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Items: 1 to 50 of 281

1.

Regulation of the ERK signalling pathway in the developing mouse blastocyst.

Azami T, Bassalert C, Allègre N, Valverde Estrella L, Pouchin P, Ema M, Chazaud C.

Development. 2019 Jul 25;146(14). pii: dev177139. doi: 10.1242/dev.177139.

PMID:
31320324
2.

Generation of bicistronic reporter knockin mice for visualizing germ layers.

Suzuki H, Dinh TTH, Daitoku Y, Tanimoto Y, Kato K, Azami T, Ema M, Murata K, Mizuno S, Sugiyama F.

Exp Anim. 2019 Jun 13. doi: 10.1538/expanim.19-0031. [Epub ahead of print]

3.

Interaction of the nervous system and vascular system is required for the proper assembly of the neocortex.

Takashima S, Watanabe C, Ema M, Mizutani KI.

Neurochem Int. 2019 Oct;129:104481. doi: 10.1016/j.neuint.2019.104481. Epub 2019 May 29.

PMID:
31150772
4.

Highly efficient induction of primate iPS cells by combining RNA transfection and chemical compounds.

Watanabe T, Yamazaki S, Yoneda N, Shinohara H, Tomioka I, Higuchi Y, Yagoto M, Ema M, Suemizu H, Kawai K, Sasaki E.

Genes Cells. 2019 Jul;24(7):473-484. doi: 10.1111/gtc.12702. Epub 2019 Jun 17.

PMID:
31099158
5.

Generation of an OCT3/4 reporter cynomolgus monkey ES cell line using CRISPR/Cas9.

Kobayashi K, Tsukiyama T, Nakaya M, Kageyama S, Tomita K, Murai R, Yoshida T, Narita M, Kawauchi A, Ema M.

Stem Cell Res. 2019 May;37:101439. doi: 10.1016/j.scr.2019.101439. Epub 2019 Apr 15.

6.

Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†.

Seita Y, Tsukiyama T, Azami T, Kobayashi K, Iwatani C, Tsuchiya H, Nakaya M, Tanabe H, Hitoshi S, Miyoshi H, Nakamura S, Kawauchi A, Ema M.

Biol Reprod. 2019 Jun 1;100(6):1440-1452. doi: 10.1093/biolre/ioz040.

PMID:
30869744
7.

Poor second ovarian stimulation in cynomolgus monkeys (Macaca fascicularis) is associated with the production of antibodies against human follicle-stimulating hormone.

Seita Y, Iwatani C, Tsuchiya H, Nakamura S, Kimura F, Murakami T, Ema M.

J Reprod Dev. 2019 Jun 14;65(3):267-273. doi: 10.1262/jrd.2018-156. Epub 2019 Mar 7.

8.

Oxidized unsaturated fatty acids induce apoptotic cell death in cultured cells.

Iuchi K, Ema M, Suzuki M, Yokoyama C, Hisatomi H.

Mol Med Rep. 2019 Apr;19(4):2767-2773. doi: 10.3892/mmr.2019.9940. Epub 2019 Feb 5.

9.

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells.

Watanabe C, Matsushita J, Azami T, Tsukiyama-Fujii S, Tsukiyama T, Mizuno S, Takahashi S, Ema M.

PLoS One. 2019 Jan 2;14(1):e0210060. doi: 10.1371/journal.pone.0210060. eCollection 2019.

10.

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche.

Kitadate Y, Jörg DJ, Tokue M, Maruyama A, Ichikawa R, Tsuchiya S, Segi-Nishida E, Nakagawa T, Uchida A, Kimura-Yoshida C, Mizuno S, Sugiyama F, Azami T, Ema M, Noda C, Kobayashi S, Matsuo I, Kanai Y, Nagasawa T, Sugimoto Y, Takahashi S, Simons BD, Yoshida S.

Cell Stem Cell. 2019 Jan 3;24(1):79-92.e6. doi: 10.1016/j.stem.2018.11.013. Epub 2018 Dec 20.

11.

Klf5 suppresses ERK signaling in mouse pluripotent stem cells.

Azami T, Matsumoto K, Jeon H, Waku T, Muratani M, Niwa H, Takahashi S, Ema M.

PLoS One. 2018 Nov 19;13(11):e0207321. doi: 10.1371/journal.pone.0207321. eCollection 2018.

12.

The dynamics of revascularization after white matter infarction monitored in Flt1-tdsRed and Flk1-GFP mice.

Shimauchi-Ohtaki H, Kurachi M, Naruse M, Shibasaki K, Sugio S, Matsumoto K, Ema M, Yoshimoto Y, Ishizaki Y.

