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Chirality-driven transportation and oxidation prevention by chiral selenium nanoparticles.

Huang Y, Fu Y, Li M, Jiang D, Kutyreff CJ, Engle JW, Lan X, Cai W, Chen T.

Angew Chem Int Ed Engl. 2019 Dec 25. doi: 10.1002/anie.201910615. [Epub ahead of print]


177Lu-NM600 targeted radionuclide therapy extends survival in syngeneic murine models of triple-negative breast cancer.

Hernandez R, Grudzinski JJ, Aluicio-Sarduy E, Massey CF, Pinchuk AN, Bitton AN, Patel R, Zhang R, Kumar AV, Iyer G, Engle JW, Weichert JP.

J Nucl Med. 2019 Dec 20. pii: jnumed.119.236265. doi: 10.2967/jnumed.119.236265. [Epub ahead of print]


Surfactant-Stripped Pheophytin Micelles for Multimodal Tumor Imaging and Photodynamic Therapy.

Moukheiber D, Chitgupi U, Carter KA, Luo D, Sun B, Goel S, Ferreira CA, Engle JW, Wang D, Geng J, Zhang Y, Xia J, Cai W, Lovell JF.

ACS Appl Bio Mater. 2019 Jan 22;2(1):544-554. doi: 10.1021/acsabm.8b00703. Epub 2018 Dec 19.


Auditory Processing Deficits Are Selectively Associated with Medial Temporal Lobe Mnemonic Function and White Matter Integrity in Aging Macaques.

Gray DT, Umapathy L, De La Peña NM, Burke SN, Engle JR, Trouard TP, Barnes CA.

Cereb Cortex. 2019 Dec 13. pii: bhz275. doi: 10.1093/cercor/bhz275. [Epub ahead of print]


HER2-targeted multimodal imaging of anaplastic thyroid cancer.

Wei W, Jiang D, Rosenkrans ZT, Barnhart TE, Engle JW, Luo Q, Cai W.

Am J Cancer Res. 2019 Nov 1;9(11):2413-2427. eCollection 2019.


Self-amplified Photodynamic Therapy through 1O2-mediated In Situ Internalization of Photosensitizers from a Ppa-bearing Block Copolymer.

Liu Z, Cao T, Xue Y, Li M, Wu M, Engle JW, He Q, Cai W, Lan M, Zhang W.

Angew Chem Int Ed Engl. 2019 Dec 6. doi: 10.1002/anie.201914434. [Epub ahead of print]


Evolutionarily conserved regulation of sleep by epidermal growth factor receptor signaling.

Lee DA, Liu J, Hong Y, Lane JM, Hill AJ, Hou SL, Wang H, Oikonomou G, Pham U, Engle J, Saxena R, Prober DA.

Sci Adv. 2019 Nov 13;5(11):eaax4249. doi: 10.1126/sciadv.aax4249. eCollection 2019 Nov.


Establishing Radiolanthanum Chemistry for Targeted Nuclear Medicine Applications.

Aluicio-Sarduy E, Thiele NA, Martin KE, Vaughn BA, Devaraj J, Olson AP, Barnhart TE, Wilson JJ, Boros E, Engle JW.

Chemistry. 2019 Nov 19. doi: 10.1002/chem.201905202. [Epub ahead of print]


A "Missile-Detonation" Strategy to Precisely Supply and Efficiently Amplify Cerenkov Radiation Energy for Cancer Theranostics.

Yu B, Ni D, Rosenkrans ZT, Barnhart TE, Wei H, Ferreira CA, Lan X, Engle JW, He Q, Yu F, Cai W.

Adv Mater. 2019 Dec;31(52):e1904894. doi: 10.1002/adma.201904894. Epub 2019 Nov 11.


ImmunoPET imaging of CD38 expression in hepatocellular carcinoma using 64Cu-labeled daratumumab.

Li S, England CG, Ehlerding EB, Kutyreff CJ, Engle JW, Jiang D, Cai W.

Am J Transl Res. 2019 Sep 15;11(9):6007-6015. eCollection 2019.


Intrathecal Administration of Nanoclusters for Protecting Neurons against Oxidative Stress in Cerebral Ischemia/Reperfusion Injury.

