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87 results

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EPB41 suppresses the Wnt/beta-catenin signaling in non-small cell lung cancer by sponging ALDOC.
Yuan J, Xing H, Li Y, Song Y, Zhang N, Xie M, Liu J, Xu Y, Shen Y, Wang B, Zhang L, Yang M. Yuan J, et al. Cancer Lett. 2021 Feb 28;499:255-264. doi: 10.1016/j.canlet.2020.11.024. Epub 2020 Nov 24. Cancer Lett. 2021. PMID: 33242559
Consistent with its tumor suppressor role in NSCLC, the expression of EPB41 in NSCLC specimens evidently decreased compared to that in normal tissues, and low EPB41 expression was associated with poor prognoses for NSCLC patients. ...Our study highlights the potenti …
Consistent with its tumor suppressor role in NSCLC, the expression of EPB41 in NSCLC specimens evidently decreased compared to that i …
Lnc-EPB41-Protein Interactions Associated with Congenital Pouch Colon.
Gupta S, Gupta N, Tiwari P, Menon S, Mathur P, Kothari SL, Nallapeta S, Medicherla KM, Suravajhala P. Gupta S, et al. Biomolecules. 2018 Sep 17;8(3):95. doi: 10.3390/biom8030095. Biomolecules. 2018. PMID: 30227690 Free PMC article.
Further screening and quantification using polymerase chain reaction (PCR), we ascertained interactions using Micro Scale Thermophoresis (MST). We report the role of lnc-EPB41-1-1 shown to be promiscuously interacting with KIF13A substantiating their role in regulation....
Further screening and quantification using polymerase chain reaction (PCR), we ascertained interactions using Micro Scale Thermophoresis (MS …
Circular RNA EPB41 expression predicts unfavorable prognoses in NSCLC by regulating miR-486-3p/eIF5A axis-mediated stemness.
Jin M, Liu X, Wu Y, Lou Y, Li X, Huang G. Jin M, et al. Cancer Cell Int. 2022 Jun 20;22(1):219. doi: 10.1186/s12935-022-02618-7. Cancer Cell Int. 2022. PMID: 35725615 Free PMC article.
The results show that the circ-EPB41 was upregulated in NSCLC tissues and cell lines. Increased circ-EPB41 expression in NSCLC was significantly correlated with malignant characteristics, and positive to post-surgical overall survival of NSCLC patients. Reduced circ …
The results show that the circ-EPB41 was upregulated in NSCLC tissues and cell lines. Increased circ-EPB41 expression in NSCLC …
Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion? Findings from the NCAA and Department of Defense CARE Consortium.
Vorn R, Devoto C, Meier TB, Lai C, Yun S, Broglio SP, Mithani S, McAllister TW, Giza CC, Kim HS, Huber D, Harezlak J, Cameron KL, McGinty G, Jackson J, Guskiewicz KM, Mihalik JP, Brooks A, Duma S, Rowson S, Nelson LD, Pasquina P, McCrea MA, Gill JM; CARE Consortium Investigators. Vorn R, et al. J Sport Health Sci. 2023 May;12(3):379-387. doi: 10.1016/j.jshs.2022.11.007. Epub 2022 Nov 18. J Sport Health Sci. 2023. PMID: 36403906 Free PMC article.
Specifically, after 6 h of injury, the individual AUC of plasma erythrocyte membrane protein band 4.1 (EPB41) and alpha-synuclein (SNCA) were 0.956 and 0.875, respectively. The combination of EPB41 and SNCA provided the best AUC (1.000), which suggests this combinat …
Specifically, after 6 h of injury, the individual AUC of plasma erythrocyte membrane protein band 4.1 (EPB41) and alpha-synuclein (SN …
Alternative polyadenylation in a family of paralogous EPB41 genes generates protein 4.1 diversity.
Rangel L, Lospitao E, Ruiz-Sáenz A, Alonso MA, Correas I. Rangel L, et al. RNA Biol. 2017 Feb;14(2):236-244. doi: 10.1080/15476286.2016.1270003. Epub 2016 Dec 16. RNA Biol. 2017. PMID: 27981895 Free PMC article.
