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Items: 1 to 50 of 79

1.

Activin Is Superior to BMP7 for Efficient Maintenance of Human iPSC-Derived Nephron Progenitors.

Tanigawa S, Naganuma H, Kaku Y, Era T, Sakuma T, Yamamoto T, Taguchi A, Nishinakamura R.

Stem Cell Reports. 2019 Aug 13;13(2):322-337. doi: 10.1016/j.stemcr.2019.07.003. Epub 2019 Aug 1.

2.

Presynaptic Dysfunction in Neurons Derived from Tay-Sachs iPSCs.

Matsushita K, Numakawa T, Odaka H, Kajihara R, Soga M, Ozasa S, Nakamura K, Mizuta H, Era T.

Neuroscience. 2019 Aug 21;414:128-140. doi: 10.1016/j.neuroscience.2019.06.026. Epub 2019 Jul 5.

3.

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease.

Maeda Y, Motoyama K, Nishiyama R, Higashi T, Onodera R, Nakamura H, Takeo T, Nakagata N, Yamada Y, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Nanomaterials (Basel). 2019 May 25;9(5). pii: E802. doi: 10.3390/nano9050802.

4.

Simplifying the Chemical Structure of Cationic Lipids for siRNA-Lipid Nanoparticles.

Kuboyama T, Yagi K, Naoi T, Era T, Yagi N, Nakasato Y, Yabuuchi H, Takahashi S, Shinohara F, Iwai H, Koubara-Yamada A, Hasegawa K, Miwa A.

ACS Med Chem Lett. 2019 Apr 12;10(5):749-753. doi: 10.1021/acsmedchemlett.8b00652. eCollection 2019 May 9.

PMID:
31097994
5.

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes.

Tanigawa S, Islam M, Sharmin S, Naganuma H, Yoshimura Y, Haque F, Era T, Nakazato H, Nakanishi K, Sakuma T, Yamamoto T, Kurihara H, Taguchi A, Nishinakamura R.

Stem Cell Reports. 2018 Sep 11;11(3):727-740. doi: 10.1016/j.stemcr.2018.08.003. Epub 2018 Aug 30.

6.

Mesenchymal stem cells derived from human iPS cells via mesoderm and neuroepithelium have different features and therapeutic potentials.

Eto S, Goto M, Soga M, Kaneko Y, Uehara Y, Mizuta H, Era T.

PLoS One. 2018 Jul 25;13(7):e0200790. doi: 10.1371/journal.pone.0200790. eCollection 2018.

7.

Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.

Shioda N, Yabuki Y, Yamaguchi K, Onozato M, Li Y, Kurosawa K, Tanabe H, Okamoto N, Era T, Sugiyama H, Wada T, Fukunaga K.

Nat Med. 2018 Jun;24(6):802-813. doi: 10.1038/s41591-018-0018-6. Epub 2018 May 21.

PMID:
29785027
8.
9.

Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency.

Ito N, Katoh K, Kushige H, Saito Y, Umemoto T, Matsuzaki Y, Kiyonari H, Kobayashi D, Soga M, Era T, Araki N, Furuta Y, Suda T, Kida Y, Ohta K.

Sci Rep. 2018 Jan 26;8(1):1634. doi: 10.1038/s41598-018-20057-1.

10.

A Skeletal Muscle Model of Infantile-onset Pompe Disease with Patient-specific iPS Cells.

Yoshida T, Awaya T, Jonouchi T, Kimura R, Kimura S, Era T, Heike T, Sakurai H.

Sci Rep. 2017 Oct 18;7(1):13473. doi: 10.1038/s41598-017-14063-y.

11.

Impact of the Niemann-Pick c1 Gene Mutation on the Total Cellular Glycomics of CHO Cells.

Furukawa JI, Soga M, Okada K, Yokota I, Piao J, Irie T, Era T, Shinohara Y.

J Proteome Res. 2017 Aug 4;16(8):2802-2810. doi: 10.1021/acs.jproteome.7b00070. Epub 2017 Jul 3.