Li S, Jiang D, Ehlerding EB, Rosenkrans ZT, Engle JW, Wang Y, Liu H, Ni D, Cai W.

ACS Nano. 2019 Nov 26;13(11):13382-13389. doi: 10.1021/acsnano.9b06780. Epub 2019 Oct 15.


Immuno-PET imaging of VEGFR-2 expression in prostate cancer with 89Zr-labeled ramucirumab.

Li M, Jiang D, Barnhart TE, Cao T, Engle JW, Chen W, Cai W.

Am J Cancer Res. 2019 Sep 1;9(9):2037-2046. eCollection 2019.


Improved production of 76Br, 77Br and 80mBr via CoSe cyclotron targets and vertical dry distillation.

Ellison PA, Olson AP, Barnhart TE, Hoffman SLV, Reilly SW, Makvandi M, Bartels JL, Murali D, DeJesus OT, Lapi SE, Bednarz B, Nickles RJ, Mach RH, Engle JW.

Nucl Med Biol. 2019 Sep 5. pii: S0969-8051(19)30162-3. doi: 10.1016/j.nucmedbio.2019.09.001. [Epub ahead of print]


Size-Optimized Ultrasmall Porous Silica Nanoparticles Depict Vasculature-Based Differential Targeting in Triple Negative Breast Cancer.

Goel S, Ferreira CA, Dogra P, Yu B, Kutyreff CJ, Siamof CM, Engle JW, Barnhart TE, Cristini V, Wang Z, Cai W.

Small. 2019 Nov;15(46):e1903747. doi: 10.1002/smll.201903747. Epub 2019 Sep 29.


Aptamer-Conjugated Framework Nucleic Acids for the Repair of Cerebral Ischemia-Reperfusion Injury.

Li S, Jiang D, Rosenkrans ZT, Barnhart TE, Ehlerding EB, Ni D, Engle JW, Cai W.

Nano Lett. 2019 Oct 9;19(10):7334-7341. doi: 10.1021/acs.nanolett.9b02958. Epub 2019 Sep 13.


A Model of Prefilled Syringes Exposure to Vapor Phase Hydrogen Peroxide (VPHP).

Downey D, McGarvey B, Walsh M, Engle J.

PDA J Pharm Sci Technol. 2019 Aug 16. pii: pdajpst.2018.009431. doi: 10.5731/pdajpst.2018.009431. [Epub ahead of print]


Ceria Nanoparticles Meet Hepatic Ischemia-Reperfusion Injury: The Perfect Imperfection.

Ni D, Wei H, Chen W, Bao Q, Rosenkrans ZT, Barnhart TE, Ferreira CA, Wang Y, Yao H, Sun T, Jiang D, Li S, Cao T, Liu Z, Engle JW, Hu P, Lan X, Cai W.

Adv Mater. 2019 Oct;31(40):e1902956. doi: 10.1002/adma.201902956. Epub 2019 Aug 16.


Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection.

Lee HJ, Ehlerding EB, Jiang D, Barnhart TE, Cao T, Wei W, Ferreira CA, Huang P, Engle JW, Cai W.

Am J Cancer Res. 2019 Jul 1;9(7):1454-1468. eCollection 2019.


PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder.

Schneider ML, Moore CF, Ahlers EO, Barnhart TE, Christian BT, DeJesus OT, Engle JW, Holden JE, Larson JA, Moirano JM, Murali D, Nickles RJ, Resch LM, Converse AK.

Front Integr Neurosci. 2019 Jul 17;13:29. doi: 10.3389/fnint.2019.00029. eCollection 2019.


Production and in vivo PET/CT imaging of the theranostic pair 132/135La.

Aluicio-Sarduy E, Hernandez R, Olson AP, Barnhart TE, Cai W, Ellison PA, Engle JW.

Sci Rep. 2019 Jul 23;9(1):10658. doi: 10.1038/s41598-019-47137-0.


CD146-Targeted Multimodal Image-Guided Photoimmunotherapy of Melanoma.

Wei W, Jiang D, Ehlerding EB, Barnhart TE, Yang Y, Engle JW, Luo QY, Huang P, Cai W.

Adv Sci (Weinh). 2019 Feb 27;6(9):1801237. doi: 10.1002/advs.201801237. eCollection 2019 May 3.


