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Items: 1 to 50 of 642

1.

Derivation of induced pluripotent stem cells from ferret somatic cells.

Gao J, Petraki S, Sun X, Brooks LA, Lynch TJ, Hsieh CL, Elteriefi R, Lorenzana Z, Punj V, Engelhardt JF, Parekh KR, Ryan AL.

Am J Physiol Lung Cell Mol Physiol. 2020 Feb 19. doi: 10.1152/ajplung.00456.2019. [Epub ahead of print]

PMID:
32073882
2.

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.

Narayanan P, Curtis BR, Shen L, Schneider E, Tami JA, Paz S, Burel SA, Tai LJ, Machemer T, Kwoh TJ, Xia S, Shattil SJ, Witztum JL, Engelhardt JA, Henry SP, Monia BP, Hughes SG.

Nucleic Acid Ther. 2020 Feb 11. doi: 10.1089/nat.2019.0829. [Epub ahead of print]

PMID:
32043907
3.

A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.

Freeman ZT, Nirschl TR, Hovelson DH, Johnston RJ, Engelhardt JJ, Selby MJ, Kochel CM, Lan RY, Zhai J, Ghasemzadeh A, Gupta A, Skaist AM, Wheelan SJ, Jiang H, Pearson AT, Snyder LA, Korman AJ, Tomlins SA, Yegnasubramanian S, Drake CG.

J Clin Invest. 2020 Feb 4. pii: 128672. doi: 10.1172/JCI128672. [Epub ahead of print]

4.

Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).

Engelhardt J, Frisell O, Gustavsson H, Hansson T, Sjöberg R, Collier TK, Balk L.

PLoS One. 2020 Jan 2;15(1):e0227201. doi: 10.1371/journal.pone.0227201. eCollection 2020.

5.

In situ analysis reveals that CFTR is expressed in only a small minority of β-cells in normal adult human pancreas.

White MG, Maheshwari RR, Anderson SJ, Berlinguer-Palmini R, Jones C, Richardson SJ, Rotti PG, Armour SL, Ding Y, Krasnogor N, Engelhardt JF, Gray MA, Morgan NG, Shaw JAM.

J Clin Endocrinol Metab. 2019 Nov 21. pii: dgz209. doi: 10.1210/clinem/dgz209. [Epub ahead of print]

PMID:
31748811
6.

Improvement of a Radon Dosimetry System for Miners by Replacing Reference Dosimeters with Radonproof Boxes Containing Activated Carbon Cartridges.

Dehnert J, Guhr A, Engelhardt J.

Health Phys. 2020 Feb;118(2):117-128. doi: 10.1097/HP.0000000000001163.

PMID:
31688481
7.

Cellular Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Mediates Nuclear Import of Human Bocavirus 1 NP1 Protein and Modulates Viral Capsid Protein Expression.

Wang X, Xu P, Cheng F, Li Y, Wang Z, Hao S, Wang J, Ning K, Ganaie SS, Engelhardt JF, Yan Z, Qiu J.

J Virol. 2020 Jan 6;94(2). pii: e01444-19. doi: 10.1128/JVI.01444-19. Print 2020 Jan 6.

PMID:
31666379
8.

Increased Incidence of Intracranial Meningiomas in Patients With Acromegaly.

Engelhardt J, Nunes ML, Pouchieu C, Ferrière A, San-Galli F, Gimbert E, Vignes JR, Laurent F, Berge J, Baldi I, Tabarin A, Loiseau H.

Neurosurgery. 2019 Oct 18. pii: nyz438. doi: 10.1093/neuros/nyz438. [Epub ahead of print]

PMID:
31625569
9.

Comprehensive Genetic Analysis of a Hungarian Amyotrophic Lateral Sclerosis Cohort.

Tripolszki K, Gampawar P, Schmidt H, Nagy ZF, Nagy D, Klivényi P, Engelhardt JI, Széll M.

Front Genet. 2019 Aug 16;10:732. doi: 10.3389/fgene.2019.00732. eCollection 2019.

