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Items: 1 to 50 of 137

1.

Wnt7a and miR-370-3p: new contributors to bladder cancer invasion.

Scheunemann D, Pradhan AK, Das SK, Sarkar D, Emdad L, Fisher PB.

Biotarget. 2018 Sep;2. pii: 14. doi: 10.21037/biotarget.2018.08.02. Epub 2018 Sep 4. No abstract available.

2.

Mechanism of internalization of MDA-7/IL-24 protein and its cognate receptors following ligand-receptor docking.

Pradhan AK, Bhoopathi P, Talukdar S, Das SK, Emdad L, Sarkar D, Ivanov AI, Fisher PB.

Oncotarget. 2019 Aug 20;10(49):5103-5117. doi: 10.18632/oncotarget.27150. eCollection 2019 Aug 20.

3.

Regulation of neuroblastoma migration, invasion, and in vivo metastasis by genetic and pharmacological manipulation of MDA-9/Syntenin.

Bhoopathi P, Pradhan AK, Bacolod MD, Emdad L, Sarkar D, Das SK, Fisher PB.

Oncogene. 2019 Aug 12. doi: 10.1038/s41388-019-0920-5. [Epub ahead of print]

PMID:
31406249
4.

Recent insights into apoptosis and toxic autophagy: The roles of MDA-7/IL-24, a multidimensional anti-cancer therapeutic.

Emdad L, Bhoopathi P, Talukdar S, Pradhan AK, Sarkar D, Wang XY, Das SK, Fisher PB.

Semin Cancer Biol. 2019 Jul 26. pii: S1044-579X(19)30023-9. doi: 10.1016/j.semcancer.2019.07.013. [Epub ahead of print] Review.

PMID:
31356866
5.

MDA-9/Syntenin: An emerging global molecular target regulating cancer invasion and metastasis.

Das SK, Sarkar D, Emdad L, Fisher PB.

Adv Cancer Res. 2019;144:137-191. doi: 10.1016/bs.acr.2019.03.011. Epub 2019 Apr 24.

PMID:
31349898
6.

Suppression of prostate cancer pathogenesis using an MDA-9/Syntenin (SDCBP) PDZ1 small molecule inhibitor.

Das SK, Kegelman TP, Pradhan AK, Shen XN, Bhoopathi P, Talukdar S, Maji S, Sarkar D, Emdad L, Fisher PB.

Mol Cancer Ther. 2019 Jul 25. pii: molcanther.1019.2018. doi: 10.1158/1535-7163.MCT-18-1019. [Epub ahead of print]

PMID:
31345950
7.

Prevention of epithelial to mesenchymal transition in colorectal carcinoma by regulation of the E-cadherin-β-catenin-vinculin axis.

Pal I, Rajesh Y, Banik P, Dey G, Dey KK, Bharti R, Naskar D, Chakraborty S, Ghosh SK, Das SK, Emdad L, Kundu SC, Fisher PB, Mandal M.

Cancer Lett. 2019 Jun 28;452:254-263. doi: 10.1016/j.canlet.2019.03.008. Epub 2019 Mar 21.

PMID:
30904616
8.

MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.

Pradhan AK, Bhoopathi P, Talukdar S, Scheunemann D, Sarkar D, Cavenee WK, Das SK, Emdad L, Fisher PB.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5687-5692. doi: 10.1073/pnas.1819869116. Epub 2019 Mar 6.

9.

Dormancy and cancer stem cells: An enigma for cancer therapeutic targeting.

Talukdar S, Bhoopathi P, Emdad L, Das S, Sarkar D, Fisher PB.

Adv Cancer Res. 2019;141:43-84. doi: 10.1016/bs.acr.2018.12.002. Epub 2019 Jan 16.

PMID:
30691685
10.

Rethinking Glioblastoma Therapy: MDA-9/Syntenin Targeted Small Molecule.

Das SK, Sarkar D, Cavenee WK, Emdad L, Fisher PB.

ACS Chem Neurosci. 2019 Mar 20;10(3):1121-1123. doi: 10.1021/acschemneuro.9b00016. Epub 2019 Jan 25.

PMID:
30681320
11.

Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin.

Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB.

Autophagy. 2018;14(10):1845-1846. doi: 10.1080/15548627.2018.1502564. Epub 2018 Aug 17.

12.

Reply to Yoshida: Delineating critical roles of MDA-9 in protective autophagy-mediated anoikis resistance in human glioma stem cells.

Talukdar S, Das SK, Emdad L, Sarkar D, Cavenee WK, Fisher PB.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7654-E7655. doi: 10.1073/pnas.1811113115. Epub 2018 Aug 7. No abstract available.

