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Items: 1 to 50 of 657

1.

A Randomized, Double-Blind, Placebo-Controlled, First-Time-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects.

Han K, Cremer J, Elston R, Oliver S, Baptiste-Brown S, Chen S, Gardiner D, Davies M, Saunders J, Hamatake R, Losos J, Leivers M, Hood S, van der Berg F, Paff M, Ritter JM, Theodore D.

Clin Pharmacol Drug Dev. 2019 Aug;8(6):790-801. doi: 10.1002/cpdd.670. Epub 2019 Mar 12.

2.

Fisher's influence on me.

Elston RC.

Genet Epidemiol. 2018 Dec;42(8):849-853. doi: 10.1002/gepi.22165. Epub 2018 Oct 8.

PMID:
30298598
3.

Adjustment for covariates using summary statistics of genome-wide association studies.

Wang T, Xue X, Xie X, Ye K, Zhu X, Elston RC.

Genet Epidemiol. 2018 Dec;42(8):812-825. doi: 10.1002/gepi.22148. Epub 2018 Sep 20.

PMID:
30238496
4.

How Consistent are Genetic Factors in Explaining Leisure-Time Physical Activity and Sport Participation? The Portuguese Healthy Families Study.

Pereira S, Katzmarzyk PT, Gomes TN, Elston R, Maia J.

Twin Res Hum Genet. 2018 Oct;21(5):369-377. doi: 10.1017/thg.2018.47. Epub 2018 Jul 6.

PMID:
29976260
5.

ONETOOL for the analysis of family-based big data.

Song YE, Lee S, Park K, Elston RC, Yang HJ, Won S.

Bioinformatics. 2018 Aug 15;34(16):2851-2853. doi: 10.1093/bioinformatics/bty180.

6.

Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.

Sun X, Chandar AK, Canto MI, Thota PN, Brock M, Shaheen NJ, Beer DG, Wang JS, Falk GW, Iyer PG, Abrams JA, Venkat-Ramani M, Veigl M, Miron A, Willis J, Patil DT, Nalbantoglu I, Guda K, Markowitz SD, Zhu X, Elston R, Chak A.

PLoS One. 2017 Oct 26;12(10):e0184962. doi: 10.1371/journal.pone.0184962. eCollection 2017.

7.

Correcting for Ascertainment.

Ewens W, Elston RC.

Methods Mol Biol. 2017;1666:211-232. doi: 10.1007/978-1-4939-7274-6_11.

PMID:
28980248
8.

Statistical Genetic Terminology.

Elston RC, Satagopan J, Sun S.

Methods Mol Biol. 2017;1666:1-9. doi: 10.1007/978-1-4939-7274-6_1.

PMID:
28980238
9.

Applying family analyses to electronic health records to facilitate genetic research.

Huang X, Elston RC, Rosa GJ, Mayer J, Ye Z, Kitchner T, Brilliant MH, Page D, Hebbring SJ, Stegle O.

Bioinformatics. 2018 Feb 15;34(4):635-642. doi: 10.1093/bioinformatics/btx569.

10.

On the association analysis of CNV data: a fast and robust family-based association method.

Liu M, Moon S, Wang L, Kim S, Kim YJ, Hwang MY, Kim YJ, Elston RC, Kim BJ, Won S.

BMC Bioinformatics. 2017 Apr 18;18(1):217. doi: 10.1186/s12859-017-1622-z.

11.

Linkage and related analyses of Barrett's esophagus and its associated adenocarcinomas.

Sun X, Elston R, Falk GW, Grady WM, Faulx A, Mittal SK, Canto MI, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Willis JE, Guda K, Markowitz S, Barnholtz-Sloan JS, Chandar A, Brock W, Chak A.

Mol Genet Genomic Med. 2016 Mar 14;4(4):407-19. doi: 10.1002/mgg3.211. eCollection 2016 Jul.

12.

Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia.

Fecteau RE, Kong J, Kresak A, Brock W, Song Y, Fujioka H, Elston R, Willis JE, Lynch JP, Markowitz SD, Guda K, Chak A.

