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Items: 40


Update in Critical Care 2019.

Arabi Y, Mallampalli R, Englert JA, Bosch NA, Walkey AJ, Al-Dorzi HM.

Am J Respir Crit Care Med. 2020 Mar 16. doi: 10.1164/rccm.202002-0285UP. [Epub ahead of print] No abstract available.


Depletion of microRNA-451 in response to allergen exposure accentuates asthmatic inflammation by regulating Sirtuin2.

Chung S, Lee YG, Karpurapu M, Englert JA, Ballinger MN, Davis IC, Park GY, Christman JW.

Am J Physiol Lung Cell Mol Physiol. 2020 Mar 11. doi: 10.1152/ajplung.00457.2019. [Epub ahead of print]


Semi-quantitative visual assessment of chest radiography is associated with clinical outcomes in critically ill patients.

Mason SE, Dieffenbach PB, Englert JA, Rogers AA, Massaro AF, Fredenburgh LE, Higuera A, Pinilla-Vera M, Vilas M, San Jose Estepar R, Washko GR, Baron RM, Ash SY.

Respir Res. 2019 Oct 12;20(1):218. doi: 10.1186/s12931-019-1201-0.


Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome.

Englert JA, Bobba C, Baron RM.

JCI Insight. 2019 Jan 24;4(2). pii: 124061. doi: 10.1172/jci.insight.124061. [Epub ahead of print] Review.


Sirtuin 2 enhances allergic asthmatic inflammation.

Lee YG, Reader BF, Herman D, Streicher A, Englert JA, Ziegler M, Chung S, Karpurapu M, Park GY, Christman JW, Ballinger MN.

JCI Insight. 2019 Feb 21;4(4). pii: 124710. doi: 10.1172/jci.insight.124710. eCollection 2019 Feb 21.


Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation.

Englert JA, Cho MH, Lamb AE, Shumyatcher M, Barragan-Bradford D, Basil MC, Higuera A, Isabelle C, Vera MP, Dieffenbach PB, Fredenburgh LE, Kang JB, Bhatt AS, Antin JH, Ho VT, Soiffer RJ, Howrylak JA, Himes BE, Baron RM.

Respir Res. 2019 Jan 21;20(1):15. doi: 10.1186/s12931-019-0981-6.


A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.

Fredenburgh LE, Perrella MA, Barragan-Bradford D, Hess DR, Peters E, Welty-Wolf KE, Kraft BD, Harris RS, Maurer R, Nakahira K, Oromendia C, Davies JD, Higuera A, Schiffer KT, Englert JA, Dieffenbach PB, Berlin DA, Lagambina S, Bouthot M, Sullivan AI, Nuccio PF, Kone MT, Malik MJ, Porras MAP, Finkelsztein E, Winkler T, Hurwitz S, Serhan CN, Piantadosi CA, Baron RM, Thompson BT, Choi AM.

JCI Insight. 2018 Dec 6;3(23). pii: 124039. doi: 10.1172/jci.insight.124039.


FoxO1 is a critical regulator of M2-like macrophage activation in allergic asthma.

Chung S, Kim JY, Song MA, Park GY, Lee YG, Karpurapu M, Englert JA, Ballinger MN, Pabla N, Chung HY, Christman JW.

Allergy. 2019 Mar;74(3):535-548. doi: 10.1111/all.13626. Epub 2018 Nov 5.


Tetralogy of Fallot: Case-Based Update for the Treatment of Adult Congenital Patients.

Englert JAR 3rd, Gupta T, Joury AU, Shah SB.

Curr Probl Cardiol. 2019 Feb;44(2):46-81. doi: 10.1016/j.cpcardiol.2018.03.002. Epub 2018 Mar 22. Review. No abstract available.


Unhinging the machinery of sepsis: An unexpected role for vascular smooth muscle.

Englert JA, Christman JW, Ballinger MN.

J Leukoc Biol. 2018 Oct;104(4):661-663. doi: 10.1002/JLB.CE0618-236R. Epub 2018 Aug 22. No abstract available.


Trends in "usual care" for septic shock.

Hume PS, Varon J, Englert JA, Hurwitz S, Klompas M, Baron RM, Rhee C.

Infect Control Hosp Epidemiol. 2018 Sep;39(9):1125-1126. doi: 10.1017/ice.2018.154. Epub 2018 Jul 19. No abstract available.


Bilateral Lung Masses and Dyspnea in a Young Woman.

Hay BR, Shilo K, Englert JA.

Ann Am Thorac Soc. 2018 Jul;15(7):875-879. doi: 10.1513/AnnalsATS.201801-066CC. No abstract available.


An Unexpected Expectoration.

Casey JD, Englert JA, Katz JT, Miller AL, Loscalzo J.

N Engl J Med. 2018 Mar 1;378(9):853-858. doi: 10.1056/NEJMcps1711048. No abstract available.


Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma.

Higuita-Castro N, Nelson MT, Shukla V, Agudelo-Garcia PA, Zhang W, Duarte-Sanmiguel SM, Englert JA, Lannutti JJ, Hansford DJ, Ghadiali SN.

Sci Rep. 2017 Sep 14;7(1):11623. doi: 10.1038/s41598-017-12044-9.


Zinc deficiency primes the lung for ventilator-induced injury.

Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry, Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM.

JCI Insight. 2017 Jun 2;2(11). pii: 86507. doi: 10.1172/jci.insight.86507. eCollection 2017 Jun 2.


Steroids and β-Agonists in Acute Respiratory Distress Syndrome: Timing Is Everything.

