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Items: 1 to 50 of 152

1.

Neurogranin as a potential synaptic marker in the cerebrospinal fluid of patients with a first episode psychosis.

Santillo AF, Lundgren S, Xu C, Orhan F, Fatouros-Bergman H, Blennow K, Zetterberg H, Portelius E; Karolinska Schizophrenia Project (KaSP) Consortium, Cervenka S, Jönsson EG, Erhardt S, Engberg G.

Schizophr Res. 2019 Jun;208:490-492. doi: 10.1016/j.schres.2019.01.010. Epub 2019 Feb 4. No abstract available.

PMID:
30733168
2.

Peripheral and central levels of kynurenic acid in bipolar disorder subjects and healthy controls.

Sellgren CM, Gracias J, Jungholm O, Perlis RH, Engberg G, Schwieler L, Landen M, Erhardt S.

Transl Psychiatry. 2019 Jan 29;9(1):37. doi: 10.1038/s41398-019-0378-9.

3.

Increased peripheral levels of TARC/CCL17 in first episode psychosis patients.

Malmqvist A, Schwieler L, Orhan F, Fatouros-Bergman H, Bauer M, Flyckt L, Cervenka S, Engberg G, Piehl F; Karolinska Schizophrenia Project (KaSP) consortium, Erhardt S.

Schizophr Res. 2019 Jan 3. pii: S0920-9964(18)30729-1. doi: 10.1016/j.schres.2018.12.033. [Epub ahead of print]

PMID:
30612841
4.

TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress.

Lafarga V, Sung HM, Haneke K, Roessig L, Pauleau AL, Bruer M, Rodriguez-Acebes S, Lopez-Contreras AJ, Gruss OJ, Erhardt S, Mendez J, Fernandez-Capetillo O, Stoecklin G.

EMBO Rep. 2019 Jan;20(1). pii: e46224. doi: 10.15252/embr.201846224. Epub 2018 Dec 11.

5.

Increased number of monocytes and plasma levels of MCP-1 and YKL-40 in first-episode psychosis.

Orhan F, Schwieler L, Fatouros-Bergman H, Malmqvist A, Cervenka S, Collste K, Flyckt L, Farde L, Sellgren CM, Piehl F; Karolinska Schizophrenia Project (KaSP) Consortium, Engberg G, Erhardt S.

Acta Psychiatr Scand. 2018 Nov;138(5):432-440. doi: 10.1111/acps.12944. Epub 2018 Aug 21.

PMID:
30132802
6.

Importance of kynurenine 3-monooxygenase for spontaneous firing and pharmacological responses of midbrain dopamine neurons: Relevance for schizophrenia.

Tufvesson-Alm M, Schwieler L, Schwarcz R, Goiny M, Erhardt S, Engberg G.

Neuropharmacology. 2018 Aug;138:130-139. doi: 10.1016/j.neuropharm.2018.06.003. Epub 2018 Jun 5.

PMID:
29879409
7.

Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression.

Price JB, Bronars C, Erhardt S, Cullen KR, Schwieler L, Berk M, Walder K, McGee SL, Frye MA, Tye SJ.

Neurosci Biobehav Rev. 2018 Jul;90:212-220. doi: 10.1016/j.neubiorev.2018.04.002. Epub 2018 Apr 12. Review.

PMID:
29656032
8.

Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients.

Checa A, Malmqvist A, Flyckt L, Schwieler L, Samuelsson M, Skogh E, Cervenka S, Dahl ML, Piehl F; Karolinska Schizophrenia Project (KaSP) Consortium, Erhardt S, Wheelock CE.

Schizophr Res. 2018 Sep;199:438-441. doi: 10.1016/j.schres.2018.03.029. Epub 2018 Apr 4. No abstract available.

PMID:
29627172
9.

In Vivo Analysis of Centromeric Proteins Reveals a Stem Cell-Specific Asymmetry and an Essential Role in Differentiated, Non-proliferating Cells.

