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Items: 1 to 50 of 83

1.

Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes.

Miani M, Le Naour J, Waeckel-Enée E, Verma SC, Straube M, Emond P, Ryffel B, van Endert P, Sokol H, Diana J.

Cell Metab. 2018 Jul 2. pii: S1550-4131(18)30394-2. doi: 10.1016/j.cmet.2018.06.012. [Epub ahead of print]

PMID:
30017352
2.

Validation of metabolomics analysis of human perilymph fluid using liquid chromatography-mass spectroscopy.

Mavel S, Lefèvre A, Bakhos D, Dufour-Rainfray D, Blasco H, Emond P.

Hear Res. 2018 May 22. pii: S0378-5955(17)30224-1. doi: 10.1016/j.heares.2018.05.016. [Epub ahead of print]

PMID:
29871827
3.

ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics.

Wei L, Syed Mortadza SA, Yan J, Zhang L, Wang L, Yin Y, Li C, Chalon S, Emond P, Belzung C, Li D, Lu C, Roger S, Jiang LH.

Neurosci Biobehav Rev. 2018 Apr;87:192-205. doi: 10.1016/j.neubiorev.2018.02.005. Epub 2018 Feb 14. Review.

PMID:
29453990
4.

The Metabolic Disturbances of Motoneurons Exposed to Glutamate.

Madji Hounoum B, Blasco H, Coque E, Vourc'h P, Emond P, Corcia P, Andres CR, Raoul C, Mavel S.

Mol Neurobiol. 2018 Feb 12. doi: 10.1007/s12035-018-0945-8. [Epub ahead of print]

PMID:
29435916
5.

Identification of metabolic pathway disturbances using multimodal metabolomics in autistic disorders in a Middle Eastern population.

Bitar T, Mavel S, Emond P, Nadal-Desbarats L, Lefèvre A, Mattar H, Soufia M, Blasco H, Vourc'h P, Hleihel W, Andres CR.

J Pharm Biomed Anal. 2018 Apr 15;152:57-65. doi: 10.1016/j.jpba.2018.01.007. Epub 2018 Feb 3.

PMID:
29414019
6.

The combination of four analytical methods to explore skeletal muscle metabolomics: Better coverage of metabolic pathways or a marketing argument?

Bruno C, Patin F, Bocca C, Nadal-Desbarats L, Bonnier F, Reynier P, Emond P, Vourc'h P, Joseph-Delafont K, Corcia P, Andres CR, Blasco H.

J Pharm Biomed Anal. 2018 Jan 30;148:273-279. doi: 10.1016/j.jpba.2017.10.013. Epub 2017 Oct 18.

PMID:
29059617
7.

An UPLC-MSMS method to measure plasma homocysteine concentration.

Vayne C, Deroche L, Drillaud N, Patin F, Bruno C, Maillot F, Labarthe F, Corcia P, Benz-de Bretagne I, Andres CR, Emond P, Blasco H.

Ann Biol Clin (Paris). 2017 Jun 1;75(3):334-338. doi: 10.1684/abc.2017.1248.

PMID:
28540856
8.

Single nucleotide polymorphisms of ABCC2 modulate renal secretion of endogenous organic anions.

Muhrez K, Largeau B, Emond P, Montigny F, Halimi JM, Trouillas P, Barin-Le Guellec C.

Biochem Pharmacol. 2017 Sep 15;140:124-138. doi: 10.1016/j.bcp.2017.05.012. Epub 2017 May 19.

PMID:
28532626
9.

Workflow methodology for rat brain metabolome exploration using NMR, LC-MS and GC-MS analytical platforms.

Diémé B, Lefèvre A, Nadal-Desbarats L, Galineau L, Madji Hounoum B, Montigny F, Blasco H, Andres CR, Emond P, Mavel S.

J Pharm Biomed Anal. 2017 Aug 5;142:270-278. doi: 10.1016/j.jpba.2017.03.068. Epub 2017 May 13.

PMID:
28531831
10.

Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model.

