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Items: 1 to 50 of 84

1.

The Novel C-terminal Truncated 90-kDa Isoform of Topoisomerase IIα (TOP2α/90) Is a Determinant of Etoposide Resistance in K562 Leukemia Cells via Heterodimerization with the TOP2α/170 Isoform.

Kanagasabai R, Karmahapatra S, Kientz CA, Yu Y, Hernandez VA, Kania EE, Yalowich JC, Elton TS.

Mol Pharmacol. 2018 May;93(5):515-525. doi: 10.1124/mol.117.111567. Epub 2018 Mar 7.

PMID:
29514855
2.

Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform.

Kanagasabai R, Serdar L, Karmahapatra S, Kientz CA, Ellis J, Ritke MK, Elton TS, Yalowich JC.

J Pharmacol Exp Ther. 2017 Jan;360(1):152-163. Epub 2016 Nov 10.

3.

Retraction notice to "TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2".

Martin MM, Buckenberger JA, Knoell DL, Strauch AR, Elton TS.

Mol Cell Endocrinol. 2016 Oct 15;434:288. doi: 10.1016/j.mce.2016.08.003. No abstract available.

PMID:
27519873
4.

Experimental procedures to identify and validate specific mRNA targets of miRNAs.

Elton TS, Yalowich JC.

EXCLI J. 2015 Jul 2;14:758-90. doi: 10.17179/excli2015-319. eCollection 2015. Review.

5.

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer.

Wu Y, Crawford M, Mao Y, Lee RJ, Davis IC, Elton TS, Lee LJ, Nana-Sinkam SP.

Mol Ther Nucleic Acids. 2013 Apr 16;2:e84. doi: 10.1038/mtna.2013.14.

6.

Circulating miRNAs: novel biomarkers of acute coronary syndrome?

Pleister A, Selemon H, Elton SM, Elton TS.

Biomark Med. 2013 Apr;7(2):287-305. doi: 10.2217/bmm.13.8. Review.

PMID:
23547823
7.

Regulation of the MIR155 host gene in physiological and pathological processes.

Elton TS, Selemon H, Elton SM, Parinandi NL.

Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Review.

PMID:
23246696
8.

Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N,N'-bis-2-mercaptoethyl isophthalamide.

Patel RB, Kotha SR, Sauers LA, Malireddy S, Gurney TO, Gupta NN, Elton TS, Magalang UJ, Marsh CB, Haley BE, Parinandi NL.

Toxicol Mech Methods. 2012 Jun;22(5):383-96. doi: 10.3109/15376516.2012.673089.

9.

MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex.

Belevych AE, Sansom SE, Terentyeva R, Ho HT, Nishijima Y, Martin MM, Jindal HK, Rochira JA, Kunitomo Y, Abdellatif M, Carnes CA, Elton TS, Györke S, Terentyev D.

PLoS One. 2011;6(12):e28324. doi: 10.1371/journal.pone.0028324. Epub 2011 Dec 6.

10.

MicroRNAs in cardiovascular disease.

Elton TS, Khan M, Terentyev D.

F1000 Med Rep. 2011;3:10. doi: 10.3410/M3-10. Epub 2011 May 3.

11.

Intronic microRNA suppresses endothelial nitric oxide synthase expression and endothelial cell proliferation via inhibition of STAT3 signaling.

Yan L, Hao H, Elton TS, Liu Z, Ou H.

Mol Cell Biochem. 2011 Nov;357(1-2):9-19. doi: 10.1007/s11010-011-0870-x. Epub 2011 May 25.

PMID:
21611796
12.

Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology.

Nishijima Y, Sridhar A, Bonilla I, Velayutham M, Khan M, Terentyeva R, Li C, Kuppusamy P, Elton TS, Terentyev D, Györke S, Zweier JL, Cardounel AJ, Carnes CA.

Cardiovasc Res. 2011 Jul 1;91(1):71-9. doi: 10.1093/cvr/cvr087. Epub 2011 Apr 1.

