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Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome.

Englert JA, Bobba C, Baron RM.

JCI Insight. 2019 Jan 24;4(2). pii: 124061. doi: 10.1172/jci.insight.124061. [Epub ahead of print] Review.


Sirtuin 2 enhances allergic asthmatic inflammation.

Lee YG, Reader BF, Herman D, Streicher A, Englert JA, Ziegler M, Chung S, Karpurapu M, Park GY, Christman JW, Ballinger MN.

JCI Insight. 2019 Feb 21;4(4). pii: 124710. doi: 10.1172/jci.insight.124710. eCollection 2019 Feb 21.


Whole blood RNA sequencing reveals a unique transcriptomic profile in patients with ARDS following hematopoietic stem cell transplantation.

Englert JA, Cho MH, Lamb AE, Shumyatcher M, Barragan-Bradford D, Basil MC, Higuera A, Isabelle C, Vera MP, Dieffenbach PB, Fredenburgh LE, Kang JB, Bhatt AS, Antin JH, Ho VT, Soiffer RJ, Howrylak JA, Himes BE, Baron RM.

Respir Res. 2019 Jan 21;20(1):15. doi: 10.1186/s12931-019-0981-6.


A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.

Fredenburgh LE, Perrella MA, Barragan-Bradford D, Hess DR, Peters E, Welty-Wolf KE, Kraft BD, Harris RS, Maurer R, Nakahira K, Oromendia C, Davies JD, Higuera A, Schiffer KT, Englert JA, Dieffenbach PB, Berlin DA, Lagambina S, Bouthot M, Sullivan AI, Nuccio PF, Kone MT, Malik MJ, Porras MAP, Finkelsztein E, Winkler T, Hurwitz S, Serhan CN, Piantadosi CA, Baron RM, Thompson BT, Choi AM.

JCI Insight. 2018 Dec 6;3(23). pii: 124039. doi: 10.1172/jci.insight.124039.


Prognostic Implications of Left Ventricular Hypertrophy.

Stewart MH, Lavie CJ, Shah S, Englert J, Gilliland Y, Qamruddin S, Dinshaw H, Cash M, Ventura H, Milani R.

Prog Cardiovasc Dis. 2018 Nov - Dec;61(5-6):446-455. doi: 10.1016/j.pcad.2018.11.002. Epub 2018 Nov 6. Review.


FoxO1 is a critical regulator of M2-like macrophage activation in allergic asthma.

Chung S, Kim JY, Song MA, Park GY, Lee YG, Karpurapu M, Englert JA, Ballinger MN, Pabla N, Chung HY, Christman JW.

Allergy. 2019 Mar;74(3):535-548. doi: 10.1111/all.13626. Epub 2018 Nov 5.


Tetralogy of Fallot: Case-Based Update for the Treatment of Adult Congenital Patients.

Englert JAR 3rd, Gupta T, Joury AU, Shah SB.

Curr Probl Cardiol. 2019 Feb;44(2):46-81. doi: 10.1016/j.cpcardiol.2018.03.002. Epub 2018 Mar 22. No abstract available.


Prevalence of pretreatment HIV drug resistance in Mwanza, Tanzania.

Rudovick L, Brauner JM, Englert J, Seemann C, Plugaru K, Kidenya BR, Kalluvya SE, Scheller C, Kasang C.

J Antimicrob Chemother. 2018 Dec 1;73(12):3476-3481. doi: 10.1093/jac/dky332.


Unhinging the machinery of sepsis: An unexpected role for vascular smooth muscle.

Englert JA, Christman JW, Ballinger MN.

J Leukoc Biol. 2018 Oct;104(4):661-663. doi: 10.1002/JLB.CE0618-236R. Epub 2018 Aug 22. No abstract available.


Trends in "usual care" for septic shock.

Hume PS, Varon J, Englert JA, Hurwitz S, Klompas M, Baron RM, Rhee C.

Infect Control Hosp Epidemiol. 2018 Sep;39(9):1125-1126. doi: 10.1017/ice.2018.154. Epub 2018 Jul 19. No abstract available.