PMID:
28628327
12.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

13.

Synthesis of multi-lactose-appended β-cyclodextrin and its cholesterol-lowering effects in Niemann-Pick type C disease-like HepG2 cells.

Motoyama K, Nishiyama R, Maeda Y, Higashi T, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Beilstein J Org Chem. 2017 Jan 3;13:10-18. doi: 10.3762/bjoc.13.2. eCollection 2017.

14.
15.

Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos.

Masaki H, Kato-Itoh M, Takahashi Y, Umino A, Sato H, Ito K, Yanagida A, Nishimura T, Yamaguchi T, Hirabayashi M, Era T, Loh KM, Wu SM, Weissman IL, Nakauchi H.

Cell Stem Cell. 2016 Nov 3;19(5):587-592. doi: 10.1016/j.stem.2016.10.013.

16.

Cholesterol-Lowering Effect of Octaarginine-Appended β-Cyclodextrin in Npc1-Trap-CHO Cells.

Motoyama K, Nishiyama R, Maeda Y, Higashi T, Kawaguchi Y, Futaki S, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Biol Pharm Bull. 2016 Nov 1;39(11):1823-1829. Epub 2016 Sep 6.

17.

Cellular Functions and Gene and Protein Expression Profiles in Endothelial Cells Derived from Moyamoya Disease-Specific iPS Cells.

Hamauchi S, Shichinohe H, Uchino H, Yamaguchi S, Nakayama N, Kazumata K, Osanai T, Abumiya T, Houkin K, Era T.

PLoS One. 2016 Sep 23;11(9):e0163561. doi: 10.1371/journal.pone.0163561. eCollection 2016.

18.

Erratum to: Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.

Kondo T, Funayama M, Miyake M, Tsukita K, Era T, Osaka H, Ayaki T, Takahashi R, Inoue H.

Acta Neuropathol Commun. 2016 Sep 16;4(1):101. No abstract available.

19.

Establishment and gene expression analysis of disease-derived induced pluripotent stem cells of scleroderma.

Wang Z, Nakamura K, Jinnin M, Kudo H, Goto M, Era T, Kira T, Nakashima T, Fukushima S, Ihn H.

J Dermatol Sci. 2016 Nov;84(2):186-196. doi: 10.1016/j.jdermsci.2016.08.002. Epub 2016 Aug 2.

PMID:
27510999
20.

Modeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.

Kondo T, Funayama M, Miyake M, Tsukita K, Era T, Osaka H, Ayaki T, Takahashi R, Inoue H.

Acta Neuropathol Commun. 2016 Jul 11;4(1):69. doi: 10.1186/s40478-016-0337-0. Erratum in: Acta Neuropathol Commun. 2016;4(1):101.

21.

Cholesterol lowering effects of mono-lactose-appended β-cyclodextrin in Niemann-Pick type C disease-like HepG2 cells.

Motoyama K, Hirai Y, Nishiyama R, Maeda Y, Higashi T, Ishitsuka Y, Kondo Y, Irie T, Era T, Arima H.

Beilstein J Org Chem. 2015 Nov 3;11:2079-86. doi: 10.3762/bjoc.11.224. eCollection 2015.

22.

Disease modeling and lentiviral gene transfer in patient-specific induced pluripotent stem cells from late-onset Pompe disease patient.

Sato Y, Kobayashi H, Higuchi T, Shimada Y, Era T, Kimura S, Eto Y, Ida H, Ohashi T.

Mol Ther Methods Clin Dev. 2015 Jul 8;2:15023. doi: 10.1038/mtm.2015.23. eCollection 2015.

23.

Aloe vera Extract Suppresses Proliferation of Neuroblastoma Cells In Vitro.

Yonehara A, Tanaka Y, Kulkeaw K, Era T, Nakanishi Y, Sugiyama D.

Anticancer Res. 2015 Aug;35(8):4479-85.

