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Items: 26

1.

Identification of two microRNA nodes as potential cooperative modulators of liver metabolism.

Hochreuter MY, Altıntaş A, Garde C, Emanuelli B, Kahn CR, Zierath JR, Vienberg S, Barrès R.

Hepatol Res. 2019 Aug 13. doi: 10.1111/hepr.13419. [Epub ahead of print]

PMID:
31408567
2.

Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue.

Lundh M, Petersen PS, Isidor MS, Kazoka-Sørensen DN, Plucińska K, Shamsi F, Ørskov C, Tozzi M, Brown EL, Andersen E, Ma T, Müller U, Barrès R, Kristiansen VB, Gerhart-Hines Z, Tseng YH, Emanuelli B.

EMBO Rep. 2019 Aug;20(8):e48216. doi: 10.15252/embr.201948216. Epub 2019 Jul 2.

PMID:
31264358
3.

The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression.

Wen Q, Xie X, Zhao C, Ren Q, Zhang X, Wei D, Emanuelli B, Du Y.

Sci Total Environ. 2019 Jun 20;670:67-77. doi: 10.1016/j.scitotenv.2019.03.201. Epub 2019 Mar 15.

PMID:
30903904
4.

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.

Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z.

Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31.

5.

Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action.

Rabiee A, Krüger M, Ardenkjær-Larsen J, Kahn CR, Emanuelli B.

Cell Signal. 2018 Jul;47:1-15. doi: 10.1016/j.cellsig.2018.03.003. Epub 2018 Mar 14.

6.

Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA.

Lundh M, Pluciñska K, Isidor MS, Petersen PSS, Emanuelli B.

Mol Metab. 2017 Oct;6(10):1313-1320. doi: 10.1016/j.molmet.2017.07.001. Epub 2017 Jul 8.

7.

Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5).

Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR.

J Biol Chem. 2016 Aug 5;291(32):16878. doi: 10.1074/jbc.A111.337048. No abstract available.

8.

Interplay between FGF21 and insulin action in the liver regulates metabolism.

Emanuelli B, Vienberg SG, Smyth G, Cheng C, Stanford KI, Arumugam M, Michael MD, Adams AC, Kharitonenkov A, Kahn CR.

J Clin Invest. 2015 Jan;125(1):458. doi: 10.1172/JCI80223. Epub 2015 Jan 2. No abstract available.

9.

Interplay between FGF21 and insulin action in the liver regulates metabolism.

Emanuelli B, Vienberg SG, Smyth G, Cheng C, Stanford KI, Arumugam M, Michael MD, Adams AC, Kharitonenkov A, Kahn CR.

J Clin Invest. 2014 Feb;124(2):515-27. doi: 10.1172/JCI67353. Epub 2014 Jan 9. Erratum in: J Clin Invest. 2015 Jan;125(1):458.

10.

Rest energy expenditure in Parkinson's disease: role of disease progression and dopaminergic therapy.

Capecci M, Petrelli M, Emanuelli B, Millevolte M, Nicolai A, Provinciali L, Ceravolo MG.

Parkinsonism Relat Disord. 2013 Feb;19(2):238-41. doi: 10.1016/j.parkreldis.2012.10.016. Epub 2012 Nov 20.

PMID:
23182312
11.

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.

Vernochet C, Mourier A, Bezy O, Macotela Y, Boucher J, Rardin MJ, An D, Lee KY, Ilkayeva OR, Zingaretti CM, Emanuelli B, Smyth G, Cinti S, Newgard CB, Gibson BW, Larsson NG, Kahn CR.

Cell Metab. 2012 Dec 5;16(6):765-76. doi: 10.1016/j.cmet.2012.10.016. Epub 2012 Nov 15.

12.

Intrinsic differences in adipocyte precursor cells from different white fat depots.

Macotela Y, Emanuelli B, Mori MA, Gesta S, Schulz TJ, Tseng YH, Kahn CR.

Diabetes. 2012 Jul;61(7):1691-9. doi: 10.2337/db11-1753. Epub 2012 May 17.