Bilateral Lung Masses and Dyspnea in a Young Woman.

Hay BR, Shilo K, Englert JA.

Ann Am Thorac Soc. 2018 Jul;15(7):875-879. doi: 10.1513/AnnalsATS.201801-066CC. No abstract available.


Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models.

Leone RD, Sun IM, Oh MH, Sun IH, Wen J, Englert J, Powell JD.

Cancer Immunol Immunother. 2018 Aug;67(8):1271-1284. doi: 10.1007/s00262-018-2186-0. Epub 2018 Jun 19.


An Unexpected Expectoration.

Casey JD, Englert JA, Katz JT, Miller AL, Loscalzo J.

N Engl J Med. 2018 Mar 1;378(9):853-858. doi: 10.1056/NEJMcps1711048. No abstract available.


Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma.

Higuita-Castro N, Nelson MT, Shukla V, Agudelo-Garcia PA, Zhang W, Duarte-Sanmiguel SM, Englert JA, Lannutti JJ, Hansford DJ, Ghadiali SN.

Sci Rep. 2017 Sep 14;7(1):11623. doi: 10.1038/s41598-017-12044-9.


Zinc deficiency primes the lung for ventilator-induced injury.

Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry, Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM.

JCI Insight. 2017 Jun 2;2(11). pii: 86507. doi: 10.1172/jci.insight.86507. eCollection 2017 Jun 2.


Steroids and β-Agonists in Acute Respiratory Distress Syndrome: Timing Is Everything.

Englert JA, Crouser ED.

Crit Care Med. 2017 May;45(5):914-915. doi: 10.1097/CCM.0000000000002385. No abstract available.


Ventilator-induced lung injury increases expression of endothelial inflammatory mediators in the kidney.

Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F654-F660. doi: 10.1152/ajprenal.00523.2016. Epub 2016 Nov 9.


Interstitial Lung Abnormalities Are Associated with Acute Respiratory Distress Syndrome.

Putman RK, Hunninghake GM, Dieffenbach PB, Barragan-Bradford D, Serhan K, Adams U, Hatabu H, Nishino M, Padera RF, Fredenburgh LE, Baron RM, Englert JA.

Am J Respir Crit Care Med. 2017 Jan 1;195(1):138-141. doi: 10.1164/rccm.201604-0818LE. No abstract available.


How "mere" is the mere ownership effect in memory? Evidence for semantic organization processes.

Englert J, Wentura D.

Conscious Cogn. 2016 Nov;46:71-88. doi: 10.1016/j.concog.2016.09.007. Epub 2016 Sep 28.


Mechanical Circulatory Support for the Failing Heart: Continuous-Flow Left Ventricular Assist Devices.

Englert JA 3rd, Davis JA, Krim SR.

Ochsner J. 2016 Fall;16(3):263-9. Review.


Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.

Ghanta S, Tsoyi K, Liu X, Nakahira K, Ith B, Coronata AA, Fredenburgh LE, Englert JA, Piantadosi CA, Choi AM, Perrella MA.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):300-309. doi: 10.1165/rcmb.2016-0061OC.


Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.

Rais R, Jančařík A, Tenora L, Nedelcovych M, Alt J, Englert J, Rojas C, Le A, Elgogary A, Tan J, Monincová L, Pate K, Adams R, Ferraris D, Powell J, Majer P, Slusher BS.

J Med Chem. 2016 Sep 22;59(18):8621-33. doi: 10.1021/acs.jmedchem.6b01069. Epub 2016 Sep 6.


Hunger Pains: Stimulating the Appetite of the Immune System for Cancer.

Englert JM, Powell JD.

Cancer Cell. 2016 Jul 11;30(1):13-15. doi: 10.1016/j.ccell.2016.06.019.


Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis.

Englert JA, Rogers AJ.

Clin Chest Med. 2016 Jun;37(2):321-31. doi: 10.1016/j.ccm.2016.01.011. Epub 2016 Mar 12. Review.


Hand posture and cognitive control: The congruency sequence effect is reduced near the hands.

Englert J, Wentura D.

Psychon Bull Rev. 2016 Oct;23(5):1582-1588.


Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy.

Hou HW, Wu L, Amador-Munoz DP, Vera MP, Coronata A, Englert JA, Levy BD, Baron RM, Han J.

Lab Chip. 2016 Feb 21;16(4):688-99. doi: 10.1039/c5lc01110h. Epub 2016 Jan 15.


Isoflurane Ameliorates Acute Lung Injury by Preserving Epithelial Tight Junction Integrity.

Englert JA, Macias AA, Amador-Munoz D, Pinilla Vera M, Isabelle C, Guan J, Magaoay B, Suarez Velandia M, Coronata A, Lee A, Fredenburgh LE, Culley DJ, Crosby G, Baron RM.

Anesthesiology. 2015 Aug;123(2):377-88. doi: 10.1097/ALN.0000000000000742.


Synthesis and first X-ray structure of a hexa-peri-hexabenzocoronene-fullerene-dyad: a model for an inter-carbon-allotrope hybrid.

Kratzer A, Englert JM, Lungerich D, Heinemann FW, Jux N, Hirsch A.

Faraday Discuss. 2014;173:297-310. doi: 10.1039/c4fd00069b.


Circadian rhythm reprogramming during lung inflammation.

Haspel JA, Chettimada S, Shaik RS, Chu JH, Raby BA, Cernadas M, Carey V, Process V, Hunninghake GM, Ifedigbo E, Lederer JA, Englert J, Pelton A, Coronata A, Fredenburgh LE, Choi AM.

Nat Commun. 2014 Sep 11;5:4753. doi: 10.1038/ncomms5753.


Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products.

Milutinovic PS, Englert JM, Crum LT, Mason NS, Ramsgaard L, Enghild JJ, Sparvero LJ, Lotze MT, Oury TD.

PLoS One. 2014 Mar 18;9(3):e88259. doi: 10.1371/journal.pone.0088259. eCollection 2014.


Screening of the chemical reactivity of three different graphite sources using the formation of reductively alkylated graphene as a model reaction.

Knirsch KC, Englert JM, Dotzer C, Hauke F, Hirsch A.

Chem Commun (Camb). 2013 Nov 28;49(92):10811-3. doi: 10.1039/c3cc46621c.


Scanning-Raman-microscopy for the statistical analysis of covalently functionalized graphene.

Englert JM, Vecera P, Knirsch KC, Schäfer RA, Hauke F, Hirsch A.

ACS Nano. 2013 Jun 25;7(6):5472-82. doi: 10.1021/nn401481h. Epub 2013 May 20.


HBC-porphyrin--close contact chromophores.

Englert JM, Malig J, Zamolo VA, Hirsch A, Jux N.

Chem Commun (Camb). 2013 May 25;49(42):4827-9. doi: 10.1039/c3cc41740a.


Robust graphene membranes in a silicon carbide frame.

Waldmann D, Butz B, Bauer S, Englert JM, Jobst J, Ullmann K, Fromm F, Ammon M, Enzelberger M, Hirsch A, Maier S, Schmuki P, Seyller T, Spiecker E, Weber HB.

ACS Nano. 2013 May 28;7(5):4441-8. doi: 10.1021/nn401037c. Epub 2013 Apr 23.


On the way to graphane-pronounced fluorescence of polyhydrogenated graphene.

Schäfer RA, Englert JM, Wehrfritz P, Bauer W, Hauke F, Seyller T, Hirsch A.

Angew Chem Int Ed Engl. 2013 Jan 7;52(2):754-7. doi: 10.1002/anie.201206799. Epub 2012 Nov 26.


Statistical Raman spectroscopy: an method for the characterization of covalently functionalized single-walled carbon nanotubes.

Hof F, Bosch S, Englert JM, Hauke F, Hirsch A.

Angew Chem Int Ed Engl. 2012 Nov 19;51(47):11727-30. doi: 10.1002/anie.201204791. Epub 2012 Oct 25. No abstract available.


Visual contrast sensitivity in Alzheimer's disease, mild cognitive impairment, and older adults with cognitive complaints.

