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Items: 1 to 50 of 51

1.

Fascin-1 Is a Novel Prognostic Biomarker Associated With Tumor Invasiveness in Adrenocortical Carcinoma.

Poli G, Ruggiero C, Cantini G, Canu L, Baroni G, Armignacco R, Jouinot A, Santi R, Ercolino T, Ragazzon B, Assie G, Mannelli M, Nesi G, Lalli E, Luconi M.

J Clin Endocrinol Metab. 2019 May 1;104(5):1712-1724. doi: 10.1210/jc.2018-01717.

PMID:
30476173
2.

Metabolome-guided genomics to identify pathogenic variants in isocitrate dehydrogenase, fumarate hydratase, and succinate dehydrogenase genes in pheochromocytoma and paraganglioma.

Richter S, Gieldon L, Pang Y, Peitzsch M, Huynh T, Leton R, Viana B, Ercolino T, Mangelis A, Rapizzi E, Menschikowski M, Aust D, Kroiss M, Beuschlein F, Gudziol V, Timmers HJ, Lenders J, Mannelli M, Cascon A, Pacak K, Robledo M, Eisenhofer G, Klink B.

Genet Med. 2019 Mar;21(3):705-717. doi: 10.1038/s41436-018-0106-5. Epub 2018 Jul 27.

3.

Adrenocortical carcinoma: the dawn of a new era of genomic and molecular biology analysis.

Armignacco R, Cantini G, Canu L, Poli G, Ercolino T, Mannelli M, Luconi M.

J Endocrinol Invest. 2018 May;41(5):499-507. doi: 10.1007/s40618-017-0775-y. Epub 2017 Oct 28. Review.

PMID:
29080966
4.

New insights in the clinical and translational relevance of miR483-5p in adrenocortical cancer.

Salvianti F, Canu L, Poli G, Armignacco R, Scatena C, Cantini G, Di Franco A, Gelmini S, Ercolino T, Pazzagli M, Nesi G, Mannelli M, Pinzani P, Luconi M.

Oncotarget. 2017 Jul 10;8(39):65525-65533. doi: 10.18632/oncotarget.19118. eCollection 2017 Sep 12.

5.

DIAGNOSIS of ENDOCRINE DISEASE: SDHx mutations: beyond pheochromocytomas and paragangliomas.

Mannelli M, Canu L, Ercolino T, Rapizzi E, Martinelli S, Parenti G, De Filpo G, Nesi G.

Eur J Endocrinol. 2018 Jan;178(1):R11-R17. doi: 10.1530/EJE-17-0523. Epub 2017 Sep 18. Review.

PMID:
28924001
6.

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics.

Currás-Freixes M, Piñeiro-Yañez E, Montero-Conde C, Apellániz-Ruiz M, Calsina B, Mancikova V, Remacha L, Richter S, Ercolino T, Rogowski-Lehmann N, Deutschbein T, Calatayud M, Guadalix S, Álvarez-Escolá C, Lamas C, Aller J, Sastre-Marcos J, Lázaro C, Galofré JC, Patiño-García A, Meoro-Avilés A, Balmaña-Gelpi J, De Miguel-Novoa P, Balbín M, Matías-Guiu X, Letón R, Inglada-Pérez L, Torres-Pérez R, Roldán-Romero JM, Rodríguez-Antona C, Fliedner SMJ, Opocher G, Pacak K, Korpershoek E, de Krijger RR, Vroonen L, Mannelli M, Fassnacht M, Beuschlein F, Eisenhofer G, Cascón A, Al-Shahrour F, Robledo M.

J Mol Diagn. 2017 Jul;19(4):575-588. doi: 10.1016/j.jmoldx.2017.04.009. Epub 2017 May 25.

7.

Potential Pitfalls of SDH Immunohistochemical Detection in Paragangliomas and Phaeochromocytomas Harbouring Germline SDHx Gene Mutation.

Santi R, Rapizzi E, Canu L, Ercolino T, Baroni G, Fucci R, Costa G, Mannelli M, Nesi G.

Anticancer Res. 2017 Feb;37(2):805-812.

PMID:
28179334
8.

Consensus Statement on next-generation-sequencing-based diagnostic testing of hereditary phaeochromocytomas and paragangliomas.

NGS in PPGL (NGSnPPGL) Study Group, Toledo RA, Burnichon N, Cascon A, Benn DE, Bayley JP, Welander J, Tops CM, Firth H, Dwight T, Ercolino T, Mannelli M, Opocher G, Clifton-Bligh R, Gimm O, Maher ER, Robledo M, Gimenez-Roqueplo AP, Dahia PL.