García Del Arco A, Edgar BA, Erhardt S.

Cell Rep. 2018 Feb 20;22(8):1982-1993. doi: 10.1016/j.celrep.2018.01.079.

10.

LPS-induced cortical kynurenic acid and neurogranin-NFAT signaling is associated with deficits in stimulus processing during Pavlovian conditioning.

Oliveros A, Wininger K, Sens J, Larsson MK, Liu XC, Choi S, Faka A, Schwieler L, Engberg G, Erhardt S, Choi DS.

J Neuroimmunol. 2017 Dec 15;313:1-9. doi: 10.1016/j.jneuroim.2017.09.010. Epub 2017 Sep 28.

11.

Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO).

Nagel G, Weber D, Fromm E, Erhardt S, Lübbert M, Fiedler W, Kindler T, Krauter J, Brossart P, Kündgen A, Salih HR, Westermann J, Wulf G, Hertenstein B, Wattad M, Götze K, Kraemer D, Heinicke T, Girschikofsky M, Derigs HG, Horst HA, Rudolph C, Heuser M, Göhring G, Teleanu V, Bullinger L, Thol F, Gaidzik VI, Paschka P, Döhner K, Ganser A, Döhner H, Schlenk RF; German-Austrian AML Study Group (AMLSG).

Ann Hematol. 2017 Dec;96(12):1993-2003. doi: 10.1007/s00277-017-3150-3. Epub 2017 Oct 31.

12.

First-episode psychosis patients display increased plasma IL-18 that correlates with cognitive dysfunction.

Orhan F, Fatouros-Bergman H, Schwieler L, Cervenka S, Flyckt L, Sellgren CM; Karolinska Schizophrenia Project (KaSP) consortium, Engberg G, Erhardt S.

Schizophr Res. 2018 May;195:406-408. doi: 10.1016/j.schres.2017.09.016. Epub 2017 Sep 23. No abstract available.

PMID:
28951075
13.

Metformin selectively targets redox control of complex I energy transduction.

Cameron AR, Logie L, Patel K, Erhardt S, Bacon S, Middleton P, Harthill J, Forteath C, Coats JT, Kerr C, Curry H, Stewart D, Sakamoto K, Repiščák P, Paterson MJ, Hassinen I, McDougall G, Rena G.

Redox Biol. 2018 Apr;14:187-197. doi: 10.1016/j.redox.2017.08.018. Epub 2017 Aug 26.

14.

Chromatin-associated noncoding RNAs in development and inheritance.

Acharya S, Hartmann M, Erhardt S.

Wiley Interdiscip Rev RNA. 2017 Nov;8(6). doi: 10.1002/wrna.1435. Epub 2017 Aug 25. Review.

PMID:
28840663
15.

Post-translational Modifications of Centromeric Chromatin.

García Del Arco A, Erhardt S.

Prog Mol Subcell Biol. 2017;56:213-231. doi: 10.1007/978-3-319-58592-5_9. Review.

PMID:
28840239
16.

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells.

Nötzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S.

Sci Rep. 2017 May 23;7(1):2265. doi: 10.1038/s41598-017-02357-0.

17.

Twelve-week physical exercise does not have a long-lasting effect on kynurenines in plasma of depressed patients.

Millischer V, Erhardt S, Ekblom Ö, Forsell Y, Lavebratt C.

Neuropsychiatr Dis Treat. 2017 Mar 31;13:967-972. doi: 10.2147/NDT.S131746. eCollection 2017.

18.

CSF GABA is reduced in first-episode psychosis and associates to symptom severity.

Orhan F, Fatouros-Bergman H, Goiny M, Malmqvist A, Piehl F; Karolinska Schizophrenia Project (KaSP) Consortium, Cervenka S, Collste K, Victorsson P, Sellgren CM, Flyckt L, Erhardt S, Engberg G.

