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Items: 1 to 50 of 71

1.

Lineage marker expression on mouse hematopoietic stem cells.

Wang J, Liu Z, Zhang S, Wang X, Bai H, Xie M, Dong F, Ema H.

Exp Hematol. 2019 Aug;76:13-23.e2. doi: 10.1016/j.exphem.2019.07.001. Epub 2019 Jul 9.

PMID:
31299288
2.

[Emerging role of Mitochondria in Maintenance of Hematopoietic Stem Cells--Review].

Liu ZX, Dong F, Zhang S, Han MZ, Ema H.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Feb;27(1):277-282. doi: 10.7534/j.issn.1009-2137.2019.01.045. Review. Chinese.

PMID:
30738483
3.

Mouse acute leukemia develops independent of self-renewal and differentiation potentials in hematopoietic stem and progenitor cells.

Dong F, Bai H, Wang X, Zhang S, Wang Z, Xie M, Zhang S, Wang J, Hao S, Cheng T, Ema H.

Blood Adv. 2019 Feb 12;3(3):419-431. doi: 10.1182/bloodadvances.2018022400.

4.

TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells.

Wang X, Dong F, Zhang S, Yang W, Yu W, Wang Z, Zhang S, Wang J, Ma S, Wu P, Gao Y, Dong J, Tang F, Cheng T, Ema H.

Stem Cell Reports. 2018 Jul 10;11(1):274-287. doi: 10.1016/j.stemcr.2018.05.017. Epub 2018 Jun 21.

5.

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.

Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M, Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi H, Hirao A.

Cell Stem Cell. 2018 May 3;22(5):713-725.e8. doi: 10.1016/j.stem.2018.04.002. Epub 2018 Apr 26.

6.

PDK1 plays a vital role on hematopoietic stem cell function.

Hu T, Li C, Wang L, Zhang Y, Peng L, Cheng H, Chu Y, Wang W, Ema H, Gao Y, Ju Z, Yang Z, Wang X, Cheng T, Yuan W.

Sci Rep. 2017 Jul 10;7(1):4943. doi: 10.1038/s41598-017-05213-3.

7.

An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors.

Ieyasu A, Ishida R, Kimura T, Morita M, Wilkinson AC, Sudo K, Nishimura T, Ohehara J, Tajima Y, Lai CY, Otsu M, Nakamura Y, Ema H, Nakauchi H, Yamazaki S.

Stem Cell Reports. 2017 Mar 14;8(3):500-508. doi: 10.1016/j.stemcr.2017.01.015. Epub 2017 Feb 23.

8.

Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos.

Wang X, Gong Y, Ema H.

J Hematol Oncol. 2016 Jul 22;9(1):58. doi: 10.1186/s13045-016-0289-7. Review.

9.

A novel lymphoid progenitor cell population (LSK(low)) is restricted by p18(INK4c).

Dong F, Hao S, Ma S, Cheng H, Wang Y, Zhou W, Yuan W, Ema H, Cheng T.

Exp Hematol. 2016 Sep;44(9):874-885.e5. doi: 10.1016/j.exphem.2016.05.015. Epub 2016 Jun 8.

PMID:
27287689
10.

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

Furusawa J, Mizoguchi I, Chiba Y, Hisada M, Kobayashi F, Yoshida H, Nakae S, Tsuchida A, Matsumoto T, Ema H, Mizuguchi J, Yoshimoto T.

PLoS Pathog. 2016 Mar 18;12(3):e1005507. doi: 10.1371/journal.ppat.1005507. eCollection 2016 Mar.

11.

Guest editorial: Institute of Hematology and Blood Diseases Hospital in China.

Ema H.

Int J Hematol. 2016 May;103(5):486. doi: 10.1007/s12185-016-1967-5. Epub 2016 Mar 10. No abstract available.

PMID:
26964778
12.

Repopulation dynamics of single haematopoietic stem cells in mouse transplantation experiments: Importance of stem cell composition in competitor cells.

Ema H, Uchinomiya K, Morita Y, Suda T, Iwasa Y.

J Theor Biol. 2016 Apr 7;394:57-67. doi: 10.1016/j.jtbi.2016.01.010. Epub 2016 Jan 20.

PMID:
26802482
13.

Mechanisms of self-renewal in hematopoietic stem cells.

Wang Z, Ema H.

Int J Hematol. 2016 May;103(5):498-509. doi: 10.1007/s12185-015-1919-5. Epub 2015 Dec 12. Review.

PMID:
26662558
14.

