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Items: 1 to 50 of 417

1.

Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation.

Xia J, Broad KD, Emson PC, Keverne EB.

Neuroscience. 2010 Sep 1;169(3):1462-72. doi: 10.1016/j.neuroscience.2010.05.071. Epub 2010 Jun 8.

PMID:
20594945
2.

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease.

Salek RM, Xia J, Innes A, Sweatman BC, Adalbert R, Randle S, McGowan E, Emson PC, Griffin JL.

Neurochem Int. 2010 Jul;56(8):937-47. doi: 10.1016/j.neuint.2010.04.001. Epub 2010 Apr 14.

PMID:
20398713
3.

Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.

Clarke JH, Emson PC, Irvine RF.

J Comp Neurol. 2009 Nov 20;517(3):296-312. doi: 10.1002/cne.22161.

4.

Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease.

Higashi S, Moore DJ, Yamamoto R, Minegishi M, Sato K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Emson PC, Wada K, Dawson VL, Dawson TM, Arai H, Iseki E.

J Neuropathol Exp Neurol. 2009 Sep;68(9):994-1005. doi: 10.1097/NEN.0b013e3181b44ed8.

5.

Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice.

Helyes Z, Pintér E, Sándor K, Elekes K, Bánvölgyi A, Keszthelyi D, Szoke E, Tóth DM, Sándor Z, Kereskai L, Pozsgai G, Allen JP, Emson PC, Markovics A, Szolcsányi J.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13088-93. doi: 10.1073/pnas.0900681106. Epub 2009 Jul 21.

6.

Increased expression of the NR2A NMDA receptor subunit in the prefrontal cortex of rats reared in isolation.

Turnock-Jones JJ, Jennings CA, Robbins MJ, Cluderay JE, Cilia J, Reid JL, Taylor A, Jones DN, Emson PC, Southam E.

Synapse. 2009 Oct;63(10):836-46. doi: 10.1002/syn.20665.

PMID:
19533626
7.

Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron.

Clarke JH, Emson PC, Irvine RF.

Am J Physiol Renal Physiol. 2008 Nov;295(5):F1422-30. doi: 10.1152/ajprenal.90310.2008. Epub 2008 Aug 27.

8.

Reduced vesicular storage of dopamine exacerbates methamphetamine-induced neurodegeneration and astrogliosis.

Guillot TS, Shepherd KR, Richardson JR, Wang MZ, Li Y, Emson PC, Miller GW.

J Neurochem. 2008 Sep;106(5):2205-17. doi: 10.1111/j.1471-4159.2008.05568.x. Epub 2008 Jul 15.

9.

Altered vesicular dopamine storage in Parkinson's disease: a premature demise.

Caudle WM, Colebrooke RE, Emson PC, Miller GW.

Trends Neurosci. 2008 Jun;31(6):303-8. doi: 10.1016/j.tins.2008.02.010. Epub 2008 May 9. Review.

PMID:
18471904
10.

A metabolomic study of brain tissues from aged mice with low expression of the vesicular monoamine transporter 2 (VMAT2) gene.

Salek RM, Colebrooke RE, Macintosh R, Lynch PJ, Sweatman BC, Emson PC, Griffin JL.

Neurochem Res. 2008 Feb;33(2):292-300. Epub 2007 Nov 29.

PMID:
18041582
11.

Glutamate uptake is reduced in prefrontal cortex in Huntington's disease.

Hassel B, Tessler S, Faull RL, Emson PC.

Neurochem Res. 2008 Feb;33(2):232-7. Epub 2007 Aug 29.

PMID:
17726644
12.

Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration.

Caudle WM, Richardson JR, Wang MZ, Taylor TN, Guillot TS, McCormack AL, Colebrooke RE, Di Monte DA, Emson PC, Miller GW.

J Neurosci. 2007 Jul 25;27(30):8138-48.

13.

Impairments in impulse control in mice transgenic for the human FTDP-17 tauV337M mutation are exacerbated by age.

Lambourne SL, Humby T, Isles AR, Emson PC, Spillantini MG, Wilkinson LS.

