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Items: 1 to 50 of 87

1.

Triggering nucleic acid nanostructure assembly by conditional kissing interactions.

Azéma L, Bonnet-Salomon S, Endo M, Takeuchi Y, Durand G, Emura T, Hidaka K, Dausse E, Sugiyama H, Toulmé JJ.

Nucleic Acids Res. 2018 Feb 16;46(3):1052-1058. doi: 10.1093/nar/gkx1267.

2.

Single-Molecule Observation of the Photoregulated Conformational Dynamics of DNA Origami Nanoscissors.

Willner EM, Kamada Y, Suzuki Y, Emura T, Hidaka K, Dietz H, Sugiyama H, Endo M.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15324-15328. doi: 10.1002/anie.201708722. Epub 2017 Oct 30.

PMID:
29044955
3.

Confined space facilitates G-quadruplex formation.

Shrestha P, Jonchhe S, Emura T, Hidaka K, Endo M, Sugiyama H, Mao H.

Nat Nanotechnol. 2017 Jul;12(6):582-588. doi: 10.1038/nnano.2017.29. Epub 2017 Mar 27.

PMID:
28346457
4.

A Photoregulated DNA-Based Rotary System and Direct Observation of Its Rotational Movement.

Yang Y, Tashiro R, Suzuki Y, Emura T, Hidaka K, Sugiyama H, Endo M.

Chemistry. 2017 Mar 17;23(16):3979-3985. doi: 10.1002/chem.201605616. Epub 2017 Feb 15.

PMID:
28199775
5.

Personalized dynamic prediction of death according to tumour progression and high-dimensional genetic factors: Meta-analysis with a joint model.

Emura T, Nakatochi M, Matsui S, Michimae H, Rondeau V.

Stat Methods Med Res. 2018 Sep;27(9):2842-2858. doi: 10.1177/0962280216688032. Epub 2017 Jan 16.

PMID:
28090814
6.

Dieulafoy lesion in a two-year-old boy: a case report.

Emura T, Hosoda K, Harai S, Oyachi N, Suzuki T, Takada K, Kobayashi K, Ikeda H.

J Med Case Rep. 2016 Oct 19;10(1):293.

7.

A Modified Technique with a New Device of Laparoscopic Percutaneous Extraperitoneal Closure for Pediatric Inguinal Hernia.

Emura T, Ohta H, Oyachi N, Suzuki T.

J Laparoendosc Adv Surg Tech A. 2016 Dec;26(12):1028-1031. Epub 2016 Sep 28.

PMID:
27680331
8.

Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores.

Shrestha P, Emura T, Koirala D, Cui Y, Hidaka K, Maximuck WJ, Endo M, Sugiyama H, Mao H.

Nucleic Acids Res. 2016 Aug 19;44(14):6574-82. doi: 10.1093/nar/gkw610. Epub 2016 Jul 7.

9.

Triple Helix Formation in a Topologically Controlled DNA Nanosystem.

Yamagata Y, Emura T, Hidaka K, Sugiyama H, Endo M.

Chemistry. 2016 Apr 11;22(16):5494-8. doi: 10.1002/chem.201505030. Epub 2016 Mar 3.

PMID:
26938310
10.

Development of a Scalable Synthesis of Tofogliflozin.

Ohtake Y, Emura T, Nishimoto M, Takano K, Yamamoto K, Tsuchiya S, Yeu SY, Kito Y, Kimura N, Takeda S, Tsukazaki M, Murakata M, Sato T.

J Org Chem. 2016 Mar 4;81(5):2148-53. doi: 10.1021/acs.joc.5b02734. Epub 2016 Feb 19.

PMID:
26871504
11.

A joint frailty-copula model between tumour progression and death for meta-analysis.

Emura T, Nakatochi M, Murotani K, Rondeau V.

Stat Methods Med Res. 2017 Dec;26(6):2649-2666. doi: 10.1177/0962280215604510. Epub 2015 Sep 18.

PMID:
26384516
12.

Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure.

Endo M, Xing X, Zhou X, Emura T, Hidaka K, Tuesuwan B, Sugiyama H.

ACS Nano. 2015 Oct 27;9(10):9922-9. doi: 10.1021/acsnano.5b03413. Epub 2015 Sep 24.

