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Items: 1 to 50 of 169

1.

Deaf patient-provider communication and lung cancer screening: Health Information National Trends survey in American Sign Language (HINTS-ASL).

Kushalnagar P, Engelman A, Sadler G.

Patient Educ Couns. 2018 Jul;101(7):1232-1239. doi: 10.1016/j.pec.2018.03.003. Epub 2018 Mar 5.

PMID:
29548598
2.

Cellular and molecular mechanisms of HIV-1 integration targeting.

Engelman AN, Singh PK.

Cell Mol Life Sci. 2018 Jul;75(14):2491-2507. doi: 10.1007/s00018-018-2772-5. Epub 2018 Feb 7. Review.

PMID:
29417178
3.

Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.

Zhu Y, Wang X, Forouzmand E, Jeong J, Qiao F, Sowd GA, Engelman AN, Xie X, Hertel KJ, Shi Y.

Mol Cell. 2018 Jan 4;69(1):62-74.e4. doi: 10.1016/j.molcel.2017.11.031. Epub 2017 Dec 21.

PMID:
29276085
4.

Multiplex single-cell visualization of nucleic acids and protein during HIV infection.

Puray-Chavez M, Tedbury PR, Huber AD, Ukah OB, Yapo V, Liu D, Ji J, Wolf JJ, Engelman AN, Sarafianos SG.

Nat Commun. 2017 Dec 1;8(1):1882. doi: 10.1038/s41467-017-01693-z.

5.

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.

El Ashkar S, Schwaller J, Pieters T, Goossens S, Demeulemeester J, Christ F, Van Belle S, Juge S, Boeckx N, Engelman A, Van Vlierberghe P, Debyser Z, De Rijck J.

Blood. 2018 Jan 4;131(1):95-107. doi: 10.1182/blood-2017-05-786962. Epub 2017 Oct 30.

6.

Epidemiology, diagnosis, and optimal management of glioma in adolescents and young adults.

Diwanji TP, Engelman A, Snider JW, Mohindra P.

Adolesc Health Med Ther. 2017 Sep 22;8:99-113. doi: 10.2147/AHMT.S53391. eCollection 2017. Review.

7.

Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.

Hoyte AC, Jamin AV, Koneru PC, Kobe MJ, Larue RC, Fuchs JR, Engelman AN, Kvaratskhelia M.

J Biol Chem. 2017 Dec 1;292(48):19814-19825. doi: 10.1074/jbc.M117.816645. Epub 2017 Sep 28.

PMID:
28972144
8.

CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.

Alvarez FJD, He S, Perilla JR, Jang S, Schulten K, Engelman AN, Scheres SHW, Zhang P.

Sci Adv. 2017 Sep 15;3(9):e1701264. doi: 10.1126/sciadv.1701264. eCollection 2017 Sep.

9.

Risk perception and perceived self-efficacy of deaf and hard-of-hearing seniors and young adults in emergencies.

Engelman A, Ivey SL, Tseng W, Neuhauser L.

Am J Disaster Med. 2017 Winter;12(1):43-60. doi: 10.5055/ajdm.2017.0257.

PMID:
28822214
10.

Capsid-Dependent Host Factors in HIV-1 Infection.

Yamashita M, Engelman AN.

Trends Microbiol. 2017 Sep;25(9):741-755. doi: 10.1016/j.tim.2017.04.004. Epub 2017 May 18. Review.

PMID:
28528781
11.

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.

Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.

12.

Structural basis for spumavirus GAG tethering to chromatin.

Lesbats P, Serrao E, Maskell DP, Pye VE, O'Reilly N, Lindemann D, Engelman AN, Cherepanov P.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5509-5514. doi: 10.1073/pnas.1621159114. Epub 2017 May 10.

13.

Retroviral intasomes arising.

Engelman AN, Cherepanov P.

Curr Opin Struct Biol. 2017 Dec;47:23-29. doi: 10.1016/j.sbi.2017.04.005. Epub 2017 Apr 28. Review.

14.

Risk perception and perceived self-efficacy of deaf and hard-of-hearing seniors and young adults in emergencies.

Engelman A, Ivey SL, Tseng W, Neuhauser L.

J Emerg Manag. 2017 Jan/Feb;15(1):7-15. doi: 10.5055/jem.2017.0309.

PMID:
28345748
15.

Retroviral integrase protein and intasome nucleoprotein complex structures.

Grawenhoff J, Engelman AN.

World J Biol Chem. 2017 Feb 26;8(1):32-44. doi: 10.4331/wjbc.v8.i1.32. Review.

16.

Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.

Wang W, Zhou J, Halambage UD, Jurado KA, Jamin AV, Wang Y, Engelman AN, Aiken C.

J Virol. 2017 Apr 13;91(9). pii: e02155-16. doi: 10.1128/JVI.02155-16. Print 2017 May 1.

17.

A supramolecular assembly mediates lentiviral DNA integration.