13.

miRNAs got rhythm.

Elton TS, Martin MM, Sansom SE, Belevych AE, Györke S, Terentyev D.

Life Sci. 2011 Feb 28;88(9-10):373-83. doi: 10.1016/j.lfs.2010.11.022. Epub 2010 Dec 3. Review.

PMID:
21130781
14.

Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins.

Elton TS, Sansom SE, Martin MM.

RNA Biol. 2010 Sep-Oct;7(5):540-7. Epub 2010 Sep 1.

15.

Cardiovascular Disease, Single Nucleotide Polymorphisms; and the Renin Angiotensin System: Is There a MicroRNA Connection?

Elton TS, Sansom SE, Martin MM.

Int J Hypertens. 2010 Aug 4;2010. pii: 281692. doi: 10.4061/2010/281692.

16.

miR-802 regulates human angiotensin II type 1 receptor expression in intestinal epithelial C2BBe1 cells.

Sansom SE, Nuovo GJ, Martin MM, Kotha SR, Parinandi NL, Elton TS.

Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G632-42. doi: 10.1152/ajpgi.00120.2010. Epub 2010 Jun 17.

17.

Heart rate control with adrenergic blockade: clinical outcomes in cardiovascular medicine.

Feldman D, Elton TS, Menachemi DM, Wexler RK.

Vasc Health Risk Manag. 2010 Jun 1;6:387-97. Review.

18.

MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response.

Cremer TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB, Elton TS, Gunn JS, Amer A, Kanneganti TD, Schlesinger LS, Butchar JP, Tridandapani S.

PLoS One. 2009 Dec 30;4(12):e8508. doi: 10.1371/journal.pone.0008508.

19.

Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains.

Kuhn DE, Nuovo GJ, Terry AV Jr, Martin MM, Malana GE, Sansom SE, Pleister AP, Beck WD, Head E, Feldman DS, Elton TS.

J Biol Chem. 2010 Jan 8;285(2):1529-43. doi: 10.1074/jbc.M109.033407. Epub 2009 Nov 6. Retraction in: J Biol Chem. 2013 Feb 8;288(6):4228.

20.

A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets.

Nuovo GJ, Elton TS, Nana-Sinkam P, Volinia S, Croce CM, Schmittgen TD.

Nat Protoc. 2009;4(1):107-15. doi: 10.1038/nprot.2008.215. Epub 2009 Jan 8.

21.

miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2.

Terentyev D, Belevych AE, Terentyeva R, Martin MM, Malana GE, Kuhn DE, Abdellatif M, Feldman DS, Elton TS, Györke S.

Circ Res. 2009 Feb 27;104(4):514-21. doi: 10.1161/CIRCRESAHA.108.181651. Epub 2009 Jan 8.

22.

Mapping of DDR1 distribution and oligomerization on the cell surface by FRET microscopy.

Mihai C, Chotani M, Elton TS, Agarwal G.

J Mol Biol. 2009 Jan 16;385(2):432-45. doi: 10.1016/j.jmb.2008.10.067. Epub 2008 Nov 5. Erratum in: J Mol Biol. 2013 May 27;425(10):1846.

23.

Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2.

Blissett AR, Garbellini D, Calomeni EP, Mihai C, Elton TS, Agarwal G.

J Mol Biol. 2009 Jan 23;385(3):902-11. doi: 10.1016/j.jmb.2008.10.060. Epub 2008 Oct 30.

24.

Purine metabolism in heart failure: oxidant biology and therapeutic indications.

Bauer JA, Moffatt-Bruce SD, Elton TS, Feldman D.

Congest Heart Fail. 2008 Sep-Oct;14(5):283-4. doi: 10.1111/j.1751-7133.2008.00011.x. No abstract available.

25.

Follicular dendritic cells and human immunodeficiency virus type 1 transcription in CD4+ T cells.

