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Items: 1 to 50 of 359

1.

Connectivity of centermost chromatophores in Rhodobacter sphaeroides bacteria.

Noble JM, Lubieniecki J, Savitzky BH, Plitzko J, Engelhardt H, Baumeister W, Kourkoutis LF.

Mol Microbiol. 2018 Sep;109(6):812-825. doi: 10.1111/mmi.14077. Epub 2018 Sep 15.

PMID:
29995992
2.

The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML.

Gerlach D, Tontsch-Grunt U, Baum A, Popow J, Scharn D, Hofmann MH, Engelhardt H, Kaya O, Beck J, Schweifer N, Gerstberger T, Zuber J, Savarese F, Kraut N.

Oncogene. 2018 May;37(20):2687-2701. doi: 10.1038/s41388-018-0150-2. Epub 2018 Mar 1.

3.

Synergistic activity of BET inhibitor BI 894999 with PLK inhibitor volasertib in AML in vitro and in vivo.

Tontsch-Grunt U, Rudolph D, Waizenegger I, Baum A, Gerlach D, Engelhardt H, Wurm M, Savarese F, Schweifer N, Kraut N.

Cancer Lett. 2018 May 1;421:112-120. doi: 10.1016/j.canlet.2018.02.018. Epub 2018 Feb 14.

4.

Structural studies of Acidianus tailed spindle virus reveal a structural paradigm used in the assembly of spindle-shaped viruses.

Hochstein R, Bollschweiler D, Dharmavaram S, Lintner NG, Plitzko JM, Bruinsma R, Engelhardt H, Young MJ, Klug WS, Lawrence CM.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2120-2125. doi: 10.1073/pnas.1719180115. Epub 2018 Feb 12.

5.

Alternating-magnetic-field induced enhancement of diffusivity in Ni-Cr alloys.

Li C, He S, Engelhardt H, Zhan T, Xuan W, Li X, Zhong Y, Ren Z, Rettenmayr M.

Sci Rep. 2017 Dec 22;7(1):18085. doi: 10.1038/s41598-017-18500-w.

6.

Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design.

Geist L, Mayer M, Cockcroft XL, Wolkerstorfer B, Kessler D, Engelhardt H, McConnell DB, Konrat R.

J Med Chem. 2017 Nov 9;60(21):8708-8715. doi: 10.1021/acs.jmedchem.7b00845. Epub 2017 Oct 1.

PMID:
28910100
7.

Basic Colorimetric Proliferation Assays: MTT, WST, and Resazurin.

Präbst K, Engelhardt H, Ringgeler S, Hübner H.

Methods Mol Biol. 2017;1601:1-17. doi: 10.1007/978-1-4939-6960-9_1.

PMID:
28470513
8.

Determining the bacterial cell biology of Planctomycetes.

Boedeker C, Schüler M, Reintjes G, Jeske O, van Teeseling MC, Jogler M, Rast P, Borchert D, Devos DP, Kucklick M, Schaffer M, Kolter R, van Niftrik L, Engelmann S, Amann R, Rohde M, Engelhardt H, Jogler C.

Nat Commun. 2017 Apr 10;8:14853. doi: 10.1038/ncomms14853. Review.

9.

Cryo-electron microscopy of an extremely halophilic microbe: technical aspects.

Bollschweiler D, Schaffer M, Lawrence CM, Engelhardt H.

Extremophiles. 2017 Mar;21(2):393-398. doi: 10.1007/s00792-016-0912-0. Epub 2017 Jan 3.

10.

Bowel preparation in pediatric colonoscopy: results of an open observational study.

Berger T, Classen M, Engelhardt H, Keller KM, Laass MW, Melchior R, Posovszky C, Rodeck B, Schaper K, Behrens R.

Endosc Int Open. 2016 Jul;4(7):E820-7. doi: 10.1055/s-0042-107789. Epub 2016 Jun 2.

11.

No correlation between rates of suicidal ideation and completed suicides in Europe: analysis of 49,008 participants (55+ years) based on the Survey of Health, Ageing and Retirement in Europe (SHARE).

Lukaschek K, Engelhardt H, Baumert J, Ladwig KH.

Eur Psychiatry. 2015 Oct;30(7):874-9. doi: 10.1016/j.eurpsy.2015.07.009. Epub 2015 Sep 25.

PMID:
26443056
12.