13.

Recombinant MDA-7/IL24 Suppresses Prostate Cancer Bone Metastasis through Downregulation of the Akt/Mcl-1 Pathway.

Pradhan AK, Bhoopathi P, Talukdar S, Shen XN, Emdad L, Das SK, Sarkar D, Fisher PB.

Mol Cancer Ther. 2018 Sep;17(9):1951-1960. doi: 10.1158/1535-7163.MCT-17-1002. Epub 2018 Jun 22.

14.

Targeting of EGFR, VEGFR2, and Akt by Engineered Dual Drug Encapsulated Mesoporous Silica-Gold Nanoclusters Sensitizes Tamoxifen-Resistant Breast Cancer.

Kumar BNP, Puvvada N, Rajput S, Sarkar S, Mahto MK, Yallapu MM, Pathak A, Emdad L, Das SK, Reis RL, Kundu SC, Fisher PB, Mandal M.

Mol Pharm. 2018 Jul 2;15(7):2698-2713. doi: 10.1021/acs.molpharmaceut.8b00218. Epub 2018 May 30.

PMID:
29787277
15.

MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells.

Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):5768-5773. doi: 10.1073/pnas.1721650115. Epub 2018 May 14.

16.

The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion.

Das SK, Pradhan AK, Bhoopathi P, Talukdar S, Shen XN, Sarkar D, Emdad L, Fisher PB.

Cancer Res. 2018 Jun 1;78(11):2852-2863. doi: 10.1158/0008-5472.CAN-17-2992. Epub 2018 Mar 23.

17.

Prospects of Gene Therapy to Treat Melanoma.

Menezes ME, Talukdar S, Wechman SL, Das SK, Emdad L, Sarkar D, Fisher PB.

Adv Cancer Res. 2018;138:213-237. doi: 10.1016/bs.acr.2018.02.007. Review.

PMID:
29551128
18.

Role of MDA-7/IL-24 a Multifunction Protein in Human Diseases.

Menezes ME, Bhoopathi P, Pradhan AK, Emdad L, Das SK, Guo C, Wang XY, Sarkar D, Fisher PB.

Adv Cancer Res. 2018;138:143-182. doi: 10.1016/bs.acr.2018.02.005. Epub 2018 Mar 2. Review.

19.

New Insights Into Beclin-1: Evolution and Pan-Malignancy Inhibitor Activity.

Wechman SL, Pradhan AK, DeSalle R, Das SK, Emdad L, Sarkar D, Fisher PB.

Adv Cancer Res. 2018;137:77-114. doi: 10.1016/bs.acr.2017.11.002. Epub 2017 Dec 27.

PMID:
29405978
20.

Bcl-2 Antiapoptotic Family Proteins and Chemoresistance in Cancer.

Maji S, Panda S, Samal SK, Shriwas O, Rath R, Pellecchia M, Emdad L, Das SK, Fisher PB, Dash R.

Adv Cancer Res. 2018;137:37-75. doi: 10.1016/bs.acr.2017.11.001. Epub 2017 Dec 6.

PMID:
29405977
21.

Cancer terminator viruses (CTV): A better solution for viral-based therapy of cancer.

Emdad L, Das SK, Wang XY, Sarkar D, Fisher PB.

J Cell Physiol. 2018 Aug;233(8):5684-5695. doi: 10.1002/jcp.26421. Epub 2018 Feb 27. Review.

22.

The Enigma of miRNA Regulation in Cancer.

Pradhan AK, Emdad L, Das SK, Sarkar D, Fisher PB.

Adv Cancer Res. 2017;135:25-52. doi: 10.1016/bs.acr.2017.06.001. Epub 2017 Aug 7. Review.

PMID:
28882224
23.

HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis.

Nitkiewicz J, Borjabad A, Morgello S, Murray J, Chao W, Emdad L, Fisher PB, Potash MJ, Volsky DJ.

J Neuroinflammation. 2017 Jan 26;14(1):23. doi: 10.1186/s12974-017-0794-9.

24.

Somatostatin receptor targeted liposomes with Diacerein inhibit IL-6 for breast cancer therapy.

Bharti R, Dey G, Banerjee I, Dey KK, Parida S, Kumar BN, Das CK, Pal I, Mukherjee M, Misra M, Pradhan AK, Emdad L, Das SK, Fisher PB, Mandal M.

Cancer Lett. 2017 Mar 1;388:292-302. doi: 10.1016/j.canlet.2016.12.021. Epub 2016 Dec 24.

PMID:
28025102
25.

Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.