For the EPB41 gene, this type of processing was observed in all 11 human tissues analyzed. Comparative genomic analysis of EPB41 indicates that APA is conserved in various mammals. In addition, we show that APA also functions for the EPB41L2, EPB41L3 and EPB41L1 gen …
For the EPB41 gene, this type of processing was observed in all 11 human tissues analyzed. Comparative genomic analysis of EPB41
Silencing EPB41 Gene Expression Leads to Cell Cycle Arrest, Migration Inhibition, and Upregulation of Cell Surface Antigen in DC2.4 Cells.
Zhao Q, Li Y, Li Y, Ji X, Li H, Wu D, Wei W, Xinchun W. Zhao Q, et al. Med Sci Monit. 2020 Mar 11;26:e920594. doi: 10.12659/MSM.920594. Med Sci Monit. 2020. PMID: 32157074 Free PMC article.
BACKGROUND Protein 4.1R (EPB41) is the main cytoskeleton component of the erythrocyte membrane and may be involved in cell migration and adhesion. ...
BACKGROUND Protein 4.1R (EPB41) is the main cytoskeleton component of the erythrocyte membrane and may be involved in cell migration …
A novel EPB41 p.Trp704* mutation in a Korean patient with hereditary elliptocytosis: a case report.
Shin S, Hwang KA, Paik K, Park J. Shin S, et al. Hematology. 2020 Dec;25(1):321-326. doi: 10.1080/16078454.2020.1807227. Hematology. 2020. PMID: 32807033
Targeted gene panel sequencing consisting of 33 genes related to inherited RBC disorders and Sanger sequencing were performed. Results: A heterozygous c.2112G > A of the EPB41 gene leading to premature termination codon (NM_001166005.1:c.2112G > A, p.Trp704*) was ide …
Targeted gene panel sequencing consisting of 33 genes related to inherited RBC disorders and Sanger sequencing were performed. Results: A he …
GADD45A and EPB41 as tumor suppressor genes in meningioma pathogenesis.
Piaskowski S, Rieske P, Szybka M, Wozniak K, Bednarek A, Płuciennik E, Jaskolski D, Sikorska B, Liberski PP. Piaskowski S, et al. Cancer Genet Cytogenet. 2005 Oct 1;162(1):63-7. doi: 10.1016/j.cancergencyto.2005.02.009. Cancer Genet Cytogenet. 2005. PMID: 16157202
We conclude that the GADD45A gene is not involved in meningioma tumorigenesis. EPB41 gene expression was unchanged in all analyzed meningiomas. This suggests that involvement of the EPB41 gene (4.1R protein) in meningioma pathogenesis should be reconsidered....
We conclude that the GADD45A gene is not involved in meningioma tumorigenesis. EPB41 gene expression was unchanged in all analyzed me …
Identification of a Two-Gene (PML-EPB41) Signature With Independent Prognostic Value in Osteosarcoma.
Liu S, Liu J, Yu X, Shen T, Fu Q. Liu S, et al. Front Oncol. 2020 Jan 24;9:1578. doi: 10.3389/fonc.2019.01578. eCollection 2019. Front Oncol. 2020. PMID: 32039036 Free PMC article.
Following by Cox proportional risk regression modeling, a 2-gene (PML-EPB41) signature was developed for prognostic prediction of patients with OSA. ...
Following by Cox proportional risk regression modeling, a 2-gene (PML-EPB41) signature was developed for prognostic prediction of pat …
Integrative Functional Genomics Implicates EPB41 Dysregulation in Hepatocellular Carcinoma Risk.
Yang X, Yu D, Ren Y, Wei J, Pan W, Zhou C, Zhou L, Liu Y, Yang M. Yang X, et al. Am J Hum Genet. 2016 Aug 4;99(2):275-86. doi: 10.1016/j.ajhg.2016.05.029. Epub 2016 Jul 21. Am J Hum Genet. 2016. PMID: 27453575 Free PMC article.
This polymorphism leads to HCC predisposition through modifying c-Myc-mediated transcriptional regulation of EPB41, with the risk rs157224T allele showing significantly decreased gene expression. Based on cell proliferation, wound healing, and transwell assays as well as t …
This polymorphism leads to HCC predisposition through modifying c-Myc-mediated transcriptional regulation of EPB41, with the risk rs1 …
87 results