Neurosci Lett. 2019 Jan 23;692:70-76. doi: 10.1016/j.neulet.2018.10.057. Epub 2018 Oct 31.

13.

Identification of non-substrate-like glycosyltransferase inhibitors from library screening: pitfalls & hits.

Ema M, Xu Y, Gehrke S, Wagner GK.

Medchemcomm. 2017 Nov 29;9(1):131-137. doi: 10.1039/c7md00550d. eCollection 2018 Jan 1.

14.

Historical control data on developmental toxicity studies in rats.

Kuwagata M, Sakai Y, Tanaka S, Takashima H, Katagiri R, Matsuoka T, Noritake K, Senuma M, Shimizu T, Hojo H, Ibi K, Kudo S, Oota T, Ube M, Miwa Y, Kajita S, Uesugi T, Yabe K, Tateishi T, Nakano N, Taniguchi T, Yamashita A, Hirano T, Kirihata Y, Sakai Y, Nishizawa S, Fujiwara M, Mineshima H, Horimoto M, Ema M.

Congenit Anom (Kyoto). 2019 Jul;59(4):125-131. doi: 10.1111/cga.12305. Epub 2018 Aug 29.

PMID:
30084506
15.

Fluorescent reporter transgenic mice for in vivo live imaging of angiogenesis and lymphangiogenesis.

Doh SJ, Yamakawa M, Santosa SM, Montana M, Guo K, Sauer JR, Curran N, Han KY, Yu C, Ema M, Rosenblatt MI, Chang JH, Azar DT.

Angiogenesis. 2018 Nov;21(4):677-698. doi: 10.1007/s10456-018-9629-2. Epub 2018 Jul 3. Review.

PMID:
29971641
16.

Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells.

Goto S, Onishi A, Misaki K, Yonemura S, Sugita S, Ito H, Ohigashi Y, Ema M, Sakaguchi H, Nishida K, Takahashi M.

Elife. 2018 Apr 3;7. pii: e32358. doi: 10.7554/eLife.32358.

17.

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.

Okada H, Yamada M, Kamimoto K, Kok CY, Kaneko K, Ema M, Miyajima A, Itoh T.

J Biol Chem. 2018 Apr 27;293(17):6214-6229. doi: 10.1074/jbc.RA118.002372. Epub 2018 Mar 9.

18.

Visualization of endothelial cell cycle dynamics in mouse using the Flt-1/eGFP-anillin system.

Herz K, Becker A, Shi C, Ema M, Takahashi S, Potente M, Hesse M, Fleischmann BK, Wenzel D.

Angiogenesis. 2018 May;21(2):349-361. doi: 10.1007/s10456-018-9601-1. Epub 2018 Feb 7.

PMID:
29417260
19.

Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction.

Kurotsu S, Osakabe R, Isomi M, Tamura F, Sadahiro T, Muraoka N, Kojima H, Haginiwa S, Tani H, Nara K, Kubota Y, Ema M, Fukuda K, Suzuki T, Ieda M.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):884-891. doi: 10.1016/j.bbrc.2017.11.094. Epub 2017 Nov 20.

PMID:
29158084
20.

Induction of oxidative stress by anticancer drugs in the presence and absence of cells.

Yokoyama C, Sueyoshi Y, Ema M, Mori Y, Takaishi K, Hisatomi H.

Oncol Lett. 2017 Nov;14(5):6066-6070. doi: 10.3892/ol.2017.6931. Epub 2017 Sep 14.

21.

A 104-week pulmonary toxicity assessment of long and short single-wall carbon nanotubes after a single intratracheal instillation in rats.

Honda K, Naya M, Takehara H, Kataura H, Fujita K, Ema M.

Inhal Toxicol. 2017 Sep;29(11):471-482. doi: 10.1080/08958378.2017.1394930. Epub 2017 Nov 7.

PMID:
29110549
22.

Klf5 maintains the balance of primitive endoderm versus epiblast specification during mouse embryonic development by suppression of Fgf4.

Azami T, Waku T, Matsumoto K, Jeon H, Muratani M, Kawashima A, Yanagisawa J, Manabe I, Nagai R, Kunath T, Nakamura T, Kurimoto K, Saitou M, Takahashi S, Ema M.

Development. 2017 Oct 15;144(20):3706-3718. doi: 10.1242/dev.150755. Epub 2017 Sep 4.

23.

Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis.

Zhong W, Gao X, Wang S, Han K, Ema M, Adams S, Adams RH, Rosenblatt MI, Chang JH, Azar DT.