10.

Palladium Intercalated into the Walls of Mesoporous Silica as Robust and Regenerable Catalysts for Hydrodeoxygenation of Phenolic Compounds.

Gage SH, Engelhardt J, Menart MJ, Ngo C, Leong GJ, Ji Y, Trewyn BG, Pylypenko S, Richards RM.

ACS Omega. 2018 Jul 11;3(7):7681-7691. doi: 10.1021/acsomega.8b00951. eCollection 2018 Jul 31.

11.

Advances in gene therapy for cystic fibrosis lung disease.

Yan Z, McCray PB Jr, Engelhardt JF.

Hum Mol Genet. 2019 Oct 1;28(R1):R88-R94. doi: 10.1093/hmg/ddz139.

PMID:
31332440
12.

Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.

Aghajan M, Booten SL, Althage M, Hart CE, Ericsson A, Maxvall I, Ochaba J, Menschik-Lundin A, Hartleib J, Kuntz S, Gattis D, Ahlström C, Watt AT, Engelhardt JA, Monia BP, Magnone MC, Guo S.

JCI Insight. 2019 Jun 20;4(12). pii: 126124. doi: 10.1172/jci.insight.126124. eCollection 2019 Jun 20.

13.

Isolation of Redox-Active Endosomes (Redoxosomes) and Assessment of NOX Activity.

Shahin WS, Engelhardt JF.

Methods Mol Biol. 2019;1982:461-472. doi: 10.1007/978-1-4939-9424-3_27.

PMID:
31172489
14.

Experimental Motor Neuron Disease Induced in Mice with Long-Term Repeated Intraperitoneal Injections of Serum from ALS Patients.

Obál I, Nógrádi B, Meszlényi V, Patai R, Ricken G, Kovacs GG, Tripolszki K, Széll M, Siklós L, Engelhardt JI.

Int J Mol Sci. 2019 May 25;20(10). pii: E2573. doi: 10.3390/ijms20102573.

15.

Angiogenin mutations in Hungarian patients with amyotrophic lateral sclerosis: Clinical, genetic, computational, and functional analyses.

Tripolszki K, Danis J, Padhi AK, Gomes J, Bozó R, Nagy ZF, Nagy D, Klivényi P, Engelhardt JI, Széll M.

Brain Behav. 2019 Jun;9(6):e01293. doi: 10.1002/brb3.1293. Epub 2019 Apr 25.

16.

A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.

Fernandez-Petty CM, Hughes GW, Bowers HL, Watson JD, Rosen BH, Townsend SM, Santos C, Ridley CE, Chu KK, Birket SE, Li Y, Leung HM, Mazur M, Garcia BA, Evans TIA, Libby EF, Hathorne H, Hanes J, Tearney GJ, Clancy JP, Engelhardt JF, Swords WE, Thornton DJ, Wiesmann WP, Baker SM, Rowe SM.

JCI Insight. 2019 Apr 18;4(8). pii: 125954. doi: 10.1172/jci.insight.125954. eCollection 2019 Apr 18.

17.

In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.

Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF.

Sci Transl Med. 2019 Mar 27;11(485). pii: eaau7531. doi: 10.1126/scitranslmed.aau7531.

18.

Role of FcγRs in Antibody-Based Cancer Therapy.

Graziano RF, Engelhardt JJ.

Curr Top Microbiol Immunol. 2019;423:13-34. doi: 10.1007/82_2019_150. Review.

PMID:
30790079
19.

Highly Efficient Transgenesis in Ferrets Using CRISPR/Cas9-Mediated Homology-Independent Insertion at the ROSA26 Locus.

Yu M, Sun X, Tyler SR, Liang B, Swatek AM, Lynch TJ, He N, Yuan F, Feng Z, Rotti PG, Choi SH, Shahin W, Liu X, Yan Z, Engelhardt JF.

Sci Rep. 2019 Feb 13;9(1):1971. doi: 10.1038/s41598-018-37192-4.