[Considerations and recommondations for species-appropriate and welfare friendly keeping of ratitae in Germany].

Korbel R, Schubert M, Erhard M, Wöhr C, Bergmann S, Rückschloss S, Thiel S, Engelhardt H, Engelhardt S.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2015;43(4):232-44. doi: 10.15653/TPG-150490. Epub 2015 Aug 3. German.

PMID:
26235357
13.

Large Tailed Spindle Viruses of Archaea: a New Way of Doing Viral Business.

Hochstein R, Bollschweiler D, Engelhardt H, Lawrence CM, Young M.

J Virol. 2015 Sep;89(18):9146-9. doi: 10.1128/JVI.00612-15. Epub 2015 Jun 17. Review.

14.

Fertility and social interaction at the workplace: Does childbearing spread among colleagues?

Pink S, Leopold T, Engelhardt H.

Adv Life Course Res. 2014 Sep;21:113-22. doi: 10.1016/j.alcr.2013.12.001. Epub 2013 Dec 19.

PMID:
26047546
15.

Planctomycetes do possess a peptidoglycan cell wall.

Jeske O, Schüler M, Schumann P, Schneider A, Boedeker C, Jogler M, Bollschweiler D, Rohde M, Mayer C, Engelhardt H, Spring S, Jogler C.

Nat Commun. 2015 May 12;6:7116. doi: 10.1038/ncomms8116.

16.

Courage: facing and living with moral diversity.

Engelhardt HT Jr.

J Med Philos. 2015 Jun;40(3):278-80. doi: 10.1093/jmp/jhv003. Epub 2015 Apr 18. No abstract available.

PMID:
25889263
17.

The bactofilin cytoskeleton protein BacM of Myxococcus xanthus forms an extended β-sheet structure likely mediated by hydrophobic interactions.

Zuckerman DM, Boucher LE, Xie K, Engelhardt H, Bosch J, Hoiczyk E.

PLoS One. 2015 Mar 24;10(3):e0121074. doi: 10.1371/journal.pone.0121074. eCollection 2015.

18.

A two years longitudinal study of a transgenic Huntington disease monkey.

Chan AW, Xu Y, Jiang J, Rahim T, Zhao D, Kocerha J, Chi T, Moran S, Engelhardt H, Larkin K, Neumann A, Cheng H, Li C, Nelson K, Banta H, Zola SM, Villinger F, Yang J, Testa CM, Mao H, Zhang X, Bachevalier J.

BMC Neurosci. 2014 Mar 3;15:36. doi: 10.1186/1471-2202-15-36.

19.

Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys.

Kocerha J, Liu Y, Willoughby D, Chidamparam K, Benito J, Nelson K, Xu Y, Chi T, Engelhardt H, Moran S, Yang SH, Li SH, Li XJ, Larkin K, Neumann A, Banta H, Yang JJ, Chan AW.

BMC Neurosci. 2013 Aug 17;14:88. doi: 10.1186/1471-2202-14-88.

20.

Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode.

Engelhardt H, Schultes S, de Graaf C, Nijmeijer S, Vischer HF, Zuiderveld OP, Dobler J, Stachurski K, Mayer M, Arnhof H, Scharn D, Haaksma EE, de Esch IJ, Leurs R.

J Med Chem. 2013 Jun 13;56(11):4264-76. doi: 10.1021/jm301886t. Epub 2013 May 28.

PMID:
23668417
21.

Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues.

Nijmeijer S, Vischer HF, Sirci F, Schultes S, Engelhardt H, de Graaf C, Rosethorne EM, Charlton SJ, Leurs R.

Br J Pharmacol. 2013 Sep;170(1):78-88. doi: 10.1111/bph.12117.

22.

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.

Nijmeijer S, Engelhardt H, Schultes S, van de Stolpe AC, Lusink V, de Graaf C, Wijtmans M, Haaksma EE, de Esch IJ, Stachurski K, Vischer HF, Leurs R.

Br J Pharmacol. 2013 Sep;170(1):89-100. doi: 10.1111/bph.12113.

23.

Visualizing the bacterial cell surface: an overview.

Engelhardt H.

Methods Mol Biol. 2013;966:15-35. doi: 10.1007/978-1-62703-245-2_2. Review.

PMID:
23299726
24.

Fair equality of opportunity critically reexamined: the family and the sustainability of health care systems.