Angiogenesis. 2017 Nov;20(4):581-598. doi: 10.1007/s10456-017-9572-7. Epub 2017 Aug 9.

24.

Length effects of single-walled carbon nanotubes on pulmonary toxicity after intratracheal instillation in rats.

Ema M, Takehara H, Naya M, Kataura H, Fujita K, Honda K.

J Toxicol Sci. 2017;42(3):367-378. doi: 10.2131/jts.42.367.

25.

Covalent inhibitors of LgtC: A blueprint for the discovery of non-substrate-like inhibitors for bacterial glycosyltransferases.

Xu Y, Smith R, Vivoli M, Ema M, Goos N, Gehrke S, Harmer NJ, Wagner GK.

Bioorg Med Chem. 2017 Jun 15;25(12):3182-3194. doi: 10.1016/j.bmc.2017.04.006. Epub 2017 Apr 11.

PMID:
28462843
26.

Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice.

Matsushita J, Inagaki S, Nishie T, Sakasai T, Tanaka J, Watanabe C, Mizutani KI, Miwa Y, Matsumoto K, Takara K, Naito H, Kidoya H, Takakura N, Nagai T, Takahashi S, Ema M.

Sci Rep. 2017 Apr 20;7:46597. doi: 10.1038/srep46597.

27.

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature.

Yamazaki T, Nalbandian A, Uchida Y, Li W, Arnold TD, Kubota Y, Yamamoto S, Ema M, Mukouyama YS.

Cell Rep. 2017 Mar 21;18(12):2991-3004. doi: 10.1016/j.celrep.2017.02.069.

28.

Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.

Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsushita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A.

JCI Insight. 2017 Feb 9;2(3):e90905. doi: 10.1172/jci.insight.90905.

29.

A review of toxicity studies on graphene-based nanomaterials in laboratory animals.

Ema M, Gamo M, Honda K.

Regul Toxicol Pharmacol. 2017 Apr;85:7-24. doi: 10.1016/j.yrtph.2017.01.011. Epub 2017 Feb 1. Review.

PMID:
28161457
30.

A review of reproductive and developmental toxicity of silver nanoparticles in laboratory animals.

Ema M, Okuda H, Gamo M, Honda K.

Reprod Toxicol. 2017 Jan;67:149-164. doi: 10.1016/j.reprotox.2017.01.005. Epub 2017 Jan 11. Review.

PMID:
28088501
31.
32.

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells.

Khoa le TP, Azami T, Tsukiyama T, Matsushita J, Tsukiyama-Fujii S, Takahashi S, Ema M.

PLoS One. 2016 Jul 13;11(7):e0159246. doi: 10.1371/journal.pone.0159246. eCollection 2016.

33.

Developmental regression of hyaloid vasculature is triggered by neurons.

Yoshikawa Y, Yamada T, Tai-Nagara I, Okabe K, Kitagawa Y, Ema M, Kubota Y.

J Exp Med. 2016 Jun 27;213(7):1175-83. doi: 10.1084/jem.20151966. Epub 2016 Jun 20.

34.

Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body.

Seita Y, Tsukiyama T, Iwatani C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Itoh Y, Imamura T, Nishimura M, Tooyama I, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M.

Sci Rep. 2016 Apr 25;6:24868. doi: 10.1038/srep24868.

35.

Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming.

Jeon H, Waku T, Azami T, Khoa le TP, Yanagisawa J, Takahashi S, Ema M.

PLoS One. 2016 Mar 4;11(3):e0150715. doi: 10.1371/journal.pone.0150715. eCollection 2016.

36.

Developmental toxicity of engineered nanomaterials in rodents.

Ema M, Gamo M, Honda K.

Toxicol Appl Pharmacol. 2016 May 15;299:47-52. doi: 10.1016/j.taap.2015.12.015. Epub 2015 Dec 22. Review.

PMID:
26721308
37.

Long-term retention of pristine multi-walled carbon nanotubes in rat lungs after intratracheal instillation.

Shinohara N, Nakazato T, Ohkawa K, Tamura M, Kobayashi N, Morimoto Y, Oyabu T, Myojo T, Shimada M, Yamamoto K, Tao H, Ema M, Naya M, Nakanishi J.

J Appl Toxicol. 2016 Apr;36(4):501-9. doi: 10.1002/jat.3271. Epub 2015 Dec 29.

38.

A review of toxicity studies of single-walled carbon nanotubes in laboratory animals.

Ema M, Gamo M, Honda K.