Foucault-Fruchard L, Doméné A, Page G, Windsor M, Emond P, Rodrigues N, Dollé F, Damont A, Buron F, Routier S, Chalon S, Antier D.

Neuroscience. 2017 Jul 25;356:52-63. doi: 10.1016/j.neuroscience.2017.05.019. Epub 2017 May 18.

PMID:
28527955
11.

Erratum to "Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management" [Clin. Biochem. 49 (2016) 1047-1050].

Bruno C, Dufour-Rainfray D, Patin F, Vourc'h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres CR, Emond P, Blasco H.

Clin Biochem. 2017 Jun;50(9):546. doi: 10.1016/j.clinbiochem.2017.03.023. Epub 2017 May 2. No abstract available.

PMID:
28366684
12.

Hyperphenylalaninemia Correlated with Global Decrease of Antioxidant Genes Expression in White Blood Cells of Adult Patients with Phenylketonuria.

Veyrat-Durebex C, Debeissat C, Blasco H, Patin F, Henique H, Emond P, Antar C, Gissot V, Herault O, Maillot F.

JIMD Rep. 2017;37:73-83. doi: 10.1007/8904_2017_16. Epub 2017 Mar 15.

13.

Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling.

Madji Hounoum B, Mavel S, Coque E, Patin F, Vourc'h P, Marouillat S, Nadal-Desbarats L, Emond P, Corcia P, Andres CR, Raoul C, Blasco H.

Glia. 2017 Apr;65(4):592-605. doi: 10.1002/glia.23114. Epub 2017 Jan 31.

PMID:
28139855
14.

Correction: Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1H NMR and GC-MS approach.

Muhrez K, Nadal-Desbarats L, Halimi JM, Dieme B, Büchler M, Emond P, Blasco H, Le Guellec C.

Mol Biosyst. 2017 Jan 31;13(2):432. doi: 10.1039/c7mb90005h.

PMID:
28102871
15.

Specific Metabolome Profile of Exhaled Breath Condensate in Patients with Shock and Respiratory Failure: A Pilot Study.

Fermier B, Blasco H, Godat E, Bocca C, Moënne-Loccoz J, Emond P, Andres CR, Laffon M, Ferrandière M.

Metabolites. 2016 Sep 1;6(3). pii: E26. doi: 10.3390/metabo6030026.

16.

Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management.

Bruno C, Dufour-Rainfray D, Patin F, Vourc'h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres CR, Emond P, Blasco H.

Clin Biochem. 2016 Sep;49(13-14):1047-50. doi: 10.1016/j.clinbiochem.2016.07.008. Epub 2016 Jul 21. Erratum in: Clin Biochem. 2017 Jun;50(9):546. Vourch, P [corrected to Vourc'h , P].

PMID:
27450222
17.

A Multiplatform Metabolomics Approach to Characterize Plasma Levels of Phenylalanine and Tyrosine in Phenylketonuria.

Blasco H, Veyrat-Durebex C, Bertrand M, Patin F, Labarthe F, Henique H, Emond P, Andres CR, Antar C, Landon C, Nadal-Desbarats L, Maillot F.

JIMD Rep. 2017;32:69-79. doi: 10.1007/8904_2016_568. Epub 2016 Jun 15.

18.

Endogenous metabolites that are substrates of organic anion transporter's (OATs) predict methotrexate clearance.

Muhrez K, Benz-de Bretagne I, Nadal-Desbarats L, Blasco H, Gyan E, Choquet S, Montigny F, Emond P, Barin-Le Guellec C.

Pharmacol Res. 2017 Apr;118:121-132. doi: 10.1016/j.phrs.2016.05.021. Epub 2016 May 19.

PMID:
27210722
19.

Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis.

Veyrat-Durebex C, Corcia P, Piver E, Devos D, Dangoumau A, Gouel F, Vourc'h P, Emond P, Laumonnier F, Nadal-Desbarats L, Gordon PH, Andres CR, Blasco H.

Mol Neurobiol. 2016 Dec;53(10):6910-6924. Epub 2015 Dec 14.

PMID:
26666663
20.

