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Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe/PS1dE9 mouse model of Alzheimer's disease.

Saito T, Hisahara S, Iwahara N, Emoto MC, Yokokawa K, Suzuki H, Manabe T, Matsumura A, Suzuki S, Matsushita T, Kawamata J, Sato-Akaba H, Fujii HG, Shimohama S.

Free Radic Biol Med. 2019 Sep 16;145:20-32. doi: 10.1016/j.freeradbiomed.2019.09.014. [Epub ahead of print]


Molecular Dynamics Simulation of the Influence of Nanoscale Structure on Water Wetting and Condensation.

Hiratsuka M, Emoto M, Konno A, Ito S.

Micromachines (Basel). 2019 Aug 31;10(9). pii: E587. doi: 10.3390/mi10090587.


Superiority of glycated albumin over glycated haemoglobin as indicator of glycaemic control and predictor of all-cause mortality in patients with type 2 diabetes mellitus receiving peritoneal dialysis.

Miyabe M, Kurajoh M, Mori K, Okuno S, Okada S, Emoto M, Tsujimoto Y, Inaba M.

Ann Clin Biochem. 2019 Sep 7:4563219873688. doi: 10.1177/0004563219873688. [Epub ahead of print] No abstract available.


Thyroid blood flow in inferior thyroid artery as predictor for increase in levothyroxine dosage during pregnancy in women with Hashimoto's thyroiditis - a retrospective study.

Kurajoh M, Yamasaki A, Nagasaki T, Nagata Y, Yamada S, Imanishi Y, Emoto M, Takahashi K, Yamamoto K, Shintani A, Inaba M.

BMC Pregnancy Childbirth. 2019 Jul 5;19(1):232. doi: 10.1186/s12884-019-2389-1.


Denosumab Improves Glomerular Filtration Rate in Osteoporotic Patients With Normal Kidney Function by Lowering Serum Phosphorus.

Miyaoka D, Inaba M, Imanishi Y, Hayashi N, Ohara M, Nagata Y, Kurajoh M, Yamada S, Mori K, Emoto M.

J Bone Miner Res. 2019 Jul 5. doi: 10.1002/jbmr.3821. [Epub ahead of print]


Oncostatin M induces C2C12 myotube atrophy by modulating muscle differentiation and degradation.

Miki Y, Morioka T, Shioi A, Fujimoto K, Sakura T, Uedono H, Kakutani Y, Ochi A, Mori K, Shoji T, Emoto M, Inaba M.

Biochem Biophys Res Commun. 2019 Aug 27;516(3):951-956. doi: 10.1016/j.bbrc.2019.06.143. Epub 2019 Jul 2.


Independent association of plasma xanthine oxidoreductase activity with serum uric acid level based on stable isotope-labeled xanthine and liquid chromatography/triple quadrupole mass spectrometry: MedCity21 health examination registry.

Kurajoh M, Fukumoto S, Emoto M, Murase T, Nakamura T, Ishihara T, Go H, Yamamoto K, Nakatani S, Tsuda A, Yamada S, Morioka T, Mori K, Imanishi Y, Inaba M.

Clin Chem Lab Med. 2019 May 14. pii: /j/cclm.ahead-of-print/cclm-2019-0199/cclm-2019-0199.xml. doi: 10.1515/cclm-2019-0199. [Epub ahead of print]


Inverse association of plasma leptin with cortical thickness at distal radius determined with a quantitative ultrasound device in patients with type 2 diabetes mellitus.

Kurajoh M, Inaba M, Motoyama K, Kuriyama N, Ozaki E, Koyama T, Yamada S, Morioka T, Imanishi Y, Emoto M.

J Diabetes Investig. 2019 May 9. doi: 10.1111/jdi.13071. [Epub ahead of print]


Aerobic Exercise Training with Brisk Walking Increases Intestinal Bacteroides in Healthy Elderly Women.

Morita E, Yokoyama H, Imai D, Takeda R, Ota A, Kawai E, Hisada T, Emoto M, Suzuki Y, Okazaki K.

Nutrients. 2019 Apr 17;11(4). pii: E868. doi: 10.3390/nu11040868.


Impact of diabetes on sarcopenia and mortality in patients undergoing hemodialysis.

Mori K, Nishide K, Okuno S, Shoji T, Emoto M, Tsuda A, Nakatani S, Imanishi Y, Ishimura E, Yamakawa T, Shoji S, Inaba M.