20.

PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq.

Tyler SR, Rotti PG, Sun X, Yi Y, Xie W, Winter MC, Flamme-Wiese MJ, Tucker BA, Mullins RF, Norris AW, Engelhardt JF.

Cell Rep. 2019 Feb 12;26(7):1951-1964.e8. doi: 10.1016/j.celrep.2019.01.063.

21.

Survival in a bad neighborhood: pancreatic islets in cystic fibrosis.

Norris AW, Ode KL, Merjaneh L, Sanda S, Yi Y, Sun X, Engelhardt JF, Hull RL.

J Endocrinol. 2019 Feb 1. pii: JOE-18-0468.R1. doi: 10.1530/JOE-18-0468. [Epub ahead of print] Review.

PMID:
30759072
22.

Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin.

Sun X, Yi Y, Liang B, Yang Y, He N, Ode KL, Uc A, Wang K, Gibson-Corley KN, Engelhardt JF, Norris AW.

J Cyst Fibros. 2019 Jul;18(4):557-565. doi: 10.1016/j.jcf.2019.01.010. Epub 2019 Feb 7.

PMID:
30738804
23.

A Comprehensive RNA-seq Analysis of Human Bocavirus 1 Transcripts in Infected Human Airway Epithelium.

Zou W, Xiong M, Deng X, Engelhardt JF, Yan Z, Qiu J.

Viruses. 2019 Jan 7;11(1). pii: E33. doi: 10.3390/v11010033.

24.

Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1-Tg(HRAS)2Jic and CD-1 Mice.

Kim TW, Papagiannis CN, Zwick LS, Engelhardt JA, Hoffmaster CM, Post NM, Matson JE, Hsiao JA, Burel SA, Henry SP.

Toxicol Pathol. 2019 Jan;47(1):82-92. doi: 10.1177/0192623318813143. Epub 2018 Dec 25.

PMID:
30585133
25.

Localization of Deep Brain Stimulation Electrode by Image Registration Is Software Dependent: A Comparative Study between Four Widely Used Software Programs.

Engelhardt J, Guehl D, Damon-Perrière N, Branchard O, Burbaud P, Cuny E.

Stereotact Funct Neurosurg. 2018;96(6):364-369. doi: 10.1159/000494982. Epub 2018 Dec 19.

PMID:
30566953
26.

Establishment of a High-Yield Recombinant Adeno-Associated Virus/Human Bocavirus Vector Production System Independent of Bocavirus Nonstructural Proteins.

Yan Z, Zou W, Feng Z, Shen W, Park SY, Deng X, Qiu J, Engelhardt JF.

Hum Gene Ther. 2019 May;30(5):556-570. doi: 10.1089/hum.2018.173. Epub 2019 Jan 31.

PMID:
30398383
27.

Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes.

Wang Z, Cheng F, Engelhardt JF, Yan Z, Qiu J.

Mol Ther Methods Clin Dev. 2018 Oct 4;11:40-51. doi: 10.1016/j.omtm.2018.09.005. eCollection 2018 Dec 14.

28.

Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling.

Masch JM, Steffens H, Fischer J, Engelhardt J, Hubrich J, Keller-Findeisen J, D'Este E, Urban NT, Grant SGN, Sahl SJ, Kamin D, Hell SW.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8047-E8056. doi: 10.1073/pnas.1807104115. Epub 2018 Aug 6.

29.

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J.

Nature. 2018 Aug;560(7718):319-324. doi: 10.1038/s41586-018-0393-7. Epub 2018 Aug 1.

30.

[Calcium ion is a common denominator in the pathophysiological processes of amyotrophic lateral sclerosis].

Patai R, Nógrádi B, Meszlényi V, Obál I, Engelhardt J, Siklós L.

Ideggyogy Sz. 2017 Jul 30;70(7-8):247-257. doi: 10.18071/isz.70.0247. Review. Hungarian.

PMID:
29870639
31.

