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Items: 15

1.

A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology.

Gerez JA, Prymaczok NC, Rockenstein E, Herrmann US, Schwarz P, Adame A, Enchev RI, Courtheoux T, Boersema PJ, Riek R, Peter M, Aguzzi A, Masliah E, Picotti P.

Sci Transl Med. 2019 Jun 5;11(495). pii: eaau6722. doi: 10.1126/scitranslmed.aau6722.

PMID:
31167929
2.

Regulatory control of DNA end resection by Sae2 phosphorylation.

Cannavo E, Johnson D, Andres SN, Kissling VM, Reinert JK, Garcia V, Erie DA, Hess D, Thomä NH, Enchev RI, Peter M, Williams RS, Neale MJ, Cejka P.

Nat Commun. 2018 Oct 1;9(1):4016. doi: 10.1038/s41467-018-06417-5.

3.

Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.

Janouskova H, El Tekle G, Bellini E, Udeshi ND, Rinaldi A, Ulbricht A, Bernasocchi T, Civenni G, Losa M, Svinkina T, Bielski CM, Kryukov GV, Cascione L, Napoli S, Enchev RI, Mutch DG, Carney ME, Berchuck A, Winterhoff BJN, Broaddus RR, Schraml P, Moch H, Bertoni F, Catapano CV, Peter M, Carr SA, Garraway LA, Wild PJ, Theurillat JP.

Nat Med. 2017 Sep;23(9):1046-1054. doi: 10.1038/nm.4372. Epub 2017 Aug 14.

4.

Corrigendum: Cortical dynamics during cell motility are regulated by CRL3KLHL21 E3 ubiquitin ligase.

Courtheoux T, Enchev RI, Lampert F, Gerez J, Beck J, Picotti P, Sumara I, Peter M.

Nat Commun. 2016 Oct 31;7:13487. doi: 10.1038/ncomms13487. No abstract available.

5.

Cortical dynamics during cell motility are regulated by CRL3(KLHL21) E3 ubiquitin ligase.

Courtheoux T, Enchev RI, Lampert F, Gerez J, Beck J, Picotti P, Sumara I, Peter M.

Nat Commun. 2016 Sep 19;7:12810. doi: 10.1038/ncomms12810. Erratum in: Nat Commun. 2016 Oct 31;7:13487.

6.

Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection.

Ferretti LP, Himmels SF, Trenner A, Walker C, von Aesch C, Eggenschwiler A, Murina O, Enchev RI, Peter M, Freire R, Porro A, Sartori AA.

Nat Commun. 2016 Aug 26;7:12628. doi: 10.1038/ncomms12628.

7.

Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle.

Mosadeghi R, Reichermeier KM, Winkler M, Schreiber A, Reitsma JM, Zhang Y, Stengel F, Cao J, Kim M, Sweredoski MJ, Hess S, Leitner A, Aebersold R, Peter M, Deshaies RJ, Enchev RI.

Elife. 2016 Mar 31;5. pii: e12102. doi: 10.7554/eLife.12102.

8.

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes.

Gschweitl M, Ulbricht A, Barnes CA, Enchev RI, Stoffel-Studer I, Meyer-Schaller N, Huotari J, Yamauchi Y, Greber UF, Helenius A, Peter M.

Elife. 2016 Mar 23;5:e13841. doi: 10.7554/eLife.13841.

9.

A mechanism for the suppression of homologous recombination in G1 cells.

Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M, Durocher D.

Nature. 2015 Dec 17;528(7582):422-6. doi: 10.1038/nature16142. Epub 2015 Dec 9.

10.

Protein neddylation: beyond cullin-RING ligases.

Enchev RI, Schulman BA, Peter M.

Nat Rev Mol Cell Biol. 2015 Jan;16(1):30-44. doi: 10.1038/nrm3919. Review.

11.

Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer.

Birol M, Enchev RI, Padilla A, Stengel F, Aebersold R, Betzi S, Yang Y, Hoh F, Peter M, Dumas C, Echalier A.

PLoS One. 2014 Aug 21;9(8):e105688. doi: 10.1371/journal.pone.0105688. eCollection 2014.

12.

Structural basis for a reciprocal regulation between SCF and CSN.

Enchev RI, Scott DC, da Fonseca PC, Schreiber A, Monda JK, Schulman BA, Peter M, Morris EP.

Cell Rep. 2012 Sep 27;2(3):616-27. doi: 10.1016/j.celrep.2012.08.019. Epub 2012 Sep 6.

13.

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21.

Ye Y, Akutsu M, Reyes-Turcu F, Enchev RI, Wilkinson KD, Komander D.

EMBO Rep. 2011 Apr;12(4):350-7. doi: 10.1038/embor.2011.17. Epub 2011 Mar 11.

14.

Structural basis for the subunit assembly of the anaphase-promoting complex.

Schreiber A, Stengel F, Zhang Z, Enchev RI, Kong EH, Morris EP, Robinson CV, da Fonseca PC, Barford D.

Nature. 2011 Feb 10;470(7333):227-32. doi: 10.1038/nature09756.

PMID:
21307936
15.

Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.

Enchev RI, Schreiber A, Beuron F, Morris EP.

Structure. 2010 Mar 14;18(4):518-27. doi: 10.1016/j.str.2010.02.008.

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