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Items: 39

1.

Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design.

Fjellström O, Akkaya S, Beisel HG, Eriksson PO, Erixon K, Gustafsson D, Jurva U, Kang D, Karis D, Knecht W, Nerme V, Nilsson I, Olsson T, Redzic A, Roth R, Sandmark J, Tigerström A, Öster L.

PLoS One. 2015 Jan 28;10(1):e0113705. doi: 10.1371/journal.pone.0113705. eCollection 2015.

2.

Quantification and repair of psoralen-induced interstrand crosslinks in human cells.

Vare D, Johansson F, Persson JO, Erixon K, Jenssen D.

Toxicol Lett. 2014 May 2;226(3):343-50. doi: 10.1016/j.toxlet.2014.01.019. Epub 2014 Feb 5.

PMID:
24508309
3.

Sub-ångström-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.

Lüdtke S, Neumann P, Erixon KM, Leeper F, Kluger R, Ficner R, Tittmann K.

Nat Chem. 2013 Sep;5(9):762-7. doi: 10.1038/nchem.1728. Epub 2013 Aug 18.

PMID:
23965678
4.

DNA double strand breaks induced by the indirect effect of radiation are more efficiently repaired by non-homologous end joining compared to homologous recombination repair.

Bajinskis A, Natarajan AT, Erixon K, Harms-Ringdahl M.

Mutat Res. 2013 Aug 30;756(1-2):21-9. doi: 10.1016/j.mrgentox.2013.06.012. Epub 2013 Jun 28.

PMID:
23811167
5.

DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells.

Vare D, Groth P, Carlsson R, Johansson F, Erixon K, Jenssen D.

DNA Repair (Amst). 2012 Dec 1;11(12):976-85. doi: 10.1016/j.dnarep.2012.09.010. Epub 2012 Oct 23.

PMID:
23099010
6.

CHK1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation.

Elvers I, Hagenkort A, Johansson F, Djureinovic T, Lagerqvist A, Schultz N, Stoimenov I, Erixon K, Helleday T.

Nucleic Acids Res. 2012 Sep 1;40(17):8440-8. Epub 2012 Jun 29.

7.

Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues.

Chen L, Cressina E, Dixon N, Erixon K, Agyei-Owusu K, Micklefield J, Smith AG, Abell C, Leeper FJ.

Org Biomol Chem. 2012 Aug 14;10(30):5924-31. doi: 10.1039/c2ob07116a. Epub 2012 Apr 19.

PMID:
22514012
8.

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.

Ström CE, Mortusewicz O, Finch D, Parsons JL, Lagerqvist A, Johansson F, Schultz N, Erixon K, Dianov GL, Helleday T.

DNA Repair (Amst). 2011 Sep 5;10(9):961-9. doi: 10.1016/j.dnarep.2011.07.004. Epub 2011 Aug 15.

PMID:
21840775
9.

DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells.

Lagerqvist A, Håkansson D, Lundin C, Prochazka G, Dreij K, Segerbäck D, Jernström B, Törnqvist M, Frank H, Seidel A, Erixon K, Jenssen D.

DNA Repair (Amst). 2011 Aug 15;10(8):877-86. doi: 10.1016/j.dnarep.2011.06.002. Epub 2011 Jul 2.

PMID:
21727035
10.

UV stalled replication forks restart by re-priming in human fibroblasts.

Elvers I, Johansson F, Groth P, Erixon K, Helleday T.

Nucleic Acids Res. 2011 Sep 1;39(16):7049-57. doi: 10.1093/nar/gkr420. Epub 2011 Jun 6.

11.

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.

Ström CE, Johansson F, Uhlén M, Szigyarto CA, Erixon K, Helleday T.

Nucleic Acids Res. 2011 Apr;39(8):3166-75. doi: 10.1093/nar/gkq1241. Epub 2010 Dec 22.

12.

Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis .

Pei XY, Erixon KM, Luisi BF, Leeper FJ.

Biochemistry. 2010 Mar 2;49(8):1727-36. doi: 10.1021/bi901864j.

13.

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.

Jansen JG, Tsaalbi-Shtylik A, Hendriks G, Gali H, Hendel A, Johansson F, Erixon K, Livneh Z, Mullenders LH, Haracska L, de Wind N.

Mol Cell Biol. 2009 Jun;29(11):3113-23. doi: 10.1128/MCB.00071-09. Epub 2009 Mar 30.

14.

Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold.

Erixon KM, Dabalos CL, Leeper FJ.

Org Biomol Chem. 2008 Oct 7;6(19):3561-72. doi: 10.1039/b806580b. Epub 2008 Jul 11.

PMID:
19082157
15.

Cyclobutane pyrimidine dimers do not fully explain the mutagenicity induced by UVA in Chinese hamster cells.

Biverstål A, Johansson F, Jenssen D, Erixon K.