Thacker TC, Zhou X, Estes JD, Jiang Y, Keele BF, Elton TS, Burton GF.

J Virol. 2009 Jan;83(1):150-8. doi: 10.1128/JVI.01652-08. Epub 2008 Oct 29.

26.

Protein kinase C-epsilon induces caveolin-dependent internalization of vascular adenosine 5'-triphosphate-sensitive K+ channels.

Jiao J, Garg V, Yang B, Elton TS, Hu K.

Hypertension. 2008 Sep;52(3):499-506. doi: 10.1161/HYPERTENSIONAHA.108.110817. Epub 2008 Jul 28. Erratum in: Hypertension. 2011 Oct;58(4):e29.

PMID:
18663158
27.

Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts.

Kuhn DE, Nuovo GJ, Martin MM, Malana GE, Pleister AP, Jiang J, Schmittgen TD, Terry AV Jr, Gardiner K, Head E, Feldman DS, Elton TS.

Biochem Biophys Res Commun. 2008 Jun 6;370(3):473-7. doi: 10.1016/j.bbrc.2008.03.120. Epub 2008 Apr 1. Retraction in: Biochem Biophys Res Commun. 2013 Jul 5;436(3):564.

28.

Mechanisms of disease: detrimental adrenergic signaling in acute decompensated heart failure.

Feldman DS, Elton TS, Sun B, Martin MM, Ziolo MT.

Nat Clin Pract Cardiovasc Med. 2008 Apr;5(4):208-18. doi: 10.1038/ncpcardio1127. Epub 2008 Feb 19. Review.

29.

Experimental validation of miRNA targets.

Kuhn DE, Martin MM, Feldman DS, Terry AV Jr, Nuovo GJ, Elton TS.

Methods. 2008 Jan;44(1):47-54. Review.

30.

Real-time PCR quantification of precursor and mature microRNA.

Schmittgen TD, Lee EJ, Jiang J, Sarkar A, Yang L, Elton TS, Chen C.

Methods. 2008 Jan;44(1):31-8. Review.

31.

Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes.

Sethupathy P, Borel C, Gagnebin M, Grant GR, Deutsch S, Elton TS, Hatzigeorgiou AG, Antonarakis SE.

Am J Hum Genet. 2007 Aug;81(2):405-13. Epub 2007 Jul 12.

32.

TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways.

Martin MM, Buckenberger JA, Jiang J, Malana GE, Knoell DL, Feldman DS, Elton TS.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L790-9. Epub 2007 Jun 29. Retraction in: Am J Physiol Lung Cell Mol Physiol. 2012 Apr 1;302(7):L719.

33.

The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microRNA-155 binding.

Martin MM, Buckenberger JA, Jiang J, Malana GE, Nuovo GJ, Chotani M, Feldman DS, Schmittgen TD, Elton TS.

J Biol Chem. 2007 Aug 17;282(33):24262-9. Epub 2007 Jun 22. Retraction in: J Biol Chem. 2013 Feb 8;288(6):4227.

34.

Angiotensin II type 1 receptor gene regulation: transcriptional and posttranscriptional mechanisms.

Elton TS, Martin MM.

Hypertension. 2007 May;49(5):953-61. Epub 2007 Feb 26. Review. No abstract available.

PMID:
17325239
35.

Discoidin domain receptor 2 inhibits fibrillogenesis of collagen type 1.

Mihai C, Iscru DF, Druhan LJ, Elton TS, Agarwal G.

J Mol Biol. 2006 Sep 1;361(5):864-76. Epub 2006 Aug 1.

PMID:
16884738
36.

Abnormal diastolic currents in ventricular myocytes from spontaneous hypertensive heart failure rats.

Sridhar A, Dech SJ, Lacombe VA, Elton TS, McCune SA, Altschuld RA, Carnes CA.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2192-8. Epub 2006 Jun 9.

37.

MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts.

Martin MM, Lee EJ, Buckenberger JA, Schmittgen TD, Elton TS.