Hum Mol Genet. 2007 Jul 15;16(14):1708-19. Epub 2007 May 20.

PMID:
17517691
14.

Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.

Higashi S, Biskup S, West AB, Trinkaus D, Dawson VL, Faull RL, Waldvogel HJ, Arai H, Dawson TM, Moore DJ, Emson PC.

Brain Res. 2007 Jun 25;1155:208-19. Epub 2007 Apr 19.

PMID:
17512502
15.

GABA(B) receptors: structure and function.

Emson PC.

Prog Brain Res. 2007;160:43-57. Review.

PMID:
17499108
16.

Differential gene expression in the striatum of mice with very low expression of the vesicular monoamine transporter type 2 gene.

Colebrooke RE, Chan PM, Lynch PJ, Mooslehner K, Emson PC.

Brain Res. 2007 Jun 4;1152:10-6. Epub 2007 Mar 15.

PMID:
17433807
17.

Localization of LRRK2 to membranous and vesicular structures in mammalian brain.

Biskup S, Moore DJ, Celsi F, Higashi S, West AB, Andrabi SA, Kurkinen K, Yu SW, Savitt JM, Waldvogel HJ, Faull RL, Emson PC, Torp R, Ottersen OP, Dawson TM, Dawson VL.

Ann Neurol. 2006 Nov;60(5):557-69.

PMID:
17120249
18.

Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease.

Brooks WM, Lynch PJ, Ingle CC, Hatton A, Emson PC, Faull RL, Starkey MP.

Brain Res. 2007 Jan 5;1127(1):127-35. Epub 2006 Nov 15.

PMID:
17109828
19.

Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.

Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC.

J Neurochem. 2007 Jan;100(2):368-81. Epub 2006 Nov 13.

20.
21.

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG.

J Neurosci. 2006 Apr 12;26(15):3942-50.

22.

Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model.

Jeong YH, Park CH, Yoo J, Shin KY, Ahn SM, Kim HS, Lee SH, Emson PC, Suh YH.

FASEB J. 2006 Apr;20(6):729-31. Epub 2006 Feb 8.

PMID:
16467370
23.

Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo.

Zhang Y, Bo X, Schoepfer R, Holtmaat AJ, Verhaagen J, Emson PC, Lieberman AR, Anderson PN.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14883-8. Epub 2005 Sep 29.

25.

Expression of nNOS and soluble guanylate cyclase in schizophrenic brain.

Baba H, Suzuki T, Arai H, Emson PC.

Neuroreport. 2004 Mar 22;15(4):677-80.

PMID:
15094474
27.
28.

Immunological function in mice lacking the Rac-related GTPase RhoG.

Vigorito E, Bell S, Hebeis BJ, Reynolds H, McAdam S, Emson PC, McKenzie A, Turner M.

Mol Cell Biol. 2004 Jan;24(2):719-29.

29.

GPR105, a novel Gi/o-coupled UDP-glucose receptor expressed on brain glia and peripheral immune cells, is regulated by immunologic challenge: possible role in neuroimmune function.

Moore DJ, Murdock PR, Watson JM, Faull RL, Waldvogel HJ, Szekeres PG, Wilson S, Freeman KB, Emson PC.

Brain Res Mol Brain Res. 2003 Oct 21;118(1-2):10-23.

PMID:
14559350
30.

Immunohistochemical study of brain-derived neurotrophic factor and its receptor, TrkB, in the hippocampal formation of schizophrenic brains.

Iritani S, Niizato K, Nawa H, Ikeda K, Emson PC.

Prog Neuropsychopharmacol Biol Psychiatry. 2003 Aug;27(5):801-7.

PMID:
12921913
31.

Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum.

Allen JP, Hathway GJ, Clarke NJ, Jowett MI, Topps S, Kendrick KM, Humphrey PP, Wilkinson LS, Emson PC.

Eur J Neurosci. 2003 May;17(9):1881-95.

PMID:
12752788
32.

Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice.

Patel J, Mooslehner KA, Chan PM, Emson PC, Stamford JA.

J Neurochem. 2003 May;85(4):898-910.

33.

GABAB receptor subunits, R1 and R2, in brainstem catecholamine and serotonin neurons.