Engelhardt HT Jr.

J Med Philos. 2012 Dec;37(6):583-602. doi: 10.1093/jmp/jhs044. Epub 2012 Nov 30.

PMID:
23204308
25.

Combining quantum mechanical ligand conformation analysis and protein modeling to elucidate GPCR-ligand binding modes.

Schultes S, Engelhardt H, Roumen L, Zuiderveld OP, Haaksma EE, de Esch IJ, Leurs R, de Graaf C.

ChemMedChem. 2013 Jan;8(1):49-53. doi: 10.1002/cmdc.201200412. Epub 2012 Nov 19.

PMID:
23161844
26.

Unraveling the structure of membrane proteins in situ by transfer function corrected cryo-electron tomography.

Eibauer M, Hoffmann C, Plitzko JM, Baumeister W, Nickell S, Engelhardt H.

J Struct Biol. 2012 Dec;180(3):488-96. doi: 10.1016/j.jsb.2012.09.008. Epub 2012 Sep 18.

PMID:
23000705
27.

Education and physical health trajectories in old age. Evidence from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Leopold L, Engelhardt H.

Int J Public Health. 2013 Feb;58(1):23-31. doi: 10.1007/s00038-012-0399-0. Epub 2012 Aug 24. Erratum in: Int J Public Health. 2013 Apr;58(2):329. Engelhartdt, Henriette [corrected to Engelhardt, Henriette].

PMID:
22918517
28.

Detailed structure-activity relationship of indolecarboxamides as H4 receptor ligands.

Engelhardt H, de Esch IJ, Kuhn D, Smits RA, Zuiderveld OP, Dobler J, Mayer M, Lips S, Arnhof H, Scharn D, Haaksma EE, Leurs R.

Eur J Med Chem. 2012 Aug;54:660-8. doi: 10.1016/j.ejmech.2012.06.016. Epub 2012 Jun 18.

PMID:
22749391
29.

Bioethics critically reconsidered: living after foundations.

Engelhardt HT Jr.

Theor Med Bioeth. 2012 Feb;33(1):97-105. doi: 10.1007/s11017-011-9204-y.

PMID:
22270710
30.

Evaluating the potential of effluents and wood feedstocks from pulp and paper mills in Brazil, Canada, and New Zealand to affect fish reproduction: chemical profiling and in vitro assessments.

Milestone CB, Orrego R, Scott PD, Waye A, Kohli J, O'Connor BI, Smith B, Engelhardt H, Servos MR, Maclatchy DL, Smith DS, Trudeau VL, Arnason JT, Kovacs T, Heid Furley T, Slade AH, Holdway DA, Hewitt LM.

Environ Sci Technol. 2012 Feb 7;46(3):1849-58. doi: 10.1021/es203382c. Epub 2012 Jan 26.

PMID:
22196476
31.

Core competencies for health care ethics consultants: in search of professional status in a post-modern world.

Engelhardt HT Jr.

HEC Forum. 2011 Sep;23(3):129-45. doi: 10.1007/s10730-011-9167-4.

PMID:
21909689
32.

Confronting moral pluralism in posttraditional Western societies: bioethics critically reassessed.

Engelhardt HT Jr.

J Med Philos. 2011 Jun;36(3):243-60. doi: 10.1093/jmp/jhr011. Epub 2011 Jul 1.

PMID:
21724971
33.

Structural model of the gas vesicle protein GvpA and analysis of GvpA mutants in vivo.

Strunk T, Hamacher K, Hoffgaard F, Engelhardt H, Zillig MD, Faist K, Wenzel W, Pfeifer F.

Mol Microbiol. 2011 Jul;81(1):56-68. doi: 10.1111/j.1365-2958.2011.07669.x. Epub 2011 May 27.

34.

Extracellular Streptomyces vesicles: amphorae for survival and defence.

Schrempf H, Koebsch I, Walter S, Engelhardt H, Meschke H.

Microb Biotechnol. 2011 Mar;4(2):286-99. doi: 10.1111/j.1751-7915.2011.00251.x.

35.

Reliability of myocardial salvage assessment by cardiac magnetic resonance imaging in acute reperfused myocardial infarction.

Desch S, Engelhardt H, Meissner J, Eitel I, Sareban M, Fuernau G, de Waha S, Grothoff M, Gutberlet M, Schuler G, Thiele H.