Mol Psychiatry. 2018 May;23(5):1244-1250. doi: 10.1038/mp.2017.25. Epub 2017 Mar 14.

19.

Epidemiology of amyotrophic lateral sclerosis in Southern Germany.

Rosenbohm A, Peter RS, Erhardt S, Lulé D, Rothenbacher D, Ludolph AC, Nagel G; ALS Registry Study Group.

J Neurol. 2017 Apr;264(4):749-757. doi: 10.1007/s00415-017-8413-3. Epub 2017 Feb 20.

PMID:
28220290
20.

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28.

Collste K, Plavén-Sigray P, Fatouros-Bergman H, Victorsson P, Schain M, Forsberg A, Amini N, Aeinehband S; Karolinska Schizophrenia Project (KaSP) consortium, Erhardt S, Halldin C, Flyckt L, Farde L, Cervenka S.

Mol Psychiatry. 2017 Jun;22(6):850-856. doi: 10.1038/mp.2016.247. Epub 2017 Feb 14.

PMID:
28194003
21.

Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders.

Erhardt S, Pocivavsek A, Repici M, Liu XC, Imbeault S, Maddison DC, Thomas MAR, Smalley JL, Larsson MK, Muchowski PJ, Giorgini F, Schwarcz R.

Biol Psychiatry. 2017 Nov 15;82(10):756-765. doi: 10.1016/j.biopsych.2016.12.011. Epub 2016 Dec 16.

22.

Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.

Kegel ME, Johansson V, Wetterberg L, Bhat M, Schwieler L, Cannon TD, Schuppe-Koistinen I, Engberg G, Landén M, Hultman CM, Erhardt S.

Psychiatry Res. 2017 Jan;247:105-112. doi: 10.1016/j.psychres.2016.11.017. Epub 2016 Nov 16.

PMID:
27886578
23.

Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-like Receptor Stimulation in Peripheral Monocytes.

Orhan F, Bhat M, Sandberg K, Ståhl S, Piehl F; Karolinska Schizophrenia Project (KaSP) consortium, Svensson C, Erhardt S, Schwieler L.

Scand J Immunol. 2016 Nov;84(5):262-271. doi: 10.1111/sji.12479.

24.

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.

Brundin L, Sellgren CM, Lim CK, Grit J, Pålsson E, Landén M, Samuelsson M, Lundgren K, Brundin P, Fuchs D, Postolache TT, Traskman-Bendz L, Guillemin GJ, Erhardt S.

Transl Psychiatry. 2016 Aug 2;6(8):e865. doi: 10.1038/tp.2016.133.

25.

Decreased levels of kynurenic acid in prefrontal cortex in a genetic animal model of depression.

Liu XC, Erhardt S, Goiny M, Engberg G, Mathé AA.

Acta Neuropsychiatr. 2017 Feb;29(1):54-58. doi: 10.1017/neu.2016.31. Epub 2016 Jul 13.

PMID:
27406788
26.

Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects.

Coccaro EF, Lee R, Fanning JR, Fuchs D, Goiny M, Erhardt S, Christensen K, Brundin L, Coussons-Read M.

Psychoneuroendocrinology. 2016 Sep;71:189-96. doi: 10.1016/j.psyneuen.2016.04.024. Epub 2016 May 6.

27.

EWS-FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway.

Mutz CN, Schwentner R, Kauer MO, Katschnig AM, Kromp F, Aryee DN, Erhardt S, Goiny M, Alonso J, Fuchs D, Kovar H.

FEBS Lett. 2016 Jul;590(14):2063-75. doi: 10.1002/1873-3468.12243. Epub 2016 Jun 21.

28.

The kynurenine pathway in schizophrenia and bipolar disorder.

Erhardt S, Schwieler L, Imbeault S, Engberg G.

Neuropharmacology. 2017 Jan;112(Pt B):297-306. doi: 10.1016/j.neuropharm.2016.05.020. Epub 2016 May 28. Review.