Contralateral Transcranial Approach to Tuberculum Sellae Meningiomas: Long-Term Visual Outcomes and Recurrence Rates.

Engelhardt J, Namaki H, Mollier O, Monteil P, Penchet G, Cuny E, Loiseau H.

World Neurosurg. 2018 Aug;116:e1066-e1074. doi: 10.1016/j.wneu.2018.05.166. Epub 2018 Jun 1.

PMID:
29864568
32.

The rs13388259 Intergenic Polymorphism in the Genomic Context of the BCYRN1 Gene Is Associated with Parkinson's Disease in the Hungarian Population.

Márki S, Göblös A, Szlávicz E, Török N, Balicza P, Bereznai B, Takáts A, Engelhardt J, Klivényi P, Vécsei L, Molnár MJ, Nagy N, Széll M.

Parkinsons Dis. 2018 Apr 3;2018:9351598. doi: 10.1155/2018/9351598. eCollection 2018.

33.

Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2'-MOE-Modified Antisense Oligonucleotide.

Narayanan P, Shen L, Curtis BR, Bourdon MA, Nolan JP, Gupta S, Hoffmaster C, Zhou F, Christian B, Schaubhut JL, Greenlee S, Burel SA, Witztum JL, Engelhardt JA, Henry SP.

Toxicol Sci. 2018 Aug 1;164(2):613-626. doi: 10.1093/toxsci/kfy119.

PMID:
29846725
34.

Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF.

Cell Stem Cell. 2018 May 3;22(5):779. doi: 10.1016/j.stem.2018.04.007. No abstract available.

35.

Validation of a radioimmunoassay of serum trypsin-like immunoreactivity in ferrets.

Bridges CS, Miller PS, Lidbury JA, Suchodolski JS, Yi Y, Engelhardt JF, Steiner JM.

J Vet Diagn Invest. 2018 Jul;30(4):517-522. doi: 10.1177/1040638718774387. Epub 2018 May 2.

36.

Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF.

Cell Stem Cell. 2018 May 3;22(5):653-667.e5. doi: 10.1016/j.stem.2018.03.017. Epub 2018 Apr 12. Erratum in: Cell Stem Cell. 2018 May 3;22(5):779.

37.

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size.

Johnson MB, Sun X, Kodani A, Borges-Monroy R, Girskis KM, Ryu SC, Wang PP, Patel K, Gonzalez DM, Woo YM, Yan Z, Liang B, Smith RS, Chatterjee M, Coman D, Papademetris X, Staib LH, Hyder F, Mandeville JB, Grant PE, Im K, Kwak H, Engelhardt JF, Walsh CA, Bae BI.

Nature. 2018 Apr;556(7701):370-375. doi: 10.1038/s41586-018-0035-0. Epub 2018 Apr 11.

38.

Development of a polarized pancreatic ductular cell epithelium for physiological studies.

O'Malley Y, Rotti PG, Thornell IM, Vanegas Calderón OG, Febres-Aldana C, Durham K, Yao J, Li X, Zhu Z, Norris AW, Zabner J, Engelhardt JF, Uc A.

J Appl Physiol (1985). 2018 Jul 1;125(1):97-106. doi: 10.1152/japplphysiol.00043.2018. Epub 2018 Mar 8.

39.

Characterizing Adversity of Lysosomal Accumulation in Nonclinical Toxicity Studies: Results from the 5th ESTP International Expert Workshop.

Lenz B, Braendli-Baiocco A, Engelhardt J, Fant P, Fischer H, Francke S, Fukuda R, Gröters S, Harada T, Harleman H, Kaufmann W, Kustermann S, Nolte T, Palazzi X, Pohlmeyer-Esch G, Popp A, Romeike A, Schulte A, Lima BS, Tomlinson L, Willard J, Wood CE, Yoshida M.

Toxicol Pathol. 2018 Feb;46(2):224-246. doi: 10.1177/0192623317749452.

PMID:
29471779
40.

STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.