Nat Rev Endocrinol. 2017 Apr;13(4):233-247. doi: 10.1038/nrendo.2016.185. Epub 2016 Nov 18. Review.

9.

Sunitinib in the therapy of malignant paragangliomas: report on the efficacy in a SDHB mutation carrier and review of the literature.

Canu L, Pradella S, Rapizzi E, Fucci R, Valeri A, Briganti V, Giachè V, Parenti G, Ercolino T, Mannelli M.

Arch Endocrinol Metab. 2017 Jan-Feb;61(1):90-97. doi: 10.1590/2359-3997000000217. Epub 2016 Oct 10. Review.

10.

Oncogenic features of the bone morphogenic protein 7 (BMP7) in pheochromocytoma.

Leinhäuser I, Richter A, Lee M, Höfig I, Anastasov N, Fend F, Ercolino T, Mannelli M, Gimenez-Roqueplo AP, Robledo M, de Krijger R, Beuschlein F, Atkinson MJ, Pellegata NS.

Oncotarget. 2015 Nov 17;6(36):39111-26. doi: 10.18632/oncotarget.4912.

11.

15 YEARS OF PARAGANGLIOMA: Metabolism and pheochromocytoma/paraganglioma.

Mannelli M, Rapizzi E, Fucci R, Canu L, Ercolino T, Luconi M, Young WF Jr.

Endocr Relat Cancer. 2015 Aug;22(4):T83-90. doi: 10.1530/ERC-15-0215. Epub 2015 Jun 25. Review.

PMID:
26113605
12.

2D-DIGE proteomic analysis identifies new potential therapeutic targets for adrenocortical carcinoma.

Poli G, Ceni E, Armignacco R, Ercolino T, Canu L, Baroni G, Nesi G, Galli A, Mannelli M, Luconi M.

Oncotarget. 2015 Mar 20;6(8):5695-706.

13.

Dissecting the origin of inducible brown fat in adult humans through a novel adipose stem cell model from adipose tissue surrounding pheochromocytoma.

Di Franco A, Guasti D, Mazzanti B, Ercolino T, Francalanci M, Nesi G, Bani D, Forti G, Mannelli M, Valeri A, Luconi M.

J Clin Endocrinol Metab. 2014 Oct;99(10):E1903-12. doi: 10.1210/jc.2014-1431. Epub 2014 Jun 27.

PMID:
24971662
14.

Pitfalls in genetic analysis of pheochromocytomas/paragangliomas-case report.

Canu L, Rapizzi E, Zampetti B, Fucci R, Nesi G, Richter S, Qin N, Giachè V, Bergamini C, Parenti G, Valeri A, Ercolino T, Eisenhofer G, Mannelli M.

J Clin Endocrinol Metab. 2014 Jul;99(7):2321-6. doi: 10.1210/jc.2013-4453. Epub 2014 Apr 23.

PMID:
24758185
15.

Succinate dehydrogenase subunit B mutations modify human neuroblastoma cell metabolism and proliferation.

Rapizzi E, Ercolino T, Fucci R, Zampetti B, Felici R, Guasti D, Morandi A, Giannoni E, Giaché V, Bani D, Chiarugi A, Mannelli M.

Horm Cancer. 2014 Jun;5(3):174-84. doi: 10.1007/s12672-014-0172-3. Epub 2014 Mar 5.

PMID:
24595825
16.

Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes.

Ercolino T, Lai R, Giachè V, Melchionda S, Carella M, Delitala A, Mannelli M, Fanciulli G.

Gene. 2014 Feb 25;536(2):332-5. doi: 10.1016/j.gene.2013.12.003. Epub 2013 Dec 21.

PMID:
24361808
17.

Clinical relevance of phenotype/genotype correlations in the diagnosis and therapy of pheochromocytomas/paragangliomas.

Parenti G, Zampetti B, Rapizzi E, Ercolino T, Giachè V, Fucci R, Mannelli M.

Q J Nucl Med Mol Imaging. 2013 Jun;57(2):112-21. Review.

PMID:
23822988
18.

Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis.

Comino-Méndez I, de Cubas AA, Bernal C, Álvarez-Escolá C, Sánchez-Malo C, Ramírez-Tortosa CL, Pedrinaci S, Rapizzi E, Ercolino T, Bernini G, Bacca A, Letón R, Pita G, Alonso MR, Leandro-García LJ, Gómez-Graña A, Inglada-Pérez L, Mancikova V, Rodríguez-Antona C, Mannelli M, Robledo M, Cascón A.

Hum Mol Genet. 2013 Jun 1;22(11):2169-76. doi: 10.1093/hmg/ddt069. Epub 2013 Feb 14.

