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Items: 17

1.

Lower mitochondrial DNA content but not increased mutagenesis associates with decreased base excision repair activity in brains of AD subjects.

Soltys DT, Pereira CPM, Rowies FT, Farfel JM, Grinberg LT, Suemoto CK, Leite REP, Rodriguez RD, Ericson NG, Bielas JH, Souza-Pinto NC.

Neurobiol Aging. 2019 Jan;73:161-170. doi: 10.1016/j.neurobiolaging.2018.09.015. Epub 2018 Sep 22.

PMID:
30359878
2.

Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans.

Haroon S, Li A, Weinert JL, Fritsch C, Ericson NG, Alexander-Floyd J, Braeckman BP, Haynes CM, Bielas JH, Gidalevitz T, Vermulst M.

Cell Rep. 2018 Mar 20;22(12):3115-3125. doi: 10.1016/j.celrep.2018.02.099.

3.

Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects.

Crouch ML, Knowels G, Stuppard R, Ericson NG, Bielas JH, Marcinek DJ, Syrjala KL.

PLoS One. 2017 Jul 10;12(7):e0181086. doi: 10.1371/journal.pone.0181086. eCollection 2017.

4.

Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression.

Nivison MP, Ericson NG, Green VM, Bielas JH, Campbell JS, Horner PJ.

Exp Neurol. 2017 Oct;296:49-61. doi: 10.1016/j.expneurol.2017.07.001. Epub 2017 Jul 3.

5.

Massively parallel digital transcriptional profiling of single cells.

Zheng GX, Terry JM, Belgrader P, Ryvkin P, Bent ZW, Wilson R, Ziraldo SB, Wheeler TD, McDermott GP, Zhu J, Gregory MT, Shuga J, Montesclaros L, Underwood JG, Masquelier DA, Nishimura SY, Schnall-Levin M, Wyatt PW, Hindson CM, Bharadwaj R, Wong A, Ness KD, Beppu LW, Deeg HJ, McFarland C, Loeb KR, Valente WJ, Ericson NG, Stevens EA, Radich JP, Mikkelsen TS, Hindson BJ, Bielas JH.

Nat Commun. 2017 Jan 16;8:14049. doi: 10.1038/ncomms14049.

6.

Mitochondrial DNA exhibits resistance to induced point and deletion mutations.

Valente WJ, Ericson NG, Long AS, White PA, Marchetti F, Bielas JH.

Nucleic Acids Res. 2016 Oct 14;44(18):8513-8524. Epub 2016 Aug 22.

7.

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.

Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, Rowley D, Ittmann M, Nelson PS.

Mol Cancer Res. 2016 Apr;14(4):374-84. doi: 10.1158/1541-7786.MCR-15-0330. Epub 2016 Jan 11.

8.

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.

Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H.

Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16.

9.

Targeted single molecule mutation detection with massively parallel sequencing.

Gregory MT, Bertout JA, Ericson NG, Taylor SD, Mukherjee R, Robins HS, Drescher CW, Bielas JH.

Nucleic Acids Res. 2016 Feb 18;44(3):e22. doi: 10.1093/nar/gkv915. Epub 2015 Sep 17.

10.

Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects.

Karunadharma PP, Basisty N, Dai DF, Chiao YA, Quarles EK, Hsieh EJ, Crispin D, Bielas JH, Ericson NG, Beyer RP, MacKay VL, MacCoss MJ, Rabinovitch PS.

Aging Cell. 2015 Aug;14(4):547-57. doi: 10.1111/acel.12317. Epub 2015 Mar 23.

11.

Skeletal muscle mitochondrial DNA deletions are not increased in CuZn-superoxide dismutase deficient mice.

Wanagat J, Ahmadieh N, Bielas JH, Ericson NG, Van Remmen H.

Exp Gerontol. 2015 Jan;61:15-9. doi: 10.1016/j.exger.2014.11.012. Epub 2014 Nov 20.

12.

Digital genomic quantification of tumor-infiltrating lymphocytes.

Robins HS, Ericson NG, Guenthoer J, O'Briant KC, Tewari M, Drescher CW, Bielas JH.

Sci Transl Med. 2013 Dec 4;5(214):214ra169. doi: 10.1126/scitranslmed.3007247.

13.

Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain.

Taylor SD, Ericson NG, Burton JN, Prolla TA, Silber JR, Shendure J, Bielas JH.

Aging Cell. 2014 Feb;13(1):29-38. doi: 10.1111/acel.12146. Epub 2013 Sep 11.

14.

Decreased mitochondrial DNA mutagenesis in human colorectal cancer.

Ericson NG, Kulawiec M, Vermulst M, Sheahan K, O'Sullivan J, Salk JJ, Bielas JH.

PLoS Genet. 2012;8(6):e1002689. doi: 10.1371/journal.pgen.1002689. Epub 2012 Jun 7.

15.

Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication.

Allen JM, Simcha DM, Ericson NG, Alexander DL, Marquette JT, Van Biber BP, Troll CJ, Karchin R, Bielas JH, Loeb LA, Camps M.

Nucleic Acids Res. 2011 Sep 1;39(16):7020-33. doi: 10.1093/nar/gkr157. Epub 2011 May 26.

16.

Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer.

Kulawiec M, Salk JJ, Ericson NG, Wanagat J, Bielas JH.

Environ Mol Mutagen. 2010 Jun;51(5):427-39. doi: 10.1002/em.20582. Review.

PMID:
20544883
17.

Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells.

Bielas JH, Schmitt MW, Icreverzi A, Ericson NG, Loeb LA.

Hum Gene Ther. 2009 Dec;20(12):1703-7. doi: 10.1089/hum.2009.053.

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