PMID:
26371377
13.

Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells.

Nishida Y, Ohtsuki S, Araie Y, Umeki Y, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M.

Nanomedicine. 2016 Jan;12(1):123-30. doi: 10.1016/j.nano.2015.08.004. Epub 2015 Sep 11.

PMID:
26364795
14.

Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells.

Ohtsuki S, Matsuzaki N, Mohri K, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Ishiyama K, Kadowaki N, Takakura Y, Nishikawa M.

Nucleic Acid Ther. 2015 Oct;25(5):245-53. doi: 10.1089/nat.2014.0524. Epub 2015 Jul 29.

PMID:
26222130
15.

Single-Molecule Visualization of the Activity of a Zn(2+)-Dependent DNAzyme.

Endo M, Takeuchi Y, Suzuki Y, Emura T, Hidaka K, Wang F, Willner I, Sugiyama H.

Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10550-4. doi: 10.1002/anie.201504656. Epub 2015 Jul 17.

PMID:
26195344
16.

Linking two DNA duplexes with a rigid linker for DNA nanotechnology.

Tashiro R, Iwamoto M, Morinaga H, Emura T, Hidaka K, Endo M, Sugiyama H.

Nucleic Acids Res. 2015 Aug 18;43(14):6692-700. doi: 10.1093/nar/gkv662. Epub 2015 Jun 30.

17.

CH5137291, an androgen receptor nuclear translocation-inhibiting compound, inhibits the growth of castration-resistant prostate cancer cells.

Ishikura N, Kawata H, Nishimoto A, Nakamura R, Tsunenari T, Watanabe M, Tachibana K, Shiraishi T, Yoshino H, Honma A, Emura T, Ohta M, Nakagawa T, Houjo T, Corey E, Vessella RL, Aoki Y, Sato H.

Int J Oncol. 2015 Apr;46(4):1560-72. doi: 10.3892/ijo.2015.2860. Epub 2015 Jan 30.

PMID:
25634071
18.

Preparation of chemically modified RNA origami nanostructures.

Endo M, Takeuchi Y, Emura T, Hidaka K, Sugiyama H.

Chemistry. 2014 Nov 17;20(47):15330-3. doi: 10.1002/chem.201404084. Epub 2014 Oct 14.

PMID:
25313942
19.

Photoresponsive DNA nanocapsule having an open/close system for capture and release of nanomaterials.

Takenaka T, Endo M, Suzuki Y, Yang Y, Emura T, Hidaka K, Kato T, Miyata T, Namba K, Sugiyama H.

Chemistry. 2014 Nov 10;20(46):14951-4. doi: 10.1002/chem.201404757. Epub 2014 Sep 15.

PMID:
25223393
20.

Statistical inference based on the nonparametric maximum likelihood estimator under double-truncation.

Emura T, Konno Y, Michimae H.

Lifetime Data Anal. 2015 Jul;21(3):397-418. doi: 10.1007/s10985-014-9297-5. Epub 2014 Jul 8.

PMID:
25001399
21.

Identification of novel ALK rearrangement A2M-ALK in a neonate with fetal lung interstitial tumor.

Onoda T, Kanno M, Sato H, Takahashi N, Izumino H, Ohta H, Emura T, Katoh H, Ohizumi H, Ohtake H, Asao H, Dehner LP, Hill AD, Hayasaka K, Mitsui T.

Genes Chromosomes Cancer. 2014 Oct;53(10):865-74. doi: 10.1002/gcc.22199. Epub 2014 Jun 26.

PMID:
24965693
22.

Single-molecule mechanochemical sensing using DNA origami nanostructures.

Koirala D, Shrestha P, Emura T, Hidaka K, Mandal S, Endo M, Sugiyama H, Mao H.

Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8137-41. doi: 10.1002/anie.201404043. Epub 2014 Jun 16.

PMID:
24931175
23.

Helical DNA origami tubular structures with various sizes and arrangements.

Endo M, Yamamoto S, Emura T, Hidaka K, Morone N, Heuser JE, Sugiyama H.

Angew Chem Int Ed Engl. 2014 Jul 14;53(29):7484-90. doi: 10.1002/anie.201402973. Epub 2014 May 30.

PMID:
24888699
24.