Regul Toxicol Pharmacol. 2016 Feb;74:42-63. doi: 10.1016/j.yrtph.2015.11.015. Epub 2015 Nov 24. Review.

PMID:
26619783
39.

Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus.

Matsuo K, Kuroda Y, Nango N, Shimoda K, Kubota Y, Ema M, Bakiri L, Wagner EF, Takeda Y, Yashiro W, Momose A.

Development. 2015 Nov 15;142(22):3912-20. doi: 10.1242/dev.123885. Epub 2015 Oct 1.

40.

Reproductive and developmental toxicity of carbon-based nanomaterials: A literature review.

Ema M, Hougaard KS, Kishimoto A, Honda K.

Nanotoxicology. 2016;10(4):391-412. doi: 10.3109/17435390.2015.1073811. Epub 2015 Sep 16. Review.

PMID:
26375634
41.

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling.

Hongu T, Funakoshi Y, Fukuhara S, Suzuki T, Sakimoto S, Takakura N, Ema M, Takahashi S, Itoh S, Kato M, Hasegawa H, Mochizuki N, Kanaho Y.

Nat Commun. 2015 Aug 4;6:7925. doi: 10.1038/ncomms8925.

PMID:
26239146
42.

Risk Assessment of the Carbon Nanotube Group.

Nakanishi J, Morimoto Y, Ogura I, Kobayashi N, Naya M, Ema M, Endoh S, Shimada M, Ogami A, Myojyo T, Oyabu T, Gamo M, Kishimoto A, Igarashi T, Hanai S.

Risk Anal. 2015 Oct;35(10):1940-56. doi: 10.1111/risa.12394. Epub 2015 May 5.

43.

Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression.

Katano M, Ema M, Nakachi Y, Mizuno Y, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Takahashi S, Okazaki Y, Okuda A.

Stem Cells. 2015 Apr;33(4):1089-101. doi: 10.1002/stem.1918.

44.

Neurons limit angiogenesis by titrating VEGF in retina.

Okabe K, Kobayashi S, Yamada T, Kurihara T, Tai-Nagara I, Miyamoto T, Mukouyama YS, Sato TN, Suda T, Ema M, Kubota Y.

Cell. 2014 Oct 23;159(3):584-96. doi: 10.1016/j.cell.2014.09.025.

45.

Functional compensation between Myc and PI3K signaling supports self-renewal of embryonic stem cells.

Hishida T, Nakachi Y, Mizuno Y, Katano M, Okazaki Y, Ema M, Takahashi S, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Hishida-Nozaki Y, Vazquez-Ferrer E, Sancho-Martinez I, Izpisua Belmonte JC, Okuda A.

Stem Cells. 2015 Mar;33(3):713-25. doi: 10.1002/stem.1893.

46.

Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow.

Kowata S, Isogai S, Murai K, Ito S, Tohyama K, Ema M, Hitomi J, Ishida Y.

Thromb Haemost. 2014 Oct;112(4):743-56. doi: 10.1160/TH14-02-0123. Epub 2014 Jun 26.

PMID:
24965909
47.

Roles of VEGF-A signalling in development, regeneration, and tumours.

Matsumoto K, Ema M.

J Biochem. 2014 Jul;156(1):1-10. doi: 10.1093/jb/mvu031. Epub 2014 May 16. Review.

PMID:
24839295
48.

Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.

Hasegawa Y, Daitoku Y, Mizuno S, Tanimoto Y, Mizuno-Iijima S, Matsuo M, Kajiwara N, Ema M, Oishi H, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K.

Exp Anim. 2014;63(2):183-91.

49.

Historical control data on developmental toxicity studies in rodents.

Ema M, Endoh K, Fukushima R, Fujii S, Hara H, Hirata-Koizumi M, Hirose A, Hojo H, Horimoto M, Hoshino N, Hosokawa Y, Imai Y, Inada H, Inawaka K, Itoh K, Katsumata Y, Izumi H, Kato H, Maeda M, Matsumoto K, Matsuo S, Matsuoka T, Matsuura I, Mineshima H, Miwa Y, Nakano N, Naya M, Noyori H, Ohta T, Oku H, Ono A, Shimizu T, Shimomura K, Takakura I, Tanaka R, Tateishi T, Tominaga Y, Uesugi T, Urakawa C, Yabe K, Yamashita A, Yamauchi T, Yokoi R.

Congenit Anom (Kyoto). 2014 Aug;54(3):150-61. doi: 10.1111/cga.12050.

PMID:
24666250
50.

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.

Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Mizuno-Iijima S, Mizuno S, Kajiwara N, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K.

Exp Anim. 2013;62(4):295-304.

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