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Items: 14

1.

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.

Guo M, Härtlova A, Gierliński M, Prescott A, Castellvi J, Losa JH, Petersen SK, Wenzel UA, Dill BD, Emmerich CH, Ramon Y Cajal S, Russell DG, Trost M.

EMBO J. 2019 Jun 3;38(11). pii: e100299. doi: 10.15252/embj.2018100299. Epub 2019 Apr 26.

2.

Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.

Strickson S, Emmerich CH, Goh ETH, Zhang J, Kelsall IR, Macartney T, Hastie CJ, Knebel A, Peggie M, Marchesi F, Arthur JSC, Cohen P.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3481-E3489. doi: 10.1073/pnas.1702367114. Epub 2017 Apr 12.

3.

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation.

McGuire VA, Ruiz-Zorrilla Diez T, Emmerich CH, Strickson S, Ritorto MS, Sutavani RV, Weiβ A, Houslay KF, Knebel A, Meakin PJ, Phair IR, Ashford ML, Trost M, Arthur JS.

Sci Rep. 2016 Aug 8;6:31159. doi: 10.1038/srep31159.

4.

Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling.

Emmerich CH, Bakshi S, Kelsall IR, Ortiz-Guerrero J, Shpiro N, Cohen P.

Biochem Biophys Res Commun. 2016 Jun 3;474(3):452-461. doi: 10.1016/j.bbrc.2016.04.141. Epub 2016 Apr 29.

5.

Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting.

Emmerich CH, Cohen P.

Biochem Biophys Res Commun. 2015 Oct 9;466(1):1-14. doi: 10.1016/j.bbrc.2015.08.109. Epub 2015 Aug 29. Review.

6.

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains.

Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, Komander D, Cohen P.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15247-52. doi: 10.1073/pnas.1314715110. Epub 2013 Aug 28.

7.

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.

Strickson S, Campbell DG, Emmerich CH, Knebel A, Plater L, Ritorto MS, Shpiro N, Cohen P.

Biochem J. 2013 May 1;451(3):427-37. doi: 10.1042/BJ20121651.

8.

Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal.

Engels N, Yigit G, Emmerich CH, Czesnik D, Schild D, Wienands J.

Cell Commun Signal. 2012 Apr 3;10:9. doi: 10.1186/1478-811X-10-9.

9.

The emerging role of linear ubiquitination in cell signaling.

Emmerich CH, Schmukle AC, Walczak H.

Sci Signal. 2011 Dec 20;4(204):re5. doi: 10.1126/scisignal.2002187. Review.

PMID:
22375051
10.

Linear ubiquitination prevents inflammation and regulates immune signalling.

Gerlach B, Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas TL, Webb AI, Rickard JA, Anderton H, Wong WW, Nachbur U, Gangoda L, Warnken U, Purcell AW, Silke J, Walczak H.

Nature. 2011 Mar 31;471(7340):591-6. doi: 10.1038/nature09816.

PMID:
21455173
11.

The linear ubiquitin chain assembly complex forms part of the TNF-R1 signalling complex and is required for effective TNF-induced gene induction and prevents TNF-induced apoptosis.

Emmerich CH, Schmukle AC, Haas TL, Gerlach B, Cordier SM, Rieser E, Walczak H.

Adv Exp Med Biol. 2011;691:115-26. doi: 10.1007/978-1-4419-6612-4_12. No abstract available.

PMID:
21153315
12.

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.

Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H.

Mol Cell. 2009 Dec 11;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013.

13.

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.

Brummer T, Larance M, Herrera Abreu MT, Lyons RJ, Timpson P, Emmerich CH, Fleuren ED, Lehrbach GM, Schramek D, Guilhaus M, James DE, Daly RJ.

EMBO J. 2008 Sep 3;27(17):2305-16.

14.

TRAIL signalling: decisions between life and death.

Falschlehner C, Emmerich CH, Gerlach B, Walczak H.

Int J Biochem Cell Biol. 2007;39(7-8):1462-75. Epub 2007 Feb 14. Review.

PMID:
17403612

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