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Items: 39

1.

TPI-287, a new taxane family member, reduces the brain metastatic colonization of breast cancer cells.

Fitzgerald DP, Emerson DL, Qian Y, Anwar T, Liewehr DJ, Steinberg SM, Silberman S, Palmieri D, Steeg PS.

Mol Cancer Ther. 2012 Sep;11(9):1959-67. doi: 10.1158/1535-7163.MCT-12-0061. Epub 2012 May 23. Erratum in: Mol Cancer Ther. 2013 Feb;12(2):241.

2.

OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models.

Garton AJ, Crew AP, Franklin M, Cooke AR, Wynne GM, Castaldo L, Kahler J, Winski SL, Franks A, Brown EN, Bittner MA, Keily JF, Briner P, Hidden C, Srebernak MC, Pirrit C, O'Connor M, Chan A, Vulevic B, Henninger D, Hart K, Sennello R, Li AH, Zhang T, Richardson F, Emerson DL, Castelhano AL, Arnold LD, Gibson NW.

Cancer Res. 2006 Jan 15;66(2):1015-24.

3.
4.

OSI-211, a novel liposomal topoisomerase I inhibitor, is active in SCID mouse models of human AML and ALL.

Tomkinson B, Bendele R, Giles FJ, Brown E, Gray A, Hart K, LeRay JD, Meyer D, Pelanne M, Emerson DL.

Leuk Res. 2003 Nov;27(11):1039-50.

PMID:
12859997
5.

Biodistribution of NX211, liposomal lurtotecan, in tumor-bearing mice.

Desjardins JP, Abbott EA, Emerson DL, Tomkinson BE, Leray JD, Brown EN, Hamilton M, Dihel L, Ptaszynski M, Bendele RA, Richardson FC.

Anticancer Drugs. 2001 Mar;12(3):235-45.

PMID:
11290871
6.

Antitumor efficacy, pharmacokinetics, and biodistribution of NX 211: a low-clearance liposomal formulation of lurtotecan.

Emerson DL, Bendele R, Brown E, Chiang S, Desjardins JP, Dihel LC, Gill SC, Hamilton M, LeRay JD, Moon-McDermott L, Moynihan K, Richardson FC, Tomkinson B, Luzzio MJ, Baccanari D.

Clin Cancer Res. 2000 Jul;6(7):2903-12.

7.

Liposomal delivery of camptothecins.

Emerson DL.

Pharm Sci Technolo Today. 2000 Jun;3(6):205-209.

PMID:
10840391
8.

Inhibition of establishment of primary and micrometastatic tumors by a urokinase plasminogen activator receptor antagonist.

Ignar DM, Andrews JL, Witherspoon SM, Leray JD, Clay WC, Kilpatrick K, Onori J, Kost T, Emerson DL.

Clin Exp Metastasis. 1998 Jan;16(1):9-20.

PMID:
9502073
9.

Production of a urokinase plasminogen activator-IgG fusion protein (uPA-IgG) in the baculovirus expression system.

Kost TA, Ignar DM, Clay WC, Andrews J, Leray JD, Overton L, Hoffman CR, Kilpatrick KE, Ellis B, Emerson DL.

Gene. 1997 Apr 29;190(1):139-44.

PMID:
9185859
10.

Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis.

Conway JG, Trexler SJ, Wakefield JA, Marron BE, Emerson DL, Bickett DM, Deaton DN, Garrison D, Elder M, McElroy A, Willmott N, Dockerty AJ, McGeehan GM.

Clin Exp Metastasis. 1996 Mar;14(2):115-24.

PMID:
8605725
11.

Water soluble inhibitors of topoisomerase I: quaternary salt derivatives of camptothecin.

Lackey K, Sternbach DD, Croom DK, Emerson DL, Evans MG, Leitner PL, Luzzio MJ, McIntyre G, Vuong A, Yates J, Besterman JM.

J Med Chem. 1996 Feb 2;39(3):713-9.

PMID:
8576914
12.

Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918.

Witherspoon SM, Emerson DL, Kerr BM, Lloyd TL, Dalton WS, Wissel PS.

Clin Cancer Res. 1996 Jan;2(1):7-12.

13.

Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs.

Uehling DE, Nanthakumar SS, Croom D, Emerson DL, Leitner PP, Luzzio MJ, McIntyre G, Morton B, Profeta S, Sisco J, et al.

J Med Chem. 1995 Mar 31;38(7):1106-18.

PMID:
7707314
14.

Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I.

Luzzio MJ, Besterman JM, Emerson DL, Evans MG, Lackey K, Leitner PL, McIntyre G, Morton B, Myers PL, Peel M, et al.

J Med Chem. 1995 Feb 3;38(3):395-401.

PMID:
7853331
15.

In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues.

Emerson DL, Besterman JM, Brown HR, Evans MG, Leitner PP, Luzzio MJ, Shaffer JE, Sternbach DD, Uehling D, Vuong A.

Cancer Res. 1995 Feb 1;55(3):603-9.

16.

Reconstituted basement membrane enhances neurite outgrowth in PC12 cells induced by nerve growth factor.

Schwarz MA, Mitchell M, Emerson DL.

Cell Growth Differ. 1990 Jul;1(7):313-8.

17.

Western blot analysis of serum antibody reactivity with human melanoma cell antigens in alopecia areata and vitiligo.

Galbraith GM, Miller D, Emerson DL.

Clin Immunol Immunopathol. 1988 Sep;48(3):317-24.

PMID:
3042212
18.

Alpha 2-HS glycoprotein.

Arnaud P, Miribel L, Emerson DL.

Methods Enzymol. 1988;163:431-41. No abstract available.

PMID:
2467172
19.

Diminished serum Gc (vitamin D-binding protein) levels and increased Gc:G-actin complexes in a hamster model of fulminant hepatic necrosis.

