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Items: 1 to 50 of 108

1.

Ion-Ion Proton Transfer and Parallel Ion Parking for the Analysis of Mixtures of Intact Proteins on a Modified Orbitrap Mass Analyzer.

Ugrin SA, English AM, Syka JEP, Bai DL, Anderson LC, Shabanowitz J, Hunt DF.

J Am Soc Mass Spectrom. 2019 Oct;30(10):2163-2173. doi: 10.1007/s13361-019-02290-8. Epub 2019 Aug 7.

2.

Knowing When to Let Go: Lysosomes Regulate Inter-Mitochondrial Tethering.

English AM, Hughes AL.

Dev Cell. 2019 Aug 5;50(3):259-260. doi: 10.1016/j.devcel.2019.07.019.

PMID:
31386859
3.

Ctt1 catalase activity potentiates antifungal azoles in the emerging opportunistic pathogen Saccharomyces cerevisiae.

Martins D, Nguyen D, English AM.

Sci Rep. 2019 Jun 24;9(1):9185. doi: 10.1038/s41598-019-45070-w.

4.
5.

Effect of Early Calf-Hood Nutrition on the Transcriptional Regulation of the Hypothalamic-Pituitary-Testicular axis in Holstein-Friesian Bull Calves.

English AM, Byrne CJ, Cormican P, Waters SM, Fair S, Kenny DA.

Sci Rep. 2018 Nov 8;8(1):16577. doi: 10.1038/s41598-018-34611-4.

6.

Role of early life nutrition on regulating the hypothalamic–anterior pituitary–testicular axis of the bull

English AM, Kenny DA, Byrne CJ, Sauerwein H, Urh C, Crowe MA, Staub C, Waters SM, Fair S.

Reproduction. 2018 Oct 1;156(4):283–297. doi: 10.1530/REP-17-0671.

PMID:
30305241
7.

Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa.

Martins D, McKay G, Sampathkumar G, Khakimova M, English AM, Nguyen D.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9797-9802. doi: 10.1073/pnas.1804525115. Epub 2018 Sep 10.

8.

Predicting structural and energetic changes in Met-aromatic motifs on methionine oxidation to the sulfoxide and sulfone.

Orabi EA, English AM.

Phys Chem Chem Phys. 2018 Sep 12;20(35):23132-23141. doi: 10.1039/c8cp03277g.

PMID:
30168822
9.

LC-MS/MS Proteoform Profiling Exposes Cytochrome c Peroxidase Self-Oxidation in Mitochondria and Functionally Important Hole Hopping from Its Heme.

Kathiresan M, English AM.

J Am Chem Soc. 2018 Sep 26;140(38):12033-12039. doi: 10.1021/jacs.8b05966. Epub 2018 Sep 12.

PMID:
30145880
10.

Effect of early calf-hood nutrition on the transcriptomic profile of subcutaneous adipose tissue in Holstein-Friesian bulls.

English AM, Waters SM, Cormican P, Byrne CJ, Fair S, Kenny DA.

BMC Genomics. 2018 Apr 24;19(1):281. doi: 10.1186/s12864-018-4681-2.

11.

A Simple Additive Potential Model for Simulating Hydrogen Peroxide in Chemical and Biological Systems.

Orabi EA, English AM.

J Chem Theory Comput. 2018 May 8;14(5):2808-2821. doi: 10.1021/acs.jctc.8b00246. Epub 2018 Apr 23.

PMID:
29630362
12.

Modeling Protein S-Aromatic Motifs Reveals Their Structural and Redox Flexibility.

Orabi EA, English AM.

J Phys Chem B. 2018 Apr 12;122(14):3760-3770. doi: 10.1021/acs.jpcb.8b00089. Epub 2018 Mar 28.

PMID:
29533644
13.

Plane of nutrition before and after 6 months of age in Holstein-Friesian bulls: I. Effects on performance, body composition, age at puberty, and postpubertal semen production.

Byrne CJ, Fair S, English AM, Cirot M, Staub C, Lonergan P, Kenny DA.

J Dairy Sci. 2018 Apr;101(4):3447-3459. doi: 10.3168/jds.2017-13719. Epub 2018 Feb 7.

14.

Plane of nutrition before and after 6 months of age in Holstein-Friesian bulls: II. Effects on metabolic and reproductive endocrinology and identification of physiological markers of puberty and sexual maturation.

Byrne CJ, Fair S, English AM, Urh C, Sauerwein H, Crowe MA, Lonergan P, Kenny DA.

