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Items: 1 to 50 of 88


Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis.

Hampoelz B, Schwarz A, Ronchi P, Bragulat-Teixidor H, Tischer C, Gaspar I, Ephrussi A, Schwab Y, Beck M.

Cell. 2019 Oct 17;179(3):671-686.e17. doi: 10.1016/j.cell.2019.09.022.


Transcript specific mRNP capture from Drosophila egg-chambers for proteomic analysis.

Wippich F, Ephrussi A.

Methods. 2019 Sep 5. pii: S1046-2023(18)30489-4. doi: 10.1016/j.ymeth.2019.09.001. [Epub ahead of print]


Germ Cell Lineage Homeostasis in Drosophila Requires the Vasa RNA Helicase.

Durdevic Z, Ephrussi A.

Genetics. 2019 Nov;213(3):911-922. doi: 10.1534/genetics.119.302558. Epub 2019 Sep 4.


The Transcriptome-wide Landscape and Modalities of EJC Binding in Adult Drosophila.

Obrdlik A, Lin G, Haberman N, Ule J, Ephrussi A.

Cell Rep. 2019 Jul 30;28(5):1219-1236.e11. doi: 10.1016/j.celrep.2019.06.088.


Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains.

Heber S, Gáspár I, Tants JN, Günther J, Moya SMF, Janowski R, Ephrussi A, Sattler M, Niessing D.

Nat Commun. 2019 Apr 10;10(1):1659. doi: 10.1038/s41467-019-09655-3.


Transposon silencing in the Drosophila female germline is essential for genome stability in progeny embryos.

Durdevic Z, Pillai RS, Ephrussi A.

Life Sci Alliance. 2018 Sep 17;1(5):e201800179. doi: 10.26508/lsa.201800179. eCollection 2018 Oct.


Quantitative mRNA Imaging with Dual Channel qFIT Probes to Monitor Distribution and Degree of Hybridization.

Gaspar I, Hövelmann F, Chamiolo J, Ephrussi A, Seitz O.

ACS Chem Biol. 2018 Mar 16;13(3):742-749. doi: 10.1021/acschembio.7b01007. Epub 2018 Feb 7.


In Vivo Visualization and Function Probing of Transport mRNPs Using Injected FIT Probes.

Chamiolo J, Gaspar I, Ephrussi A, Seitz O.

Methods Mol Biol. 2018;1649:273-287. doi: 10.1007/978-1-4939-7213-5_18.


RNA localization feeds translation.

Gáspár I, Ephrussi A.

Science. 2017 Sep 22;357(6357):1235-1236. doi: 10.1126/science.aao5796. No abstract available.


Ex vivo Ooplasmic Extract from Developing Drosophila Oocytes for Quantitative TIRF Microscopy Analysis.

Gaspar I, Ephrussi A.

Bio Protoc. 2017 Jul 5;7(13). pii: e2380. doi: 10.21769/BioProtoc.2380.


Enzymatic production of single-molecule FISH and RNA capture probes.

Gaspar I, Wippich F, Ephrussi A.

RNA. 2017 Oct;23(10):1582-1591. doi: 10.1261/rna.061184.117. Epub 2017 Jul 11.


The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage.

Jeske M, Müller CW, Ephrussi A.

Genes Dev. 2017 May 1;31(9):939-952. doi: 10.1101/gad.297051.117. Epub 2017 May 23.


An RNA-binding atypical tropomyosin recruits kinesin-1 dynamically to oskar mRNPs.

Gáspár I, Sysoev V, Komissarov A, Ephrussi A.

EMBO J. 2017 Feb 1;36(3):319-333. doi: 10.15252/embj.201696038. Epub 2016 Dec 27.


Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila.

Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A.

Nat Commun. 2016 Jul 5;7:12128. doi: 10.1038/ncomms12128.


TRICK: A Single-Molecule Method for Imaging the First Round of Translation in Living Cells and Animals.

Halstead JM, Wilbertz JH, Wippich F, Lionnet T, Ephrussi A, Chao JA.

Methods Enzymol. 2016;572:123-57. doi: 10.1016/bs.mie.2016.02.027. Epub 2016 Apr 29.


CncRNAs: RNAs with both coding and non-coding roles in development.

Sampath K, Ephrussi A.

Development. 2016 Apr 15;143(8):1234-41. doi: 10.1242/dev.133298. Review.


LNA-enhanced DNA FIT-probes for multicolour RNA imaging.

Hövelmann F, Gaspar I, Chamiolo J, Kasper M, Steffen J, Ephrussi A, Seitz O.