PMID:
23418310
19.

Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome.

Panizza E, Ercolino T, Mori L, Rapizzi E, Castellano M, Opocher G, Ferrero I, Neumann HP, Mannelli M, Goffrini P.

Hum Mol Genet. 2013 Feb 15;22(4):804-15. doi: 10.1093/hmg/dds487. Epub 2012 Nov 21.

PMID:
23175444
20.

Updated and new perspectives on diagnosis, prognosis, and therapy of malignant pheochromocytoma/paraganglioma.

Parenti G, Zampetti B, Rapizzi E, Ercolino T, Giachè V, Mannelli M.

J Oncol. 2012;2012:872713. doi: 10.1155/2012/872713. Epub 2012 Jul 17.

21.

Genetic-clinical profile of subjects with apparently sporadic extra-adrenal paragangliomas.

Ramundo V, Ercolino T, Faggiano A, Giachè V, Ragghianti B, Rapizzi E, Colao A, Mannelli M.

Front Endocrinol (Lausanne). 2012 May 18;3:65. doi: 10.3389/fendo.2012.00065. eCollection 2012.

22.

MAX mutations cause hereditary and sporadic pheochromocytoma and paraganglioma.

Burnichon N, Cascón A, Schiavi F, Morales NP, Comino-Méndez I, Abermil N, Inglada-Pérez L, de Cubas AA, Amar L, Barontini M, de Quirós SB, Bertherat J, Bignon YJ, Blok MJ, Bobisse S, Borrego S, Castellano M, Chanson P, Chiara MD, Corssmit EP, Giacchè M, de Krijger RR, Ercolino T, Girerd X, Gómez-García EB, Gómez-Graña A, Guilhem I, Hes FJ, Honrado E, Korpershoek E, Lenders JW, Letón R, Mensenkamp AR, Merlo A, Mori L, Murat A, Pierre P, Plouin PF, Prodanov T, Quesada-Charneco M, Qin N, Rapizzi E, Raymond V, Reisch N, Roncador G, Ruiz-Ferrer M, Schillo F, Stegmann AP, Suarez C, Taschin E, Timmers HJ, Tops CM, Urioste M, Beuschlein F, Pacak K, Mannelli M, Dahia PL, Opocher G, Eisenhofer G, Gimenez-Roqueplo AP, Robledo M.

Clin Cancer Res. 2012 May 15;18(10):2828-37. doi: 10.1158/1078-0432.CCR-12-0160. Epub 2012 Mar 27.

23.

Mitochondrial function and content in pheochromocytoma/paraganglioma of succinate dehydrogenase mutation carriers.

Rapizzi E, Ercolino T, Canu L, Giaché V, Francalanci M, Pratesi C, Valeri A, Mannelli M.

Endocr Relat Cancer. 2012 May 3;19(3):261-9. doi: 10.1530/ERC-11-0263. Print 2012 Jun.

PMID:
22323561
24.

Head and neck paragangliomas: genetic spectrum and clinical variability in 79 consecutive patients.

Piccini V, Rapizzi E, Bacca A, Di Trapani G, Pulli R, Giachè V, Zampetti B, Lucci-Cordisco E, Canu L, Corsini E, Faggiano A, Deiana L, Carrara D, Tantardini V, Mariotti S, Ambrosio MR, Zatelli MC, Parenti G, Colao A, Pratesi C, Bernini G, Ercolino T, Mannelli M.

Endocr Relat Cancer. 2012 Apr 10;19(2):149-55. doi: 10.1530/ERC-11-0369. Print 2012 Apr.

PMID:
22241717
25.

Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas.

Yao L, Schiavi F, Cascon A, Qin Y, Inglada-Pérez L, King EE, Toledo RA, Ercolino T, Rapizzi E, Ricketts CJ, Mori L, Giacchè M, Mendola A, Taschin E, Boaretto F, Loli P, Iacobone M, Rossi GP, Biondi B, Lima-Junior JV, Kater CE, Bex M, Vikkula M, Grossman AB, Gruber SB, Barontini M, Persu A, Castellano M, Toledo SP, Maher ER, Mannelli M, Opocher G, Robledo M, Dahia PL.

JAMA. 2010 Dec 15;304(23):2611-9. doi: 10.1001/jama.2010.1830.

PMID:
21156949
26.

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma.

Molatore S, Liyanarachchi S, Irmler M, Perren A, Mannelli M, Ercolino T, Beuschlein F, Jarzab B, Wloch J, Ziaja J, Zoubaa S, Neff F, Beckers J, Höfler H, Atkinson MJ, Pellegata NS.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18493-8. doi: 10.1073/pnas.1003956107. Epub 2010 Oct 11.