BMC Nephrol. 2019 Mar 28;20(1):105. doi: 10.1186/s12882-019-1271-8.


Novel increasing dose regimen of tolvaptan for autosomal dominant polycystic kidney disease in patient with low tolerability.

Nakatani S, Ishimura E, Machiba Y, Nakatani A, Fujimoto K, Uedono H, Okute Y, Tsuda A, Mori K, Emoto M, Inaba M.

Nephrology (Carlton). 2018 Aug;23(8):798-799. doi: 10.1111/nep.13196. No abstract available.


Attenuated Dentin Matrix Protein 1 Enhances Fibroblast Growth Factor 23 in Calvaria in a Primary Hyperparathyroidism Model.

Nagata Y, Imanishi Y, Ohara M, Maeda-Tateishi T, Miyaoka D, Hayashi N, Kurajoh M, Emoto M, Inaba M.

Endocrinology. 2019 May 1;160(5):1348-1358. doi: 10.1210/en.2019-00017.


Significance of urinary C-megalin excretion in vitamin D metabolism in pre-dialysis CKD patients.

Toi N, Inaba M, Ishimura E, Tsugawa N, Imanishi Y, Emoto M, Hirayama Y, Nakatani S, Saito A, Yamada S.

Sci Rep. 2019 Feb 18;9(1):2207. doi: 10.1038/s41598-019-38613-8.


Evaluation of Mitochondrial Oxidative Stress in the Brain of a Transgenic Mouse Model of Alzheimer's Disease by in vitro Electron Paramagnetic Resonance Spectroscopy.

Manabe T, Matsumura A, Yokokawa K, Saito T, Fujikura M, Iwahara N, Matsushita T, Suzuki S, Hisahara S, Kawamata J, Suzuki H, Emoto MC, Fujii HG, Shimohama S.

J Alzheimers Dis. 2019;67(3):1079-1087. doi: 10.3233/JAD-180985.


Plasma omentin levels are associated with vascular endothelial function in patients with type 2 diabetes at elevated cardiovascular risk.

Hayashi M, Morioka T, Hatamori M, Kakutani Y, Yamazaki Y, Kurajoh M, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Emoto M, Inaba M.

Diabetes Res Clin Pract. 2019 Feb;148:160-168. doi: 10.1016/j.diabres.2019.01.009. Epub 2019 Jan 11.


Improvement of glycemic control by treatment for insomnia with suvorexant in type 2 diabetes mellitus.

Toi N, Inaba M, Kurajoh M, Morioka T, Hayashi N, Hirota T, Miyaoka D, Emoto M, Yamada S.

J Clin Transl Endocrinol. 2018 Dec 18;15:37-44. doi: 10.1016/j.jcte.2018.12.006. eCollection 2019 Mar.


Visualization of Blood Glucose Fluctuations Using Continuous Glucose Monitoring in Patients Undergoing Hemodialysis.

Mori K, Emoto M, Abe M, Inaba M.

J Diabetes Sci Technol. 2019 Mar;13(2):413-414. doi: 10.1177/1932296818818429. Epub 2018 Dec 23. No abstract available.


Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial.

J-DAVID Investigators, Shoji T, Inaba M, Fukagawa M, Ando R, Emoto M, Fujii H, Fujimori A, Fukui M, Hase H, Hashimoto T, Hirakata H, Honda H, Hosoya T, Ikari Y, Inaguma D, Inoue T, Isaka Y, Iseki K, Ishimura E, Itami N, Ito C, Kakuta T, Kawai T, Kawanishi H, Kobayashi S, Kumagai J, Maekawa K, Masakane I, Minakuchi J, Mitsuiki K, Mizuguchi T, Morimoto S, Murohara T, Nakatani T, Negi S, Nishi S, Nishikawa M, Ogawa T, Ohta K, Ohtake T, Okamura M, Okuno S, Shigematsu T, Sugimoto T, Suzuki M, Tahara H, Takemoto Y, Tanaka K, Tominaga Y, Tsubakihara Y, Tsujimoto Y, Tsuruya K, Ueda S, Watanabe Y, Yamagata K, Yamakawa T, Yano S, Yokoyama K, Yorioka N, Yoshiyama M, Nishizawa Y.

JAMA. 2018 Dec 11;320(22):2325-2334. doi: 10.1001/jama.2018.17749.


Non-mercaptalbumin, Oxidized Form of Serum Albumin, Significantly Associated with Renal Function and Anemia in Chronic Kidney Disease Patients.