Vlijm R, Li X, Panic M, Rüthnick D, Hata S, Herrmannsdörfer F, Kuner T, Heilemann M, Engelhardt J, Hell SW, Schiebel E.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2246-E2253. doi: 10.1073/pnas.1716840115. Epub 2018 Feb 20.

41.

Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.

Rotti PG, Xie W, Poudel A, Yi Y, Sun X, Tyler SR, Uc A, Norris AW, Hara M, Engelhardt JF, Gibson-Corley KN.

Am J Pathol. 2018 Apr;188(4):876-890. doi: 10.1016/j.ajpath.2017.12.015. Epub 2018 Jan 31.

42.

Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets.

Rosen BH, Evans TIA, Moll SR, Gray JS, Liang B, Sun X, Zhang Y, Jensen-Cody CW, Swatek AM, Zhou W, He N, Rotti PG, Tyler SR, Keiser NW, Anderson PJ, Brooks L, Li Y, Pope RM, Rajput M, Hoffman EA, Wang K, Harris JK, Parekh KR, Gibson-Corley KN, Engelhardt JF.

Am J Respir Crit Care Med. 2018 May 15;197(10):1308-1318. doi: 10.1164/rccm.201708-1616OC.

43.

Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis.

Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1045-1057. doi: 10.1164/rccm.201707-1368OC.

45.

Ecological plant epigenetics: Evidence from model and non-model species, and the way forward.

Richards CL, Alonso C, Becker C, Bossdorf O, Bucher E, Colomé-Tatché M, Durka W, Engelhardt J, Gaspar B, Gogol-Döring A, Grosse I, van Gurp TP, Heer K, Kronholm I, Lampei C, Latzel V, Mirouze M, Opgenoorth L, Paun O, Prohaska SJ, Rensing SA, Stadler PF, Trucchi E, Ullrich K, Verhoeven KJF.

Ecol Lett. 2017 Dec;20(12):1576-1590. doi: 10.1111/ele.12858. Epub 2017 Oct 12. Review.

PMID:
29027325
46.

Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis.

Deng X, Zou W, Xiong M, Wang Z, Engelhardt JF, Ye SQ, Yan Z, Qiu J.

J Virol. 2017 Nov 30;91(24). pii: e01533-17. doi: 10.1128/JVI.01533-17. Print 2017 Dec 15.

47.

CFTR Influences Beta Cell Function and Insulin Secretion Through Non-Cell Autonomous Exocrine-Derived Factors.

Sun X, Yi Y, Xie W, Liang B, Winter MC, He N, Liu X, Luo M, Yang Y, Ode KL, Uc A, Norris AW, Engelhardt JF.

Endocrinology. 2017 Oct 1;158(10):3325-3338. doi: 10.1210/en.2017-00187.

48.

Animal and model systems for studying cystic fibrosis.

Rosen BH, Chanson M, Gawenis LR, Liu J, Sofoluwe A, Zoso A, Engelhardt JF.

J Cyst Fibros. 2018 Mar;17(2S):S28-S34. doi: 10.1016/j.jcf.2017.09.001. Epub 2017 Sep 19. Review.

49.

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.

Akay A, Di Domenico T, Suen KM, Nabih A, Parada GE, Larance M, Medhi R, Berkyurek AC, Zhang X, Wedeles CJ, Rudolph KLM, Engelhardt J, Hemberg M, Ma P, Lamond AI, Claycomb JM, Miska EA.

Dev Cell. 2017 Aug 7;42(3):241-255.e6. doi: 10.1016/j.devcel.2017.07.002.

50.

Real-Time Monitoring of Insulin Using a Graphene Field-Effect Transistor Aptameric Nanosensor.

Hao Z, Zhu Y, Wang X, Rotti PG, DiMarco C, Tyler SR, Zhao X, Engelhardt JF, Hone J, Lin Q.

ACS Appl Mater Interfaces. 2017 Aug 23;9(33):27504-27511. doi: 10.1021/acsami.7b07684. Epub 2017 Aug 11.

PMID:
28770993

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