J Dairy Sci. 2018 Apr;101(4):3460-3475. doi: 10.3168/jds.2017-13720. Epub 2018 Feb 4.

15.

Genomic identification, expression profiling, and functional characterization of CatSper channels in the bovine.

Johnson GP, English AM, Cronin S, Hoey DA, Meade KG, Fair S.

Biol Reprod. 2017 Aug 1;97(2):302-312. doi: 10.1093/biolre/iox082.

PMID:
29044427
16.

Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis.

Weisbrod CR, Kaiser NK, Syka JEP, Early L, Mullen C, Dunyach JJ, English AM, Anderson LC, Blakney GT, Shabanowitz J, Hendrickson CL, Marshall AG, Hunt DF.

J Am Soc Mass Spectrom. 2017 Sep;28(9):1787-1795. doi: 10.1007/s13361-017-1702-3. Epub 2017 Jul 18.

17.

Effect of breed, plane of nutrition and age on growth, scrotal development, metabolite concentrations and on systemic gonadotropin and testosterone concentrations following a GnRH challenge in young dairy bulls.

Byrne CJ, Fair S, English AM, Urh C, Sauerwein H, Crowe MA, Lonergan P, Kenny DA.

Theriogenology. 2017 Jul 1;96:58-68. doi: 10.1016/j.theriogenology.2017.04.002. Epub 2017 Apr 3.

PMID:
28532840
18.

LC-MS/MS suggests that hole hopping in cytochrome c peroxidase protects its heme from oxidative modification by excess H2O2.

Kathiresan M, English AM.

Chem Sci. 2017 Feb 1;8(2):1152-1162. doi: 10.1039/c6sc03125k. Epub 2016 Sep 7.

19.

Do Mammalian Cells Really Need to Export and Import Heme?

Ponka P, Sheftel AD, English AM, Scott Bohle D, Garcia-Santos D.

Trends Biochem Sci. 2017 May;42(5):395-406. doi: 10.1016/j.tibs.2017.01.006. Epub 2017 Feb 20. Review.

PMID:
28254242
20.

Effect of milk replacer and concentrate intake on growth rate, feeding behaviour and systemic metabolite concentrations of pre-weaned bull calves of two dairy breeds.

Byrne CJ, Fair S, English AM, Johnston D, Lonergan P, Kenny DA.

Animal. 2017 Sep;11(9):1531-1538. doi: 10.1017/S1751731117000350. Epub 2017 Feb 20.

PMID:
28215216
21.

Dietary polyunsaturated fatty acid supplementation of young post-pubertal dairy bulls alters the fatty acid composition of seminal plasma and spermatozoa but has no effect on semen volume or sperm quality.

Byrne CJ, Fair S, English AM, Holden SA, Dick JR, Lonergan P, Kenny DA.

Theriogenology. 2017 Mar 1;90:289-300. doi: 10.1016/j.theriogenology.2016.12.014. Epub 2016 Dec 18.

PMID:
28166982
22.

Targeted proteomics identify metabolism-dependent interactors of yeast cytochrome c peroxidase: implications in stress response and heme trafficking.

Kathiresan M, English AM.

Metallomics. 2016 Apr;8(4):434-43. doi: 10.1039/c5mt00330j. Epub 2016 Mar 16.

PMID:
26980054
23.

Benchmarking Rapid TLES Simulations of Gas Diffusion in Proteins: Mapping O2 Migration and Escape in Myoglobin as a Case Study.

Shadrina MS, English AM, Peslherbe GH.

J Chem Theory Comput. 2016 Apr 12;12(4):2038-46. doi: 10.1021/acs.jctc.5b01132. Epub 2016 Mar 14.

PMID:
26938707
24.

Analyses of Histone Proteoforms Using Front-end Electron Transfer Dissociation-enabled Orbitrap Instruments.

Anderson LC, Karch KR, Ugrin SA, Coradin M, English AM, Sidoli S, Shabanowitz J, Garcia BA, Hunt DF.

Mol Cell Proteomics. 2016 Mar;15(3):975-88. doi: 10.1074/mcp.O115.053843. Epub 2016 Jan 19.

25.

Analysis of Monoclonal Antibody Sequence and Post-translational Modifications by Time-controlled Proteolysis and Tandem Mass Spectrometry.

Zhang L, English AM, Bai DL, Ugrin SA, Shabanowitz J, Ross MM, Hunt DF, Wang WH.

