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Protein synthesis rates of muscle, tendon, ligament, cartilage, and bone tissue in vivo in humans.

Smeets JSJ, Horstman AMH, Vles GF, Emans PJ, Goessens JPB, Gijsen AP, van Kranenburg JMX, van Loon LJC.

PLoS One. 2019 Nov 7;14(11):e0224745. doi: 10.1371/journal.pone.0224745. eCollection 2019.


Spatially resolved endogenous improved metabolite detection in human osteoarthritis cartilage by matrix assisted laser desorption ionization mass spectrometry imaging.

Eveque-Mourroux MR, Emans PJ, Zautsen RRM, Boonen A, Heeren RMA, Cillero-Pastor B.

Analyst. 2019 Oct 21;144(20):5953-5958. doi: 10.1039/c9an00944b. Epub 2019 Aug 16.


Local controlled release of corticosteroids extends surgically induced joint instability by inhibiting tissue healing.

Rudnik-Jansen I, Tellegen AR, Pouran B, Schrijver K, Meij BP, Emans PJ, de Gendt E, Thomas RE, Kik MJL, de Visser HM, Weinans H, Egas A, van Maarseveen E, Woike N, Mihov G, Thies J, Tryfonidou MA, Creemers LB.

Br J Pharmacol. 2019 Oct;176(20):4050-4064. doi: 10.1111/bph.14817. Epub 2019 Oct 8.


Knee adduction moments are not increased in obese knee osteoarthritis patients during stair negotiation.

Verlaan L, Boekesteijn RJ, Oomen PW, Liu WY, Peters MJM, Emans PJ, van Rhijn LW, Meijer K.

Gait Posture. 2019 Sep;73:154-160. doi: 10.1016/j.gaitpost.2019.07.192. Epub 2019 Jul 16.


The Modified Hedgehog Technique to Repair Pure Chondral Shear-off Lesions in the Pediatric Knee.

Jeuken RM, Vles GF, Jansen EJP, Loeffen D, Emans PJ.

Cartilage. 2019 Jun 19:1947603519855762. doi: 10.1177/1947603519855762. [Epub ahead of print]


Protein Intake Falls below 0.6 g•kg-1•d-1 in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty.

Weijzen MEG, Kouw IWK, Verschuren AAJ, Muyters R, Geurts JA, Emans PJ, Geerlings P, Verdijk LB, van Loon LJC.

J Nutr Health Aging. 2019;23(3):299-305. doi: /10.1007/s12603-019-1157-2.


Knee Joint Distraction Compared with High Tibial Osteotomy and Total Knee Arthroplasty: Two-Year Clinical, Radiographic, and Biochemical Marker Outcomes of Two Randomized Controlled Trials.

Jansen MP, Besselink NJ, van Heerwaarden RJ, Custers RJH, Emans PJ, Spruijt S, Mastbergen SC, Lafeber FPJG.

Cartilage. 2019 Feb 13:1947603519828432. doi: 10.1177/1947603519828432. [Epub ahead of print]


Biomechanical Alterations during Sit-to-Stand Transfer Are Caused by a Synergy between Knee Osteoarthritis and Obesity.

Verlaan L, Boekesteijn RJ, Oomen PW, Liu WY, Peters MJM, Witlox MA, Emans PJ, van Rhijn LW, Meijer K.

Biomed Res Int. 2018 Dec 9;2018:3519498. doi: 10.1155/2018/3519498. eCollection 2018.


Prevalence and development of hip and knee osteoarthritis according to American College of Rheumatology criteria in the CHECK cohort.

Damen J, van Rijn RM, Emans PJ, Hilberdink WKHA, Wesseling J, Oei EHG, Bierma-Zeinstra SMA.

Arthritis Res Ther. 2019 Jan 5;21(1):4. doi: 10.1186/s13075-018-1785-7.


Limited predictive value of pre-surgical level of functioning for functioning at 3 and 12 months after TKA.

Berghmans DDP, Lenssen AF, Emans PJ, van Rhijn LW, de Bie RA.

Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1651-1657. doi: 10.1007/s00167-018-5288-5. Epub 2018 Nov 28.


Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study.

Denissen KFM, Boonen A, Nielen JTH, Feitsma AL, van den Heuvel EGHM, Emans PJ, Stehouwer CDA, Sep SJS, van Dongen MCJM, Dagnelie PC, Eussen SJPM.

Eur J Nutr. 2019 Oct;58(7):2693-2704. doi: 10.1007/s00394-018-1818-7. Epub 2018 Sep 21.


Functions, disabilities and perceived health in the first year after total knee arthroplasty; a prospective cohort study.

Berghmans DDP, Lenssen AF, Emans PJ, de Bie RA.

BMC Musculoskelet Disord. 2018 Jul 25;19(1):250. doi: 10.1186/s12891-018-2159-7.