Gene selection for survival data under dependent censoring: A copula-based approach.

Emura T, Chen YH.

Stat Methods Med Res. 2016 Dec;25(6):2840-2857. Epub 2014 May 11.

PMID:
24821000
25.

RNA-templated DNA origami structures.

Endo M, Yamamoto S, Tatsumi K, Emura T, Hidaka K, Sugiyama H.

Chem Commun (Camb). 2013 Apr 11;49(28):2879-81. doi: 10.1039/c3cc38804b.

PMID:
23446278
26.

Survival prediction based on compound covariate under Cox proportional hazard models.

Emura T, Chen YH, Chen HY.

PLoS One. 2012;7(10):e47627. doi: 10.1371/journal.pone.0047627. Epub 2012 Oct 24.

27.

Correlated evolution of phenotypic plasticity in metamorphic timing.

Michimae H, Emura T.

J Evol Biol. 2012 Jul;25(7):1331-9. doi: 10.1111/j.1420-9101.2012.02523.x. Epub 2012 Apr 24.

28.

Transcription regulation system mediated by mechanical operation of a DNA nanostructure.

Endo M, Miyazaki R, Emura T, Hidaka K, Sugiyama H.

J Am Chem Soc. 2012 Feb 15;134(6):2852-5. doi: 10.1021/ja2074856. Epub 2012 Jan 31.

PMID:
22283546
29.

Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold.

Endo M, Yang Y, Emura T, Hidaka K, Sugiyama H.

Chem Commun (Camb). 2011 Oct 14;47(38):10743-5. doi: 10.1039/c1cc13984c. Epub 2011 Aug 24.

PMID:
21869958
30.

Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors.

Kinoshita K, Ono Y, Emura T, Asoh K, Furuichi N, Ito T, Kawada H, Tanaka S, Morikami K, Tsukaguchi T, Sakamoto H, Tsukuda T, Oikawa N.

Bioorg Med Chem Lett. 2011 Jun 15;21(12):3788-93. doi: 10.1016/j.bmcl.2011.04.020. Epub 2011 Apr 22.

PMID:
21561771
31.

Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes.

Suzuki N, Emura T, Fukushima M.

Int J Oncol. 2011 Jul;39(1):263-70. doi: 10.3892/ijo.2011.1003. Epub 2011 Apr 13.

PMID:
21491084
32.

Two-dimensional DNA origami assemblies using a four-way connector.

Endo M, Sugita T, Rajendran A, Katsuda Y, Emura T, Hidaka K, Sugiyama H.

Chem Commun (Camb). 2011 Mar 21;47(11):3213-5. doi: 10.1039/c0cc05306f. Epub 2011 Feb 1.

PMID:
21286635
33.

Tracheal stenosis treated by division of the brachiocephalic artery: Report of a case.

Minagawa T, Oizumi H, Emura T, Sadahiro M.

Surg Today. 2010 Dec;40(12):1152-4. doi: 10.1007/s00595-009-4194-3. Epub 2010 Nov 26.

PMID:
21110159
34.

Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.

Yoshino H, Sato H, Shiraishi T, Tachibana K, Emura T, Honma A, Ishikura N, Tsunenari T, Watanabe M, Nishimoto A, Nakamura R, Nakagawa T, Ohta M, Takata N, Furumoto K, Kimura K, Kawata H.

Bioorg Med Chem. 2010 Dec 1;18(23):8150-7. doi: 10.1016/j.bmc.2010.10.023. Epub 2010 Oct 15.

PMID:
21050768
35.

Brain surface motion imaging to predict adhesions between meningiomas and the brain surface.

Taoka T, Yamada S, Yamatani Y, Akashi T, Miyasaka T, Emura T, Nakase H, Kichikawa K.

Neuroradiology. 2010 Nov;52(11):1003-10. doi: 10.1007/s00234-010-0671-z. Epub 2010 Mar 24.

PMID:
20333508
36.

Synthesis and optimization of hyaluronic acid-methotrexate conjugates to maximize benefit in the treatment of osteoarthritis.

Homma A, Sato H, Tamura T, Okamachi A, Emura T, Ishizawa T, Kato T, Matsuura T, Sato S, Higuchi Y, Watanabe T, Kitamura H, Asanuma K, Yamazaki T, Ikemi M, Kitagawa H, Morikawa T, Ikeya H, Maeda K, Takahashi K, Nohmi K, Izutani N, Kanda M, Suzuki R.