J Biol Chem. 2006 Jul 7;281(27):18277-84. Epub 2006 May 4. Retraction in: J Biol Chem. 2013 Feb 8;288(6):4226.

38.

TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2.

Martin MM, Buckenberger JA, Knoell DL, Strauch AR, Elton TS.

Mol Cell Endocrinol. 2006 Apr 25;249(1-2):21-31. Epub 2006 Feb 28. Retraction in: Mol Cell Endocrinol. 2016 Oct 15;434:288.

PMID:
16504375
39.

Sarcosine1, glycine8 angiotensin II is a functional AT1 angiotensin receptor antagonist.

Speth RC, Kim KH, Elton TS, Simasko S.

Endocrine. 2005 Mar;26(2):83-7.

PMID:
15888919
40.

Transcriptional regulation of the AT1 receptor gene in immortalized human trophoblast cells.

Duffy AA, Martin MM, Elton TS.

Biochim Biophys Acta. 2004 Nov 5;1680(3):158-70. Retraction in: Biochim Biophys Acta. 2013 Sep;1829(9):980.

PMID:
15507319
41.

Translation of the human angiotensin II type 1 receptor mRNA is mediated by a highly efficient internal ribosome entry site.

Martin MM, Garcia JA, McFarland JD, Duffy AA, Gregson JP, Elton TS.

Mol Cell Endocrinol. 2003 Dec 30;212(1-2):51-61.

PMID:
14654250
42.

Alternative splicing: a novel mechanism to fine-tune the expression and function of the human AT1 receptor.

Elton TS, Martin MM.

Trends Endocrinol Metab. 2003 Mar;14(2):66-71. Review.

PMID:
12591176
43.

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression.

Chandrasekharan NV, Dai H, Roos KL, Evanson NK, Tomsik J, Elton TS, Simmons DL.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. Epub 2002 Sep 19.

44.

Regulation of angiotensin II-induced G protein signaling by phosducin-like protein.

McLaughlin JN, Thulin CD, Bray SM, Martin MM, Elton TS, Willardson BM.

J Biol Chem. 2002 Sep 20;277(38):34885-95. Epub 2002 Jul 9.

45.

The transcription factors Sp1 and Sp3 are required for human angiotensin II type 1 receptor gene expression in H295-R cells.

Zhao X, Martin MM, Elton TS.

Biochim Biophys Acta. 2001 Dec 30;1522(3):195-206.

PMID:
11779634
46.

Identification and characterization of functional angiotensin II type 1 receptors on immortalized human fetal aortic vascular smooth muscle cells.

Martin MM, Victor X, Zhao X, McDougall JK, Elton TS.

Mol Cell Endocrinol. 2001 Oct 25;183(1-2):81-91.

PMID:
11604228
47.

Human angiotensin II type 1 receptor isoforms encoded by messenger RNA splice variants are functionally distinct.

Martin MM, Willardson BM, Burton GF, White CR, McLaughlin JN, Bray SM, Ogilvie JW Jr, Elton TS.

Mol Endocrinol. 2001 Feb;15(2):281-93.

PMID:
11158334
48.

Basal level transcriptional regulation of the human angiotensin II type 1 receptor gene.

Zhao X, Martin MM, Elton TS.

Biochim Biophys Acta. 2000 Nov 15;1494(1-2):181-4.

PMID:
11072083
49.

Molecular cloning and characterization of the human phosducin-like protein (hPhLP) promoter.

Lazarov ME, Martin MM, Willardson BM, Elton TS.

Biochim Biophys Acta. 2000 Jul 24;1492(2-3):460-4.

PMID:
10899582
50.

Characterization of the promoter-directing expression of growth hormone in a monocyte cell line.

Weigent DA, Vines CR, Long JC, Blalock JE, Elton TS.

Neuroimmunomodulation. 2000;7(3):126-34.

PMID:
10754400

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