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Items: 18

1.

Phase 1-2 study of vorinostat (SAHA), cladribine and rituximab (SCR) in relapsed B-cell non-Hodgkin lymphoma and previously untreated mantle cell lymphoma.

Spurgeon SE, Sharma K, Claxton DF, Ehmann C, Pu J, Shimko S, Stewart A, Subbiah N, Palmbach G, LeBlanc F, Latour E, Chen Y, Mori M, Hasanali Z, Epner EM.

Br J Haematol. 2019 Sep;186(6):845-854. doi: 10.1111/bjh.16008. Epub 2019 Jun 9.

PMID:
31177537
2.

Mantle cell lymphoma and its management: where are we now?

Ladha A, Zhao J, Epner EM, Pu JJ.

Exp Hematol Oncol. 2019 Jan 30;8:2. doi: 10.1186/s40164-019-0126-0. eCollection 2019. Review.

3.

Combination epigenetic and immunotherapy overcomes resistance to monoclonal antibodies in hematologic malignancies: A new therapeutic approach.

Epner EM, Saroya BS, Hasanali ZS, Loughran TP Jr.

Exp Hematol. 2016 Mar;44(3):157-60. doi: 10.1016/j.exphem.2015.12.011. Epub 2016 Jan 21. Review.

PMID:
26802532
4.

Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia.

Hasanali ZS, Saroya BS, Stuart A, Shimko S, Evans J, Vinod Shah M, Sharma K, Leshchenko VV, Parekh S, Loughran TP Jr, Epner EM.

Sci Transl Med. 2015 Jun 24;7(293):293ra102. doi: 10.1126/scitranslmed.aaa5079.

5.

Vorinostat downregulates CD30 and decreases brentuximab vedotin efficacy in human lymphocytes.

Hasanali ZS, Epner EM, Feith DJ, Loughran TP Jr, Sample CE.

Mol Cancer Ther. 2014 Dec;13(12):2784-92. doi: 10.1158/1535-7163.MCT-14-0593. Epub 2014 Oct 15.

6.

Current approaches to epigenetic therapy for the treatment of mantle cell lymphoma.

Ghai V, Sharma K, Abbi KK, Shimko S, Epner EM.

Adv Exp Med Biol. 2013;779:257-66. doi: 10.1007/978-1-4614-6176-0_11. Review.

PMID:
23288643
7.

Cladribine plus rituximab is an effective therapy for newly diagnosed mantle cell lymphoma.

Spurgeon SE, Pindyck T, Okada C, Chen Y, Chen Z, Mater E, Abbi K, Epner EM.

Leuk Lymphoma. 2011 Aug;52(8):1488-94. doi: 10.3109/10428194.2011.575489. Epub 2011 May 31.

PMID:
21623691
8.

Cladribine: not just another purine analogue?

Spurgeon S, Yu M, Phillips JD, Epner EM.

Expert Opin Investig Drugs. 2009 Aug;18(8):1169-81. doi: 10.1517/13543780903071038. Review.

PMID:
19604118
9.

Sox6 directly silences epsilon globin expression in definitive erythropoiesis.

Yi Z, Cohen-Barak O, Hagiwara N, Kingsley PD, Fuchs DA, Erickson DT, Epner EM, Palis J, Brilliant MH.

PLoS Genet. 2006 Feb;2(2):e14. Epub 2006 Feb 3.

10.

Targeted deletion of the chicken beta-globin regulatory elements reveals a cooperative gene silencing activity.

Wang J, Liu H, Lin CM, Aladjem MI, Epner EM.

J Biol Chem. 2005 Jun 17;280(24):23340-8. Epub 2005 Apr 11.

11.

Hematopoietic cell transplantation from HLA-identical sibling donors after low-dose radiation-based conditioning for treatment of CML.

Kerbauy FR, Storb R, Hegenbart U, Gooley T, Shizuru J, Al-Ali HK, Radich JP, Maloney DG, Agura E, Bruno B, Epner EM, Chauncey TR, Blume KG, Niederwieser D, Sandmaier BM.

Leukemia. 2005 Jun;19(6):990-7.

PMID:
15800667
13.

Replication initiation patterns in the beta-globin loci of totipotent and differentiated murine cells: evidence for multiple initiation regions.

Aladjem MI, Rodewald LW, Lin CM, Bowman S, Cimbora DM, Brody LL, Epner EM, Groudine M, Wahl GM.

Mol Cell Biol. 2002 Jan;22(2):442-52.

14.

Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region.

Cimbora DM, Schübeler D, Reik A, Hamilton J, Francastel C, Epner EM, Groudine M.

Mol Cell Biol. 2000 Aug;20(15):5581-91.

15.

Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids.

Dieken ES, Epner EM, Fiering S, Fournier RE, Groudine M.

Nat Genet. 1996 Feb;12(2):174-82.

PMID:
8563756
16.

Participation of the human beta-globin locus control region in initiation of DNA replication.

Aladjem MI, Groudine M, Brody LL, Dieken ES, Fournier RE, Wahl GM, Epner EM.

Science. 1995 Nov 3;270(5237):815-9.

PMID:
7481774
18.

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region.

Kim CG, Epner EM, Forrester WC, Groudine M.

Genes Dev. 1992 Jun;6(6):928-38.

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