JAMA Oncol. 2016 Oct 1;2(10):1333-1339. doi: 10.1001/jamaoncol.2016.2054.

13.

Immunoglobulin G genotypes and the risk of schizophrenia.

Pandey JP, Namboodiri AM, Elston RC.

Hum Genet. 2016 Oct;135(10):1175-9. doi: 10.1007/s00439-016-1706-2. Epub 2016 Jul 8.

14.

Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis.

Wang L, Lee S, Gim J, Qiao D, Cho M, Elston RC, Silverman EK, Won S.

Genet Epidemiol. 2016 Sep;40(6):502-11. doi: 10.1002/gepi.21985. Epub 2016 Jun 17.

15.

Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).

Williams RC, Elston RC, Kumar P, Knowler WC, Abboud HE, Adler S, Bowden DW, Divers J, Freedman BI, Igo RP Jr, Ipp E, Iyengar SK, Kimmel PL, Klag MJ, Kohn O, Langefeld CD, Leehey DJ, Nelson RG, Nicholas SB, Pahl MV, Parekh RS, Rotter JI, Schelling JR, Sedor JR, Shah VO, Smith MW, Taylor KD, Thameem F, Thornley-Brown D, Winkler CA, Guo X, Zager P, Hanson RL; FIND Research Group.

BMC Genomics. 2016 May 4;17:325. doi: 10.1186/s12864-016-2654-x.

16.

Predicting Barrett's Esophagus in Families: An Esophagus Translational Research Network (BETRNet) Model Fitting Clinical Data to a Familial Paradigm.

Sun X, Elston RC, Barnholtz-Sloan JS, Falk GW, Grady WM, Faulx A, Mittal SK, Canto M, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Tian YD, Willis JE, Guda K, Markowitz SD, Chandar A, Warfe JM, Brock W, Chak A.

Cancer Epidemiol Biomarkers Prev. 2016 May;25(5):727-35. doi: 10.1158/1055-9965.EPI-15-0832. Epub 2016 Feb 29.

17.

A weighted U statistic for association analyses considering genetic heterogeneity.

Wei C, Elston RC, Lu Q.

Stat Med. 2016 Jul 20;35(16):2802-14. doi: 10.1002/sim.6877. Epub 2016 Feb 1.

18.

A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis.

Markowitz SD, Nock NL, Schmit SL, Stadler ZK, Joseph V, Zhang L, Willis JE, Scacheri P, Veigl M, Adams MD, Raskin L, Sullivan JF, Stratton K, Shia J, Ellis N, Rennert HS, Manschreck C, Li L, Offit K, Elston RC, Rennert G, Gruber SB.

PLoS One. 2016 Jan 11;11(1):e0146435. doi: 10.1371/journal.pone.0146435. eCollection 2016.

19.

Interferon-free regimens containing setrobuvir for patients with genotype 1 chronic hepatitis C: a randomized, multicenter study.

Jensen DM, Brunda M, Elston R, Gane EJ, George J, Glavini K, Hammond JM, Le Pogam S, Nájera I, Passe S, Piekarska A, Rodriguez I, Zeuzem S, Chu T; ANNAPURNA study investigators.

Liver Int. 2016 Apr;36(4):505-14. doi: 10.1111/liv.12997. Epub 2015 Dec 12.

PMID:
26519669
20.

2nd International Conference on Progressive Multifocal Leukoencephalopathy (PML) 2015: JCV virology, progressive multifocal leukoencephalopathy pathogenesis, diagnosis and risk stratification, and new approaches to prevention and treatment.

Patera AC, Butler SL, Cinque P, Clifford DB, Elston R, Garcea RL, Major EO, Pavlovic D, Peterson IS, Ryan AM, Tyler KL, Weber T; PML Consortium.

J Neurovirol. 2015 Dec;21(6):702-5. doi: 10.1007/s13365-015-0392-5. No abstract available.