13.

Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).

Palsgaard J, Emanuelli B, Winnay JN, Sumara G, Karsenty G, Kahn CR.

J Biol Chem. 2012 Apr 6;287(15):12016-26. doi: 10.1074/jbc.M111.337048. Epub 2012 Feb 15. Erratum in: J Biol Chem. 2016 Aug 5;291(32):16878.

14.

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.

Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR.

Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14608-13. doi: 10.1073/pnas.1111308108. Epub 2011 Aug 22.

15.

Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.

Macotela Y, Emanuelli B, Bång AM, Espinoza DO, Boucher J, Beebe K, Gall W, Kahn CR.

PLoS One. 2011;6(6):e21187. doi: 10.1371/journal.pone.0021187. Epub 2011 Jun 22.

16.

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.

Bezy O, Tran TT, Pihlajamäki J, Suzuki R, Emanuelli B, Winnay J, Mori MA, Haas J, Biddinger SB, Leitges M, Goldfine AB, Patti ME, King GL, Kahn CR.

J Clin Invest. 2011 Jun;121(6):2504-17. doi: 10.1172/JCI46045. Epub 2011 May 16.

17.

Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis.

Zhang H, Schulz TJ, Espinoza DO, Huang TL, Emanuelli B, Kristiansen K, Tseng YH.

Mol Cell Biol. 2010 Sep;30(17):4224-33. doi: 10.1128/MCB.00363-10. Epub 2010 Jun 28.

18.

SOCS-1 deficiency does not prevent diet-induced insulin resistance.

Emanuelli B, Macotela Y, Boucher J, Ronald Kahn C.

Biochem Biophys Res Commun. 2008 Dec 12;377(2):447-452. doi: 10.1016/j.bbrc.2008.09.158. Epub 2008 Oct 16.

19.

Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance.

Emanuelli B, Eberlé D, Suzuki R, Kahn CR.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3545-50. doi: 10.1073/pnas.0712275105. Epub 2008 Feb 22.

20.

Critical nodes in signalling pathways: insights into insulin action.

Taniguchi CM, Emanuelli B, Kahn CR.

Nat Rev Mol Cell Biol. 2006 Feb;7(2):85-96. Review.

PMID:
16493415
21.

The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells.

Emanuelli B, Glondu M, Filloux C, Peraldi P, Van Obberghen E.

Diabetes. 2004 Dec;53 Suppl 3:S97-S103.

22.

Surfing the insulin signaling web.

Van Obberghen E, Baron V, Delahaye L, Emanuelli B, Filippa N, Giorgetti-Peraldi S, Lebrun P, Mothe-Satney I, Peraldi P, Rocchi S, Sawka-Verhelle D, Tartare-Deckert S, Giudicelli J.

Eur J Clin Invest. 2001 Nov;31(11):966-77. Review.

PMID:
11737239
23.

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

Emanuelli B, Peraldi P, Filloux C, Chavey C, Freidinger K, Hilton DJ, Hotamisligil GS, Van Obberghen E.

J Biol Chem. 2001 Dec 21;276(51):47944-9. Epub 2001 Oct 16.

24.

Insulin induces suppressor of cytokine signaling-3 tyrosine phosphorylation through janus-activated kinase.

Peraldi P, Filloux C, Emanuelli B, Hilton DJ, Van Obberghen E.

J Biol Chem. 2001 Jul 6;276(27):24614-20. Epub 2001 Apr 26.

25.

SOCS-3 is an insulin-induced negative regulator of insulin signaling.

Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E.

J Biol Chem. 2000 May 26;275(21):15985-91.

26.

HIV type 1 intraperitoneal infection of rabbits permits early detection of serum antibodies to Gag, Pol, and Env proteins, neutralizing antibodies, and proviral DNA from peripheral blood mononuclear cells.

Debiaggi M, Bruno R, Carlevari M, Achilli G, Emanuelli B, Cereda PM, Romero E, Filice G.

AIDS Res Hum Retroviruses. 1995 Feb;11(2):287-96.

PMID:
7742042

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