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology.

Diémé B, Mavel S, Blasco H, Tripi G, Bonnet-Brilhault F, Malvy J, Bocca C, Andres CR, Nadal-Desbarats L, Emond P.

J Proteome Res. 2015 Dec 4;14(12):5273-82. doi: 10.1021/acs.jproteome.5b00699. Epub 2015 Nov 23.

PMID:
26538324
21.

Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression.

Blasco H, Nadal-Desbarats L, Pradat PF, Gordon PH, Madji Hounoum B, Patin F, Veyrat-Durebex C, Mavel S, Beltran S, Emond P, Andres CR, Corcia P.

Eur J Neurol. 2016 Feb;23(2):346-53. doi: 10.1111/ene.12851. Epub 2015 Oct 28.

PMID:
26508442
22.

Analytical methodology for metabolomics study of adherent mammalian cells using NMR, GC-MS and LC-HRMS.

Madji Hounoum B, Blasco H, Nadal-Desbarats L, Diémé B, Montigny F, Andres CR, Emond P, Mavel S.

Anal Bioanal Chem. 2015 Nov;407(29):8861-72. doi: 10.1007/s00216-015-9047-x. Epub 2015 Oct 7.

PMID:
26446897
23.

Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis.

Tomizza MA, Jessome MA, Barbosa J, Beattie KA, Bensen WG, Bobba RS, Cividino AA, Emond PD, Gordon C, Hart L, Ioannidis G, Koh MX, Larché M, Tavares R, Tytus S, Adachi JD.

J Rheumatol. 2015 Sep;42(9):1582-6. doi: 10.3899/jrheum.141139. Epub 2015 Jul 15.

PMID:
26178277
24.

[Mass spectrometry for steroid assays].

Dufour-Rainfray D, Moal V, Cloix L, Mathieu E, Gauchez AS, Brossaud J, Corcuff JB, Fraissinet F, Collet C, Boux de Casson F, Guilloteau D, Emond P, Reynier P.

Ann Biol Clin (Paris). 2015 Jan-Feb;73(1):70-8. doi: 10.1684/abc.2014.0988. Review. French.

25.

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.

Lepelletier FX, Tauber C, Nicolas C, Solinas M, Castelnau P, Belzung C, Emond P, Cortese S, Faraone SV, Chalon S, Galineau L.

Int J Neuropsychopharmacol. 2014 Oct 31;18(4). pii: pyu044. doi: 10.1093/ijnp/pyu044.

26.

Comparative analysis of targeted metabolomics: dominance-based rough set approach versus orthogonal partial least square-discriminant analysis.

Blasco H, Błaszczyński J, Billaut JC, Nadal-Desbarats L, Pradat PF, Devos D, Moreau C, Andres CR, Emond P, Corcia P, Słowiński R.

J Biomed Inform. 2015 Feb;53:291-9. doi: 10.1016/j.jbi.2014.12.001. Epub 2014 Dec 11.

27.

A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM.

Gourand F, Emond P, Bergström JP, Takano A, Gulyás B, Guilloteau D, Barré L, Halldin C.

Nucl Med Biol. 2014 Jul;41(6):501-6. doi: 10.1016/j.nucmedbio.2014.03.022. Epub 2014 Apr 2.

PMID:
24857865
28.

Combined 1H-NMR and 1H-13C HSQC-NMR to improve urinary screening in autism spectrum disorders.

Nadal-Desbarats L, Aïdoud N, Emond P, Blasco H, Filipiak I, Sarda P, Bonnet-Brilhault F, Mavel S, Andres CR.

Analyst. 2014 Jul 7;139(13):3460-8. doi: 10.1039/c4an00552j.

PMID:
24841505
29.

Assessing the metabolic effects of calcineurin inhibitors in renal transplant recipients by urine metabolic profiling.

Diémé B, Halimi JM, Emond P, Büchler M, Nadal-Desbarat L, Blasco H, Le Guellec C.

Transplantation. 2014 Jul 27;98(2):195-201. doi: 10.1097/TP.0000000000000039.

