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Items: 17


PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE.

Cell. 2017 Oct 19;171(3):628-641.e26. doi: 10.1016/j.cell.2017.09.044.


Comments on the Review 'Biomarkers in acute kidney injury - pathophysiological basis and clinical performance' Acta Physiol 2017, 219, 556-574: an update on kidney localization of IGFBP7 and TIMP2.

Emlet DR, Wen X, Kellum JA.

Acta Physiol (Oxf). 2018 Feb;222(2). doi: 10.1111/apha.12934. Epub 2017 Aug 30. No abstract available.


Insulin-like growth factor binding protein 7 and tissue inhibitor of metalloproteinases-2: differential expression and secretion in human kidney tubule cells.

Emlet DR, Pastor-Soler N, Marciszyn A, Wen X, Gomez H, Humphries WH 4th, Morrisroe S, Volpe JK, Kellum JA.

Am J Physiol Renal Physiol. 2017 Feb 1;312(2):F284-F296. doi: 10.1152/ajprenal.00271.2016. Epub 2016 Dec 21.


Sepsis-associated AKI: epithelial cell dysfunction.

Emlet DR, Shaw AD, Kellum JA.

Semin Nephrol. 2015 Jan;35(1):85-95. doi: 10.1016/j.semnephrol.2015.01.009. Review.


Targeting a glioblastoma cancer stem-cell population defined by EGF receptor variant III.

Emlet DR, Gupta P, Holgado-Madruga M, Del Vecchio CA, Mitra SS, Han SY, Li G, Jensen KC, Vogel H, Xu LW, Skirboll SS, Wong AJ.

Cancer Res. 2014 Feb 15;74(4):1238-49. doi: 10.1158/0008-5472.CAN-13-1407. Epub 2013 Dec 23.


Antitumor activity of efrapeptins, alone or in combination with 2-deoxyglucose, in breast cancer in vitro and in vivo.

Papathanassiu AE, MacDonald NJ, Emlet DR, Vu HA.

Cell Stress Chaperones. 2011 Mar;16(2):181-93. doi: 10.1007/s12192-010-0231-9. Epub 2010 Oct 7.


HER2 expression as a potential marker for response to therapy targeted to the EGFR.

Emlet DR, Schwartz R, Brown KA, Pollice AA, Smith CA, Shackney SE.

Br J Cancer. 2006 Apr 24;94(8):1144-53.


Expression of constitutively activated EGFRvIII in non-small cell lung cancer.

Okamoto I, Kenyon LC, Emlet DR, Mori T, Sasaki J, Hirosako S, Ichikawa Y, Kishi H, Godwin AK, Yoshioka M, Suga M, Matsumoto M, Wong AJ.

Cancer Sci. 2003 Jan;94(1):50-6.


Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors.

Tsuiki H, Tnani M, Okamoto I, Kenyon LC, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Wong AJ.

Cancer Res. 2003 Jan 1;63(1):250-5.


Elevated JNK activation contributes to the pathogenesis of human brain tumors.

Antonyak MA, Kenyon LC, Godwin AK, James DC, Emlet DR, Okamoto I, Tnani M, Holgado-Madruga M, Moscatello DK, Wong AJ.

Oncogene. 2002 Aug 1;21(33):5038-46.


Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors.

Okamoto I, Tsuiki H, Kenyon LC, Godwin AK, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Guha A, Matsumoto M, Ushio Y, Saya H, Wong AJ.

Am J Pathol. 2002 Feb;160(2):441-7.


Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor.

Moscatello DK, Holgado-Madruga M, Emlet DR, Montgomery RB, Wong AJ.

J Biol Chem. 1998 Jan 2;273(1):200-6.


Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor.

Holgado-Madruga M, Moscatello DK, Emlet DR, Dieterich R, Wong AJ.

Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12419-24.


Subsets of epidermal growth factor receptors during activation and endocytosis.

Emlet DR, Moscatello DK, Ludlow LB, Wong AJ.

J Biol Chem. 1997 Feb 14;272(7):4079-86.


A Grb2-associated docking protein in EGF- and insulin-receptor signalling.

Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ.

Nature. 1996 Feb 8;379(6565):560-4.


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