Mol Cell Proteomics. 2016 Apr;15(4):1479-88. doi: 10.1074/mcp.O115.056721. Epub 2015 Nov 29.

26.

O2 and Water Migration Pathways between the Solvent and Heme Pockets of Hemoglobin with Open and Closed Conformations of the Distal HisE7.

Shadrina MS, Peslherbe GH, English AM.

Biochemistry. 2015 Sep 1;54(34):5279-89. doi: 10.1021/acs.biochem.5b00369. Epub 2015 Aug 19.

PMID:
26226401
27.

Quaternary-Linked Changes in Structure and Dynamics That Modulate O2 Migration within Hemoglobin's Gas Diffusion Tunnels.

Shadrina MS, Peslherbe GH, English AM.

Biochemistry. 2015 Sep 1;54(34):5268-78. doi: 10.1021/acs.biochem.5b00368. Epub 2015 Aug 19.

PMID:
26226318
28.

Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity.

Metushi IG, Wriston A, Banerjee P, Gohlke BO, English AM, Lucas A, Moore C, Sidney J, Buus S, Ostrov DA, Mallal S, Phillips E, Shabanowitz J, Hunt DF, Preissner R, Peters B.

PLoS One. 2015 May 29;10(5):e0124878. doi: 10.1371/journal.pone.0124878. eCollection 2015.

29.

Peroxynitrite and hydrogen peroxide elicit similar cellular stress responses mediated by the Ccp1 sensor protein.

Martins D, Bakas I, McIntosh K, English AM.

Free Radic Biol Med. 2015 Aug;85:138-47. doi: 10.1016/j.freeradbiomed.2015.04.010. Epub 2015 Apr 14.

PMID:
25881547
30.

Protein derivatization and sequential ion/ion reactions to enhance sequence coverage produced by electron transfer dissociation mass spectrometry.

Anderson LC, English AM, Wang W, Bai DL, Shabanowitz J, Hunt DF.

Int J Mass Spectrom. 2015 Feb 1;377:617-624.

31.

Respiration triggers heme transfer from cytochrome c peroxidase to catalase in yeast mitochondria.

Kathiresan M, Martins D, English AM.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17468-73. doi: 10.1073/pnas.1409692111. Epub 2014 Nov 24.

32.

SOD1 oxidation and formation of soluble aggregates in yeast: relevance to sporadic ALS development.

Martins D, English AM.

Redox Biol. 2014 Mar 26;2:632-9. doi: 10.1016/j.redox.2014.03.005. eCollection 2014.

33.

Cholesterol-loaded-cyclodextrins improve the post-thaw quality of stallion sperm.

Murphy C, English AM, Holden SA, Fair S.

Anim Reprod Sci. 2014 Mar;145(3-4):123-9. doi: 10.1016/j.anireprosci.2014.01.013. Epub 2014 Feb 6.

PMID:
24583046
34.

Catalase activity is stimulated by H(2)O(2) in rich culture medium and is required for H(2)O(2) resistance and adaptation in yeast.

Martins D, English AM.

Redox Biol. 2014 Jan 10;2:308-13. doi: 10.1016/j.redox.2013.12.019. eCollection 2014.

35.

Cells with impaired mitochondrial H2O2 sensing generate less •OH radicals and live longer.

Martins D, Titorenko VI, English AM.

Antioxid Redox Signal. 2014 Oct 1;21(10):1490-503. doi: 10.1089/ars.2013.5575. Epub 2014 Feb 19.

PMID:
24382195
36.

Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity.

Chen S, Li Y, Depontieu FR, McMiller TL, English AM, Shabanowitz J, Kos F, Sidney J, Sette A, Rosenberg SA, Hunt DF, Mariuzza RA, Topalian SL.

J Immunol. 2013 Nov 15;191(10):5097-106. doi: 10.4049/jimmunol.1300467. Epub 2013 Oct 9.

37.

Catalysis of nitrite generation from nitroglycerin by glyceraldehyde-3-phosphate dehydrogenase (GAPDH).

Seabra AB, Ouellet M, Antonic M, Chrétien MN, English AM.

Nitric Oxide. 2013 Nov 30;35:116-22. doi: 10.1016/j.niox.2013.09.003. Epub 2013 Sep 21.

PMID:
24064205
38.

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, Freeman SD, Shabanowitz J, Pratt G, Craddock C, Williams ME, Hunt DF, Engelhard VH.