Risacher SL, Wudunn D, Pepin SM, MaGee TR, McDonald BC, Flashman LA, Wishart HA, Pixley HS, Rabin LA, Paré N, Englert JJ, Schwartz E, Curtain JR, West JD, O'Neill DP, Santulli RB, Newman RW, Saykin AJ.

Neurobiol Aging. 2013 Apr;34(4):1133-44. doi: 10.1016/j.neurobiolaging.2012.08.007. Epub 2012 Oct 18.


Wet chemical functionalization of graphene.

Hirsch A, Englert JM, Hauke F.

Acc Chem Res. 2013 Jan 15;46(1):87-96. doi: 10.1021/ar300116q. Epub 2012 Sep 4. Review.


The receptor for advanced glycation end products is a central mediator of asthma pathogenesis.

Milutinovic PS, Alcorn JF, Englert JM, Crum LT, Oury TD.

Am J Pathol. 2012 Oct;181(4):1215-25. doi: 10.1016/j.ajpath.2012.06.031. Epub 2012 Aug 11.


Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion.

Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM.

Am J Respir Cell Mol Biol. 2012 Aug;47(2):209-17. doi: 10.1165/rcmb.2011-0447OC. Epub 2012 Apr 19.


Functionalization of graphene by electrophilic alkylation of reduced graphite.

Englert JM, Knirsch KC, Dotzer C, Butz B, Hauke F, Spiecker E, Hirsch A.

Chem Commun (Camb). 2012 May 21;48(41):5025-7. doi: 10.1039/c2cc31181j. Epub 2012 Apr 17.


Chemical methods for the generation of graphenes and graphene nanoribbons.

Englert JM, Hirsch A, Feng X, Müllen K.

Angew Chem Int Ed Engl. 2011 Sep 5;50(37):A17-24.


Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.

Fredenburgh LE, Velandia MM, Ma J, Olszak T, Cernadas M, Englert JA, Chung SW, Liu X, Begay C, Padera RF, Blumberg RS, Walsh SR, Baron RM, Perrella MA.

J Immunol. 2011 Nov 15;187(10):5255-67. doi: 10.4049/jimmunol.1101186. Epub 2011 Oct 3.


Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice.

Ramsgaard L, Englert JM, Manni ML, Milutinovic PS, Gefter J, Tobolewski J, Crum L, Coudriet GM, Piganelli J, Zamora R, Vodovotz Y, Enghild JJ, Oury TD.

PLoS One. 2011;6(5):e20132. doi: 10.1371/journal.pone.0020132. Epub 2011 May 23.


A novel method for accurate collagen and biochemical assessment of pulmonary tissue utilizing one animal.

Kliment CR, Englert JM, Crum LP, Oury TD.

Int J Clin Exp Pathol. 2011 Apr;4(4):349-55. Epub 2011 Apr 12.


Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis.

Englert JM, Kliment CR, Ramsgaard L, Milutinovic PS, Crum L, Tobolewski JM, Oury TD.

Int J Clin Exp Pathol. 2011 Mar;4(3):241-54. Epub 2011 Mar 21.


Characterization of macroautophagic flux in vivo using a leupeptin-based assay.

Haspel J, Shaik RS, Ifedigbo E, Nakahira K, Dolinay T, Englert JA, Choi AM.

Autophagy. 2011 Jun;7(6):629-42. Epub 2011 Jun 1.


Covalent bulk functionalization of graphene.

Englert JM, Dotzer C, Yang G, Schmid M, Papp C, Gottfried JM, Steinrück HP, Spiecker E, Hauke F, Hirsch A.

Nat Chem. 2011 Apr;3(4):279-86. doi: 10.1038/nchem.1010. Epub 2011 Mar 20.


Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.

Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM.

Nat Immunol. 2011 Mar;12(3):222-30. doi: 10.1038/ni.1980. Epub 2010 Dec 12.


Exfoliation of hexa-peri-hexabenzocoronene in water.

Englert JM, Hauke F, Feng X, Müllen K, Hirsch A.

Chem Commun (Camb). 2010 Dec 28;46(48):9194-6. doi: 10.1039/c0cc03849k. Epub 2010 Oct 29.


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