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Items: 9

1.

PI3Kβ is selectively required for growth factor-stimulated macropinocytosis.

Salloum G, Jakubik CT, Erami Z, Heitz SD, Bresnick AR, Backer JM.

J Cell Sci. 2019 Aug 16;132(16). pii: jcs231639. doi: 10.1242/jcs.231639.

PMID:
31409694
2.

PI3Kβ links integrin activation and PI(3,4)P2 production during invadopodial maturation.

Erami Z, Heitz S, Bresnick AR, Backer JM.

Mol Biol Cell. 2019 Aug 15;30(18):2367-2376. doi: 10.1091/mbc.E19-03-0182. Epub 2019 Jul 18.

PMID:
31318314
3.

A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion.

Heitz SD, Hamelin DJ, Hoffmann RM, Greenberg N, Salloum G, Erami Z, Khalil BD, Shymanets A, Steidle EA, Gong GQ, Nürnberg B, Burke JE, Flanagan JU, Bresnick AR, Backer JM.

J Biol Chem. 2019 Mar 22;294(12):4621-4633. doi: 10.1074/jbc.RA118.006032. Epub 2019 Jan 18.

PMID:
30659094
4.

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM.

Biochem J. 2017 Nov 16;474(23):3903-3914. doi: 10.1042/BCJ20170279.

5.

In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability.

Patella F, Neilson LJ, Athineos D, Erami Z, Anderson KI, Blyth K, Ryan KM, Zanivan S.

J Proteome Res. 2016 Jul 1;15(7):2187-97. doi: 10.1021/acs.jproteome.6b00166. Epub 2016 Jun 15.

PMID:
27246970
6.

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue.

Erami Z, Herrmann D, Warren SC, Nobis M, McGhee EJ, Lucas MC, Leung W, Reischmann N, Mrowinska A, Schwarz JP, Kadir S, Conway JRW, Vennin C, Karim SA, Campbell AD, Gallego-Ortega D, Magenau A, Murphy KJ, Ridgway RA, Law AM, Walters SN, Grey ST, Croucher DR, Zhang L, Herzog H, Hardeman EC, Gunning PW, Ormandy CJ, Evans TRJ, Strathdee D, Sansom OJ, Morton JP, Anderson KI, Timpson P.

Cell Rep. 2016 Jan 5;14(1):152-167. doi: 10.1016/j.celrep.2015.12.020. Epub 2015 Dec 24.

7.

There are four dynamically and functionally distinct populations of E-cadherin in cell junctions.

Erami Z, Timpson P, Yao W, Zaidel-Bar R, Anderson KI.

Biol Open. 2015 Oct 15;4(11):1481-9. doi: 10.1242/bio.014159.

8.

Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.

Patella F, Schug ZT, Persi E, Neilson LJ, Erami Z, Avanzato D, Maione F, Hernandez-Fernaud JR, Mackay G, Zheng L, Reid S, Frezza C, Giraudo E, Fiorio Pla A, Anderson K, Ruppin E, Gottlieb E, Zanivan S.

Mol Cell Proteomics. 2015 Mar;14(3):621-34. doi: 10.1074/mcp.M114.045575. Epub 2015 Jan 8.

9.

Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context.

Timpson P, McGhee EJ, Erami Z, Nobis M, Quinn JA, Edward M, Anderson KI.

J Vis Exp. 2011 Oct 13;(56):e3089. doi: 10.3791/3089.

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