Controlled release of celecoxib inhibits inflammation, bone cysts and osteophyte formation in a preclinical model of osteoarthritis.

Tellegen AR, Rudnik-Jansen I, Pouran B, de Visser HM, Weinans HH, Thomas RE, Kik MJL, Grinwis GCM, Thies JC, Woike N, Mihov G, Emans PJ, Meij BP, Creemers LB, Tryfonidou MA.

Drug Deliv. 2018 Nov;25(1):1438-1447. doi: 10.1080/10717544.2018.1482971.


Celecoxib-mediated reduction of prostanoid release in Hoffa's fat pad from donors with cartilage pathology results in an attenuated inflammatory phenotype.

Timur UT, Caron MMJ, Bastiaansen-Jenniskens YM, Welting TJM, van Rhijn LW, van Osch GJVM, Emans PJ.

Osteoarthritis Cartilage. 2018 May;26(5):697-706. doi: 10.1016/j.joca.2018.01.025. Epub 2018 Feb 7.


Association of type 2 diabetes mellitus with self-reported knee pain and clinical knee osteoarthritis: The Maastricht Study.

Nielen JTH, Emans PJ, van den Bemt B, Dagnelie PC, Schram MT, Stehouwer CDA, Schaper NC, Denissen KFM, de Vries F, Boonen A.

Diabetes Metab. 2018 Jun;44(3):296-299. doi: 10.1016/j.diabet.2018.01.013. Epub 2018 Feb 3. No abstract available.


Patient-specific instrumentation in Oxford unicompartmental knee arthroplasty is reliable and accurate except for the tibial rotation.

Kerens B, Leenders AM, Schotanus MGM, Boonen B, Tuinebreijer WE, Emans PJ, Jong B, Kort NP.

Knee Surg Sports Traumatol Arthrosc. 2018 Jun;26(6):1823-1830. doi: 10.1007/s00167-017-4826-x. Epub 2017 Dec 27.


Disease burden of knee osteoarthritis patients with a joint replacement compared to matched controls: a population-based analysis of a Dutch medical claims database.

Nielen JTH, Boonen A, Dagnelie PC, van den Bemt BJF, Emans PJ, Lafeber FPJG, van Spil WE, de Vries F, Welsing PMJ.

Osteoarthritis Cartilage. 2018 Feb;26(2):202-210. doi: 10.1016/j.joca.2017.11.012. Epub 2017 Dec 2.


Impairment of the chondrogenic phase of endochondral ossification in vivo by inhibition of cyclooxygenase-2.

Janssen MP, Caron MM, van Rietbergen B, Surtel DA, van Rhijn LW, Welting TJ, Emans PJ.

Eur Cell Mater. 2017 Oct 17;34:202-216. doi: 10.22203/eCM.v034a13.


Accuracy of the Precision Saw versus the Sagittal Saw during total knee arthroplasty: A randomised clinical trial.

Feczko PZ, Fokkenrood HJP, van Assen T, Deckers P, Emans PJ, Arts JJ.

Knee. 2017 Oct;24(5):1213-1220. doi: 10.1016/j.knee.2017.07.018. Epub 2017 Aug 16.


Measurement of lower limb alignment: there are within-person differences between weight-bearing and non-weight-bearing measurement modalities.

Schoenmakers DAL, Feczko PZ, Boonen B, Schotanus MGM, Kort NP, Emans PJ.

Knee Surg Sports Traumatol Arthrosc. 2017 Nov;25(11):3569-3575. doi: 10.1007/s00167-017-4636-1. Epub 2017 Jul 18.


Comparison of fixed and mobile-bearing total knee arthroplasty in terms of patellofemoral pain and function: a prospective, randomised, controlled trial.

Feczko PZ, Jutten LM, van Steyn MJ, Deckers P, Emans PJ, Arts JJ.

BMC Musculoskelet Disord. 2017 Jun 29;18(1):279. doi: 10.1186/s12891-017-1635-9.


Knee joint distraction compared with total knee arthroplasty: a randomised controlled trial.

van der Woude JA, Wiegant K, van Heerwaarden RJ, Spruijt S, Emans PJ, Mastbergen SC, Lafeber FP.

Bone Joint J. 2017 Jan;99-B(1):51-58. doi: 10.1302/0301-620X.99B1.BJJ-2016-0099.R3.


Celecoxib-loaded PEA microspheres as an auto regulatory drug-delivery system after intra-articular injection.

Janssen M, Timur UT, Woike N, Welting TJ, Draaisma G, Gijbels M, van Rhijn LW, Mihov G, Thies J, Emans PJ.

J Control Release. 2016 Dec 28;244(Pt A):30-40. doi: 10.1016/j.jconrel.2016.11.003. Epub 2016 Nov 8.


Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements.