Chem Sci. 2016 Jan 1;7(1):128-135. doi: 10.1039/c5sc03053f. Epub 2015 Nov 2.


The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities.

Jeske M, Bordi M, Glatt S, Müller S, Rybin V, Müller CW, Ephrussi A.

Cell Rep. 2015 Jul 28;12(4):587-98. doi: 10.1016/j.celrep.2015.06.055. Epub 2015 Jul 16.


The structure of the SOLE element of oskar mRNA.

Simon B, Masiewicz P, Ephrussi A, Carlomagno T.

RNA. 2015 Aug;21(8):1444-53. doi: 10.1261/rna.049601.115. Epub 2015 Jun 18.


oskar RNA plays multiple noncoding roles to support oogenesis and maintain integrity of the germline/soma distinction.

Kanke M, Jambor H, Reich J, Marches B, Gstir R, Ryu YH, Ephrussi A, Macdonald PM.

RNA. 2015 Jun;21(6):1096-109. doi: 10.1261/rna.048298.114. Epub 2015 Apr 10.


Translation. An RNA biosensor for imaging the first round of translation from single cells to living animals.

Halstead JM, Lionnet T, Wilbertz JH, Wippich F, Ephrussi A, Singer RH, Chao JA.

Science. 2015 Mar 20;347(6228):1367-671. doi: 10.1126/science.aaa3380.


Live imaging of axonal transport in Drosophila pupal brain explants.

Medioni C, Ephrussi A, Besse F.

Nat Protoc. 2015 Apr;10(4):574-84. doi: 10.1038/nprot.2015.034. Epub 2015 Mar 12.


Strength in numbers: quantitative single-molecule RNA detection assays.

Gaspar I, Ephrussi A.

Wiley Interdiscip Rev Dev Biol. 2015 Mar-Apr;4(2):135-50. doi: 10.1002/wdev.170. Epub 2015 Jan 21. Review.


Brightness through local constraint--LNA-enhanced FIT hybridization probes for in vivo ribonucleotide particle tracking.

Hövelmann F, Gaspar I, Loibl S, Ermilov EA, Röder B, Wengel J, Ephrussi A, Seitz O.

Angew Chem Int Ed Engl. 2014 Oct 13;53(42):11370-5. doi: 10.1002/anie.201406022. Epub 2014 Aug 28.


Considerations when investigating lncRNA function in vivo.

Bassett AR, Akhtar A, Barlow DP, Bird AP, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith AC, Gingeras TR, Haerty W, Higgs DR, Miska EA, Ponting CP.

Elife. 2014 Aug 14;3:e03058. doi: 10.7554/eLife.03058. Review.


Klar ensures thermal robustness of oskar localization by restraining RNP motility.

Gaspar I, Yu YV, Cotton SL, Kim DH, Ephrussi A, Welte MA.

J Cell Biol. 2014 Jul 21;206(2):199-215. doi: 10.1083/jcb.201310010.


The EJC binding and dissociating activity of PYM is regulated in Drosophila.

Ghosh S, Obrdlik A, Marchand V, Ephrussi A.

PLoS Genet. 2014 Jun 26;10(6):e1004455. doi: 10.1371/journal.pgen.1004455. eCollection 2014 Jun. Erratum in: PLoS Genet. 2015 Apr;11(4):e1005157.


RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.

Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, Kaksonen M, Cusack S, Ephrussi A, Pillai RS.

Cell. 2014 Jun 19;157(7):1698-711. doi: 10.1016/j.cell.2014.05.018. Epub 2014 Jun 5.


Imp promotes axonal remodeling by regulating profilin mRNA during brain development.

Medioni C, Ramialison M, Ephrussi A, Besse F.

Curr Biol. 2014 Mar 31;24(7):793-800. doi: 10.1016/j.cub.2014.02.038. Epub 2014 Mar 20.


A stem-loop structure directs oskar mRNA to microtubule minus ends.

Jambor H, Mueller S, Bullock SL, Ephrussi A.

RNA. 2014 Apr;20(4):429-39. doi: 10.1261/rna.041566.113. Epub 2014 Feb 26.


Brightness enhanced DNA FIT-probes for wash-free RNA imaging in tissue.

Hövelmann F, Gaspar I, Ephrussi A, Seitz O.

J Am Chem Soc. 2013 Dec 18;135(50):19025-32. doi: 10.1021/ja410674h. Epub 2013 Dec 10.


A single Drosophila embryo extract for the study of mitosis ex vivo.

Telley IA, Gáspár I, Ephrussi A, Surrey T.

Nat Protoc. 2013 Feb;8(2):310-24. doi: 10.1038/nprot.2013.003. Epub 2013 Jan 17.


