Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30

1.

Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons.

Engle SJ, Blaha L, Kleiman RJ.

Neuron. 2018 Nov 21;100(4):783-797. doi: 10.1016/j.neuron.2018.10.033. Review.

PMID:
30465765
2.

Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies.

Bajaj P, Rodrigues AD, Steppan CM, Engle SJ, Mathialagan S, Schroeter T.

Drug Metab Dispos. 2018 Nov;46(11):1703-1711. doi: 10.1124/dmd.118.082727. Epub 2018 Aug 31.

PMID:
30171163
3.

Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao(-/-)) mice.

Pritchett D, Taylor AM, Barkus C, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Peirson SN, Bannerman DM.

Eur J Neurosci. 2016 Apr;43(7):979-89. doi: 10.1111/ejn.13192. Epub 2016 Mar 23.

4.

The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells.

Boisvert EM, Engle SJ, Hallowell SE, Liu P, Wang ZW, Li XJ.

Sci Rep. 2015 Nov 19;5:16821. doi: 10.1038/srep16821.

5.

d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption.

Pritchett D, Hasan S, Tam SK, Engle SJ, Brandon NJ, Sharp T, Foster RG, Harrison PJ, Bannerman DM, Peirson SN.

Eur J Neurosci. 2015 May;41(9):1167-79. doi: 10.1111/ejn.12880. Epub 2015 Mar 27.

6.

Increased burst-firing of ventral tegmental area dopaminergic neurons in D-amino acid oxidase knockout mice in vivo.

Schweimer JV, Coullon GS, Betts JF, Burnet PW, Engle SJ, Brandon NJ, Harrison PJ, Sharp T.

Eur J Neurosci. 2014 Oct;40(7):2999-3009. doi: 10.1111/ejn.12667. Epub 2014 Jul 5.

PMID:
25040393
7.

Small molecule screening in human induced pluripotent stem cell-derived terminal cell types.

Engle SJ, Vincent F.

J Biol Chem. 2014 Feb 21;289(8):4562-70. doi: 10.1074/jbc.R113.529156. Epub 2013 Dec 20. Review.

8.

Integrating human pluripotent stem cells into drug development.

Engle SJ, Puppala D.

Cell Stem Cell. 2013 Jun 6;12(6):669-77. doi: 10.1016/j.stem.2013.05.011.

9.

Comparative gene expression profiling in human-induced pluripotent stem cell--derived cardiocytes and human and cynomolgus heart tissue.

Puppala D, Collis LP, Sun SZ, Bonato V, Chen X, Anson B, Pletcher M, Fermini B, Engle SJ.

Toxicol Sci. 2013 Jan;131(1):292-301. doi: 10.1093/toxsci/kfs282. Epub 2012 Sep 14.

PMID:
22982684
10.

Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.

Rais R, Thomas AG, Wozniak K, Wu Y, Jaaro-Peled H, Sawa A, Strick CA, Engle SJ, Brandon NJ, Rojas C, Slusher BS, Tsukamoto T.

Drug Metab Dispos. 2012 Nov;40(11):2067-73. doi: 10.1124/dmd.112.046482. Epub 2012 Jul 26.

11.

Genetically engineered mouse models in drug discovery research.

Sacca R, Engle SJ, Qin W, Stock JL, McNeish JD.

Methods Mol Biol. 2010;602:37-54. doi: 10.1007/978-1-60761-058-8_3.

PMID:
20012391
12.

Generation of mice with a conditional allele for transforming growth factor beta 1 gene.

Azhar M, Yin M, Bommireddy R, Duffy JJ, Yang J, Pawlowski SA, Boivin GP, Engle SJ, Sanford LP, Grisham C, Singh RR, Babcock GF, Doetschman T.

Genesis. 2009 Jun;47(6):423-31. doi: 10.1002/dvg.20516.

13.

Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.

Prasad V, Bodi I, Meyer JW, Wang Y, Ashraf M, Engle SJ, Doetschman T, Sisco K, Nieman ML, Miller ML, Lorenz JN, Shull GE.

J Biol Chem. 2008 Nov 14;283(46):31303-14. doi: 10.1074/jbc.M803706200. Epub 2008 Sep 8.

14.

Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation.

Bommireddy R, Pathak LJ, Martin J, Ormsby I, Engle SJ, Boivin GP, Babcock GF, Eriksson AU, Singh RR, Doetschman T.