27.

Role of the PPAR-γ system in normal and tumoral pituitary corticotropic cells and adrenal cells.

Mannelli M, Cantini G, Poli G, Mangoni M, Nesi G, Canu L, Rapizzi E, Borgogni E, Ercolino T, Piccini V, Luconi M.

Neuroendocrinology. 2010;92 Suppl 1:23-7. doi: 10.1159/000314312. Epub 2010 Sep 10. Review.

28.

Rosiglitazone impairs proliferation of human adrenocortical cancer: preclinical study in a xenograft mouse model.

Luconi M, Mangoni M, Gelmini S, Poli G, Nesi G, Francalanci M, Pratesi N, Cantini G, Lombardi A, Pepi M, Ercolino T, Serio M, Orlando C, Mannelli M.

Endocr Relat Cancer. 2010 Feb 18;17(1):169-77. doi: 10.1677/ERC-09-0170. Print 2010 Mar.

PMID:
19955217
29.

Occurrence of medullary thyroid carcinoma, bronchial carcinoid tumor, and papillary thyroid carcinoma in a family bearing the RET G691S polymorphism.

Rotondi M, Ercolino T, Fonte R, Lagonigro MS, Leporati P, Villani L, La Manna L, Mannelli M, Chiovato L.

J Endocrinol Invest. 2009 Feb;32(2):115-8.

PMID:
19411807
30.

Malignant extra-adrenal pheochromocytoma caused by an SDHB intronic variation leading to a 54-bp deletion in exon 4.

Ercolino T, Taurino C, Sestini R, Bacca AV, Genuardi M, Mannelli M, Bernini GP.

J Endocrinol Invest. 2009 Feb;32(2):111-4.

PMID:
19411806
31.

Functional study in a yeast model of a novel succinate dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor.

Goffrini P, Ercolino T, Panizza E, Giachè V, Cavone L, Chiarugi A, Dima V, Ferrero I, Mannelli M.

Hum Mol Genet. 2009 May 15;18(10):1860-8. doi: 10.1093/hmg/ddp102. Epub 2009 Mar 4.

PMID:
19261679
32.

Clinically guided genetic screening in a large cohort of italian patients with pheochromocytomas and/or functional or nonfunctional paragangliomas.

Mannelli M, Castellano M, Schiavi F, Filetti S, Giacchè M, Mori L, Pignataro V, Bernini G, Giachè V, Bacca A, Biondi B, Corona G, Di Trapani G, Grossrubatscher E, Reimondo G, Arnaldi G, Giacchetti G, Veglio F, Loli P, Colao A, Ambrosio MR, Terzolo M, Letizia C, Ercolino T, Opocher G; Italian Pheochromocytoma/Paraganglioma Network.

J Clin Endocrinol Metab. 2009 May;94(5):1541-7. doi: 10.1210/jc.2008-2419. Epub 2009 Feb 17.

33.

Rosiglitazone inhibits adrenocortical cancer cell proliferation by interfering with the IGF-IR intracellular signaling.

Cantini G, Lombardi A, Piscitelli E, Poli G, Ceni E, Marchiani S, Ercolino T, Galli A, Serio M, Mannelli M, Luconi M.

PPAR Res. 2008;2008:904041. doi: 10.1155/2008/904041. Epub 2008 Jul 28.

34.

The Y606C RET mutation causes a receptor gain of function.

Ercolino T, Lombardi A, Becherini L, Piscitelli E, Cantini G, Gaglianò MS, Serio M, Luconi M, Mannelli M.

Clin Endocrinol (Oxf). 2008 Aug;69(2):253-8. doi: 10.1111/j.1365-2265.2008.03197.x. Epub 2008 Jan 31.

PMID:
18248647
35.

Uncommon clinical presentations of pheochromocytoma and paraganglioma in two different patients affected by two distinct novel VHL germline mutations.

Ercolino T, Becherini L, Valeri A, Maiello M, Gaglianò MS, Parenti G, Ramazzotti M, Piscitelli E, Simi L, Pinzani P, Nesi G, Degl'Innocenti D, Console N, Bergamini C, Mannelli M.

Clin Endocrinol (Oxf). 2008 May;68(5):762-8. Epub 2007 Nov 19.

PMID:
18031321
36.

Genetic screening for pheochromocytoma: should SDHC gene analysis be included?

Mannelli M, Ercolino T, Giachè V, Simi L, Cirami C, Parenti G.

J Med Genet. 2007 Sep;44(9):586-7. Epub 2007 Jun 8.

37.

Genetics and biology of pheochromocytoma.