Nielen JT, Dagnelie PC, Emans PJ, Veldhorst-Janssen N, Lalmohamed A, van Staa TP, Boonen AE, van den Bemt BJ, de Vries F.

Pharmacoepidemiol Drug Saf. 2016 Nov;25(11):1245-1252. doi: 10.1002/pds.4089. Epub 2016 Sep 4.


Noise Exposure in TKA Surgery; Oscillating Tip Saw Systems vs Oscillating Blade Saw Systems.

Peters MP, Feczko PZ, Tsang K, van Rietbergen B, Arts JJ, Emans PJ.

J Arthroplasty. 2016 Dec;31(12):2773-2777. doi: 10.1016/j.arth.2016.05.030. Epub 2016 May 27.


[Pain trajectories in early symptomatic knee osteoarthritis].

Bastick AN, Wesseling J, Damen J, Verkleij SP, Emans PJ, Bindels PJ, Bierma-Zeinstra SM.

Ned Tijdschr Geneeskd. 2016;160:D449. Dutch.


Indomethacin induces differential effects on in vitro endochondral ossification depending on the chondrocyte's differentiation stage.

Caron MMJ, Emans PJ, Cremers A, Surtel DAM, van Rhijn LW, Welting TJM.

J Orthop Res. 2017 Apr;35(4):847-857. doi: 10.1002/jor.23324. Epub 2016 Jun 22.


Polymers in Cartilage Defect Repair of the Knee: Current Status and Future Prospects.

Jeuken RM, Roth AK, Peters RJRW, Van Donkelaar CC, Thies JC, Van Rhijn LW, Emans PJ.

Polymers (Basel). 2016 Jun 4;8(6). pii: E219. doi: 10.3390/polym8060219. Review.


Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study.

Nielen JT, Emans PJ, Dagnelie PC, Boonen A, Lalmohamed A, de Boer A, van den Bemt BJ, de Vries F.

Medicine (Baltimore). 2016 May;95(20):e3739. doi: 10.1097/MD.0000000000003739.


Cementless versus cemented Oxford unicompartmental knee arthroplasty: early results of a non-designer user group.

Kerens B, Schotanus MGM, Boonen B, Boog P, Emans PJ, Lacroix H, Kort NP.

Knee Surg Sports Traumatol Arthrosc. 2017 Mar;25(3):703-709. doi: 10.1007/s00167-016-4149-3. Epub 2016 May 9.


The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells.

Caron MM, Emans PJ, Sanen K, Surtel DA, Cremers A, Ophelders D, van Rhijn LW, Welting TJ.

PLoS One. 2016 Apr 6;11(4):e0153162. doi: 10.1371/journal.pone.0153162. eCollection 2016.


Effect of aqua-cycling on pain and physical functioning compared with usual care in patients with knee osteoarthritis: study protocol of a randomised controlled trial.

Rewald S, Mesters I, Lenssen AF, Emans PJ, Wijnen W, de Bie RA.

BMC Musculoskelet Disord. 2016 Feb 18;17:88. doi: 10.1186/s12891-016-0939-5.


Tibial component rotation in total knee arthroplasty.

Feczko PZ, Pijls BG, van Steijn MJ, van Rhijn LW, Arts JJ, Emans PJ.

BMC Musculoskelet Disord. 2016 Feb 16;17:87. doi: 10.1186/s12891-016-0940-z.


Defining knee pain trajectories in early symptomatic knee osteoarthritis in primary care: 5-year results from a nationwide prospective cohort study (CHECK).

Bastick AN, Wesseling J, Damen J, Verkleij SP, Emans PJ, Bindels PJ, Bierma-Zeinstra SM.

Br J Gen Pract. 2016 Jan;66(642):e32-9. doi: 10.3399/bjgp15X688129. Epub 2015 Dec 6.


Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink.

Nielen JT, van den Bemt BJ, Boonen A, Dagnelie PC, Emans PJ, Veldhorst N, Lalmohamed A, van Staa TP, de Vries F.

BMJ Open. 2015 Nov 30;5(11):e009017. doi: 10.1136/bmjopen-2015-009017.


Prevalence and Predictive Factors of Chronic Postsurgical Pain and Global Surgical Recovery 1 Year After Outpatient Knee Arthroscopy: A Prospective Cohort Study.

Hoofwijk DM, Fiddelers AA, Emans PJ, Joosten EA, Gramke HF, Marcus MA, Buhre WF.

Medicine (Baltimore). 2015 Nov;94(45):e2017. doi: 10.1097/MD.0000000000002017.


Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study.

Nielen JT, de Vries F, Dagnelie PC, van den Bemt BJ, Emans PJ, Lalmohamed A, de Boer A, Boonen A.

Br J Clin Pharmacol. 2016 Feb;81(2):370-8. doi: 10.1111/bcp.12786. Epub 2015 Nov 4.