PMID:
26501778
21.

The Pelvis and Beyond: Musculoskeletal Tender Points in Women With Chronic Pelvic Pain.

Sanses TV, Chelimsky G, McCabe NP, Zolnoun D, Janata J, Elston R, Buffington CA, Simpson P, Zhang L, Chelimsky T.

Clin J Pain. 2016 Aug;32(8):659-65. doi: 10.1097/AJP.0000000000000307.

22.

On the Estimation of Heritability with Family-Based and Population-Based Samples.

Kim Y, Lee Y, Lee S, Kim NH, Lim J, Kim YJ, Oh JH, Min H, Lee M, Seo HJ, Lee SH, Sung J, Cho NH, Kim BJ, Han BG, Elston RC, Won S, Lee J.

Biomed Res Int. 2015;2015:671349. doi: 10.1155/2015/671349. Epub 2015 Aug 3.

23.

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).

Iyengar SK, Sedor JR, Freedman BI, Kao WH, Kretzler M, Keller BJ, Abboud HE, Adler SG, Best LG, Bowden DW, Burlock A, Chen YD, Cole SA, Comeau ME, Curtis JM, Divers J, Drechsler C, Duggirala R, Elston RC, Guo X, Huang H, Hoffmann MM, Howard BV, Ipp E, Kimmel PL, Klag MJ, Knowler WC, Kohn OF, Leak TS, Leehey DJ, Li M, Malhotra A, März W, Nair V, Nelson RG, Nicholas SB, O'Brien SJ, Pahl MV, Parekh RS, Pezzolesi MG, Rasooly RS, Rotimi CN, Rotter JI, Schelling JR, Seldin MF, Shah VO, Smiles AM, Smith MW, Taylor KD, Thameem F, Thornley-Brown DP, Truitt BJ, Wanner C, Weil EJ, Winkler CA, Zager PG, Igo RP Jr, Hanson RL, Langefeld CD; Family Investigation of Nephropathy and Diabetes (FIND).

PLoS Genet. 2015 Aug 25;11(8):e1005352. doi: 10.1371/journal.pgen.1005352. eCollection 2015 Aug.

24.

Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation.

Huang Y, Wang C, Yao Y, Zuo X, Chen S, Xu C, Zhang H, Lu Q, Chang L, Wang F, Wang P, Zhang R, Hu Z, Song Q, Yang X, Li C, Li S, Zhao Y, Yang Q, Yin D, Wang X, Si W, Li X, Xiong X, Wang D, Huang Y, Luo C, Li J, Wang J, Chen J, Wang L, Wang L, Han M, Ye J, Chen F, Liu J, Liu Y, Wu G, Yang B, Cheng X, Liao Y, Wu Y, Ke T, Chen Q, Tu X, Elston R, Rao S, Yang Y, Xia Y, Wang QK.

PLoS Genet. 2015 Aug 12;11(8):e1005393. doi: 10.1371/journal.pgen.1005393. eCollection 2015 Aug.

25.

Defining "mutation" and "polymorphism" in the era of personal genomics.

Karki R, Pandya D, Elston RC, Ferlini C.

BMC Med Genomics. 2015 Jul 15;8:37. doi: 10.1186/s12920-015-0115-z.

26.

Denman Island disease in Washington State, USA: distribution and prevalence in Pacific and Olympia oysters.

Elston R, Friedman C, Gustafson L, Meyer G, Rogers R.

Dis Aquat Organ. 2015 May 21;114(2):147-54. doi: 10.3354/dao02862.

PMID:
25993889
27.

Reply to Ashktorab et al.: Mutational landscape of colon cancers in African Americans.

Guda K, Veigl ML, Varadan V, Nosrati A, Ravi L, Lutterbaugh J, Beard L, Willson JK, Sedwick WD, Wang ZJ, Molyneaux N, Miron A, Adams MD, Elston RC, Markowitz SD, Willis JE.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2853. doi: 10.1073/pnas.1505059112. Epub 2015 May 4. No abstract available.