PMID:
27245499
29.

Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.

Larsson MK, Faka A, Bhat M, Imbeault S, Goiny M, Orhan F, Oliveros A, Ståhl S, Liu XC, Choi DS, Sandberg K, Engberg G, Schwieler L, Erhardt S.

Neurochem Res. 2016 Sep;41(9):2243-55. doi: 10.1007/s11064-016-1939-4. Epub 2016 May 10.

PMID:
27165635
30.

Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans.

Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC.

Am J Physiol Cell Physiol. 2016 May 15;310(10):C836-40. doi: 10.1152/ajpcell.00053.2016. Epub 2016 Mar 30.

31.

Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes.

Mudry JM, Alm PS, Erhardt S, Goiny M, Fritz T, Caidahl K, Zierath JR, Krook A, Wallberg-Henriksson H.

Diabetes Metab Res Rev. 2016 Oct;32(7):754-761. doi: 10.1002/dmrr.2798. Epub 2016 May 1.

PMID:
26946084
32.

Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients.

Schwieler L, Samuelsson M, Frye MA, Bhat M, Schuppe-Koistinen I, Jungholm O, Johansson AG, Landén M, Sellgren CM, Erhardt S.

J Neuroinflammation. 2016 Feb 29;13(1):51. doi: 10.1186/s12974-016-0517-7.

33.

The CD44 ligand hyaluronic acid is elevated in the cerebrospinal fluid of suicide attempters and is associated with increased blood-brain barrier permeability.

Ventorp F, Barzilay R, Erhardt S, Samuelsson M, Träskman-Bendz L, Janelidze S, Weizman A, Offen D, Brundin L.

J Affect Disord. 2016 Mar 15;193:349-54. doi: 10.1016/j.jad.2015.12.069. Epub 2016 Jan 6.

PMID:
26796235
34.

No longer a nuisance: long non-coding RNAs join CENP-A in epigenetic centromere regulation.

Rošić S, Erhardt S.

Cell Mol Life Sci. 2016 Apr;73(7):1387-98. doi: 10.1007/s00018-015-2124-7. Epub 2016 Jan 9. Review.

PMID:
26748759
35.

A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder.

Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, Vawter MP, Backlund L, Sullivan PF, Sklar P, Smoller JW, Magnusson PK, Hultman CM, Walther-Jallow L, Svensson CI, Lichtenstein P, Schalling M, Engberg G, Erhardt S, Landén M.

Mol Psychiatry. 2016 Oct;21(10):1342-50. doi: 10.1038/mp.2015.186. Epub 2015 Dec 15.

36.

Inhibition of kynurenine aminotransferase II reduces activity of midbrain dopamine neurons.

Linderholm KR, Alm MT, Larsson MK, Olsson SK, Goiny M, Hajos M, Erhardt S, Engberg G.

Neuropharmacology. 2016 Mar;102:42-7. doi: 10.1016/j.neuropharm.2015.10.028. Epub 2015 Oct 24.

37.

[New findings about schizophrenia can provide new diagnostics and treatment].

Schalling M, Engberg G, Andreassen O, Erhardt S, Cunningham J, Agartz I, Petrovic P, Cervenka S, Fatouros-Bergman H.

Lakartidningen. 2015 Oct 13;112. pii: DH34. Review. Swedish.

38.

Chronic Antipsychotic Treatment in the Rat - Effects on Brain Interleukin-8 and Kynurenic Acid.

Larsson MK, Schwieler L, Goiny M, Erhardt S, Engberg G.

Int J Tryptophan Res. 2015 Sep 20;8:49-52. doi: 10.4137/IJTR.S25915. eCollection 2015.

39.

The role of inflammation in suicidal behaviour.

Brundin L, Erhardt S, Bryleva EY, Achtyes ED, Postolache TT.

