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Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis.

Raouf J, Idborg H, Englund P, Alexanderson H, Dastmalchi M, Jakobsson PJ, Lundberg IE, Korotkova M.

Arthritis Res Ther. 2018 May 2;20(1):83. doi: 10.1186/s13075-018-1579-y.


Paediatric ventilation treatment of acute lung injury in Nordic intensive care units.

Jensen LL, Baratt-Due A, Englund PN, Harju JA, Sigurðsson TS, Liberg JP.

Acta Anaesthesiol Scand. 2015 May;59(5):568-75. doi: 10.1111/aas.12500. Epub 2015 Mar 12.


A passion for parasites.

Englund PT.

J Biol Chem. 2014 Dec 5;289(49):33712-29. doi: 10.1074/jbc.X114.620666. Epub 2014 Oct 21.


Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1.

Povelones ML, Tiengwe C, Gluenz E, Gull K, Englund PT, Jensen RE.

Mol Microbiol. 2013 Feb;87(4):713-29. doi: 10.1111/mmi.12089. Epub 2013 Jan 21.


Network news: the replication of kinetoplast DNA.

Jensen RE, Englund PT.

Annu Rev Microbiol. 2012;66:473-91. doi: 10.1146/annurev-micro-092611-150057. Review.


TbPIF8, a Trypanosoma brucei protein related to the yeast Pif1 helicase, is essential for cell viability and mitochondrial genome maintenance.

Wang J, Englund PT, Jensen RE.

Mol Microbiol. 2012 Feb;83(3):471-85. doi: 10.1111/j.1365-2958.2011.07938.x. Epub 2012 Jan 4.


Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.

Clayton AM, Guler JL, Povelones ML, Gluenz E, Gull K, Smith TK, Jensen RE, Englund PT.

Eukaryot Cell. 2011 Mar;10(3):286-92. doi: 10.1128/EC.00290-10. Epub 2011 Jan 14.


The killing of African trypanosomes by ethidium bromide.

Roy Chowdhury A, Bakshi R, Wang J, Yildirir G, Liu B, Pappas-Brown V, Tolun G, Griffith JD, Shapiro TA, Jensen RE, Englund PT.

PLoS Pathog. 2010 Dec 16;6(12):e1001226. doi: 10.1371/journal.ppat.1001226.


The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.

Gluenz E, Povelones ML, Englund PT, Gull K.

Mol Cell Biol. 2011 Mar;31(5):1012-21. doi: 10.1128/MCB.01176-10. Epub 2010 Dec 20.


TbPIF1, a Trypanosoma brucei mitochondrial DNA helicase, is essential for kinetoplast minicircle replication.

Liu B, Yildirir G, Wang J, Tolun G, Griffith JD, Englund PT.

J Biol Chem. 2010 Mar 5;285(10):7056-66. doi: 10.1074/jbc.M109.084038. Epub 2009 Dec 30.


TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.

Liu B, Wang J, Yildirir G, Englund PT.

PLoS Pathog. 2009 Sep;5(9):e1000589. doi: 10.1371/journal.ppat.1000589. Epub 2009 Sep 25.


Trypanosomes have six mitochondrial DNA helicases with one controlling kinetoplast maxicircle replication.

Liu B, Wang J, Yaffe N, Lindsay ME, Zhao Z, Zick A, Shlomai J, Englund PT.

Mol Cell. 2009 Aug 28;35(4):490-501. doi: 10.1016/j.molcel.2009.07.004. Epub 2009 Jul 30.


Sera from anti-Jo-1-positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells.

Barbasso Helmers S, Englund P, Engström M, Ahlin E, Fathi M, Janciauskiene S, Heimbürger M, Rönnelid J, Lundberg IE.

Arthritis Rheum. 2009 Aug;60(8):2524-30. doi: 10.1002/art.24683. Erratum in: Arthritis Rheum. 2009 Sep;60(9):2746.


Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.

Hu R, Mukhina GL, Lee SH, Jones RJ, Englund PT, Brown P, Sharkis SJ, Buckley JT, Brodsky RA.

Exp Hematol. 2009 Apr;37(4):423-434.e2. doi: 10.1016/j.exphem.2009.01.003.


A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.

Lindsay ME, Gluenz E, Gull K, Englund PT.