PMID:
24598938
30.

Untargeted 1H-NMR metabolomics in CSF: toward a diagnostic biomarker for motor neuron disease.

Blasco H, Nadal-Desbarats L, Pradat PF, Gordon PH, Antar C, Veyrat-Durebex C, Moreau C, Devos D, Mavel S, Emond P, Andres CR, Corcia P.

Neurology. 2014 Apr 1;82(13):1167-74. doi: 10.1212/WNL.0000000000000274. Epub 2014 Feb 28.

PMID:
24587475
31.

[Investigation of hyperhomocysteinemia].

Veyrat-Durebex C, Blasco H, Crinier J, Vayne C, Emond P, Labarthe F, Andres CR, Maillot F.

Ann Biol Clin (Paris). 2013 Sep-Oct;71(5):517-25. doi: 10.1684/abc.2013.0879. Review. French.

32.

1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

Mavel S, Nadal-Desbarats L, Blasco H, Bonnet-Brilhault F, Barthélémy C, Montigny F, Sarda P, Laumonnier F, Vourc'h P, Andres CR, Emond P.

Talanta. 2013 Sep 30;114:95-102. doi: 10.1016/j.talanta.2013.03.064. Epub 2013 Apr 9.

33.

Metabolomics in cerebrospinal fluid of patients with amyotrophic lateral sclerosis: an untargeted approach via high-resolution mass spectrometry.

Blasco H, Corcia P, Pradat PF, Bocca C, Gordon PH, Veyrat-Durebex C, Mavel S, Nadal-Desbarats L, Moreau C, Devos D, Andres CR, Emond P.

J Proteome Res. 2013 Aug 2;12(8):3746-54. doi: 10.1021/pr400376e. Epub 2013 Jul 16.

PMID:
23859630
34.

GC-MS-based urine metabolic profiling of autism spectrum disorders.

Emond P, Mavel S, Aïdoud N, Nadal-Desbarats L, Montigny F, Bonnet-Brilhault F, Barthélémy C, Merten M, Sarda P, Laumonnier F, Vourc'h P, Blasco H, Andres CR.

Anal Bioanal Chem. 2013 Jun;405(15):5291-300. doi: 10.1007/s00216-013-6934-x. Epub 2013 Apr 10.

35.

Is NMR metabolic profiling of spent embryo culture media useful to assist in vitro human embryo selection?

Nadal-Desbarats L, Veau S, Blasco H, Emond P, Royere D, Andres CR, Guérif F.

MAGMA. 2013 Apr;26(2):193-202. doi: 10.1007/s10334-012-0331-x. Epub 2012 Aug 10.

PMID:
22878530
36.

QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).

Mavel S, Mincheva Z, Méheux N, Carcenac Y, Guilloteau D, Abarbri M, Emond P.

Bioorg Med Chem. 2012 Feb 15;20(4):1388-95. doi: 10.1016/j.bmc.2012.01.014. Epub 2012 Jan 18.

PMID:
22300887
37.

Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates.

Varrone A, Stepanov V, Nakao R, Tóth M, Gulyás B, Emond P, Deloye JB, Vercouillie J, Stabin MG, Jonsson C, Guilloteau D, Halldin C.

J Nucl Med. 2011 Aug;52(8):1313-21. doi: 10.2967/jnumed.111.089953. Epub 2011 Jul 15.

38.

Volume measurement of bone erosions in magnetic resonance images of patients with rheumatoid arthritis.

Emond PD, Inglis D, Choi A, Tricta J, Adachi JD, Gordon CL.

Magn Reson Med. 2012 Mar;67(3):814-23. doi: 10.1002/mrm.23037. Epub 2011 Jun 17.

39.

1H-NMR-based metabolomic profiling of CSF in early amyotrophic lateral sclerosis.

Blasco H, Corcia P, Moreau C, Veau S, Fournier C, Vourc'h P, Emond P, Gordon P, Pradat PF, Praline J, Devos D, Nadal-Desbarats L, Andres CR.

