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Items: 1 to 50 of 105

1.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.

Capalbo L, Bassi ZI, Geymonat M, Todesca S, Copoiu L, Enright AJ, Callaini G, Riparbelli MG, Yu L, Choudhary JS, Ferrero E, Wheatley S, Douglas ME, Mishima M, D'Avino PP.

Nat Commun. 2019 Oct 4;10(1):4513. doi: 10.1038/s41467-019-12507-9.

2.

Visualization and analysis of RNA-Seq assembly graphs.

Nazarie FW, Shih B, Angus T, Barnett MW, Chen SH, Summers KM, Klein K, Faulkner GJ, Saini HK, Watson M, Dongen SV, Enright AJ, Freeman TC.

Nucleic Acids Res. 2019 Aug 22;47(14):7262-7275. doi: 10.1093/nar/gkz599.

3.

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.

Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, Monahan JM, Vitsios DM, Vasiliauskaitė L, Comazzetto S, Rappsilber J, Allshire RC, Porse BT, Enright AJ, O'Carroll D.

Cell Res. 2019 Mar;29(3):221-232. doi: 10.1038/s41422-018-0128-1. Epub 2019 Jan 7.

4.

Non-coding RNA Expression, Function, and Variation during Drosophila Embryogenesis.

Schor IE, Bussotti G, Maleš M, Forneris M, Viales RR, Enright AJ, Furlong EEM.

Curr Biol. 2018 Nov 19;28(22):3547-3561.e9. doi: 10.1016/j.cub.2018.09.026. Epub 2018 Nov 1.

5.

Terminal uridylyltransferases target RNA viruses as part of the innate immune system.

Le Pen J, Jiang H, Di Domenico T, Kneuss E, Kosałka J, Leung C, Morgan M, Much C, Rudolph KLM, Enright AJ, O'Carroll D, Wang D, Miska EA.

Nat Struct Mol Biol. 2018 Sep;25(9):778-786. doi: 10.1038/s41594-018-0106-9. Epub 2018 Aug 13.

6.

Defective germline reprogramming rewires the spermatogonial transcriptome.

Vasiliauskaitė L, Berrens RV, Ivanova I, Carrieri C, Reik W, Enright AJ, O'Carroll D.

Nat Struct Mol Biol. 2018 May;25(5):394-404. doi: 10.1038/s41594-018-0058-0. Epub 2018 Apr 30.

7.

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci.

Amaral PP, Leonardi T, Han N, Viré E, Gascoigne DK, Arias-Carrasco R, Büscher M, Pandolfini L, Zhang A, Pluchino S, Maracaja-Coutinho V, Nakaya HI, Hemberg M, Shiekhattar R, Enright AJ, Kouzarides T.

Genome Biol. 2018 Mar 15;19(1):32. doi: 10.1186/s13059-018-1405-5.

8.

MicroRNA degradation by a conserved target RNA regulates animal behavior.

Bitetti A, Mallory AC, Golini E, Carrieri C, Carreño Gutiérrez H, Perlas E, Pérez-Rico YA, Tocchini-Valentini GP, Enright AJ, Norton WHJ, Mandillo S, O'Carroll D, Shkumatava A.

Nat Struct Mol Biol. 2018 Mar;25(3):244-251. doi: 10.1038/s41594-018-0032-x. Epub 2018 Feb 26.

9.

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.

Wu Q, Ferry QRV, Baeumler TA, Michaels YS, Vitsios DM, Habib O, Arnold R, Jiang X, Maio S, Steinkraus BR, Tapia M, Piazza P, Xu N, Holländer GA, Milne TA, Kim JS, Enright AJ, Bassett AR, Fulga TA.

Nat Commun. 2017 Dec 13;8(1):2109. doi: 10.1038/s41467-017-00686-2.

10.

A high-resolution mRNA expression time course of embryonic development in zebrafish.

White RJ, Collins JE, Sealy IM, Wali N, Dooley CM, Digby Z, Stemple DL, Murphy DN, Billis K, Hourlier T, Füllgrabe A, Davis MP, Enright AJ, Busch-Nentwich EM.

Elife. 2017 Nov 16;6. pii: e30860. doi: 10.7554/eLife.30860.

11.

Mirnovo: genome-free prediction of microRNAs from small RNA sequencing data and single-cells using decision forests.

Vitsios DM, Kentepozidou E, Quintais L, Benito-Gutiérrez E, van Dongen S, Davis MP, Enright AJ.