Mannelli M, Simi L, Gaglianò MS, Opocher G, Ercolino T, Becherini L, Parenti G.

Exp Clin Endocrinol Diabetes. 2007 Mar;115(3):160-5. Review.

PMID:
17427103
38.

SDH mutations in patients affected by paraganglioma syndromes: a personal experience.

Mannelli M, Simi L, Ercolino T, Gaglianò MS, Becherini L, Vinci S, Sestini R, Gensini F, Pinzani P, Mascalchi M, Guerrini L, Pratesi C, Nesi G, Torti F, Cipollini F, Bernini GP, Genuardi M.

Ann N Y Acad Sci. 2006 Aug;1073:183-9.

PMID:
17102085
39.

Unique association of non-functioning pheochromocytoma, ganglioneuroma, adrenal cortical adenoma, hepatic and vertebral hemangiomas in a patient with a new intronic variant in the VHL gene.

Bernini GP, Moretti A, Mannelli M, Ercolino T, Bardini M, Caramella D, Taurino C, Salvetti A.

J Endocrinol Invest. 2005 Dec;28(11):1032-7.

PMID:
16483185
40.

Phenotype variability of neural crest derived tumours in six Italian families segregating the same founder SDHD mutation Q109X.

Simi L, Sestini R, Ferruzzi P, Gaglianò MS, Gensini F, Mascalchi M, Guerrini L, Pratesi C, Pinzani P, Nesi G, Ercolino T, Genuardi M, Mannelli M.

J Med Genet. 2005 Aug;42(8):e52.

41.

Lack of evidence for interaction between APM1 and PPARgamma2 genes in modulating insulin sensitivity in nondiabetic Caucasians from Italy.

Menzaghi C, Ercolino T, Salvemini L, Coco A, Fini G, Di Paola R, Doria A, Trischitta V.

J Intern Med. 2005 Mar;257(3):315-7. No abstract available.

42.

The +276 G/T single nucleotide polymorphism of the adiponectin gene is associated with coronary artery disease in type 2 diabetic patients.

Bacci S, Menzaghi C, Ercolino T, Ma X, Rauseo A, Salvemini L, Vigna C, Fanelli R, Di Mario U, Doria A, Trischitta V.

Diabetes Care. 2004 Aug;27(8):2015-20.

PMID:
15277433
43.

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.

Menzaghi C, Ercolino T, Salvemini L, Coco A, Kim SH, Fini G, Doria A, Trischitta V.

Physiol Genomics. 2004 Oct 4;19(2):170-4. Epub 2004 Jul 13.

PMID:
15252189
44.

Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23.

Kim SH, Ma X, Weremowicz S, Ercolino T, Powers C, Mlynarski W, Bashan KA, Warram JH, Mychaleckyj J, Rich SS, Krolewski AS, Doria A.

Diabetes. 2004 May;53(5):1375-84.

45.

Insulin modulates PC-1 processing and recruitment in cultured human cells.

Menzaghi C, Di Paola R, Baj G, Funaro A, Arnulfo A, Ercolino T, Surico N, Malavasi F, Trischitta V.

Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E514-20. Epub 2002 Nov 19.

46.

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome.

Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A.

Diabetes. 2002 Jul;51(7):2306-12.

47.

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance.

Di Paola R, Frittitta L, Miscio G, Bozzali M, Baratta R, Centra M, Spampinato D, Santagati MG, Ercolino T, Cisternino C, Soccio T, Mastroianno S, Tassi V, Almgren P, Pizzuti A, Vigneri R, Trischitta V.

Am J Hum Genet. 2002 Mar;70(3):806-12. Epub 2002 Feb 6. Erratum in: Am J Hum Genet 2002 May;70(5):1388.

48.

A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities.

Frittitta L, Ercolino T, Bozzali M, Argiolas A, Graci S, Santagati MG, Spampinato D, Di Paola R, Cisternino C, Tassi V, Vigneri R, Pizzuti A, Trischitta V.

Diabetes. 2001 Aug;50(8):1952-5.

49.

High insulin levels do not influence PC-1 gene expression and protein content in human muscle tissue and hepatoma cells.

Frittitta L, Sbraccia P, Costanzo BV, Tassi V, D'Adamo M, Spampinato D, Ercolino T, Purrello F, Tamburrano G, Vigneri R, Trischitta V.

Diabetes Metab Res Rev. 2000 Jan-Feb;16(1):26-32.

PMID:
10707036
50.

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance.

Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine ID, Bozzali M, Ercolino T, Scarlato G, Iacoviello L, Vigneri R, Tassi V, Trischitta V.

Diabetes. 1999 Sep;48(9):1881-4.

PMID:
10480624

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