PLoS One. 2010 Oct 8;5(10):e13223. doi: 10.1371/journal.pone.0013223.

40.

3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT).

Kovac M, Mavel S, Deuther-Conrad W, Méheux N, Glöckner J, Wenzel B, Anderluh M, Brust P, Guilloteau D, Emond P.

Bioorg Med Chem. 2010 Nov 1;18(21):7659-67. doi: 10.1016/j.bmc.2010.08.028. Epub 2010 Aug 17.

PMID:
20889347
41.

Trough infliximab concentrations predict efficacy and sustained control of disease activity in rheumatoid arthritis.

Mulleman D, Chu Miow Lin D, Ducourau E, Emond P, Ternant D, Magdelaine-Beuzelin C, Valat JP, Paintaud G, Goupille P.

Ther Drug Monit. 2010 Apr;32(2):232-6. doi: 10.1097/FTD.0b013e3181cc6fef.

PMID:
20216124
42.

Synthesis and in vitro evaluation of fluorinated diphenyloxide derivatives and sulfur analogs as serotonin transporter ligands.

Mavel S, Meheux N, Guilloteau D, Emond P.

Bioorg Med Chem. 2010 Jan 1;18(1):236-41. doi: 10.1016/j.bmc.2009.10.062. Epub 2009 Nov 4.

PMID:
19926484
43.

Quantitative analysis of subchondral sclerosis of the tibia by bone texture parameters in knee radiographs: site-specific relationships with joint space width.

Wong AK, Beattie KA, Emond PD, Inglis D, Duryea J, Doan A, Ioannidis G, Webber CE, O'Neill J, de Beer J, Adachi JD, Papaioannou A.

Osteoarthritis Cartilage. 2009 Nov;17(11):1453-60. doi: 10.1016/j.joca.2009.05.004. Epub 2009 May 18.

44.

The development of EERA: software for assessing rheumatic joint erosions.

Emond PD, Choi A, O'Neill J, Xie J, Adachi R, Gordon CL.

Can Assoc Radiol J. 2009 Apr;60(2):63-8. doi: 10.1016/j.carj.2009.02.007.

45.

Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging.

Mavel S, Vercouillie J, Garreau L, Raguza T, Ravna AW, Chalon S, Guilloteau D, Emond P.

Bioorg Med Chem. 2008 Oct 1;16(19):9050-5. doi: 10.1016/j.bmc.2008.08.002. Epub 2008 Aug 6.

PMID:
18793858
46.

PE2I: a radiopharmaceutical for in vivo exploration of the dopamine transporter.

Emond P, Guilloteau D, Chalon S.

CNS Neurosci Ther. 2008 Spring;14(1):47-64. doi: 10.1111/j.1527-3458.2007.00033.x. Review.

PMID:
18482099
47.

(E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.

Emond P, Mavel S, Zea-Ponce Y, Kassiou M, Garreau L, Bodard S, Drossard ML, Chalon S, Guilloteau D.

Nucl Med Biol. 2007 Nov;34(8):967-71. Epub 2007 Sep 19.

PMID:
17998100
48.

Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter.

Giboureau N, Emond P, Fulton RR, Henderson DJ, Chalon S, Garreau L, Roselt P, Eberl S, Mavel S, Bodard S, Fulham MJ, Guilloteau D, Kassiou M.

Synapse. 2007 Dec;61(12):962-70.

PMID:
17787004
49.

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET.

Vercouillie J, Deuther-Conrad W, Scheunemann M, Emond P, Fischer S, Funke U, Steinbach J, Guilloteau D, Brust P.

Bioorg Med Chem Lett. 2007 Sep 1;17(17):4991-5. Epub 2007 Mar 7.

PMID:
17658253
50.

Whole-body distribution and radiation dosimetry of the dopamine transporter radioligand [(11)C]PE2I in healthy volunteers.

Ribeiro MJ, Ricard M, Lièvre MA, Bourgeois S, Emond P, Gervais P, Dollé F, Syrota A.

Nucl Med Biol. 2007 May;34(4):465-70.

PMID:
17499737

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