Burman KJ, Ige AO, White JH, Marshall FH, Pangalos MN, Emson PC, Minson JB, Llewellyn-Smith IJ.

Brain Res. 2003 Apr 25;970(1-2):35-46.

PMID:
12706246
34.

Expression of Fyn, a non-receptor tyrosine kinase in prefrontal cortex from patients with schizophrenia and its correlation with clinical onset.

Ohnuma T, Kato H, Arai H, McKenna PJ, Emson PC.

Brain Res Mol Brain Res. 2003 Apr 10;112(1-2):90-4.

PMID:
12670706
35.

Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice.

Allen JP, Canty AJ, Schulz S, Humphrey PP, Emson PC, Young HM.

J Comp Neurol. 2002 Dec 16;454(3):329-40.

PMID:
12442323
36.

Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.

Moore DJ, Chambers JK, Murdock PR, Emson PC.

Neuropharmacology. 2002 Nov;43(6):966-78.

PMID:
12423666
37.

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, Goedert M.

J Neurosci. 2002 Nov 1;22(21):9340-51.

38.

Non-radioactive in situ hybridization using alkaline phosphatase-labelled oligonucleotides.

Augood SJ, McGowan EM, Finsen BR, Heppelmann B, Emson PC.

Int Rev Neurobiol. 2002;47:173-201. Review. No abstract available.

PMID:
12198799
39.

Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22.

Mimmack ML, Ryan M, Baba H, Navarro-Ruiz J, Iritani S, Faull RL, McKenna PJ, Jones PB, Arai H, Starkey M, Emson PC, Bahn S.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4680-5.

40.

Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs.

Freeman K, Tsui P, Moore D, Emson PC, Vawter L, Naheed S, Lane P, Bawagan H, Herrity N, Murphy K, Sarau HM, Ames RS, Wilson S, Livi GP, Chambers JK.

Genomics. 2001 Dec;78(3):124-8.

PMID:
11735218
41.

Reduction of glial glutamate transporters in the parietal cortex and hippocampus of the EL mouse.

Ingram EM, Wiseman JW, Tessler S, Emson PC.

J Neurochem. 2001 Nov;79(3):564-75.

42.

Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study.

Moore DJ, Chambers JK, Wahlin JP, Tan KB, Moore GB, Jenkins O, Emson PC, Murdock PR.

Biochim Biophys Acta. 2001 Oct 31;1521(1-3):107-19.

PMID:
11690642
43.
44.

Changes in the mRNAs encoding voltage-gated sodium channel types II and III in human epileptic hippocampus.

Whitaker WR, Faull RL, Dragunow M, Mee EW, Emson PC, Clare JJ.

Neuroscience. 2001;106(2):275-85.

PMID:
11566500
45.

Gene expression profiling in the post-mortem human brain--no cause for dismay.

Bahn S, Augood SJ, Ryan M, Standaert DG, Starkey M, Emson PC.

J Chem Neuroanat. 2001 Jul;22(1-2):79-94. Review.

PMID:
11470556
46.

Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism.

Mooslehner KA, Chan PM, Xu W, Liu L, Smadja C, Humby T, Allen ND, Wilkinson LS, Emson PC.

Mol Cell Biol. 2001 Aug;21(16):5321-31.

47.

Advances in the molecular understanding of GABA(B) receptors.

Billinton A, Ige AO, Bolam JP, White JH, Marshall FH, Emson PC.

Trends Neurosci. 2001 May;24(5):277-82. Review.

PMID:
11311380
48.

Comparative distribution of voltage-gated sodium channel proteins in human brain.

Whitaker WR, Faull RL, Waldvogel HJ, Plumpton CJ, Emson PC, Clare JJ.

Brain Res Mol Brain Res. 2001 Mar 31;88(1-2):37-53.

PMID:
11295230
49.

Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus.

Ohnuma T, Tessler S, Arai H, Faull RL, McKenna PJ, Emson PC.

Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):24-31.

PMID:
11146103
50.

The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx.

White JH, McIllhinney RA, Wise A, Ciruela F, Chan WY, Emson PC, Billinton A, Marshall FH.

Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13967-72.

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