Nakatani S, Yasukawa K, Ishimura E, Nakatani A, Toi N, Uedono H, Tsuda A, Yamada S, Ikeda H, Mori K, Emoto M, Yatomi Y, Inaba M.

Sci Rep. 2018 Nov 14;8(1):16796. doi: 10.1038/s41598-018-35177-x.


Microwave frequency comb Doppler reflectometer applying fast digital data acquisition system in LHD.

Tokuzawa T, Tsuchiya H, Tsujimura T, Emoto M, Nakanishi H, Inagaki S, Ida K, Yamada H, Ejiri A, Watanabe KY, Oguri K, Akiyama T, Tanaka K, Yamada I; LHD Experiment Group.

Rev Sci Instrum. 2018 Oct;89(10):10H118. doi: 10.1063/1.5035118.


Elucidation of Racemization Process of Azaspirene Skeleton in Neutral Aqueous Media.

Hirasawa S, Mukai K, Sakai S, Wakamori S, Hasegawa T, Souma K, Kanomata N, Ogawa N, Aizawa M, Emoto M.

J Org Chem. 2018 Dec 7;83(23):14457-14464. doi: 10.1021/acs.joc.8b02223. Epub 2018 Nov 13.


Protein kinase C iota facilitates insulin-induced glucose transport by phosphorylation of soluble nSF attachment protein receptor regulator (SNARE) double C2 domain protein b.

Nomiyama R, Emoto M, Fukuda N, Matsui K, Kondo M, Sakane A, Sasaki T, Tanizawa Y.

J Diabetes Investig. 2019 May;10(3):591-601. doi: 10.1111/jdi.12965. Epub 2018 Dec 1.


Non-invasive mapping of glutathione levels in mouse brains by in vivo electron paramagnetic resonance (EPR) imaging: Applied to a kindling mouse model.

Emoto MC, Sato-Akaba H, Matsuoka Y, Yamada KI, Fujii HG.

Neurosci Lett. 2019 Jan 18;690:6-10. doi: 10.1016/j.neulet.2018.10.001. Epub 2018 Oct 2.


Inhibitory Effects of Intranasal Administration of Insulin on Fat Oxidation during Exercise Are Diminished in Young Overweight Individuals.

Yokoyama H, Takeda R, Kawai E, Ota A, Morita E, Imai D, Suzuki Y, Morioka T, Emoto M, Inaba M, Okazaki K.

J Clin Med. 2018 Sep 28;7(10). pii: E308. doi: 10.3390/jcm7100308.


Association of Albuminuria With Intraglomerular Hydrostatic Pressure and Insulin Resistance in Subjects With Impaired Fasting Glucose and/or Impaired Glucose Tolerance.

Tsuda A, Ishimura E, Uedono H, Ochi A, Nakatani S, Morioka T, Mori K, Uchida J, Emoto M, Nakatani T, Inaba M.

Diabetes Care. 2018 Nov;41(11):2414-2420. doi: 10.2337/dc18-0718. Epub 2018 Sep 13.


Impaired residual renal function predicts denosumab-induced serum calcium decrement as well as increment of bone mineral density in non-severe renal insufficiency.

Miyaoka D, Imanishi Y, Ohara M, Hayashi N, Nagata Y, Yamada S, Mori K, Emoto M, Inaba M.

Osteoporos Int. 2019 Jan;30(1):241-249. doi: 10.1007/s00198-018-4688-1. Epub 2018 Sep 5.


Synthesis and Evaluation as a Blood-Brain Barrier-Permeable Probe of 7-N-(PROXYL-3-yl-methyl)theophylline.

Emoto MC, Sasaki K, Maeda K, Fujii HG, Sato S.

Chem Pharm Bull (Tokyo). 2018;66(9):887-891. doi: 10.1248/cpb.c18-00333.


Association of Decreased Handgrip Strength with Reduced Cortical Thickness in Japanese Female Patients with Type 2 Diabetes Mellitus.

Nakamura M, Inaba M, Yamada S, Ozaki E, Maruo S, Okuno S, Imanishi Y, Kuriyama N, Watanabe Y, Emoto M, Motoyama K.

Sci Rep. 2018 Jul 17;8(1):10767. doi: 10.1038/s41598-018-29061-x.


Fulminant onset of insulin-dependent diabetes with positive anti-GAD antibody titers during treatment with nivolumab in a patient with NSCLC.