Heterogeneity and hierarchy of hematopoietic stem cells.

Ema H, Morita Y, Suda T.

Exp Hematol. 2014 Feb;42(2):74-82.e2. doi: 10.1016/j.exphem.2013.11.004. Epub 2013 Nov 20. Review.

PMID:
24269919
15.

Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.

Yamamoto R, Morita Y, Ooehara J, Hamanaka S, Onodera M, Rudolph KL, Ema H, Nakauchi H.

Cell. 2013 Aug 29;154(5):1112-1126. doi: 10.1016/j.cell.2013.08.007.

16.

Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method.

Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, Otsu M, Yamaguchi T, Onodera M, Nakauchi H.

Biochem Biophys Res Commun. 2013 Jun 14;435(4):586-91. doi: 10.1016/j.bbrc.2013.05.017. Epub 2013 May 17.

PMID:
23685154
17.

Two anatomically distinct niches regulate stem cell activity.

Ema H, Suda T.

Blood. 2012 Sep 13;120(11):2174-81. doi: 10.1182/blood-2012-04-424507. Epub 2012 Jul 11. Review.

PMID:
22786878
18.

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche.

Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, Taketo MM, Karlsson S, Iwama A, Nakauchi H.

Cell. 2011 Nov 23;147(5):1146-58. doi: 10.1016/j.cell.2011.09.053.

19.

Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL.

Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S.

Exp Hematol. 2012 Feb;40(2):166-74.e3. doi: 10.1016/j.exphem.2011.11.003. Epub 2011 Nov 18.

PMID:
22101255
20.

Functional characterization of hematopoietic stem cells in the spleen.

Morita Y, Iseki A, Okamura S, Suzuki S, Nakauchi H, Ema H.

Exp Hematol. 2011 Mar;39(3):351-359.e3. doi: 10.1016/j.exphem.2010.12.008. Epub 2010 Dec 24.

PMID:
21185906
21.

Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.

Mashima R, Honda K, Yang Y, Morita Y, Inoue A, Arimura S, Nishina H, Ema H, Nakauchi H, Seed B, Oda H, Yamanashi Y.

Lab Invest. 2010 Sep;90(9):1357-64. doi: 10.1038/labinvest.2010.121. Epub 2010 Jun 14.

22.

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment.

Morita Y, Ema H, Nakauchi H.

J Exp Med. 2010 Jun 7;207(6):1173-82. doi: 10.1084/jem.20091318. Epub 2010 Apr 26.

23.

Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.

Okabe M, Otsu M, Ahn DH, Kobayashi T, Morita Y, Wakiyama Y, Onodera M, Eto K, Ema H, Nakauchi H.

Blood. 2009 Aug 27;114(9):1764-7. doi: 10.1182/blood-2009-02-203695. Epub 2009 Jun 29.

PMID:
19564635
24.

The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.

Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.

Stem Cells. 2009 May;27(5):1120-9. doi: 10.1002/stem.42.

25.

Stepwise development of hematopoietic stem cells from embryonic stem cells.

Matsumoto K, Isagawa T, Nishimura T, Ogaeri T, Eto K, Miyazaki S, Miyazaki J, Aburatani H, Nakauchi H, Ema H.

PLoS One. 2009;4(3):e4820. doi: 10.1371/journal.pone.0004820. Epub 2009 Mar 16.

26.

TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation.

Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H.

Blood. 2009 Feb 5;113(6):1250-6. doi: 10.1182/blood-2008-04-146480. Epub 2008 Oct 22.

PMID:
18945958
27.

Isolation of murine hematopoietic stem cells and progenitor cells.

Ema H, Morita Y, Nakauchi H, Matsuzaki Y.

Curr Protoc Immunol. 2005 Jul;Chapter 22:Unit 22B.1. doi: 10.1002/0471142735.im22b01s67.

PMID:
18432947
28.

Bloodlines of haematopoietic stem cell research in Japan.

Ema H, Nakauchi H.

Philos Trans R Soc Lond B Biol Sci. 2008 Jun 27;363(1500):2089-97. doi: 10.1098/rstb.2008.2263. Review.

29.

VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment.

Murakami M, Zheng Y, Hirashima M, Suda T, Morita Y, Ooehara J, Ema H, Fong GH, Shibuya M.

Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):658-64. doi: 10.1161/ATVBAHA.107.150433. Epub 2008 Jan 3.

PMID:
18174461
30.

Interleukin-27 directly induces differentiation in hematopoietic stem cells.