Bioorg Med Chem. 2010 Feb;18(3):1062-75. doi: 10.1016/j.bmc.2009.12.053. Epub 2009 Dec 28.

PMID:
20060728
37.

Novel hyaluronic acid-methotrexate conjugates for osteoarthritis treatment.

Homma A, Sato H, Okamachi A, Emura T, Ishizawa T, Kato T, Matsuura T, Sato S, Tamura T, Higuchi Y, Watanabe T, Kitamura H, Asanuma K, Yamazaki T, Ikemi M, Kitagawa H, Morikawa T, Ikeya H, Maeda K, Takahashi K, Nohmi K, Izutani N, Kanda M, Suzuki R.

Bioorg Med Chem. 2009 Jul 1;17(13):4647-56. doi: 10.1016/j.bmc.2009.04.063. Epub 2009 May 3.

PMID:
19457673
38.

Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.

Temmink OH, Emura T, de Bruin M, Fukushima M, Peters GJ.

Cancer Sci. 2007 Jun;98(6):779-89. Epub 2007 Apr 18. Review.

39.

Discovery of 7alpha-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure-activity relationships.

Tachibana K, Imaoka I, Yoshino H, Emura T, Kodama H, Furuta Y, Kato N, Nakamura M, Ohta M, Taniguchi K, Ishikura N, Nagamuta M, Onuma E, Sato H.

Bioorg Med Chem. 2007 Jan 1;15(1):174-85. Epub 2006 Oct 4.

PMID:
17064916
40.
41.

Design and evaluation of new antipsoriatic antedrug candidates having 16-en-22-oxa-vitamin D3 structures.

Shimizu K, Kawase A, Haneishi T, Kato Y, Kinoshita K, Ohmori M, Furuta Y, Emura T, Kato N, Mitsui T, Yamaguchi K, Morita K, Sekiguchi N, Yamamoto T, Matsushita T, Shimaoka S, Sugita A, Morikawa K.

Bioorg Med Chem Lett. 2006 Jun 15;16(12):3323-9. Epub 2006 Apr 21.

PMID:
16630723
43.

Gene sequences and specific detection for Panton-Valentine leukocidin.

Nakagawa S, Taneike I, Mimura D, Iwakura N, Nakayama T, Emura T, Kitatsuji M, Fujimoto A, Yamamoto T.

Biochem Biophys Res Commun. 2005 Mar 25;328(4):995-1002.

PMID:
15707976
44.

Ganglion of the groin in a child: an unusual cause of soft-tissue swelling of the groin.

Emura T, Yokomori K, Obana K, Tanaka Y.

Pediatr Surg Int. 2005 Mar;21(3):227-9. Epub 2004 Dec 9.

PMID:
15592851
45.

Omphalocele associated with a large multilobular umbilical cord pseudocyst.

Emura T, Kanamori Y, Ito M, Tanaka Y, Hashizume K, Marumo G, Goishi K.

Pediatr Surg Int. 2004 Aug;20(8):636-9. Epub 2004 Jul 28. Review.

PMID:
15449087
46.
47.

Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase.

Yano S, Kazuno H, Sato T, Suzuki N, Emura T, Wierzba K, Yamashita J, Tada Y, Yamada Y, Fukushima M, Asao T.

Bioorg Med Chem. 2004 Jul 1;12(13):3443-50.

PMID:
15186830
48.

Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase.

Yano S, Kazuno H, Suzuki N, Emura T, Wierzba K, Yamashita J, Tada Y, Yamada Y, Fukushima M, Asao T.

Bioorg Med Chem. 2004 Jul 1;12(13):3431-41.

PMID:
15186829
49.

A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.

Emura T, Murakami Y, Nakagawa F, Fukushima M, Kitazato K.

Int J Mol Med. 2004 Apr;13(4):545-9.

PMID:
15010854
50.

An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA.

Emura T, Nakagawa F, Fujioka A, Ohshimo H, Yokogawa T, Okabe H, Kitazato K.

Int J Mol Med. 2004 Feb;13(2):249-55.

PMID:
14719131

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