Matsuura N, Koh G, Konishi C, Minamino S, Takahara Y, Harada H, Kodama K, Emoto M.

Cancer Immunol Immunother. 2018 Sep;67(9):1417-1424. doi: 10.1007/s00262-018-2203-3. Epub 2018 Jul 11.


Plasma polyunsaturated fatty acid profile is associated with vascular endothelial function in patients with type 2 diabetes.

Morioka T, Emoto M, Imamura S, Kakutani Y, Yamazaki Y, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M.

Diab Vasc Dis Res. 2018 Jul;15(4):352-355. doi: 10.1177/1479164118774314.


The Efficacy of Low-Density Lipoprotein Apheresis in a Patient with Drug-Resistant Minimal Change Nephrotic Syndrome: A Case Report and A Review of the Literature.

Nakatani S, Ishimura E, Okute Y, Nakatani A, Uedono H, Tsuda A, Naganuma T, Takemoto Y, Mori K, Emoto M, Inaba M.

Nephrology (Carlton). 2018 Jun;23(6):603-604. doi: 10.1111/nep.13120. Review. No abstract available.


Urinary Iron Excretion is Associated with Urinary Full-Length Megalin and Renal Oxidative Stress in Chronic Kidney Disease.

Nakatani S, Nakatani A, Ishimura E, Toi N, Tsuda A, Mori K, Emoto M, Hirayama Y, Saito A, Inaba M.

Kidney Blood Press Res. 2018;43(2):458-470. doi: 10.1159/000488470. Epub 2018 Mar 22.


Correlation analysis of monocyte subsets and insulin resistance considering fetuin-A involvement in patients with type 2 diabetes.

Maruo S, Mori K, Motoyama K, Nakamura M, Kawarabayashi R, Kakutani Y, Yamazaki Y, Morioka T, Shoji T, Inaba M, Emoto M.

Clin Transl Med. 2018 Mar 27;7(1):9. doi: 10.1186/s40169-018-0187-4.


Positive association of plasma leptin with sleep quality in obese type 2 diabetes patients.

Hirota T, Morioka T, Yoda K, Toi N, Hayashi N, Maruo S, Yamazaki Y, Kurajoh M, Motoyama K, Yamada S, Shoji T, Emoto M, Inaba M.

J Diabetes Investig. 2018 Sep;9(5):1100-1105. doi: 10.1111/jdi.12826. Epub 2018 Mar 26.


Association of cystatin C- and creatinine-based eGFR with osteoporotic fracture in Japanese postmenopausal women with osteoporosis: sarcopenia as risk for fracture.

Kurajoh M, Inaba M, Nagata Y, Yamada S, Imanishi Y, Emoto M.

J Bone Miner Metab. 2019 Mar;37(2):282-291. doi: 10.1007/s00774-018-0913-4. Epub 2018 Feb 20.


The Association between Monocyte Surface CD163 and Insulin Resistance in Patients with Type 2 Diabetes.

Kawarabayashi R, Motoyama K, Nakamura M, Yamazaki Y, Morioka T, Mori K, Fukumoto S, Imanishi Y, Shioi A, Shoji T, Emoto M, Inaba M.

J Diabetes Res. 2017;2017:6549242. doi: 10.1155/2017/6549242. Epub 2017 Dec 28.


Association of heterogeneity of the thyroid gland with matrix metalloproteinase-3 in rheumatoid arthritis patients with Hashimoto's thyroiditis.

Nagasaki T, Nagata Y, Wakita Y, Yamada S, Goto H, Imanishi Y, Onoda N, Emoto M, Inaba M.

Minerva Endocrinol. 2018 Dec;43(4):398-405. doi: 10.23736/S0391-1977.18.02725-6. Epub 2018 Feb 13.


Development of hyperkalemia following treatment with dapagliflozin (DAPA) in a patient with type 2 diabetes after bilateral adrenalectomy.

Miyaoka D, Tsuda A, Hayashi N, Toi N, Yamasaki A, Nagata Y, Nakatani S, Kurajoh M, Yamada S, Morioka T, Imanishi Y, Emoto M, Inaba M.

CEN Case Rep. 2018 May;7(1):29-33. doi: 10.1007/s13730-017-0286-x. Epub 2017 Nov 13.


Xanthine oxidoreductase activity is associated with serum uric acid and glycemic control in hemodialysis patients.