BAPX-1/NKX-3.2 acts as a chondrocyte hypertrophy molecular switch in osteoarthritis.

Caron MM, Emans PJ, Surtel DA, van der Kraan PM, van Rhijn LW, Welting TJ.

Arthritis Rheumatol. 2015 Nov;67(11):2944-56. doi: 10.1002/art.39293.


Validation of statistical shape modelling to predict hip osteoarthritis in females: data from two prospective cohort studies (Cohort Hip and Cohort Knee and Chingford).

Agricola R, Leyland KM, Bierma-Zeinstra SM, Thomas GE, Emans PJ, Spector TD, Weinans H, Waarsing JH, Arden NK.

Rheumatology (Oxford). 2015 Nov;54(11):2033-41. doi: 10.1093/rheumatology/kev232. Epub 2015 Jul 1.


Safety and performance of Hydros and Hydros-TA for knee osteoarthritis: a prospective, multicenter, randomized, double-blind feasibility trial.

Petrella RJ, Emans PJ, Alleyne J, Dellaert F, Gill DP, Maroney M.

BMC Musculoskelet Disord. 2015 Mar 18;16:57. doi: 10.1186/s12891-015-0513-6.


Aquatic circuit training including aqua-cycling in patients with knee osteoarthritis: A feasibility study.

Rewald S, Mesters I, Emans PJ, Arts JJ, Lenssen AF, de Bie RA.

J Rehabil Med. 2015 Apr;47(4):376-81. doi: 10.2340/16501977-1937.


Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: data from CHECK, a cohort of early-osteoarthritis subjects.

Van Spil WE, Nair SC, Kinds MB, Emans PJ, Hilberdink WK, Welsing PM, Lafeber FP.

Osteoarthritis Cartilage. 2015 Jan;23(1):48-56. doi: 10.1016/j.joca.2014.09.003. Epub 2014 Sep 6.


Calcium phosphate based three-dimensional cold plotted bone scaffolds for critical size bone defects.

Bergmann CJ, Odekerken JC, Welting TJ, Jungwirth F, Devine D, Bouré L, Zeiter S, van Rhijn LW, Telle R, Fischer H, Emans PJ.

Biomed Res Int. 2014;2014:852610. doi: 10.1155/2014/852610. Epub 2014 Feb 26.


Revision from unicompartmental to total knee replacement: the clinical outcome depends on reason for revision.

Kerens B, Boonen B, Schotanus MG, Lacroix H, Emans PJ, Kort NP.

Bone Joint J. 2013 Sep;95-B(9):1204-8. doi: 10.1302/0301-620X.95B9.31085.


NSAIDs and fracture healing.

Geusens P, Emans PJ, de Jong JJ, van den Bergh J.

Curr Opin Rheumatol. 2013 Jul;25(4):524-31. doi: 10.1097/BOR.0b013e32836200b8. Review.


Identifying phenotypes of knee osteoarthritis by separate quantitative radiographic features may improve patient selection for more targeted treatment.

Kinds MB, Marijnissen AC, Viergever MA, Emans PJ, Lafeber FP, Welsing PM.

J Rheumatol. 2013 Jun;40(6):891-902. doi: 10.3899/jrheum.121004. Epub 2013 May 1.


Randomized comparison between the cemented Scientific Hip Prosthesis and Omnifit: 2-year DEXA and minimum 10-year clinical follow-up.

Broeke RH, Harings SE, Emans PJ, Jutten LM, Kessels AG, Geesink RG.

J Arthroplasty. 2013 Sep;28(8):1354-61. doi: 10.1016/j.arth.2012.09.024. Epub 2013 Feb 27.


Hypertrophic differentiation during chondrogenic differentiation of progenitor cells is stimulated by BMP-2 but suppressed by BMP-7.

Caron MM, Emans PJ, Cremers A, Surtel DA, Coolsen MM, van Rhijn LW, Welting TJ.

Osteoarthritis Cartilage. 2013 Apr;21(4):604-13. doi: 10.1016/j.joca.2013.01.009. Epub 2013 Jan 24.


Osmolarity determines the in vitro chondrogenic differentiation capacity of progenitor cells via nuclear factor of activated T-cells 5.

Caron MM, van der Windt AE, Emans PJ, van Rhijn LW, Jahr H, Welting TJ.

Bone. 2013 Mar;53(1):94-102. doi: 10.1016/j.bone.2012.11.032. Epub 2012 Dec 4.


Alterations to the subchondral bone architecture during osteoarthritis: bone adaptation vs endochondral bone formation.

Cox LG, van Donkelaar CC, van Rietbergen B, Emans PJ, Ito K.

Osteoarthritis Cartilage. 2013 Feb;21(2):331-8. doi: 10.1016/j.joca.2012.10.013. Epub 2012 Nov 7.

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