Mutat Res. 2008 Dec 15;648(1-2):32-9. doi: 10.1016/j.mrfmmm.2008.09.011. Epub 2008 Oct 4.

PMID:
18950648
16.

Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide.

Lagerqvist A, Håkansson D, Prochazka G, Lundin C, Dreij K, Segerbäck D, Jernström B, Törnqvist M, Seidel A, Erixon K, Jenssen D.

DNA Repair (Amst). 2008 Aug 2;7(8):1202-12. doi: 10.1016/j.dnarep.2008.03.022. Epub 2008 May 13.

PMID:
18479980
17.

Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics.

Erixon KM, Dabalos CL, Leeper FJ.

Chem Commun (Camb). 2007 Mar 7;(9):960-2. Epub 2006 Dec 8.

PMID:
17311134
18.

Caffeine delays replication fork progression and enhances UV-induced homologous recombination in Chinese hamster cell lines.

Johansson F, Lagerqvist A, Filippi S, Palitti F, Erixon K, Helleday T, Jenssen D.

DNA Repair (Amst). 2006 Dec 9;5(12):1449-58. Epub 2006 Sep 11.

PMID:
16968677
19.

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.

Lundin C, North M, Erixon K, Walters K, Jenssen D, Goldman AS, Helleday T.

Nucleic Acids Res. 2005 Jul 11;33(12):3799-811. Print 2005. Erratum in: Nucleic Acids Res. 2012 Jul;40(12):5794.

20.

Mutagenicity and DNA repair of glycidamide-induced adducts in mammalian cells.

Johansson F, Lundell T, Rydberg P, Erixon K, Jenssen D.

Mutat Res. 2005 Feb 7;580(1-2):81-9.

PMID:
15668110
22.

Screening for genotoxicity using the DRAG assay: investigation of halogenated environmental contaminants.

Johansson F, Allkvist A, Erixon K, Malmvärn A, Nilsson R, Bergman A, Helleday T, Jenssen D.

Mutat Res. 2004 Sep 12;563(1):35-47.

PMID:
15324747
23.

Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells.

Lundin C, Erixon K, Arnaudeau C, Schultz N, Jenssen D, Meuth M, Helleday T.

Mol Cell Biol. 2002 Aug;22(16):5869-78.

25.
26.

Clonogenic cell survival and rejoining of DNA double-strand breaks: comparisons between three cell lines after photon or He ion irradiation.

Stenerlöw B, Carlsson J, Blomquist E, Erixon K.

Int J Radiat Biol. 1994 Jun;65(6):631-9. Erratum in: Int J Radiat Biol 1996 Sep;70(3):373.

PMID:
7912712
27.

On the mechanism of the hepatocarcinogenicity of peroxisome proliferators.

Nilsson R, Beije B, Préat V, Erixon K, Ramel C.

Chem Biol Interact. 1991;78(2):235-50.

PMID:
2040027
28.

Differential regulation of base and nucleotide excision repair in mammalian cells.

Erixon K.

Basic Life Sci. 1986;38:159-70. No abstract available.

PMID:
3741329
30.

A transient post-irradiation defect in newly synthesised DNA.

Cramp WA, George AM, Lunec J, Harris G, Olsen I, Lewis PD, Chamberlain S, Ahnstrom G, Erixon K.

Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Nov;40(5):573-9. No abstract available.

PMID:
6975263
32.
33.

Proceedings: Effects of hydroxyurea and 5-fluorodeoxyuridine on excision repair in human cells.

Erixon K, Johansson B, Ahnström G.

Br J Cancer. 1975 Dec;32(6):759. No abstract available.

34.
35.

Radiation induced strand breakage in DNA from mammalian cells. Strand separation in alkaline solution.

Ahnström G, Erixon K.

Int J Radiat Biol Relat Stud Phys Chem Med. 1973 Mar;23(3):285-9. No abstract available.

PMID:
4633439
36.

The redox state of cytochrome b 559 in spinach chloroplasts.

Erixon K, Lozier R, Butler WL.

Biochim Biophys Acta. 1972 May 25;267(2):375-82. No abstract available.

PMID:
5042841
37.

Destruction of C-550 by ultraviolet radiation.

Erixon K, Butler WL.

Biochim Biophys Acta. 1971 Dec 7;253(2):483-6. No abstract available.

PMID:
5133538
38.

The effects of lipase on spinach and Chlamydomonas chloroplasts.

Okayama S, Epel BL, Erixon K, Lozier R, Butler WL.

Biochim Biophys Acta. 1971 Dec 7;253(2):476-82. No abstract available.

PMID:
4332307
39.

The relationship between Q, C- 550 and cytochrome b 559 in photoreactions at -196 degrees in chloroplasts.

Erixon K, Butler WL.

Biochim Biophys Acta. 1971 Jun 15;234(3):381-9. No abstract available.

PMID:
5117578

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