Mol Microbiol. 2008 Dec;70(6):1465-76. doi: 10.1111/j.1365-2958.2008.06493.x. Epub 2008 Oct 22.


What happens when Trypanosoma brucei leaves Africa.

Jensen RE, Simpson L, Englund PT.

Trends Parasitol. 2008 Oct;24(10):428-31. doi: 10.1016/ Epub 2008 Aug 18.


Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Protein Sci. 2001 May;Chapter 12:Unit 12.5. doi: 10.1002/0471140864.ps1205s02.


Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.

Li Z, Lindsay ME, Motyka SA, Englund PT, Wang CC.

PLoS Pathog. 2008 Apr 18;4(4):e1000048. doi: 10.1371/journal.ppat.1000048.


Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Mol Biol. 2001 May;Chapter 17:Unit17.8. doi: 10.1002/0471142727.mb1708s22.


The 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis in Trypanosoma brucei.

Autio KJ, Guler JL, Kastaniotis AJ, Englund PT, Hiltunen JK.

FEBS Lett. 2008 Mar 5;582(5):729-33. doi: 10.1016/j.febslet.2008.01.051. Epub 2008 Feb 5.


Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei.

Guler JL, Kriegova E, Smith TK, Lukes J, Englund PT.

Mol Microbiol. 2008 Mar;67(5):1125-42. doi: 10.1111/j.1365-2958.2008.06112.x. Epub 2008 Jan 23.


Effect of hydroxyurea on procyclic Trypanosoma brucei: an unconventional mechanism for achieving synchronous growth.

Chowdhury AR, Zhao Z, Englund PT.

Eukaryot Cell. 2008 Feb;7(2):425-8. Epub 2007 Dec 14.


p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation.

Zhao Z, Lindsay ME, Roy Chowdhury A, Robinson DR, Englund PT.

EMBO J. 2008 Jan 9;27(1):143-54. Epub 2007 Dec 6.


Mitochondrial origin-binding protein UMSBP mediates DNA replication and segregation in trypanosomes.

Milman N, Motyka SA, Englund PT, Robinson D, Shlomai J.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19250-5. Epub 2007 Nov 28.


The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis.

Lohmander LS, Englund PM, Dahl LL, Roos EM.

Am J Sports Med. 2007 Oct;35(10):1756-69. Epub 2007 Aug 29. Review.


The rotational dynamics of kinetoplast DNA replication.

Liu Y, Englund PT.

Mol Microbiol. 2007 May;64(3):676-90.


A fatty-acid synthesis mechanism specialized for parasitism.

Lee SH, Stephens JL, Englund PT.

Nat Rev Microbiol. 2007 Apr;5(4):287-97. Review.


Restricted T cell receptor BV gene usage in the lungs and muscles of patients with idiopathic inflammatory myopathies.

Englund P, Wahlström J, Fathi M, Rasmussen E, Grunewald J, Tornling G, Lundberg IE.

Arthritis Rheum. 2007 Jan;56(1):372-83.


Mitochondrial fatty acid synthesis in Trypanosoma brucei.

Stephens JL, Lee SH, Paul KS, Englund PT.

J Biol Chem. 2007 Feb 16;282(7):4427-36. Epub 2006 Dec 12.


Fatty acid synthesis by elongases in trypanosomes.

Lee SH, Stephens JL, Paul KS, Englund PT.

Cell. 2006 Aug 25;126(4):691-9.


Signs of inflammation in both symptomatic and asymptomatic muscles from patients with polymyositis and dermatomyositis.

Dorph C, Englund P, Nennesmo I, Lundberg IE.

Ann Rheum Dis. 2006 Dec;65(12):1565-71. Epub 2006 Jul 10.


Role of p38 in replication of Trypanosoma brucei kinetoplast DNA.

Liu B, Molina H, Kalume D, Pandey A, Griffith JD, Englund PT.

Mol Cell Biol. 2006 Jul;26(14):5382-93.


Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei.

Motyka SA, Drew ME, Yildirir G, Englund PT.

J Biol Chem. 2006 Jul 7;281(27):18499-506. Epub 2006 May 10.


RNAi libraries and kinetoplast DNA.

Englund PT, Agbo EE, Lindsay ME, Liu B, Liu Y, Motyka SA, Yildirir G, Zhao Z.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1409-12.


