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Items: 8


Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.

Deng G, Shen J, Yin M, McManus J, Mathieu M, Gee P, He T, Shi C, Bedel O, McLean LR, Le-Strat F, Zhang Y, Marquette JP, Gao Q, Zhang B, Rak A, Hoffmann D, Rooney E, Vassort A, Englaro W, Li Y, Patel V, Adrian F, Gross S, Wiederschain D, Cheng H, Licht S.

J Biol Chem. 2015 Jan 9;290(2):762-74. doi: 10.1074/jbc.M114.608497. Epub 2014 Nov 12.


Regulation of C2C12 myogenic terminal differentiation by MKK3/p38alpha pathway.

Cabane C, Englaro W, Yeow K, Ragno M, Dérijard B.

Am J Physiol Cell Physiol. 2003 Mar;284(3):C658-66. Epub 2002 Nov 20.


Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.

Desreumaux P, Dubuquoy L, Nutten S, Peuchmaur M, Englaro W, Schoonjans K, Derijard B, Desvergne B, Wahli W, Chambon P, Leibowitz MD, Colombel JF, Auwerx J.

J Exp Med. 2001 Apr 2;193(7):827-38.


Tumor necrosis factor alpha-mediated inhibition of melanogenesis is dependent on nuclear factor kappa B activation.

Englaro W, Bahadoran P, Bertolotto C, Buscà R, Dérijard B, Livolsi A, Peyron JF, Ortonne JP, Ballotti R.

Oncogene. 1999 Feb 25;18(8):1553-9.


Inhibition of Rho is required for cAMP-induced melanoma cell differentiation.

Buscà R, Bertolotto C, Abbe P, Englaro W, Ishizaki T, Narumiya S, Boquet P, Ortonne JP, Ballotti R.

Mol Biol Cell. 1998 Jun;9(6):1367-78.


Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.

Englaro W, Bertolotto C, Buscà R, Brunet A, Pagès G, Ortonne JP, Ballotti R.

J Biol Chem. 1998 Apr 17;273(16):9966-70.


Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP-induced melanogenesis in B-16 melanoma cells.

Englaro W, Rezzonico R, Durand-Clément M, Lallemand D, Ortonne JP, Ballotti R.

J Biol Chem. 1995 Oct 13;270(41):24315-20.

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