Ballandras-Colas A, Maskell DP, Serrao E, Locke J, Swuec P, Jónsson SR, Kotecha A, Cook NJ, Pye VE, Taylor IA, Andrésdóttir V, Engelman AN, Costa A, Cherepanov P.

Science. 2017 Jan 6;355(6320):93-95. doi: 10.1126/science.aah7002.

18.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.

Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ.

Cell Rep. 2016 Dec 20;17(12):3178-3192. doi: 10.1016/j.celrep.2016.11.077.

19.

Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA).

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

JAMA Oncol. 2017 Jun 1;3(6):827-831. doi: 10.1001/jamaoncol.2016.3834.

20.

Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies.

Deng N, Hoyte A, Mansour YE, Mohamed MS, Fuchs JR, Engelman AN, Kvaratskhelia M, Levy R.

Protein Sci. 2016 Nov;25(11):1911-1917. doi: 10.1002/pro.2997. Epub 2016 Aug 17.

21.

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

Zurnic I, Hütter S, Rzeha U, Helbig R, Stanke N, Reh J, Müllers E, Hamann MV, Kern T, Gerresheim GK, Lindel F, Serrao E, Lesbats P, Engelman AN, Cherepanov P, Lindemann D.

PLoS Pathog. 2016 Oct 10;12(10):e1005956. doi: 10.1371/journal.ppat.1005956. eCollection 2016 Oct.

22.

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.

Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E.

J Biol Chem. 2016 Nov 4;291(45):23569-23577. Epub 2016 Sep 19.

23.

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases.

Sperduto PW, Yang TJ, Beal K, Pan H, Brown PD, Bangdiwala A, Shanley R, Yeh N, Gaspar LE, Braunstein S, Sneed P, Boyle J, Kirkpatrick JP, Mak KS, Shih HA, Engelman A, Roberge D, Arvold ND, Alexander B, Awad MM, Contessa J, Chiang V, Hardie J, Ma D, Lou E, Sperduto W, Mehta MP.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):406-413. doi: 10.1016/j.ijrobp.2016.06.006. Epub 2016 Jun 14.

24.

Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

Zurnic I, Hütter S, Rzeha U, Stanke N, Reh J, Müllers E, Hamann MV, Kern T, Gerresheim GK, Lindel F, Serrao E, Lesbats P, Engelman AN, Cherepanov P, Lindemann D.

PLoS Pathog. 2016 Aug 31;12(8):e1005860. doi: 10.1371/journal.ppat.1005860. eCollection 2016 Aug. Erratum in: PLoS Pathog. 2016 Oct 10;12 (10 ):e1005956.

25.

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.

Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N.

J Virol. 2016 Aug 26;90(18):8059-73. doi: 10.1128/JVI.00553-16. Print 2016 Sep 15.

26.

Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.

Saito A, Henning MS, Serrao E, Dubose BN, Teng S, Huang J, Li X, Saito N, Roy SP, Siddiqui MA, Ahn J, Tsuji M, Hatziioannou T, Engelman AN, Yamashita M.

J Virol. 2016 Jul 11;90(15):6918-6935. doi: 10.1128/JVI.00019-16. Print 2016 Aug 1.

27.

Retroviral DNA Integration.

Lesbats P, Engelman AN, Cherepanov P.

Chem Rev. 2016 Oct 26;116(20):12730-12757. doi: 10.1021/acs.chemrev.6b00125. Epub 2016 May 20. Review.

28.

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.

Saito A, Ferhadian D, Sowd GA, Serrao E, Shi J, Halambage UD, Teng S, Soto J, Siddiqui MA, Engelman AN, Aiken C, Yamashita M.

J Virol. 2016 May 27;90(12):5808-5823. doi: 10.1128/JVI.03116-15. Print 2016 Jun 15.

29.

Prognostic significance of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients treated with selective internal radiation therapy.

D'Emic N, Engelman A, Molitoris J, Hanlon A, Sharma NK, Moeslein FM, Chuong MD.

J Gastrointest Oncol. 2016 Apr;7(2):269-77. doi: 10.3978/j.issn.2078-6891.2015.108.

30.

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.

Serrao E, Cherepanov P, Engelman AN.

J Vis Exp. 2016 Mar 22;(109). doi: 10.3791/53840.

31.

The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes.

Rasheedi S, Shun MC, Serrao E, Sowd GA, Qian J, Hao C, Dasgupta T, Engelman AN, Skowronski J.

J Biol Chem. 2016 May 27;291(22):11809-19. doi: 10.1074/jbc.M116.721647. Epub 2016 Mar 18.

32.

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.

Feng L, Dharmarajan V, Serrao E, Hoyte A, Larue RC, Slaughter A, Sharma A, Plumb MR, Kessl JJ, Fuchs JR, Bushman FD, Engelman AN, Griffin PR, Kvaratskhelia M.