28.

Novel approaches to the analysis of family data in genetic epidemiology.

Morris N, Elston RC, Barnholtz-Sloan JS, Sun X.

Front Genet. 2015 Feb 6;6:27. doi: 10.3389/fgene.2015.00027. eCollection 2015. No abstract available.

29.

Statistical interactions and Bayes estimation of log odds in case-control studies.

Satagopan JM, Olson SH, Elston RC.

Stat Methods Med Res. 2017 Apr;26(2):1021-1038. doi: 10.1177/0962280214567140. Epub 2015 Jan 12.

30.

Novel recurrently mutated genes in African American colon cancers.

Guda K, Veigl ML, Varadan V, Nosrati A, Ravi L, Lutterbaugh J, Beard L, Willson JK, Sedwick WD, Wang ZJ, Molyneaux N, Miron A, Adams MD, Elston RC, Markowitz SD, Willis JE.

Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1149-54. doi: 10.1073/pnas.1417064112. Epub 2015 Jan 12.

31.

Putative linkage signals identified for breast cancer in African American families.

Ochs-Balcom HM, Sun X, Chen Y, Barnholtz-Sloan J, Erwin DO, Jandorf L, Sucheston-Campbell L, Elston RC.

Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):442-7. doi: 10.1158/1055-9965.EPI-14-1131. Epub 2014 Dec 4.

32.

On the analysis of a repeated measure design in genome-wide association analysis.

Lee Y, Park S, Moon S, Lee J, Elston RC, Lee W, Won S.

Int J Environ Res Public Health. 2014 Nov 28;11(12):12283-303. doi: 10.3390/ijerph111212283.

33.

Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder.

Ginns EI, Galdzicka M, Elston RC, Song YE, Paul SM, Egeland JA.

Mol Psychiatry. 2015 Oct;20(10):1212-8. doi: 10.1038/mp.2014.118. Epub 2014 Oct 14.

PMID:
25311364
34.

The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.

Wang YJ, Tayo BO, Bandyopadhyay A, Wang H, Feng T, Franceschini N, Tang H, Gao J, Sung YJ; COGENT BP consortium, Elston RC, Williams SM, Cooper RS, Mu TW, Zhu X.

PLoS Genet. 2014 Sep 18;10(9):e1004641. doi: 10.1371/journal.pgen.1004641. eCollection 2014 Sep.

35.

Commingling analysis of age-of-onset in bipolar I disorder and the morbid risk for major psychoses in first degree relatives of bipolar I probands.

Grigoroiu-Serbanescu M, Rietschel M, Hauser J, Czerski PM, Herms S, Sun X, Wickramaratne P, Elston RC.

J Affect Disord. 2014 Oct;168:197-204. doi: 10.1016/j.jad.2014.06.054. Epub 2014 Jul 9.

PMID:
25063958
36.

Genetic-based prediction of disease traits: prediction is very difficult, especially about the future.

Schrodi SJ, Mukherjee S, Shan Y, Tromp G, Sninsky JJ, Callear AP, Carter TC, Ye Z, Haines JL, Brilliant MH, Crane PK, Smelser DT, Elston RC, Weeks DE.

Front Genet. 2014 Jun 2;5:162. doi: 10.3389/fgene.2014.00162. eCollection 2014. Review.

37.

Interstitial Cystitis - Elucidation of Psychophysiologic and Autonomic Characteristics (the ICEPAC Study): design and methods.

Chelimsky T, Chelimsky G, McCabe NP, Louttit M, Hijaz A, Mahajan S, Sanses T, Buffington CT, Fenton B, Janicki T, Ialacci S, Veizi E, Zhang D, Daneshgari F, Elston R, Janata J.

J Pain Res. 2014 May 8;7:243-53. doi: 10.2147/JPR.S58853. eCollection 2014.

38.

Analysis pipeline for the epistasis search - statistical versus biological filtering.

Sun X, Lu Q, Mukherjee S, Crane PK, Elston R, Ritchie MD.