Lee WM, Emerson DL, Young WO, Goldschmidt-Clermont PJ, Jollow DJ, Galbraith RM.

Hepatology. 1987 Sep-Oct;7(5):825-30.

PMID:
3115882
20.

Antibodies to polymerized human serum albumin in acute and chronic liver disease.

Lee WM, McLeod L, Martin K, Emerson DL, Galbraith RM.

Hepatology. 1987 Sep-Oct;7(5):906-12.

PMID:
2820857
21.

Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein).

Young WO, Goldschmidt-Clermont PJ, Emerson DL, Lee WM, Jollow DJ, Galbraith RM.

J Lab Clin Med. 1987 Jul;110(1):83-90.

PMID:
3598340
22.

Qualitative and quantitative studies of Gc (vitamin D-binding protein) in normal subjects and patients with periodontal disease.

Krayer JW, Emerson DL, Goldschmidt-Clermont PJ, Nel AE, Werner PA, Galbraith RM.

J Periodontal Res. 1987 Jul;22(4):259-63. No abstract available.

PMID:
2957481
23.

High levels of group-specific component (vitamin-D-binding protein) in the cerebrospinal fluid of infants aged less than 2 months.

Katikaneni LP, Emerson DL, Goldschmidt-Clermont PJ, Loadholt BC, Levkoff AH, Galbraith RM.

Biol Neonate. 1987;52(5):250-5.

PMID:
3676365
24.

Group-specific component (vitamin D binding protein) prevents the interaction between G-actin and profilin.

Goldschmidt-Clermont PJ, Van Alstyne EL, Day JR, Emerson DL, Nel AE, Lazarchick J, Galbraith RM.

Biochemistry. 1986 Oct 21;25(21):6467-72.

PMID:
3790535
25.

Gc (vitamin D-binding protein) binds the 33.5 K tryptic fragment of actin.

Goldschmidt-Clermont PJ, Allen RC, Nel AE, Emerson DL, Day JR, Galbraith RM.

Life Sci. 1986 Feb 24;38(8):735-42.

PMID:
3951329
26.

Altered configuration of Gc on the plasma membrane of transformed and malignant human B lymphocytes.

Nel AE, Navailles M, Emerson DL, Goldschmidt-Clermont P, Pathak SK, Tsang KY, Galbraith RM.

Clin Immunol Immunopathol. 1985 Nov;37(2):191-202.

PMID:
2994927
27.

Accurate quantitation of native Gc in serum and estimation of endogenous Gc: G-actin complexes by rocket immunoelectrophoresis.

Goldschmidt-Clermont PJ, Galbraith RM, Emerson DL, Werner PA, Nel AE, Lee WM.

Clin Chim Acta. 1985 Jun 14;148(3):173-83.

PMID:
4042352
28.

Distinct sites on the G-actin molecule bind group-specific component and deoxyribonuclease I.

Goldschmidt-Clermont PJ, Galbraith RM, Emerson DL, Marsot F, Nel AE, Arnaud P.

Biochem J. 1985 Jun 1;228(2):471-7.

29.

Decreased serum group-specific component protein levels and complexes with actin in fulminant hepatic necrosis.

Lee WM, Emerson DL, Werner PA, Arnaud P, Goldschmidt-Clermont P, Galbraith RM.

Hepatology. 1985 Mar-Apr;5(2):271-5.

PMID:
4038965
30.

Structural studies of T lymphocyte Fc receptors. Association of Gc protein with IgG binding to Fc gamma.

Petrini M, Galbraith RM, Emerson DL, Nel AE, Arnaud P.

J Biol Chem. 1985 Feb 10;260(3):1804-10.

31.

Presence of Gc (vitamin D-binding protein) and interactions with actin in human placental tissue.

Emerson DL, Werner PA, Cheng MH, Galbraith RM.

Am J Reprod Immunol Microbiol. 1985 Jan;7(1):15-21.

PMID:
4039112
32.

Gc (vitamin D binding protein) binds to cytoplasm of all human lymphocytes and is expressed on B-cell membranes.

Petrini M, Galbraith RM, Werner PA, Emerson DL, Arnaud P.

Clin Immunol Immunopathol. 1984 May;31(2):282-95.

PMID:
6325058
34.

Interaction of alpha 2-HS-glycoprotein with immobilized triazine dyes.

Arnaud P, Emerson DL, Gianazza E.

Biochim Biophys Acta. 1983 Dec 28;749(3):270-5.

PMID:
6661440
35.

Evidence of increased Gc:actin complexes in pregnant serum: a possible result of trophoblast embolism.

Emerson DL, Arnaud P, Galbraith RM.

Am J Reprod Immunol. 1983 Dec;4(4):185-9.

PMID:
6689578
36.

Linkage between surface immunoglobulin and cytoskeleton of B lymphocytes may involve Gc protein.

Petrini M, Emerson DL, Galbraith RM.

Nature. 1983 Nov 3-9;306(5938):73-4.

PMID:
6605483
37.

Preliminary immunologic studies of ciguatera poisoning.

Emerson DL, Galbraith RM, McMillan JP, Higerd TB.

Arch Intern Med. 1983 Oct;143(10):1931-3.

PMID:
6625780
38.

Inhibition of lymphocyte activation by antisera to embryonic antigens shared with human placental trophoblast.

Kantor RR, Galbraith RM, Emerson DL, Galbraith GM.

Am J Reprod Immunol. 1983 Apr-May;3(3):114-8.

PMID:
6223537
39.

Cleavage of purified C3 by immobilized trypsin.

Emerson DL, Galbraith RM.

Clin Chim Acta. 1982 Jul 1;122(2):305-12. No abstract available.

PMID:
7105416

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