Noninvasive Imaging and Quantification of Radiotherapy-Induced PD-L1 Upregulation with 89Zr-Df-Atezolizumab.

Ehlerding EB, Lee HJ, Barnhart TE, Jiang D, Kang L, McNeel DG, Engle JW, Cai W.

Bioconjug Chem. 2019 May 15;30(5):1434-1441. doi: 10.1021/acs.bioconjchem.9b00178. Epub 2019 Apr 19.


Preclinical Characterization of 86/90Y-NM600 in a Variety of Murine and Human Cancer Tumor Models.

Grudzinski JJ, Hernandez R, Marsh I, Patel RB, Aluicio-Sarduy E, Engle J, Morris Z, Bednarz B, Weichert J.

J Nucl Med. 2019 Nov;60(11):1622-1628. doi: 10.2967/jnumed.118.224808. Epub 2019 Apr 6.


Large-Scale Production of 119mTe and 119Sb for Radiopharmaceutical Applications.

Bennett KT, Bone SE, Akin AC, Birnbaum ER, Blake AV, Brugh M, Daly SR, Engle JW, Fassbender ME, Ferrier MG, Kozimor SA, Lilley LM, Martinez CA, Mocko V, Nortier FM, Stein BW, Thiemann SL, Vermeulen C.

ACS Cent Sci. 2019 Mar 27;5(3):494-505. doi: 10.1021/acscentsci.8b00869. Epub 2019 Feb 25.


PET of Poly (ADP-Ribose) Polymerase Activity in Cancer: Preclinical Assessment and First In-Human Studies.

Michel LS, Dyroff S, Brooks FJ, Spayd KJ, Lim S, Engle JT, Phillips S, Tan B, Wang-Gillam A, Bognar C, Chu W, Zhou D, Mach RH, Laforest R, Chen DL.

Radiology. 2019 Apr;291(1):271. doi: 10.1148/radiol.2019194006. No abstract available.


Site-Specific Immuno-PET Tracer to Image PD-L1.

Wissler HL, Ehlerding EB, Lyu Z, Zhao Y, Zhang S, Eshraghi A, Buuh ZY, McGuth JC, Guan Y, Engle JW, Bartlett SJ, Voelz VA, Cai W, Wang RE.

Mol Pharm. 2019 May 6;16(5):2028-2036. doi: 10.1021/acs.molpharmaceut.9b00010. Epub 2019 Mar 25.


Effects of motivation phase intervention components on quit attempts in smokers unwilling to quit: A factorial experiment.

Engle JL, Mermelstein R, Baker TB, Smith SS, Schlam TR, Piper ME, Jorenby DE, Collins LM, Cook JW.

Drug Alcohol Depend. 2019 Apr 1;197:149-157. doi: 10.1016/j.drugalcdep.2019.01.011. Epub 2019 Feb 16.


90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin's Lymphoma.

Hernandez R, Walker KL, Grudzinski JJ, Aluicio-Sarduy E, Patel R, Zahm CD, Pinchuk AN, Massey CF, Bitton AN, Brown RJ, Sondel PM, Morris ZS, Engle JW, Capitini CM, Weichert JP.

Commun Biol. 2019 Feb 26;2:79. doi: 10.1038/s42003-019-0327-4. eCollection 2019.


Radiochemical isolation method for the production of 52gMn from natCr for accelerator targets.

Barrett KE, Aluicio-Sarduy E, Olson AP, Kutyreff CJ, Ellison PA, Barnhart TE, Nickles RJ, Engle JW.

Appl Radiat Isot. 2019 Apr;146:99-103. doi: 10.1016/j.apradiso.2019.01.025. Epub 2019 Feb 1.


Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models.

Ehlerding EB, Lee HJ, Jiang D, Ferreira CA, Zahm CD, Huang P, Engle JW, McNeel DG, Cai W.

Am J Cancer Res. 2019 Jan 1;9(1):53-63. eCollection 2019.


Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice.

Ni D, Jiang D, Kutyreff CJ, Lai J, Yan Y, Barnhart TE, Yu B, Im HJ, Kang L, Cho SY, Liu Z, Huang P, Engle JW, Cai W.