Sci Transl Med. 2013 Sep 18;5(203):203ra125. doi: 10.1126/scitranslmed.3006061.

39.

Front-end electron transfer dissociation: a new ionization source.

Earley L, Anderson LC, Bai DL, Mullen C, Syka JE, English AM, Dunyach JJ, Stafford GC Jr, Shabanowitz J, Hunt DF, Compton PD.

Anal Chem. 2013 Sep 3;85(17):8385-90. doi: 10.1021/ac401783f. Epub 2013 Aug 19.

40.

Cytochrome c peroxidase is a mitochondrial heme-based H2O2 sensor that modulates antioxidant defense.

Martins D, Kathiresan M, English AM.

Free Radic Biol Med. 2013 Dec;65:541-551. doi: 10.1016/j.freeradbiomed.2013.06.037. Epub 2013 Jul 2.

PMID:
23831190
41.

Rapid high-yield N-acylation of aminothiols: N-acetylglutathione and N-acetylhomocysteine and their thiol pK(a) values.

Shen B, Bazin C, English AM.

J Pept Sci. 2013 May;19(5):263-7. doi: 10.1002/psc.2492. Epub 2013 Mar 27.

PMID:
23532793
42.

The stringent response controls catalases in Pseudomonas aeruginosa and is required for hydrogen peroxide and antibiotic tolerance.

Khakimova M, Ahlgren HG, Harrison JJ, English AM, Nguyen D.

J Bacteriol. 2013 May;195(9):2011-20. doi: 10.1128/JB.02061-12. Epub 2013 Mar 1.

43.

Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles.

Mothé BR, Southwood S, Sidney J, English AM, Wriston A, Hoof I, Shabanowitz J, Hunt DF, Sette A.

Immunogenetics. 2013 May;65(5):371-86. doi: 10.1007/s00251-013-0686-9. Epub 2013 Feb 17.

44.

Overcoming matrix effects in the chemiluminescence determination of extracellular adenosine triphosphate in erythrocyte suspensions.

Clarke A, Ouellet M, English AM.

Anal Biochem. 2013 May 15;436(2):66-8. doi: 10.1016/j.ab.2013.01.024. Epub 2013 Jan 31.

PMID:
23376575
45.

Effective simulations of gas diffusion through kinetically accessible tunnels in multisubunit proteins: O2 pathways and escape routes in T-state deoxyhemoglobin.

Shadrina MS, English AM, Peslherbe GH.

J Am Chem Soc. 2012 Jul 11;134(27):11177-84. doi: 10.1021/ja300903c. Epub 2012 Jun 26.

PMID:
22690872
46.

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.

Ostrov DA, Grant BJ, Pompeu YA, Sidney J, Harndahl M, Southwood S, Oseroff C, Lu S, Jakoncic J, de Oliveira CA, Yang L, Mei H, Shi L, Shabanowitz J, English AM, Wriston A, Lucas A, Phillips E, Mallal S, Grey HM, Sette A, Hunt DF, Buus S, Peters B.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9959-64. doi: 10.1073/pnas.1207934109. Epub 2012 May 29.

47.

Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301).

Moore C, Sidney J, English AM, Wriston A, Hunt DF, Shabanowitz J, Southwood S, Bradley K, Lafont BA, Mothé BR, Sette A.

Immunogenetics. 2012 Jun;64(6):461-8. doi: 10.1007/s00251-012-0600-x. Epub 2012 Jan 26.

48.

ESI-MS quantitation of iron as its 4-(2-pyridylazo)resorcinol (PAR) complex: application to pharmaceutical tablets containing iron oxide pigment.

Susanto D, English AM, Sharma R, Kwong E.

J Mass Spectrom. 2011 May;46(5):508-16. doi: 10.1002/jms.1919.

PMID:
21520348
49.

Kinetics and mechanism of S-nitrosothiol acid-catalyzed hydrolysis: sulfur activation promotes facile NO+ release.

Moran EE, Timerghazin QK, Kwong E, English AM.

J Phys Chem B. 2011 Mar 31;115(12):3112-26. doi: 10.1021/jp1035597. Epub 2011 Mar 8.

PMID:
21384833
50.

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

Goldberg AA, Richard VR, Kyryakov P, Bourque SD, Beach A, Burstein MT, Glebov A, Koupaki O, Boukh-Viner T, Gregg C, Juneau M, English AM, Thomas DY, Titorenko VI.

Aging (Albany NY). 2010 Jul;2(7):393-414.

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