5.


Clinical use of conventional reference intervals in the frail elderly.

Edvardsson M, Levander MS, Ernerudh J, Theodorsson E, Grodzinsky E.

J Eval Clin Pract. 2015 Apr;21(2):229-35. doi: 10.1111/jep.12294. Epub 2014 Dec 11.


The placental immune milieu is characterized by a Th2- and anti-inflammatory transcription profile, regardless of maternal allergy, and associates with neonatal immunity.

Abelius MS, Janefjord C, Ernerudh J, Berg G, Matthiesen L, Duchén K, Nilsson LJ, Jenmalm MC.

Am J Reprod Immunol. 2015 May;73(5):445-59. doi: 10.1111/aji.12350. Epub 2014 Dec 10.


Increase in Th17-associated CCL20 and decrease in Th2-associated CCL22 plasma chemokines in active ANCA-associated vasculitis.

Eriksson P, Andersson C, Cassel P, Nyström S, Ernerudh J.

Scand J Rheumatol. 2015;44(1):80-3. doi: 10.3109/03009742.2014.952332. Epub 2014 Oct 29. No abstract available.


Early cytokine release in response to live Borrelia burgdorferi Sensu Lato Spirochetes is largely complement independent.

Sandholm K, Henningsson AJ, Säve S, Bergström S, Forsberg P, Jonsson N, Ernerudh J, Ekdahl KN.

PLoS One. 2014 Sep 29;9(9):e108013. doi: 10.1371/journal.pone.0108013. eCollection 2014.


Sublingual immunotherapy alters expression of IL-4 and its soluble and membrane-bound receptors.

Nestor CE, Dadfar E, Ernerudh J, Gustafsson M, Björkander J, Benson M, Zhang H.

Allergy. 2014 Nov;69(11):1564-6. doi: 10.1111/all.12505. Epub 2014 Sep 13.


Th2-like chemokine levels are increased in allergic children and influenced by maternal immunity during pregnancy.

Abelius MS, Lempinen E, Lindblad K, Ernerudh J, Berg G, Matthiesen L, Nilsson LJ, Jenmalm MC.

Pediatr Allergy Immunol. 2014 Jun;25(4):387-93. doi: 10.1111/pai.12235.


GATA binding protein 3⁺ group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonates.

Forsberg A, Bengtsson M, Eringfält A, Ernerudh J, Mjösberg J, Jenmalm MC.

J Allergy Clin Immunol. 2014 Jul;134(1):228-30. doi: 10.1016/j.jaci.2014.01.027. Epub 2014 Mar 14. No abstract available.


Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment.

Gustafsson M, Edström M, Gawel D, Nestor CE, Wang H, Zhang H, Barrenäs F, Tojo J, Kockum I, Olsson T, Serra-Musach J, Bonifaci N, Pujana MA, Ernerudh J, Benson M.

Genome Med. 2014 Feb 26;6(2):17. doi: 10.1186/gm534. eCollection 2014.


Soluble Fas ligand is associated with natural killer cell dynamics in coronary artery disease.

Szymanowski A, Li W, Lundberg A, Evaldsson C, Nilsson L, Backteman K, Ernerudh J, Jonasson L.

Atherosclerosis. 2014 Apr;233(2):616-22. doi: 10.1016/j.atherosclerosis.2014.01.030. Epub 2014 Jan 24.


Increased B cell and cytotoxic NK cell proportions and increased T cell responsiveness in blood of natalizumab-treated multiple sclerosis patients.

Mellergård J, Edström M, Jenmalm MC, Dahle C, Vrethem M, Ernerudh J.

PLoS One. 2013 Dec 2;8(12):e81685. doi: 10.1371/journal.pone.0081685. eCollection 2013.


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