Nucleic Acids Res. 2017 Dec 1;45(21):e177. doi: 10.1093/nar/gkx836.

12.

The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence.

Ivanova I, Much C, Di Giacomo M, Azzi C, Morgan M, Moreira PN, Monahan J, Carrieri C, Enright AJ, O'Carroll D.

Mol Cell. 2017 Sep 21;67(6):1059-1067.e4. doi: 10.1016/j.molcel.2017.08.003. Epub 2017 Aug 31.

13.

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.

Morgan M, Much C, DiGiacomo M, Azzi C, Ivanova I, Vitsios DM, Pistolic J, Collier P, Moreira PN, Benes V, Enright AJ, O'Carroll D.

Nature. 2017 Aug 17;548(7667):347-351. doi: 10.1038/nature23318. Epub 2017 Aug 9.

14.

Extracellular vesicles are independent metabolic units with asparaginase activity.

Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C, Pluchino S.

Nat Chem Biol. 2017 Sep;13(9):951-955. doi: 10.1038/nchembio.2422. Epub 2017 Jul 3.

15.

MiR-277/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni.

Protasio AV, van Dongen S, Collins J, Quintais L, Ribeiro DM, Sessler F, Hunt M, Rinaldi G, Collins JJ, Enright AJ, Berriman M.

PLoS Negl Trop Dis. 2017 May 23;11(5):e0005559. doi: 10.1371/journal.pntd.0005559. eCollection 2017 May.

16.

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming.

Vasiliauskaitė L, Vitsios D, Berrens RV, Carrieri C, Reik W, Enright AJ, O'Carroll D.

Nat Struct Mol Biol. 2017 Jul;24(7):604-606. doi: 10.1038/nsmb.3413. Epub 2017 May 22.

17.

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.

Davis MP, Carrieri C, Saini HK, van Dongen S, Leonardi T, Bussotti G, Monahan JM, Auchynnikava T, Bitetti A, Rappsilber J, Allshire RC, Shkumatava A, O'Carroll D, Enright AJ.

EMBO Rep. 2017 Jul;18(7):1231-1247. doi: 10.15252/embr.201744059. Epub 2017 May 12.

18.

3' Uridylation controls mature microRNA turnover during CD4 T-cell activation.

Gutiérrez-Vázquez C, Enright AJ, Rodríguez-Galán A, Pérez-García A, Collier P, Jones MR, Benes V, Mizgerd JP, Mittelbrunn M, Ramiro AR, Sánchez-Madrid F.

RNA. 2017 Jun;23(6):882-891. doi: 10.1261/rna.060095.116. Epub 2017 Mar 28.

19.

Large-scale analysis of microRNA expression, epi-transcriptomic features and biogenesis.

Vitsios DM, Davis MP, van Dongen S, Enright AJ.

Nucleic Acids Res. 2017 Feb 17;45(3):1079-1090. doi: 10.1093/nar/gkw1031.

20.

spongeScan: A web for detecting microRNA binding elements in lncRNA sequences.

Furió-Tarí P, Tarazona S, Gabaldón T, Enright AJ, Conesa A.

Nucleic Acids Res. 2016 Jul 8;44(W1):W176-80. doi: 10.1093/nar/gkw443. Epub 2016 May 19.

21.

Improved definition of the mouse transcriptome via targeted RNA sequencing.

Bussotti G, Leonardi T, Clark MB, Mercer TR, Crawford J, Malquori L, Notredame C, Dinger ME, Mattick JS, Enright AJ.

Genome Res. 2016 May;26(5):705-16. doi: 10.1101/gr.199760.115.

22.

Exploring regulatory networks of miR-96 in the developing inner ear.

Lewis MA, Buniello A, Hilton JM, Zhu F, Zhang WI, Evans S, van Dongen S, Enright AJ, Steel KP.

Sci Rep. 2016 Mar 18;6:23363. doi: 10.1038/srep23363.

23.

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.

Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A, Ghazal P.

PLoS Biol. 2016 Mar 3;14(3):e1002364. doi: 10.1371/journal.pbio.1002364. eCollection 2016 Mar.

24.

Activation of the TGFβ pathway impairs endothelial to haematopoietic transition.

Vargel Ö, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, Shvartsman M, Enright AJ, Krijgsveld J, Lancrin C.

Sci Rep. 2016 Feb 19;6:21518. doi: 10.1038/srep21518.

25.

High-density P300 enhancers control cell state transitions.