A Cdc42-regulated actin cytoskeleton mediates Drosophila oocyte polarization.

Leibfried A, Müller S, Ephrussi A.

Development. 2013 Jan 15;140(2):362-71. doi: 10.1242/dev.089250.


Aster migration determines the length scale of nuclear separation in the Drosophila syncytial embryo.

Telley IA, Gáspár I, Ephrussi A, Surrey T.

J Cell Biol. 2012 Jun 25;197(7):887-95. doi: 10.1083/jcb.201204019. Epub 2012 Jun 18.


Control of RNP motility and localization by a splicing-dependent structure in oskar mRNA.

Ghosh S, Marchand V, Gáspár I, Ephrussi A.

Nat Struct Mol Biol. 2012 Mar 18;19(4):441-9. doi: 10.1038/nsmb.2257.


An intracellular transmission control protocol: assembly and transport of ribonucleoprotein complexes.

Marchand V, Gaspar I, Ephrussi A.

Curr Opin Cell Biol. 2012 Apr;24(2):202-10. doi: 10.1016/ Epub 2012 Jan 23. Review.


Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte.

Jambor H, Brunel C, Ephrussi A.

RNA. 2011 Dec;17(12):2049-57. doi: 10.1261/rna.2686411. Epub 2011 Oct 25.


Drosophila Ge-1 promotes P body formation and oskar mRNA localization.

Fan SJ, Marchand V, Ephrussi A.

PLoS One. 2011;6(5):e20612. doi: 10.1371/journal.pone.0020612. Epub 2011 May 31.


Retraction notice to: Assembly of endogenous oskar mRNA particles for motor-dependent transport in the Drosophila oocyte.

Trucco A, Gaspar I, Ephrussi A.

Cell. 2010 Oct 29;143(3):485. doi: 10.1016/j.cell.2010.10.011. No abstract available.


Assembly of endogenous oskar mRNA particles for motor-dependent transport in the Drosophila oocyte.

Trucco A, Gaspar I, Ephrussi A.

Cell. 2009 Nov 25;139(5):983-98. doi: 10.1016/j.cell.2009.10.012. Retraction in: Trucco A, Gaspar I, Ephrussi A. Cell. 2010 Oct 29;143(3):485.


Myosin-V regulates oskar mRNA localization in the Drosophila oocyte.

Krauss J, López de Quinto S, Nüsslein-Volhard C, Ephrussi A.

Curr Biol. 2009 Jun 23;19(12):1058-63. doi: 10.1016/j.cub.2009.04.062. Epub 2009 May 28.


mRNA localization: gene expression in the spatial dimension.

Martin KC, Ephrussi A.

Cell. 2009 Feb 20;136(4):719-30. doi: 10.1016/j.cell.2009.01.044. Review.


Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation.

Besse F, López de Quinto S, Marchand V, Trucco A, Ephrussi A.

Genes Dev. 2009 Jan 15;23(2):195-207. doi: 10.1101/gad.505709. Epub 2009 Jan 8.


Drosophila ensconsin promotes productive recruitment of Kinesin-1 to microtubules.

Sung HH, Telley IA, Papadaki P, Ephrussi A, Surrey T, Rørth P.

Dev Cell. 2008 Dec;15(6):866-76. doi: 10.1016/j.devcel.2008.10.006.


The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.

Suyama R, Jenny A, Curado S, Pellis-van Berkel W, Ephrussi A.

Development. 2009 Jan;136(1):95-105. doi: 10.1242/dev.027698. Epub 2008 Nov 26.


Translational control of localized mRNAs: restricting protein synthesis in space and time.

Besse F, Ephrussi A.

Nat Rev Mol Cell Biol. 2008 Dec;9(12):971-80. doi: 10.1038/nrm2548. Review.


The Ig cell adhesion molecule Basigin controls compartmentalization and vesicle release at Drosophila melanogaster synapses.

Besse F, Mertel S, Kittel RJ, Wichmann C, Rasse TM, Sigrist SJ, Ephrussi A.

J Cell Biol. 2007 Jun 4;177(5):843-55.


Stimulation of endocytosis and actin dynamics by Oskar polarizes the Drosophila oocyte.

Vanzo N, Oprins A, Xanthakis D, Ephrussi A, Rabouille C.

Dev Cell. 2007 Apr;12(4):543-55.


Rab6 mediates membrane organization and determinant localization during Drosophila oogenesis.

Coutelis JB, Ephrussi A.

Development. 2007 Apr;134(7):1419-30. Epub 2007 Feb 28.


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