Front Genet. 2014 Apr 30;5:106. doi: 10.3389/fgene.2014.00106. eCollection 2014. Review. Erratum in: Front Genet. 2014;5:350. Mukheerjee, Shubhabrata [corrected to Mukherjee, Shubhabrata].

39.

Autonomic testing of women with interstitial cystitis/bladder pain syndrome.

Chelimsky G, McCabe NP, Janata J, Elston R, Zhang L, Ialacci S, Chelimsky T.

Clin Auton Res. 2014 Aug;24(4):161-6. doi: 10.1007/s10286-014-0243-0. Epub 2014 Apr 30.

40.

What we know and what we need to know about familial gastroesophageal reflux disease and Barrett's esophagus.

Sun X, Chandar AK, Elston R, Chak A.

Clin Gastroenterol Hepatol. 2014 Oct;12(10):1664-6. doi: 10.1016/j.cgh.2014.03.008. Epub 2014 Mar 19. No abstract available.

PMID:
24657839
41.

It's the Dose, Not the Hypothesis: Reply to.

Page DS, Chapman PM, Landrum PF, Neff J, Elston R.

Hum Ecol Risk Assess. 2014 Apr;20(3):603-606. No abstract available.

42.

Enhancing the power to detect low-frequency variants in genome-wide screens.

Lin CY, Xing G, Ku HC, Elston RC, Xing C.

Genetics. 2014 Apr;196(4):1293-302. doi: 10.1534/genetics.113.160739. Epub 2014 Feb 4.

43.

A generalized genetic random field method for the genetic association analysis of sequencing data.

Li M, He Z, Zhang M, Zhan X, Wei C, Elston RC, Lu Q.

Genet Epidemiol. 2014 Apr;38(3):242-53. doi: 10.1002/gepi.21790. Epub 2014 Jan 30.

44.

A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).

Thameem F, Igo RP Jr, Freedman BI, Langefeld C, Hanson RL, Schelling JR, Elston RC, Duggirala R, Nicholas SB, Goddard KA, Divers J, Guo X, Ipp E, Kimmel PL, Meoni LA, Shah VO, Smith MW, Winkler CA, Zager PG, Knowler WC, Nelson RG, Pahl MV, Parekh RS, Kao WH, Rasooly RS, Adler SG, Abboud HE, Iyengar SK, Sedor JR; Family Investigation of Nephropathy and Diabetes Research Group.

PLoS One. 2013 Dec 17;8(12):e81888. doi: 10.1371/journal.pone.0081888. eCollection 2013.

45.

The null distribution of likelihood-ratio statistics in the conditional-logistic linkage model.

Song YE, Elston RC.

Front Genet. 2013 Nov 19;4:244. doi: 10.3389/fgene.2013.00244. eCollection 2013.

46.

Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial.

Chou S, Boivin G, Ives J, Elston R.

J Infect Dis. 2014 Apr 15;209(8):1219-26. doi: 10.1093/infdis/jit654. Epub 2013 Nov 23.

47.

Will formal genetics become dispensable?

Clerget-Darpoux F, Elston RC.

Hum Hered. 2013;76(2):47-52. doi: 10.1159/000354571. Epub 2013 Oct 2. No abstract available.

48.

PedWiz: a web-based tool for pedigree informatics.

Song YE, Elston RC.

Front Genet. 2013 Sep 25;4:189. doi: 10.3389/fgene.2013.00189. eCollection 2013.

49.

What is the significance of difference in phenotypic variability across SNP genotypes?

Sun X, Elston R, Morris N, Zhu X.

Am J Hum Genet. 2013 Aug 8;93(2):390-7. doi: 10.1016/j.ajhg.2013.06.017. Epub 2013 Aug 1.

50.

Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility.

Thompson CL, Fink SP, Lutterbaugh JD, Elston RC, Veigl ML, Markowitz SD, Li L.

PLoS One. 2013 May 22;8(5):e64122. doi: 10.1371/journal.pone.0064122. Print 2013.

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