Nat Commun. 2018 Dec 21;9(1):5421. doi: 10.1038/s41467-018-07890-8.


DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury.

Jiang D, Ge Z, Im HJ, England CG, Ni D, Hou J, Zhang L, Kutyreff CJ, Yan Y, Liu Y, Cho SY, Engle JW, Shi J, Huang P, Fan C, Yan H, Cai W.

Nat Biomed Eng. 2018 Nov;2(11):865-877. doi: 10.1038/s41551-018-0317-8. Epub 2018 Nov 8.


In Vivo Tumor-Targeted Dual-Modality PET/Optical Imaging with a Yolk/Shell-Structured Silica Nanosystem.

Shi S, Chen F, Goel S, Graves SA, Luo H, Theuer CP, Engle JW, Cai W.

Nanomicro Lett. 2018;10(4):65. doi: 10.1007/s40820-018-0216-2. Epub 2018 Jul 16.


Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy.

Ni D, Ferreira CA, Barnhart TE, Quach V, Yu B, Jiang D, Wei W, Liu H, Engle JW, Hu P, Cai W.

J Am Chem Soc. 2018 Nov 7;140(44):14971-14979. doi: 10.1021/jacs.8b09374. Epub 2018 Oct 29.


Simplified and automatable radiochemical separation strategy for the production of radiopharmaceutical quality 86Y using single column extraction chromatography.

Aluicio-Sarduy E, Hernandez R, Valdovinos HF, Kutyreff CJ, Ellison PA, Barnhart TE, Nickles RJ, Engle JW.

Appl Radiat Isot. 2018 Dec;142:28-31. doi: 10.1016/j.apradiso.2018.09.016. Epub 2018 Sep 14.


Saccadic impairment in chronic traumatic brain injury: examining the influence of cognitive load and injury severity.

Ettenhofer ML, Hershaw JN, Engle JR, Hungerford LD.

Brain Inj. 2018;32(13-14):1740-1748. doi: 10.1080/02699052.2018.1511067. Epub 2018 Sep 5.


Correction to Renal-Clearable Ultrasmall Coordination Polymer Nanodots for Chelator-Free 64Cu-Labeling and Imaging-Guided Enhanced Radiotherapy of Cancer.

Shen S, Jiang D, Cheng L, Chao Y, Nie K, Dong Z, Kutyreff CJ, Engle JW, Huang P, Cai W, Liu Z.

ACS Nano. 2018 Sep 25;12(9):9633. doi: 10.1021/acsnano.8b04084. Epub 2018 Aug 22. No abstract available.


Lone-Pair-Induced Topicity Observed in Macrobicyclic Tetra-thia Lactams and Cryptands: Synthesis, Spectral Identification, and Computational Assessment.

Walker TL, Taschner IS, Chandra M S, Taschner MJ, Engle JT, Schrage BR, Ziegler CJ, Gao X, Wheeler SE.

J Org Chem. 2018 Sep 7;83(17):10025-10036. doi: 10.1021/acs.joc.8b01382. Epub 2018 Aug 1.


Evaluation of a chloride-based 89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin.

Graves SA, Kutyreff C, Barrett KE, Hernandez R, Ellison PA, Happel S, Aluicio-Sarduy E, Barnhart TE, Nickles RJ, Engle JW.

Nucl Med Biol. 2018 Sep - Oct;64-65:1-7. doi: 10.1016/j.nucmedbio.2018.06.003. Epub 2018 Jun 18.


ImmunoPET of CD146 in a Murine Hindlimb Ischemia Model.

Ferreira CA, Hernandez R, Yang Y, Valdovinos HF, Engle JW, Cai W.

Mol Pharm. 2018 Aug 6;15(8):3434-3441. doi: 10.1021/acs.molpharmaceut.8b00424. Epub 2018 Jun 25.


Intrinsically Zirconium-89-Labeled Manganese Oxide Nanoparticles for In Vivo Dual-Modality Positron Emission Tomography and Magnetic Resonance Imaging.

Zhan Y, Ehlerding EB, Shi S, Graves SA, Goel S, Engle JW, Liang J, Cai W.

J Biomed Nanotechnol. 2018 May 1;14(5):900-909. doi: 10.1166/jbn.2018.2498.