Witte S, Bradley A, Enright AJ, Muljo SA.

BMC Genomics. 2015 Nov 6;16:903. doi: 10.1186/s12864-015-1905-6.

26.

Visualizing genome and systems biology: technologies, tools, implementation techniques and trends, past, present and future.

Pavlopoulos GA, Malliarakis D, Papanikolaou N, Theodosiou T, Enright AJ, Iliopoulos I.

Gigascience. 2015 Aug 25;4:38. doi: 10.1186/s13742-015-0077-2. eCollection 2015. Review.

27.

Chimira: analysis of small RNA sequencing data and microRNA modifications.

Vitsios DM, Enright AJ.

Bioinformatics. 2015 Oct 15;31(20):3365-7. doi: 10.1093/bioinformatics/btv380. Epub 2015 Jun 20.

28.

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing.

Clark MB, Mercer TR, Bussotti G, Leonardi T, Haynes KR, Crawford J, Brunck ME, Cao KA, Thomas GP, Chen WY, Taft RJ, Nielsen LK, Enright AJ, Mattick JS, Dinger ME.

Nat Methods. 2015 Apr;12(4):339-42. doi: 10.1038/nmeth.3321. Epub 2015 Mar 9.

PMID:
25751143
29.

Solid tumors of childhood display specific serum microRNA profiles.

Murray MJ, Raby KL, Saini HK, Bailey S, Wool SV, Tunnacliffe JM, Enright AJ, Nicholson JC, Coleman N.

Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):350-60. doi: 10.1158/1055-9965.EPI-14-0669. Epub 2014 Nov 21.

30.

Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells.

Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cervello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao C, Muller W, Garcia-Verdugo JM, Mathivanan S, Bachi A, Enright AJ, Mattick JS, Pluchino S.

Mol Cell. 2014 Oct 23;56(2):193-204. doi: 10.1016/j.molcel.2014.08.020. Epub 2014 Sep 18. Erratum in: Mol Cell. 2014 Nov 20;56(4):609.

31.

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia.

Camps C, Saini HK, Mole DR, Choudhry H, Reczko M, Guerra-Assunção JA, Tian YM, Buffa FM, Harris AL, Hatzigeorgiou AG, Enright AJ, Ragoussis J.

Mol Cancer. 2014 Feb 11;13:28. doi: 10.1186/1476-4598-13-28.

32.

Serum levels of mature microRNAs in DICER1-mutated pleuropulmonary blastoma.

Murray MJ, Bailey S, Raby KL, Saini HK, de Kock L, Burke GA, Foulkes WD, Enright AJ, Coleman N, Tischkowitz M.

Oncogenesis. 2014 Feb 10;3:e87. doi: 10.1038/oncsis.2014.1.

33.

Visualisation of BioPAX Networks using BioLayout Express (3D).

Wright DW, Angus T, Enright AJ, Freeman TC.

F1000Res. 2014 Oct 20;3:246. doi: 10.12688/f1000research.5499.1. eCollection 2014.

34.

Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state.

Hanning JE, Saini HK, Murray MJ, Caffarel MM, van Dongen S, Ward D, Barker EM, Scarpini CG, Groves IJ, Stanley MA, Enright AJ, Pett MR, Coleman N.

J Pathol. 2013 Nov;231(3):354-66. doi: 10.1002/path.4244.

PMID:
23913724
35.

Detecting and comparing non-coding RNAs in the high-throughput era.

Bussotti G, Notredame C, Enright AJ.

Int J Mol Sci. 2013 Jul 24;14(8):15423-58. doi: 10.3390/ijms140815423. Review.

36.

Kraken: a set of tools for quality control and analysis of high-throughput sequence data.

Davis MP, van Dongen S, Abreu-Goodger C, Bartonicek N, Enright AJ.

Methods. 2013 Sep 1;63(1):41-9. doi: 10.1016/j.ymeth.2013.06.027. Epub 2013 Jun 29.

37.

LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels.

Murray MJ, Saini HK, Siegler CA, Hanning JE, Barker EM, van Dongen S, Ward DM, Raby KL, Groves IJ, Scarpini CG, Pett MR, Thornton CM, Enright AJ, Nicholson JC, Coleman N; CCLG.

Cancer Res. 2013 Aug 1;73(15):4872-84. doi: 10.1158/0008-5472.CAN-12-2085. Epub 2013 Jun 17.

38.

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.

Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D.

Mol Cell. 2013 May 23;50(4):601-8. doi: 10.1016/j.molcel.2013.04.026.