Englert JA, Crouser ED.

Crit Care Med. 2017 May;45(5):914-915. doi: 10.1097/CCM.0000000000002385. No abstract available.


Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney.

Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F654-F660. doi: 10.1152/ajprenal.00523.2016. Epub 2016 Nov 9.


Interstitial Lung Abnormalities Are Associated with Acute Respiratory Distress Syndrome.

Putman RK, Hunninghake GM, Dieffenbach PB, Barragan-Bradford D, Serhan K, Adams U, Hatabu H, Nishino M, Padera RF, Fredenburgh LE, Baron RM, Englert JA.

Am J Respir Crit Care Med. 2017 Jan 1;195(1):138-141. doi: 10.1164/rccm.201604-0818LE. No abstract available.


Mechanical Circulatory Support for the Failing Heart: Continuous-Flow Left Ventricular Assist Devices.

Englert JA 3rd, Davis JA, Krim SR.

Ochsner J. 2016 Fall;16(3):263-9. Review.


Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.

Ghanta S, Tsoyi K, Liu X, Nakahira K, Ith B, Coronata AA, Fredenburgh LE, Englert JA, Piantadosi CA, Choi AM, Perrella MA.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):300-309. doi: 10.1165/rcmb.2016-0061OC.


Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis.

Englert JA, Rogers AJ.

Clin Chest Med. 2016 Jun;37(2):321-31. doi: 10.1016/j.ccm.2016.01.011. Epub 2016 Mar 12. Review.


Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy.

Hou HW, Wu L, Amador-Munoz DP, Vera MP, Coronata A, Englert JA, Levy BD, Baron RM, Han J.

Lab Chip. 2016 Feb 21;16(4):688-99. doi: 10.1039/c5lc01110h. Epub 2016 Jan 15.


Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity.

Englert JA, Macias AA, Amador-Munoz D, Pinilla Vera M, Isabelle C, Guan J, Magaoay B, Suarez Velandia M, Coronata A, Lee A, Fredenburgh LE, Culley DJ, Crosby G, Baron RM.

Anesthesiology. 2015 Aug;123(2):377-88. doi: 10.1097/ALN.0000000000000742.


Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion.

Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM.

Am J Respir Cell Mol Biol. 2012 Aug;47(2):209-17. doi: 10.1165/rcmb.2011-0447OC. Epub 2012 Apr 19.


Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA.

J Immunol. 2011 Nov 15;187(10):5255-67. doi: 10.4049/jimmunol.1101186. Epub 2011 Oct 3.


Characterization of macroautophagic flux in vivo using a leupeptin-based assay.

Haspel J, Shaik RS, Ifedigbo E, Nakahira K, Dolinay T, Englert JA, Choi AM.

Autophagy. 2011 Jun;7(6):629-42. Epub 2011 Jun 1.


Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.

Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM.

Nat Immunol. 2011 Mar;12(3):222-30. doi: 10.1038/ni.1980. Epub 2010 Dec 12.


Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock.

Yang R, Harada T, Mollen KP, Prince JM, Levy RM, Englert JA, Gallowitsch-Puerta M, Yang L, Yang H, Tracey KJ, Harbrecht BG, Billiar TR, Fink MP.

Mol Med. 2006 Apr-Jun;12(4-6):105-14.


The phase 2 enzyme inducers ethacrynic acid, DL-sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 cells.

Killeen ME, Englert JA, Stolz DB, Song M, Han Y, Delude RL, Kellum JA, Fink MP.

J Pharmacol Exp Ther. 2006 Mar;316(3):1070-9. Epub 2005 Dec 28.


The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.

Sappington PL, Cruz RJ Jr, Harada T, Yang R, Han Y, Englert JA, Ajami AA, Killeen ME, Delude RL, Fink MP.

Biochem Pharmacol. 2005 Nov 25;70(11):1579-92. Epub 2005 Oct 13.


The multiple organ dysfunction syndrome and late-phase mortality in sepsis.

Englert JA, Fink MP.

Curr Infect Dis Rep. 2005 Sep;7(5):335-41.


Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2 dependent mechanism.

Yang R, Harada T, Li J, Uchiyama T, Han Y, Englert JA, Fink MP.

Intensive Care Med. 2005 May;31(5):709-17. Epub 2005 Mar 22.


Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway.

Han Y, Englert JA, Delude RL, Fink MP.

Shock. 2005 Jan;23(1):45-53.


Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.

Han Y, Englert JA, Yang R, Delude RL, Fink MP.

J Pharmacol Exp Ther. 2005 Mar;312(3):1097-105. Epub 2004 Nov 3.


Pseudophakia and polypseudophakia in the first year of life.

Wilson ME, Peterseim MW, Englert JA, Lall-Trail JK, Elliott LA.

J AAPOS. 2001 Aug;5(4):238-45.


The effect of anemia on retinopathy of prematurity in extremely low birth weight infants.

Englert JA, Saunders RA, Purohit D, Hulsey TC, Ebeling M.

J Perinatol. 2001 Jan-Feb;21(1):21-6.


In-the-bag secondary intraocular lens implantation in children.

Wilson ME Jr, Englert JA, Greenwald MJ.

J AAPOS. 1999 Dec;3(6):350-5.


The Ahmed valve in refractory pediatric glaucoma.

Englert JA, Freedman SF, Cox TA.

Am J Ophthalmol. 1999 Jan;127(1):34-42.


Argon vs diode laser trabeculoplasty.

Englert JA, Cox TA, Allingham RR, Shields MB.

Am J Ophthalmol. 1997 Nov;124(5):627-31.


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