86/90Y-Based Theranostics Targeting Angiogenesis in a Murine Breast Cancer Model.

Ehlerding EB, Ferreira CA, Aluicio-Sarduy E, Jiang D, Lee HJ, Theuer CP, Engle JW, Cai W.

Mol Pharm. 2018 Jul 2;15(7):2606-2613. doi: 10.1021/acs.molpharmaceut.8b00133. Epub 2018 May 30.


The Production of Ac-225.

Engle JW.

Curr Radiopharm. 2018;11(3):173-179. doi: 10.2174/1874471011666180418141357. Review.


Large-scale impacts of sea star wasting disease (SSWD) on intertidal sea stars and implications for recovery.

Miner CM, Burnaford JL, Ambrose RF, Antrim L, Bohlmann H, Blanchette CA, Engle JM, Fradkin SC, Gaddam R, Harley CDG, Miner BG, Murray SN, Smith JR, Whitaker SG, Raimondi PT.

PLoS One. 2018 Mar 20;13(3):e0192870. doi: 10.1371/journal.pone.0192870. eCollection 2018.


Noninvasive Trafficking of Brentuximab Vedotin and PET Imaging of CD30 in Lung Cancer Murine Models.

Kang L, Jiang D, Ehlerding EB, Barnhart TE, Ni D, Engle JW, Wang R, Huang P, Xu X, Cai W.

Mol Pharm. 2018 Apr 2;15(4):1627-1634. doi: 10.1021/acs.molpharmaceut.7b01168. Epub 2018 Mar 20.


ImmunoPET imaging of CD38 in murine lymphoma models using 89Zr-labeled daratumumab.

Kang L, Jiang D, England CG, Barnhart TE, Yu B, Rosenkrans ZT, Wang R, Engle JW, Xu X, Huang P, Cai W.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1372-1381. doi: 10.1007/s00259-018-3941-3. Epub 2018 Feb 15.


Alpha-Emitters and Targeted Alpha Therapy in Oncology: from Basic Science to Clinical Investigations.

Makvandi M, Dupis E, Engle JW, Nortier FM, Fassbender ME, Simon S, Birnbaum ER, Atcher RW, John KD, Rixe O, Norenberg JP.

Target Oncol. 2018 Apr;13(2):189-203. doi: 10.1007/s11523-018-0550-9. Review.


The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study.

Chen DL, Huang HJ, Byers DE, Shifren A, Belikoff B, Engle JT, Arentson E, Kemp D, Phillips S, Scherrer DE, Fujiwara H, Spayd KJ, Brooks FJ, Pierce RA, Castro M, Isakow W.

PLoS One. 2018 Feb 7;13(2):e0191783. doi: 10.1371/journal.pone.0191783. eCollection 2018.


PET radiometals for antibody labeling.

Aluicio-Sarduy E, Ellison PA, Barnhart TE, Cai W, Nickles RJ, Engle JW.

J Labelled Comp Radiopharm. 2018 Jul;61(9):636-651. doi: 10.1002/jlcr.3607. Epub 2018 Mar 12. Review.


Size, growth, and density data for shallow-water sea urchins from Mexico to the Aleutian Islands, Alaska, 1956-2016.

Ebert TA, Barr LM, Bodkin JL, Burcham D, Bureau D, Carson HS, L Caruso N, Caselle JE, Claisse JT, Clemente S, Davis K, Detwiler PM, Dixon JD, Duggins DO, Engle JM, Estes JA, Groth SD, Grupe BM, Halmay P, Hebert KP, Hernández JC, Jurgens LJ, Kalvass PE, Kenner MC, Konar B, Kushner DJ, Lee LC, Leighton DL, Montaño-Moctezuma G, Eric Munk J, Olguin I, Palleiro JS, Parker DO, Pearse JS, Pondella DJ, Rogers-Bennett L, Schroeter SC, Shelton AO, Sonnenholzner J, Taniguchi IK, VanBlaricom GR, Watson JC, Weitzman BP, Williams JP, Yakimishyn J, Zhang Z.

Ecology. 2018 Mar;99(3):761. doi: 10.1002/ecy.2123. Epub 2018 Jan 23.


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