Kegelman TP, Wu B, Das SK, Talukdar S, Beckta JM, Hu B, Emdad L, Valerie K, Sarkar D, Furnari FB, Cavenee WK, Wei J, Purves A, De SK, Pellecchia M, Fisher PB.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):370-375. doi: 10.1073/pnas.1616100114. Epub 2016 Dec 23.

26.

mda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis.

Pradhan AK, Talukdar S, Bhoopathi P, Shen XN, Emdad L, Das SK, Sarkar D, Fisher PB.

Cancer Res. 2017 Feb 15;77(4):949-959. doi: 10.1158/0008-5472.CAN-16-1731. Epub 2016 Dec 9.

27.

Astrocyte Elevated Gene-1 Regulates β-Catenin Signaling to Maintain Glioma Stem-like Stemness and Self-Renewal.

Hu B, Emdad L, Kegelman TP, Shen XN, Das SK, Sarkar D, Fisher PB.

Mol Cancer Res. 2017 Feb;15(2):225-233. doi: 10.1158/1541-7786.MCR-16-0239. Epub 2016 Nov 30.

28.

MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer.

Menezes ME, Shen XN, Das SK, Emdad L, Sarkar D, Fisher PB.

Oncotarget. 2016 Dec 6;7(49):80175-80189. doi: 10.18632/oncotarget.13373.

29.

Immune infiltration, glioma stratification, and therapeutic implications.

Bacolod MD, Talukdar S, Emdad L, Das SK, Sarkar D, Wang XY, Barany F, Fisher PB.

Transl Cancer Res. 2016 Oct;5(Suppl 4):S652-S656. doi: 10.21037/tcr.2016.10.69. No abstract available.

30.

Detecting Tumor Metastases: The Road to Therapy Starts Here.

Menezes ME, Das SK, Minn I, Emdad L, Wang XY, Sarkar D, Pomper MG, Fisher PB.

Adv Cancer Res. 2016;132:1-44. doi: 10.1016/bs.acr.2016.07.001. Epub 2016 Aug 17. Review.

31.

Novel function of MDA-9/Syntenin (SDCBP) as a regulator of survival and stemness in glioma stem cells.

Talukdar S, Das SK, Pradhan AK, Emdad L, Shen XN, Windle JJ, Sarkar D, Fisher PB.

Oncotarget. 2016 Aug 23;7(34):54102-54119. doi: 10.18632/oncotarget.10851.

32.

Evolving Strategies for Therapeutically Targeting Cancer Stem Cells.

Talukdar S, Emdad L, Das SK, Sarkar D, Fisher PB.

Adv Cancer Res. 2016;131:159-91. doi: 10.1016/bs.acr.2016.04.003. Epub 2016 Jun 3. Review.

PMID:
27451127
33.

AEG-1/MTDH/LYRIC: A Promiscuous Protein Partner Critical in Cancer, Obesity, and CNS Diseases.

Emdad L, Das SK, Hu B, Kegelman T, Kang DC, Lee SG, Sarkar D, Fisher PB.

Adv Cancer Res. 2016;131:97-132. doi: 10.1016/bs.acr.2016.05.002. Epub 2016 Jun 17. Review.

PMID:
27451125
34.

Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.

Das SK, Guo C, Pradhan AK, Bhoopathi P, Talukdar S, Shen XN, Emdad L, Subler MA, Windle JJ, Sarkar D, Wang XY, Fisher PB.

Oncotarget. 2016 Jul 26;7(30):46848-46861. doi: 10.18632/oncotarget.10040.

35.

AEG-1-AKT2: A novel complex controlling the aggressiveness of glioblastoma.

Emdad L, Hu B, Das SK, Sarkar D, Fisher PB.

Mol Cell Oncol. 2015 Jan 23;2(3):e995008. doi: 10.4161/23723556.2014.995008. eCollection 2015 Jul-Sep.

36.

mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.

Bhoopathi P, Lee N, Pradhan AK, Shen XN, Das SK, Sarkar D, Emdad L, Fisher PB.

Cancer Res. 2016 Jun 15;76(12):3572-82. doi: 10.1158/0008-5472.CAN-15-2959. Epub 2016 Apr 13.

37.

Novel therapy of prostate cancer employing a combination of viral-based immunotherapy and a small molecule BH3 mimetic.

Sarkar S, Pradhan A, Das SK, Emdad L, Sarkar D, Pellecchia M, Fisher PB.

Oncoimmunology. 2015 Sep 4;5(3):e1078059. eCollection 2016 Mar.

38.

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine.

Quinn BA, Wang S, Barile E, Das SK, Emdad L, Sarkar D, De SK, Morvaridi SK, Stebbins JL, Pandol SJ, Fisher PB, Pellecchia M.