Int J Cardiovasc Imaging. 2012 Feb;28(2):263-72. doi: 10.1007/s10554-011-9802-9. Epub 2011 Jan 30.

PMID:
21279689
36.

[Successful treatment of secondary aortoesophageal fistula after thoracic endovascular aortic repair].

Engelhardt H, Paul A, Niebel W, Dechêne A, Przyborek M, Tsagakis K, Kühl H, Jakob H, Erbel R, Eggebrecht H.

Dtsch Med Wochenschr. 2010 Oct;135(42):2076-80. doi: 10.1055/s-0030-1267486. Epub 2010 Oct 12. German.

PMID:
20941681
37.

Beyond the best interests of children: four views of the family and of foundational disagreements regarding pediatric decision making.

Engelhardt HT Jr.

J Med Philos. 2010 Oct;35(5):499-517. doi: 10.1093/jmp/jhq042. Epub 2010 Oct 5. Review.

PMID:
20923929
38.

Monkey steering responses reveal rapid visual-motor feedback.

Egger SW, Engelhardt HR, Britten KH.

PLoS One. 2010 Aug 4;5(8):e11975. doi: 10.1371/journal.pone.0011975.

39.

Mycobacterial outer membranes: in search of proteins.

Niederweis M, Danilchanka O, Huff J, Hoffmann C, Engelhardt H.

Trends Microbiol. 2010 Mar;18(3):109-16. doi: 10.1016/j.tim.2009.12.005. Epub 2010 Jan 8. Review.

40.

A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinic.

Engelhardt H, Smits RA, Leurs R, Haaksma E, de Esch IJ.

Curr Opin Drug Discov Devel. 2009 Sep;12(5):628-43. Review.

PMID:
19736622
41.

Credentialing strategically ambiguous and heterogeneous social skills: the emperor without clothes.

Engelhardt HT Jr.

HEC Forum. 2009 Sep;21(3):293-306. doi: 10.1007/s10730-009-9106-9. No abstract available.

PMID:
19705284
42.

The influence of offspring's sex and age at parents' divorce on the intergenerational transmission of divorce, Norwegian first marriages 1980-2003.

Lyngstad TH, Engelhardt H.

Popul Stud (Camb). 2009 Jul;63(2):173-85. doi: 10.1080/00324720902896044.

PMID:
19536699
43.

Bacteria beneath the West Antarctic ice sheet.

Lanoil B, Skidmore M, Priscu JC, Han S, Foo W, Vogel SW, Tulaczyk S, Engelhardt H.

Environ Microbiol. 2009 Mar;11(3):609-15. doi: 10.1111/j.1462-2920.2008.01831.x.

PMID:
19278447
44.

[Performance of self-help groups and their economic evaluation].

Engelhardt HD, Trojan A, Nickel S.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 Jan;52(1):64-70. doi: 10.1007/s00103-009-0749-0. Review. German.

PMID:
19189156
45.

[The economic benefits of self-help associations].

Trojan A, Nickel S, Engelhardt HD.

Gesundheitswesen. 2008 Apr;70(4):219-30. doi: 10.1055/s-2008-1065359. German.

PMID:
18512196
46.

Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure.

Hoffmann C, Leis A, Niederweis M, Plitzko JM, Engelhardt H.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3963-7. doi: 10.1073/pnas.0709530105. Epub 2008 Mar 3.

47.

Children's impact on the mental health of their older mothers and fathers: findings from the Survey of Health, Ageing and Retirement in Europe.

Buber I, Engelhardt H.

Eur J Ageing. 2008 Feb 13;5(1):31-45. doi: 10.1007/s10433-008-0074-8. eCollection 2008 Mar.

48.

Long-term care: the family, post-modernity, and conflicting moral life-worlds.

Engelhardt HT Jr.

J Med Philos. 2007 Sep-Oct;32(5):519-36.

PMID:
17924275
49.

Are S-layers exoskeletons? The basic function of protein surface layers revisited.

Engelhardt H.

J Struct Biol. 2007 Nov;160(2):115-24. Epub 2007 Aug 11. Review.

PMID:
17889557
50.

Mechanism of osmoprotection by archaeal S-layers: a theoretical study.

Engelhardt H.

J Struct Biol. 2007 Nov;160(2):190-9. Epub 2007 Aug 11.

PMID:
17888677

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