Nakatani A, Nakatani S, Ishimura E, Murase T, Nakamura T, Sakura M, Tateishi Y, Tsuda A, Kurajoh M, Mori K, Emoto M, Inaba M.

Sci Rep. 2017 Nov 13;7(1):15416. doi: 10.1038/s41598-017-15419-0.


Altered Serum n-6 Polyunsaturated Fatty Acid Profile and Risks of Mortality and Cardiovascular Events in a Cohort of Hemodialysis Patients.

Kuwamura Y, Shoji T, Okute Y, Yamazaki Y, Motoyama K, Morioka T, Mori K, Fukumoto S, Tsujimoto Y, Shioi A, Emoto M, Inaba M.

J Ren Nutr. 2018 Jan;28(1):54-63. doi: 10.1053/j.jrn.2017.07.001. Epub 2017 Oct 28.


Design and testing of a 750MHz CW-EPR digital console for small animal imaging.

Sato-Akaba H, Emoto MC, Hirata H, Fujii HG.

J Magn Reson. 2017 Nov;284:48-58. doi: 10.1016/j.jmr.2017.09.008. Epub 2017 Sep 20.


Novel analysis technique for measuring edge density fluctuation profiles with reflectometry in the Large Helical Device.

Creely AJ, Ida K, Yoshinuma M, Tokuzawa T, Tsujimura T, Akiyama T, Sakamoto R, Emoto M, Tanaka K, Michael CA.

Rev Sci Instrum. 2017 Jul;88(7):073509. doi: 10.1063/1.4993437.


Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus.

Sonoda M, Shoji T, Kuwamura Y, Okute Y, Naganuma T, Shima H, Motoyama K, Morioka T, Mori K, Fukumoto S, Shioi A, Shimono T, Fujii H, Kabata D, Shintani A, Emoto M, Inaba M.

Sci Rep. 2017 Jun 29;7(1):4382. doi: 10.1038/s41598-017-04515-w.


Effects of Teriparatide and Sequential Minodronate on Lumbar Spine Bone Mineral Density and Microarchitecture in Osteoporosis.

Miyaoka D, Imanishi Y, Ohara M, Hayashi N, Nagata Y, Yamada S, Mori K, Emoto M, Inaba M.

Calcif Tissue Int. 2017 Oct;101(4):396-403. doi: 10.1007/s00223-017-0295-y. Epub 2017 Jun 6.


Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study.

Sakura T, Morioka T, Shioi A, Kakutani Y, Miki Y, Yamazaki Y, Motoyama K, Mori K, Fukumoto S, Shoji T, Emoto M, Inaba M.

Cardiovasc Diabetol. 2017 May 10;16(1):62. doi: 10.1186/s12933-017-0545-3.



Mori K, Emoto M, Numaguchi R, Yamazaki Y, Urata H, Motoyama K, Morioka T, Shoji T, Inaba M.

Acta Endocrinol (Buchar). 2017 Apr-Jun;13(2):133-137. doi: 10.4183/aeb.2017.133.


Plasma soluble leptin receptor levels are associated with pancreatic β-cell dysfunction in patients with type 2 diabetes.

Morioka T, Emoto M, Yamazaki Y, Kurajoh M, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M.

J Diabetes Investig. 2018 Jan;9(1):55-62. doi: 10.1111/jdi.12657. Epub 2017 Apr 25.


Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging.

Emoto MC, Matsuoka Y, Yamada KI, Sato-Akaba H, Fujii HG.

Biochem Biophys Res Commun. 2017 Apr 15;485(4):802-806. doi: 10.1016/j.bbrc.2017.02.134. Epub 2017 Feb 28.


U-shaped relationship between serum uric acid levels and intrarenal hemodynamic parameters in healthy subjects.

Uedono H, Tsuda A, Ishimura E, Nakatani S, Kurajoh M, Mori K, Uchida J, Emoto M, Nakatani T, Inaba M.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F992-F997. doi: 10.1152/ajprenal.00645.2016. Epub 2017 Mar 1.


Plasma C1q/TNF-Related Protein-9 Levels Are Associated with Atherosclerosis in Patients with Type 2 Diabetes without Renal Dysfunction.

Asada M, Morioka T, Yamazaki Y, Kakutani Y, Kawarabayashi R, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Emoto M, Inaba M.

J Diabetes Res. 2016;2016:8624313. doi: 10.1155/2016/8624313. Epub 2016 Dec 14.

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