39.

miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs.

Lupini L, Bassi C, Ferracin M, Bartonicek N, D'Abundo L, Zagatti B, Callegari E, Musa G, Moshiri F, Gramantieri L, Corrales FJ, Enright AJ, Sabbioni S, Negrini M.

Front Genet. 2013 Apr 25;4:64. doi: 10.3389/fgene.2013.00064. eCollection 2013.

40.

Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene.

Hanning JE, Saini HK, Murray MJ, van Dongen S, Davis MP, Barker EM, Ward DM, Scarpini CG, Enright AJ, Pett MR, Coleman N.

Br J Cancer. 2013 Feb 5;108(2):450-60. doi: 10.1038/bjc.2012.564. Epub 2013 Jan 8.

41.

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice.

Clare S, John V, Walker AW, Hill JL, Abreu-Goodger C, Hale C, Goulding D, Lawley TD, Mastroeni P, Frankel G, Enright AJ, Vigorito E, Dougan G.

Infect Immun. 2013 Mar;81(3):723-32. doi: 10.1128/IAI.00969-12. Epub 2012 Dec 21.

42.

A Neuronal Transcriptome Response Involving Stress Pathways is Buffered by Neuronal microRNAs.

Manakov SA, Morton A, Enright AJ, Grant SG.

Front Neurosci. 2012 Oct 30;6:156. doi: 10.3389/fnins.2012.00156. eCollection 2012.

43.

Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines.

Davis MP, Abreu-Goodger C, van Dongen S, Lu D, Tate PH, Bartonicek N, Kutter C, Liu P, Skarnes WC, Enright AJ, Dunham I.

PLoS One. 2012;7(8):e41762. doi: 10.1371/journal.pone.0041762. Epub 2012 Aug 17.

44.

MiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse fibroblast cells to iPSCs.

Lu D, Davis MP, Abreu-Goodger C, Wang W, Campos LS, Siede J, Vigorito E, Skarnes WC, Dunham I, Enright AJ, Liu P.

PLoS One. 2012;7(8):e40938. doi: 10.1371/journal.pone.0040938. Epub 2012 Aug 17.

45.

MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells.

Selcuklu SD, Donoghue MT, Rehmet K, de Souza Gomes M, Fort A, Kovvuru P, Muniyappa MK, Kerin MJ, Enright AJ, Spillane C.

J Biol Chem. 2012 Aug 24;287(35):29516-28. doi: 10.1074/jbc.M111.335943. Epub 2012 Jul 2.

46.

Large-scale analysis of microRNA evolution.

Guerra-Assunção JA, Enright AJ.

BMC Genomics. 2012 Jun 6;13:218. doi: 10.1186/1471-2164-13-218.

47.

Extent, causes, and consequences of small RNA expression variation in human adipose tissue.

Parts L, Hedman ÅK, Keildson S, Knights AJ, Abreu-Goodger C, van de Bunt M, Guerra-Assunção JA, Bartonicek N, van Dongen S, Mägi R, Nisbet J, Barrett A, Rantalainen M, Nica AC, Quail MA, Small KS, Glass D, Enright AJ, Winn J; MuTHER Consortium, Deloukas P, Dermitzakis ET, McCarthy MI, Spector TD, Durbin R, Lindgren CM.

PLoS Genet. 2012;8(5):e1002704. doi: 10.1371/journal.pgen.1002704. Epub 2012 May 10.

48.

Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction.

Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ Jr, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A.

Circulation. 2012 Jun 5;125(22):2751-61. doi: 10.1161/CIRCULATIONAHA.111.044354. Epub 2012 May 8.

49.

Evolutionary and functional insights into Leishmania META1: evidence for lateral gene transfer and a role for META1 in secretion.

Puri V, Goyal A, Sankaranarayanan R, Enright AJ, Vaidya T.

BMC Evol Biol. 2011 Nov 17;11:334. doi: 10.1186/1471-2148-11-334.

50.

Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data.

Hu M, Ayub Q, Guerra-Assunção JA, Long Q, Ning Z, Huang N, Romero IG, Mamanova L, Akan P, Liu X, Coffey AJ, Turner DJ, Swerdlow H, Burton J, Quail MA, Conrad DF, Enright AJ, Tyler-Smith C, Xue Y.

Hum Genet. 2012 May;131(5):665-74. doi: 10.1007/s00439-011-1111-9. Epub 2011 Nov 5.

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