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Items: 6

1.

Physiologically-based modeling of the pharmacokinetics of "catch-and-release" anti-carcinoembryonic antigen monoclonal antibodies in colorectal cancer xenograft mouse models.

Polli JR, Engler FA, Balthasar JP.

J Pharm Sci. 2018 Oct 12. pii: S0022-3549(18)30603-8. doi: 10.1016/j.xphs.2018.09.037. [Epub ahead of print]

PMID:
30321546
2.

"Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.

Engler FA, Polli JR, Li T, An B, Otteneder M, Qu J, Balthasar JP.

J Pharmacol Exp Ther. 2018 Jul;366(1):205-219. doi: 10.1124/jpet.117.246900. Epub 2018 May 7.

PMID:
29735609
3.

Development and validation of an enzyme-linked immunosorbent assay for the quantification of gelonin in mouse plasma.

Engler FA, Balthasar JP.

J Immunoassay Immunochem. 2016;37(6):611-22. doi: 10.1080/15321819.2016.1182551.

PMID:
27135787
4.

Investigation of the influence of nephropathy on monoclonal antibody disposition: a pharmacokinetic study in a mouse model of diabetic nephropathy.

Engler FA, Zheng B, Balthasar JP.

Pharm Res. 2014 May;31(5):1185-93. doi: 10.1007/s11095-013-1241-y. Epub 2013 Nov 8.

PMID:
24203494
5.
6.

Stabilization of a pH-sensitive apoptosis-linked coiled coil through single point mutations.

Dutta K, Engler FA, Cotton L, Alexandrov A, Bedi GS, Colquhoun J, Pascal SM.

Protein Sci. 2003 Feb;12(2):257-65.

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