Lab Invest. 2006 Oct;86(10):1008-19. Epub 2006 Jul 24.

15.

Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice.

Bommireddy R, Engle SJ, Ormsby I, Boivin GP, Babcock GF, Doetschman T.

Cell Immunol. 2004 Nov-Dec;232(1-2):96-104. Epub 2005 Mar 29.

16.

Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice.

Engle SJ, Ormsby I, Pawlowski S, Boivin GP, Croft J, Balish E, Doetschman T.

Cancer Res. 2002 Nov 15;62(22):6362-6.

17.

Fibroblast growth factor-2 mediates pressure-induced hypertrophic response.

Schultz JE, Witt SA, Nieman ML, Reiser PJ, Engle SJ, Zhou M, Pawlowski SA, Lorenz JN, Kimball TR, Doetschman T.

J Clin Invest. 1999 Sep;104(6):709-19.

18.

Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis.

Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T.

Cancer Res. 1999 Jul 15;59(14):3379-86.

19.

Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene.

Horseman ND, Zhao W, Montecino-Rodriguez E, Tanaka M, Nakashima K, Engle SJ, Smith F, Markoff E, Dorshkind K.

EMBO J. 1997 Dec 1;16(23):6926-35.

20.

The logic of signaling from the cell surface to the nucleus.

Horseman ND, Engle SJ, Ralescu A.

Trends Endocrinol Metab. 1997 May-Jun;8(4):123-9.

PMID:
18406797
21.

Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice.

Tian M, Broxmeyer HE, Fan Y, Lai Z, Zhang S, Aronica S, Cooper S, Bigsby RM, Steinmetz R, Engle SJ, Mestek A, Pollock JD, Lehman MN, Jansen HT, Ying M, Stambrook PJ, Tischfield JA, Yu L.

J Exp Med. 1997 Apr 21;185(8):1517-22.

22.

HPRT-APRT-deficient mice are not a model for lesch-nyhan syndrome.

Engle SJ, Womer DE, Davies PM, Boivin G, Sahota A, Simmonds HA, Stambrook PJ, Tischfield JA.

Hum Mol Genet. 1996 Oct;5(10):1607-10.

PMID:
8894695
23.

Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis.

Engle SJ, Stockelman MG, Chen J, Boivin G, Yum MN, Davies PM, Ying MY, Sahota A, Simmonds HA, Stambrook PJ, Tischfield JA.

Proc Natl Acad Sci U S A. 1996 May 28;93(11):5307-12.

24.

Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human.

Tischfield JA, Xia YR, Shih DM, Klisak I, Chen J, Engle SJ, Siakotos AN, Winstead MV, Seilhamer JJ, Allamand V, Gyapay G, Lusis AJ.

Genomics. 1996 Mar 15;32(3):328-33.

PMID:
8838795
25.

APRT: a versatile in vivo resident reporter of local mutation and loss of heterozygosity.

Stambrook PJ, Shao C, Stockelman M, Boivin G, Engle SJ, Tischfield JA.

Environ Mol Mutagen. 1996;28(4):471-82.

PMID:
8991080
26.

Cloning, expression and partial characterization of a novel rat phospholipase A2.

Chen J, Engle SJ, Seilhamer JJ, Tischfield JA.

Biochim Biophys Acta. 1994 Nov 17;1215(1-2):115-20.

PMID:
7947992
27.
28.

Cloning and recombinant expression of a novel human low molecular weight Ca(2+)-dependent phospholipase A2.

Chen J, Engle SJ, Seilhamer JJ, Tischfield JA.

J Biol Chem. 1994 Jan 28;269(4):2365-8.

29.

Germline and somatic mutation at the APRT locus of mice and man.

Tischfield JA, Engle SJ, Gupta PK, Bye S, Boyadjiev S, Shao C, O'Neill P, Albertini RJ, Stambrook PJ, Sahota AS.

Adv Exp Med Biol. 1994;370:661-4. Review. No abstract available.

PMID:
7660991
30.

Mitral valve E point to ventricular septal separation in infants and children.

Engle SJ, DiSessa TG, Perloff JK, Isabel-Jones J, Leighton J, Gross K, Friedman WF.

Am J Cardiol. 1983 Nov 1;52(8):1084-7.

PMID:
6637828

Supplemental Content

Loading ...
Support Center