PMID:
26168490
24.

Generation and characterization of PDGFRα-GFPCreERT2 knock-In mouse line.

Miwa H, Era T.

Genesis. 2015 May;53(5):329-36. doi: 10.1002/dvg.22853. Epub 2015 May 12.

PMID:
25884589
25.

Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients.

Maeda Y, Motoyama K, Higashi T, Horikoshi Y, Takeo T, Nakagata N, Kurauchi Y, Katsuki H, Ishitsuka Y, Kondo Y, Irie T, Furuya H, Era T, Arima H.

J Pharm Pharmacol. 2015 Aug;67(8):1133-42. doi: 10.1111/jphp.12405. Epub 2015 Apr 7.

PMID:
25851126
26.

HPGCD outperforms HPBCD as a potential treatment for Niemann-Pick disease type C during disease modeling with iPS cells.

Soga M, Ishitsuka Y, Hamasaki M, Yoneda K, Furuya H, Matsuo M, Ihn H, Fusaki N, Nakamura K, Nakagata N, Endo F, Irie T, Era T.

Stem Cells. 2015 Apr;33(4):1075-88. doi: 10.1002/stem.1917. Erratum in: Stem Cells. 2015 Sep;33(9):2885-6.

27.

Mesoderm Differentiation from hiPS Cells.

Miwa H, Era T.

Methods Mol Biol. 2016;1357:403-13. doi: 10.1007/7651_2014_162.

PMID:
25520286
28.

New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood.

Fujie Y, Fusaki N, Katayama T, Hamasaki M, Soejima Y, Soga M, Ban H, Hasegawa M, Yamashita S, Kimura S, Suzuki S, Matsuzawa T, Akari H, Era T.

PLoS One. 2014 Dec 5;9(12):e113052. doi: 10.1371/journal.pone.0113052. eCollection 2014.

29.

Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells.

Isono K, Jono H, Ohya Y, Shiraki N, Yamazoe T, Sugasaki A, Era T, Fusaki N, Tasaki M, Ueda M, Shinriki S, Inomata Y, Kume S, Ando Y.

Stem Cell Res. 2014 Mar;12(2):574-83. doi: 10.1016/j.scr.2014.01.004. Epub 2014 Jan 27.

30.

Ectopic cerebellar cell migration causes maldevelopment of Purkinje cells and abnormal motor behaviour in Cxcr4 null mice.

Huang GJ, Edwards A, Tsai CY, Lee YS, Peng L, Era T, Hirabayashi Y, Tsai CY, Nishikawa S, Iwakura Y, Chen SJ, Flint J.

PLoS One. 2014 Feb 7;9(2):e86471. doi: 10.1371/journal.pone.0086471. eCollection 2014.

31.

Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro.

Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe K, Kimura E, Sakurai H.

PLoS One. 2013 Apr 23;8(4):e61540. doi: 10.1371/journal.pone.0061540. Print 2013.

32.

Dual origin of melanocytes defined by Sox1 expression and their region-specific distribution in mammalian skin.

Yoshimura N, Motohashi T, Aoki H, Tezuka K, Watanabe N, Wakaoka T, Era T, Kunisada T.

Dev Growth Differ. 2013 Feb;55(2):270-81. doi: 10.1111/dgd.12034. Epub 2013 Jan 24.

PMID:
23347447
33.

Pathogenic mutation of ALK2 inhibits induced pluripotent stem cell reprogramming and maintenance: mechanisms of reprogramming and strategy for drug identification.

Hamasaki M, Hashizume Y, Yamada Y, Katayama T, Hohjoh H, Fusaki N, Nakashima Y, Furuya H, Haga N, Takami Y, Era T.

Stem Cells. 2012 Nov;30(11):2437-49. doi: 10.1002/stem.1221.

34.

Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-α.

Kitagawa M, Takebe A, Ono Y, Imai T, Nakao K, Nishikawa S, Era T.