Effects of RNA interference of Trypanosoma brucei structure-specific endonuclease-I on kinetoplast DNA replication.

Liu Y, Motyka SA, Englund PT.

J Biol Chem. 2005 Oct 21;280(42):35513-20. Epub 2005 Aug 11.


The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.

El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran AN, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, Caler E, Cerqueira GC, Branche C, Haas B, Anupama A, Arner E, Aslund L, Attipoe P, Bontempi E, Bringaud F, Burton P, Cadag E, Campbell DA, Carrington M, Crabtree J, Darban H, da Silveira JF, de Jong P, Edwards K, Englund PT, Fazelina G, Feldblyum T, Ferella M, Frasch AC, Gull K, Horn D, Hou L, Huang Y, Kindlund E, Klingbeil M, Kluge S, Koo H, Lacerda D, Levin MJ, Lorenzi H, Louie T, Machado CR, McCulloch R, McKenna A, Mizuno Y, Mottram JC, Nelson S, Ochaya S, Osoegawa K, Pai G, Parsons M, Pentony M, Pettersson U, Pop M, Ramirez JL, Rinta J, Robertson L, Salzberg SL, Sanchez DO, Seyler A, Sharma R, Shetty J, Simpson AJ, Sisk E, Tammi MT, Tarleton R, Teixeira S, Van Aken S, Vogt C, Ward PN, Wickstead B, Wortman J, White O, Fraser CM, Stuart KD, Andersson B.

Science. 2005 Jul 15;309(5733):409-15.


Fellowship of the rings: the replication of kinetoplast DNA.

Liu B, Liu Y, Motyka SA, Agbo EE, Englund PT.

Trends Parasitol. 2005 Aug;21(8):363-9. Review.


Multiple triclosan targets in Trypanosoma brucei.

Paul KS, Bacchi CJ, Englund PT.

Eukaryot Cell. 2004 Aug;3(4):855-61.


RNA interference for analysis of gene function in trypanosomatids.

Motyka SA, Englund PT.

Curr Opin Microbiol. 2004 Aug;7(4):362-8. Review.


Purification and identification of a fatty acyl-CoA synthetase from Trypanosoma brucei.

Jiang DW, Werbovetz KA, Varadhachary A, Cole RN, Englund PT.

Mol Biochem Parasitol. 2004 May;135(1):149-52. No abstract available.


Defects in the N-linked oligosaccharide biosynthetic pathway in a Trypanosoma brucei glycosylation mutant.

Acosta-Serrano A, O'Rear J, Quellhorst G, Lee SH, Hwa KY, Krag SS, Englund PT.

Eukaryot Cell. 2004 Apr;3(2):255-63.


Closing the gaps in kinetoplast DNA network replication.

Klingbeil MM, Englund PT.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4333-4. Epub 2004 Mar 22. Review. No abstract available.


Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome.

Motyka SA, Zhao Z, Gull K, Englund PT.

Mol Biochem Parasitol. 2004 Mar;134(1):163-7. No abstract available.


Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans.

Liniger M, Acosta-Serrano A, Van Den Abbeele J, Kunz Renggli C, Brun R, Englund PT, Roditi I.

Int J Parasitol. 2003 Oct;33(12):1319-28.


The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library.

Drew ME, Morris JC, Wang Z, Wells L, Sanchez M, Landfear SM, Englund PT.

J Biol Chem. 2003 Nov 21;278(47):46596-600. Epub 2003 Sep 12.


Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes.

Saxowsky TT, Choudhary G, Klingbeil MM, Englund PT.

J Biol Chem. 2003 Dec 5;278(49):49095-101. Epub 2003 Sep 8.


Isolation of kinetoplast DNA.

Shapiro TA, Klein VA, Englund PT.

Methods Mol Biol. 1999;94:61-7. No abstract available.


CBA/J mice infected with Trypanosoma cruzi: an experimental model for inflammatory myopathies.

Andersson J, Englund P, Sunnemark D, Dahlstedt A, Westerblad H, Nennesmo I, Orn A, Lundberg IE.

Muscle Nerve. 2003 Apr;27(4):442-8.


Kinetoplast DNA network: evolution of an improbable structure.

Lukes J, Guilbride DL, Votýpka J, Zíková A, Benne R, Englund PT.

Eukaryot Cell. 2002 Aug;1(4):495-502. Review. No abstract available.

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