Oncotarget. 2016 Mar 29;7(13):17103-10. doi: 10.18632/oncotarget.7931.

39.

The role of AEG-1 in the development of liver cancer.

Robertson CL, Srivastava J, Rajasekaran D, Gredler R, Akiel MA, Jariwala N, Siddiq A, Emdad L, Fisher PB, Sarkar D.

Hepat Oncol. 2015;2(3):303-312.

40.

MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer.

Menezes ME, Shen XN, Das SK, Emdad L, Guo C, Yuan F, Li YJ, Archer MC, Zacksenhaus E, Windle JJ, Subler MA, Ben-David Y, Sarkar D, Wang XY, Fisher PB.

Oncotarget. 2015 Nov 10;6(35):36928-42. doi: 10.18632/oncotarget.6047.

41.

Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice.

Li YJ, Liu G, Xia L, Xiao X, Liu JC, Menezes ME, Das SK, Emdad L, Sarkar D, Fisher PB, Archer MC, Zacksenhaus E, Ben-David Y.

Oncotarget. 2015 Nov 10;6(35):36943-54. doi: 10.18632/oncotarget.6046.

42.

The Quest for an Effective Treatment for an Intractable Cancer: Established and Novel Therapies for Pancreatic Adenocarcinoma.

Quinn BA, Lee NA, Kegelman TP, Bhoopathi P, Emdad L, Das SK, Pellecchia M, Sarkar D, Fisher PB.

Adv Cancer Res. 2015;127:283-306. doi: 10.1016/bs.acr.2015.04.009. Epub 2015 May 21. Review.

PMID:
26093904
43.

Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets.

Bacolod MD, Das SK, Sokhi UK, Bradley S, Fenstermacher DA, Pellecchia M, Emdad L, Sarkar D, Fisher PB.

Adv Cancer Res. 2015;127:49-121. doi: 10.1016/bs.acr.2015.04.006. Epub 2015 May 23. Review.

44.

Astrocyte Elevated Gene-1 (AEG-1) Regulates Lipid Homeostasis.

Robertson CL, Srivastava J, Siddiq A, Gredler R, Emdad L, Rajasekaran D, Akiel M, Shen XN, Corwin F, Sundaresan G, Zweit J, Croniger C, Gao X, Ghosh S, Hylemon PB, Subler MA, Windle JJ, Fisher PB, Sarkar D.

J Biol Chem. 2015 Jul 17;290(29):18227-36. doi: 10.1074/jbc.M115.661801. Epub 2015 Jun 11.

45.

Pancreatic Cancer Combination Therapy Using a BH3 Mimetic and a Synthetic Tetracycline.

Quinn BA, Dash R, Sarkar S, Azab B, Bhoopathi P, Das SK, Emdad L, Wei J, Pellecchia M, Sarkar D, Fisher PB.

Cancer Res. 2015 Jun 1;75(11):2305-15. doi: 10.1158/0008-5472.CAN-14-3013.

46.

Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC).

Srivastava J, Robertson CL, Gredler R, Siddiq A, Rajasekaran D, Akiel MA, Emdad L, Mas V, Mukhopadhyay ND, Fisher PB, Sarkar D.

J Biol Chem. 2015 Jun 19;290(25):15549-58. doi: 10.1074/jbc.M115.649707. Epub 2015 May 5.

47.

Therapy of prostate cancer using a novel cancer terminator virus and a small molecule BH-3 mimetic.

Sarkar S, Quinn BA, Shen XN, Dash R, Das SK, Emdad L, Klibanov AL, Wang XY, Pellecchia M, Sarkar D, Fisher PB.

Oncotarget. 2015 May 10;6(13):10712-27.

48.

Noninvasive approaches for detecting and monitoring bladder cancer.

Talukdar S, Emdad L, Das SK, Sarkar D, Fisher PB.

Expert Rev Anticancer Ther. 2015 Mar;15(3):283-94. doi: 10.1586/14737140.2015.989838. Epub 2014 Dec 10. Review.

PMID:
25494295
49.

Reversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approach.

Sarkar S, Quinn BA, Shen X, Dent P, Das SK, Emdad L, Sarkar D, Fisher PB.

Mol Pharmacol. 2015 Feb;87(2):286-95. doi: 10.1124/mol.114.094375. Epub 2014 Dec 1.

50.

Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review).

Jariwala N, Rajasekaran D, Srivastava J, Gredler R, Akiel MA, Robertson CL, Emdad L, Fisher PB, Sarkar D.

Int J Oncol. 2015 Feb;46(2):465-73. doi: 10.3892/ijo.2014.2766. Epub 2014 Nov 18. Review.

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