J Biol Chem. 2012 Aug 10;287(33):27983-96. doi: 10.1074/jbc.M112.350074. Epub 2012 Jun 23.

35.

Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis.

Aoki H, Hara A, Era T, Kunisada T, Yamada Y.

Development. 2012 Feb;139(4):667-77. doi: 10.1242/dev.072272. Epub 2012 Jan 12.

36.

Mesoderm cell development from ES cells.

Era T.

Methods Mol Biol. 2010;636:87-103. doi: 10.1007/978-1-60761-691-7_6.

PMID:
20336518
37.

Differentiation of mesodermal cells from pluripotent stem cells.

Kitagawa M, Era T.

Int J Hematol. 2010 Apr;91(3):373-83. doi: 10.1007/s12185-010-0518-8. Epub 2010 Mar 12. Review.

PMID:
20224874
38.

Pax6-5a promotes neuronal differentiation of murine embryonic stem cells.

Shimizu N, Watanabe H, Kubota J, Wu J, Saito R, Yokoi T, Era T, Iwatsubo T, Watanabe T, Nishina S, Azuma N, Katada T, Nishina H.

Biol Pharm Bull. 2009 Jun;32(6):999-1003.

39.

The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.

Kinoshita M, Era T, Jakt LM, Nishikawa S.

Development. 2009 Jun;136(12):2069-79. doi: 10.1242/dev.026435.

40.

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.

Arnold SJ, Huang GJ, Cheung AF, Era T, Nishikawa S, Bikoff EK, Molnár Z, Robertson EJ, Groszer M.

Genes Dev. 2008 Sep 15;22(18):2479-84. doi: 10.1101/gad.475408.

41.

AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells.

Satoh Y, Matsumura I, Tanaka H, Ezoe S, Fukushima K, Tokunaga M, Yasumi M, Shibayama H, Mizuki M, Era T, Okuda T, Kanakura Y.

J Biol Chem. 2008 Oct 31;283(44):30045-56. doi: 10.1074/jbc.M804768200. Epub 2008 Aug 7.

42.

[Origin of mesenchymal stem cells].

Era T, Takashima Y, Nishikawa S.

Tanpakushitsu Kakusan Koso. 2008 Jan;53(1):59-64. Review. Japanese. No abstract available.

PMID:
18186304
43.
44.

Total synthesis of (+/-)-gleenol and (+/-)-axenol via a functionalized spiro[4.5]decane.

Nakazaki A, Era T, Kobayashi S.

Chem Pharm Bull (Tokyo). 2007 Nov;55(11):1606-9.

45.

Neuroepithelial cells supply an initial transient wave of MSC differentiation.

Takashima Y, Era T, Nakao K, Kondo S, Kasuga M, Smith AG, Nishikawa S.

Cell. 2007 Jun 29;129(7):1377-88.

46.

Embryonic stem-cell culture as a tool for developmental cell biology.

Nishikawa S, Jakt LM, Era T.

Nat Rev Mol Cell Biol. 2007 Jun;8(6):502-7. doi: 10.1038/nrm2189. Review.

PMID:
17522593
47.

Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference.

Izumi N, Era T, Akimaru H, Yasunaga M, Nishikawa S.

Stem Cells. 2007 Jul;25(7):1664-74. Epub 2007 Apr 19.

48.

Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.

Tanaka Y, Era T, Nishikawa S, Kawamata S.

Blood. 2007 Jul 1;110(1):107-15. Epub 2007 Mar 14.

PMID:
17360937
49.

Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model.

Kometani K, Aoki M, Kawamata S, Shinozuka Y, Era T, Taniwaki M, Hattori M, Minato N.

Cancer Res. 2006 Oct 15;66(20):9967-76.

50.

ARID3B induces malignant transformation of mouse embryonic fibroblasts and is strongly associated with malignant neuroblastoma.

Kobayashi K, Era T, Takebe A, Jakt LM, Nishikawa S.

Cancer Res. 2006 Sep 1;66(17):8331-6.

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