Acta Psychiatr Scand. 2015 Sep;132(3):192-203. doi: 10.1111/acps.12458. Review.

40.

Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms.

Aeinehband S, Brenner P, Ståhl S, Bhat M, Fidock MD, Khademi M, Olsson T, Engberg G, Jokinen J, Erhardt S, Piehl F.

Brain Behav Immun. 2016 Jan;51:47-55. doi: 10.1016/j.bbi.2015.07.016. Epub 2015 Jul 17.

PMID:
26189678
41.

A microsurgical bifurcation rabbit model to investigate the effect of high-intensity focused ultrasound on aneurysms: a technical note.

Coluccia D, Fandino J, Marbacher S, Erhardt S, Kienzler J, Martin E, Werner B.

J Ther Ultrasound. 2014 Oct 31;2:21. doi: 10.1186/2050-5736-2-21. eCollection 2014.

42.

Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.

Schwieler L, Larsson MK, Skogh E, Kegel ME, Orhan F, Abdelmoaty S, Finn A, Bhat M, Samuelsson M, Lundberg K, Dahl ML, Sellgren C, Schuppe-Koistinen I, Svensson C, Erhardt S, Engberg G.

J Psychiatry Neurosci. 2015 Mar;40(2):126-33.

43.

Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division.

Rošić S, Köhler F, Erhardt S.

J Cell Biol. 2014 Nov 10;207(3):335-49. doi: 10.1083/jcb.201404097. Epub 2014 Nov 3. Erratum in: J Cell Biol. 2014 Dec 8;207(5):673.

44.

The rabbit shunt model of subarachnoid haemorrhage.

Marbacher S, Nevzati E, Croci D, Erhardt S, Muroi C, Jakob SM, Fandino J.

Transl Stroke Res. 2014 Dec;5(6):669-80. doi: 10.1007/s12975-014-0369-3. Epub 2014 Oct 19.

PMID:
25326333
45.

Imbalanced kynurenine pathway in schizophrenia.

Kegel ME, Bhat M, Skogh E, Samuelsson M, Lundberg K, Dahl ML, Sellgren C, Schwieler L, Engberg G, Schuppe-Koistinen I, Erhardt S.

Int J Tryptophan Res. 2014 Sep 16;7:15-22. doi: 10.4137/IJTR.S16800. eCollection 2014.

46.

Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression.

Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL.

Cell. 2014 Sep 25;159(1):33-45. doi: 10.1016/j.cell.2014.07.051.

47.

Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels.

Janelidze S, Suchankova P, Ekman A, Erhardt S, Sellgren C, Samuelsson M, Westrin A, Minthon L, Hansson O, Träskman-Bendz L, Brundin L.

Acta Psychiatr Scand. 2015 Apr;131(4):269-78. doi: 10.1111/acps.12339. Epub 2014 Sep 24.

PMID:
25251027
48.

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality.

Bay-Richter C, Linderholm KR, Lim CK, Samuelsson M, Träskman-Bendz L, Guillemin GJ, Erhardt S, Brundin L.

Brain Behav Immun. 2015 Jan;43:110-7. doi: 10.1016/j.bbi.2014.07.012. Epub 2014 Aug 12.

PMID:
25124710
49.

Kynurenic Acid levels in cerebrospinal fluid from patients with Alzheimer's disease or dementia with lewy bodies.

Wennström M, Nielsen HM, Orhan F, Londos E, Minthon L, Erhardt S.

Int J Tryptophan Res. 2014 Apr 28;7:1-7. doi: 10.4137/IJTR.S13958. eCollection 2014.

50.

The histone-fold protein CHRAC14 influences chromatin composition in response to DNA damage.

Mathew V, Pauleau AL, Steffen N, Bergner A, Becker PB, Erhardt S.

Cell Rep. 2014 Apr 24;7(2):321-330. doi: 10.1016/j.celrep.2014.03.008. Epub 2014 Apr 3.

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