Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 6

1.

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

Demont EH, Chung CW, Furze RC, Grandi P, Michon AM, Wellaway C, Barrett N, Bridges AM, Craggs PD, Diallo H, Dixon DP, Douault C, Emmons AJ, Jones EJ, Karamshi BV, Locke K, Mitchell DJ, Mouzon BH, Prinjha RK, Roberts AD, Sheppard RJ, Watson RJ, Bamborough P.

J Med Chem. 2015 Jul 23;58(14):5649-73. doi: 10.1021/acs.jmedchem.5b00772. Epub 2015 Jul 9.

PMID:
26155854
2.

In vitro pharmacological characterization of vilanterol, a novel long-acting β2-adrenoceptor agonist with 24-hour duration of action.

Slack RJ, Barrett VJ, Morrison VS, Sturton RG, Emmons AJ, Ford AJ, Knowles RG.

J Pharmacol Exp Ther. 2013 Jan;344(1):218-30. doi: 10.1124/jpet.112.198481. Epub 2012 Nov 6.

PMID:
23131596
3.

Metabolism and disposition of vilanterol, a long-acting β(2)-adrenoceptor agonist for inhalation use in humans.

Harrell AW, Siederer SK, Bal J, Patel NH, Young GC, Felgate CC, Pearce SJ, Roberts AD, Beaumont C, Emmons AJ, Pereira AI, Kempsford RD.

Drug Metab Dispos. 2013 Jan;41(1):89-100. doi: 10.1124/dmd.112.048603. Epub 2012 Oct 4.

PMID:
23043183
4.

Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug design.

Bellenie BR, Barton NP, Emmons AJ, Heer JP, Salvagno C.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):990-4. doi: 10.1016/j.bmcl.2008.11.064. Epub 2008 Nov 24.

PMID:
19095447
5.

Discovery and optimisation of a potent and selective tertiary sulfonamide oxytocin antagonist.

Barton NP, Bellenie BR, Doran AT, Emmons AJ, Heer JP, Salvagno CM.

Bioorg Med Chem Lett. 2009 Jan 15;19(2):528-32. doi: 10.1016/j.bmcl.2008.11.018. Epub 2008 Nov 12.

PMID:
19081251
6.

Development of an insect-cell-based assay for detection of kinase inhibition using NF-kappaB-inducing kinase as a paradigm.

Hassan NJ, Gul S, Flett F, Hollingsworth E, Dunne AA, Emmons AJ, Hutchinson JP, Hibbs MJ, Dyos S, Kitson JD, Hiley E, Rüdiger M, Tew DG, Powell DJ, Morse MA.

Biochem J. 2009 Apr 1;419(1):65-73. doi: 10.1042/BJ20081646.

PMID:
19061480

Supplemental Content

Loading ...
Support Center