Seita J, Asakawa M, Ooehara J, Takayanagi S, Morita Y, Watanabe N, Fujita K, Kudo M, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto T.

Blood. 2008 Feb 15;111(4):1903-12. Epub 2007 Nov 27.

PMID:
18042804
31.

Cytokine signaling, lipid raft clustering, and HSC hibernation.

Yamazaki S, Iwama A, Morita Y, Eto K, Ema H, Nakauchi H.

Ann N Y Acad Sci. 2007 Jun;1106:54-63. Epub 2007 Apr 18. Review.

PMID:
17442772
32.

De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells.

Tadokoro Y, Ema H, Okano M, Li E, Nakauchi H.

J Exp Med. 2007 Apr 16;204(4):715-22. Epub 2007 Apr 9.

33.

Adult mouse hematopoietic stem cells: purification and single-cell assays.

Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H.

Nat Protoc. 2006;1(6):2979-87.

PMID:
17406558
34.

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction.

Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2349-54. Epub 2007 Feb 6.

35.

Effect of different dialyzer membranes on cutaneous microcirculation during hemodialysis.

Sato M, Morita H, Ema H, Yamaguchi S, Amano I.

Clin Nephrol. 2006 Dec;66(6):426-32.

PMID:
17176914
36.

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells.

Yamazaki S, Iwama A, Takayanagi S, Morita Y, Eto K, Ema H, Nakauchi H.

EMBO J. 2006 Aug 9;25(15):3515-23. Epub 2006 Jul 20.

37.

Non-side-population hematopoietic stem cells in mouse bone marrow.

Morita Y, Ema H, Yamazaki S, Nakauchi H.

Blood. 2006 Oct 15;108(8):2850-6. Epub 2006 Jun 27.

PMID:
16804114
38.

Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo.

Furuta C, Ema H, Takayanagi S, Ogaeri T, Okamura D, Matsui Y, Nakauchi H.

Development. 2006 Jul;133(14):2771-9.

39.

[Diversity of hematopoietic stem cells].

Ema H, Kinda M, Takano Y, Oehara A, Maeda A, Nakauchi H.

Rinsho Ketsueki. 2005 Mar;46(3):170-8. Review. Japanese. No abstract available.

PMID:
16447711
40.

Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development.

Matsubara A, Iwama A, Yamazaki S, Furuta C, Hirasawa R, Morita Y, Osawa M, Motohashi T, Eto K, Ema H, Kitamura T, Vestweber D, Nakauchi H.

J Exp Med. 2005 Dec 5;202(11):1483-92. Epub 2005 Nov 28.

41.

Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice.

Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H.

Dev Cell. 2005 Jun;8(6):907-14.

42.

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.

Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, Tsukui H, Ema H, Kamijo T, Katoh-Fukui Y, Koseki H, van Lohuizen M, Nakauchi H.

Immunity. 2004 Dec;21(6):843-51.

43.

[Mechanisms controlling the fate of hematopoietic stem cells].

Ema H.

Tanpakushitsu Kakusan Koso. 2004 May;49(6):734-40. Review. Japanese. No abstract available.

PMID:
15160882
44.
45.

"Homing to Niche," a new criterion for hematopoietic stem cells?

Ema H, Nakauchi H.

Immunity. 2004 Jan;20(1):1-2.

46.

Self-renewal and lineage restriction of hematopoietic stem cells.

Ema H, Nakauchi H.

Curr Opin Genet Dev. 2003 Oct;13(5):508-12. Review.

PMID:
14550417
47.

Full reconstitution of hematopoietic system by murine umbilical cord blood.

Migishima F, Oikawa A, Kondo S, Ema H, Morita Y, Nakauchi H, Yokoyama M, Song SY, Nishijima M, Okabe M, Shinohara N.

Transplantation. 2003 Jun 15;75(11):1820-6.

PMID:
12811240
48.

Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells.

Tahara-Hanaoka S, Sudo K, Ema H, Miyoshi H, Nakauchi H.

Exp Hematol. 2002 Jan;30(1):11-7.

PMID:
11823032
49.

Quantitative assessment of the stem cell self-renewal capacity.

Nakauchi H, Sudo K, Ema H.

Ann N Y Acad Sci. 2001 Jun;938:18-24; discussion 24-5. Review.

PMID:
11458506
50.

Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver.

Hsu HC, Ema H, Osawa M, Nakamura Y, Suda T, Nakauchi H.

Blood. 2000 Dec 1;96(12):3757-62.

PMID:
11090057

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