ACS Chem Biol. 2016 May 20;11(5):1313-21. doi: 10.1021/acschembio.6b00167. Epub 2016 Mar 2.

33.

Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.

Ballandras-Colas A, Brown M, Cook NJ, Dewdney TG, Demeler B, Cherepanov P, Lyumkis D, Engelman AN.

Nature. 2016 Feb 18;530(7590):358-61. doi: 10.1038/nature16955.

34.

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

Sowd GA, Serrao E, Wang H, Wang W, Fadel HJ, Poeschla EM, Engelman AN.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1054-63. doi: 10.1073/pnas.1524213113. Epub 2016 Feb 8.

35.

Cultural Competence Training for Law Enforcement Responding to Domestic Violence Emergencies With the Deaf and Hard of Hearing: A Mixed-Methods Evaluation.

Engelman A, Deardorff J.

Health Promot Pract. 2016 Mar;17(2):177-85. doi: 10.1177/1524839915621538. Epub 2015 Dec 28.

PMID:
26715697
36.

Sites of retroviral DNA integration: From basic research to clinical applications.

Serrao E, Engelman AN.

Crit Rev Biochem Mol Biol. 2016;51(1):26-42. doi: 10.3109/10409238.2015.1102859. Epub 2015 Oct 28. Review.

37.

Foreign DNA capture during CRISPR-Cas adaptive immunity.

Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA.

Nature. 2015 Nov 26;527(7579):535-8. doi: 10.1038/nature15760. Epub 2015 Oct 21.

38.

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.

Wang H, Shun MC, Dickson AK, Engelman AN.

PLoS One. 2015 Sep 14;10(9):e0137797. doi: 10.1371/journal.pone.0137797. eCollection 2015.

39.

Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation.

Fontana J, Jurado KA, Cheng N, Ly NL, Fuchs JR, Gorelick RJ, Engelman AN, Steven AC.

J Virol. 2015 Oct;89(19):9765-80. doi: 10.1128/JVI.01522-15. Epub 2015 Jul 15.

40.

Retroviral Integrase Structure and DNA Recombination Mechanism.

Engelman A, Cherepanov P.

Microbiol Spectr. 2014 Dec;2(6). doi: 10.1128/microbiolspec.MDNA3-0024-2014. Review.

PMID:
26104441
41.

Structural basis for retroviral integration into nucleosomes.

Maskell DP, Renault L, Serrao E, Lesbats P, Matadeen R, Hare S, Lindemann D, Engelman AN, Costa A, Cherepanov P.

Nature. 2015 Jul 16;523(7560):366-9. doi: 10.1038/nature14495. Epub 2015 Jun 10.

42.

Key determinants of target DNA recognition by retroviral intasomes.

Serrao E, Ballandras-Colas A, Cherepanov P, Maertens GN, Engelman AN.

Retrovirology. 2015 Apr 30;12:39. doi: 10.1186/s12977-015-0167-3.

43.

Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity.

Nuñez JK, Lee AS, Engelman A, Doudna JA.

Nature. 2015 Mar 12;519(7542):193-8. doi: 10.1038/nature14237. Epub 2015 Feb 18.

44.

Retroviral Integrase Structure and DNA Recombination Mechanism.

Engelman A, Cherepanov P.

Microbiol Spectr. 2014;2(6):1-22.

45.

Should we irradiate a brain tumor in a patient with parkinsonism? A case report and literature review.

Engelman A, Perumal K, Mehta M.

Pract Radiat Oncol. 2015 Jul-Aug;5(4):e327-35. doi: 10.1016/j.prro.2014.12.001. Epub 2015 Feb 4. Review.

PMID:
25659287
46.

The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.

Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M.

Retrovirology. 2014 Nov 25;11:100. doi: 10.1186/s12977-014-0100-1.

47.

Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses.

Wang H, Shun MC, Li X, Di Nunzio F, Hare S, Cherepanov P, Engelman A.

Mol Ther Methods Clin Dev. 2014 Jan 8;1. doi: 10.1038/mtm.2013.2.

48.

Host and viral determinants for MxB restriction of HIV-1 infection.

Matreyek KA, Wang W, Serrao E, Singh PK, Levin HL, Engelman A.

Retrovirology. 2014 Oct 25;11:90. doi: 10.1186/s12977-014-0090-z.

49.

Structural insight into HIV-1 restriction by MxB.

Fribourgh JL, Nguyen HC, Matreyek KA, Alvarez FJD, Summers BJ, Dewdney TG, Aiken C, Zhang P, Engelman A, Xiong Y.

Cell Host Microbe. 2014 Nov 12;16(5):627-638. doi: 10.1016/j.chom.2014.09.021. Epub 2014 Oct 9.

50.

The Rhode Island community responds to opioid overdose deaths.

Bowman S, Engelman A, Koziol J, Mahoney L, Maxwell C, McKenzie M.

R I Med J (2013). 2014 Oct 1;97(10):34-7.

PMID:
25271658

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